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Research Output

  • 1887 Citations
  • 44 Article
  • 3 Review article
  • 1 Chapter
2020

A spontaneous complex structural variant in rcan-1 increases exploratory behavior and laboratory fitness of Caenorhabditis elegans

Zhao, Y., Long, L., Wan, J., Biliya, S., Brady, S. C., Lee, D., Ojemakinde, A., Andersen, E. C., Vannberg, F. O., Lu, H. & McGrath, P. T., 2020, In : PLoS genetics. 16, 2, e1008606.

Research output: Contribution to journalArticle

Open Access

Effects of telomerase overexpression in the model organism Caenorhabditis elegans

Bayat, M., Tanny, R. E., Wang, Y., Herden, C., Daniel, J., Andersen, E. C., Liebau, E. & Waschk, D. E. J., Mar 30 2020, In : Gene. 732, 144367.

Research output: Contribution to journalArticle

The nematode Caenorhabditis elegans and the terrestrial isopod Porcellio scaber likely interact opportunistically

Archer, H., Deiparine, S. & Andersen, E. C., Jun 2020, In : PloS one. 15, 6 June, e0235000.

Research output: Contribution to journalArticle

Open Access
2019

An escape-room inspired game for genetics review

Brady, S. C. & Andersen, E. C., Jan 1 2019, (Accepted/In press) In : Journal of Biological Education.

Research output: Contribution to journalArticle

A novel gene underlies bleomycin-response variation in caenorhabditis elegans

Brady, S. C., Zdraljevic, S., Bisaga, K. W., Tanny, R. E., Cook, D. E., Lee, D., Wang, Y. & Andersen, E. C., 2019, In : Genetics. 212, 4, p. 1453-1468 16 p.

Research output: Contribution to journalArticle

Open Access

Deep sampling of Hawaiian Caenorhabditis elegans reveals high genetic diversity and admixture with global populations

Crombie, T. A., Zdraljevic, S., Cook, D. E., Tanny, R. E., Brady, S. C., Wang, Y., Evans, K. S., Hahnel, S., Lee, D., Rodriguez, B. C., Zhang, G., van der Zwagg, J., Kiontke, K. & Andersen, E. C., Dec 2019, In : eLife. 8, e50465.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Long-read sequencing reveals intra-species tolerance of substantial structural variations and new subtelomere formation in C. elegans

Kim, C., Kim, J., Kim, S., Cook, D. E., Evans, K. S., Andersen, E. C. & Lee, J., Jan 1 2019, In : Genome research. 29, 6, p. 1023-1035 13 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Natural variation and genetic determinants of caenorhabditis elegans sperm size

Gimond, C., Vielle, A., Silva-Soares, N., Zdraljevic, S., McGrath, P. T., Andersen, E. C. & Braendle, C., 2019, In : Genetics. 213, 2, p. 615-632 18 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Natural variation in C. Elegans arsenic toxicity is explained by differences in branched chain amino acid metabolism

Zdraljevic, S., Fox, B. W., Strand, C., Panda, O., Tenjo, F. J., Brady, S. C., Crombie, T. A., Doench, J. G., Schroeder, F. C. & Andersen, E. C., Apr 2019, In : eLife. 8, e40260.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Population Selection and Sequencing of Caenorhabditis elegans Wild Isolates Identifies a Region on Chromosome III Affecting Starvation Resistance

Webster, A. K., Hung, A., Moore, B. T., Guzman, R., Jordan, J. M., Kaplan, R. E. W., Hibshman, J. D., Tanny, R. E., Cook, D. E., Andersen, E. & Ryan Baugh, L., Oct 1 2019, In : G3: Genes, Genomes, Genetics. 9, 10, p. 3477-3488 12 p.

Research output: Contribution to journalArticle

Open Access

Selection and gene flow shape niche-associated variation in pheromone response

Lee, D., Zdraljevic, S., Cook, D. E., Frézal, L., Hsu, J. C., Sterken, M. G., Riksen, J. A. G., Wang, J., Kammenga, J. E., Braendle, C., Félix, M. A., Schroeder, F. C. & Andersen, E. C., Oct 1 2019, In : Nature Ecology and Evolution. 3, 10, p. 1455-1463 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

The caenorhabditis genetics center (CGC) and the caenorhabditis elegans natural diversity resource

Daul, A. L., Andersen, E. C. & Rougvie, A. E., Jan 1 2019, The Biological Resources of Model Organisms. CRC Press, p. 69-94 26 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2018

Discovery of genomic intervals that underlie nematode responses to benzimidazoles

Zamanian, M., Cook, D. E., Zdraljevic, S., Brady, S. C., Lee, D., Lee, J. & Andersen, E. C., Mar 30 2018, In : PLoS Neglected Tropical Diseases. 12, 3, e0006368.

Research output: Contribution to journalArticle

10 Scopus citations

Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resistance to benzimidazoles

Hahnel, S. R., Zdraljevic, S., Rodriguez, B. C., Zhao, Y., McGrath, P. T. & Andersen, E. C., Oct 2018, In : PLoS pathogens. 14, 10, e1007226.

Research output: Contribution to journalArticle

9 Scopus citations

Shared genomic regions underlie natural variation in diverse toxin responses

Evans, K. S., Brady, S. C., Bloom, J. S., Tanny, R. E., Cook, D. E., Giuliani, S. E., Hippleheuser, S. W., Zamanian, M. & Andersen, E. C., Dec 2018, In : Genetics. 210, 4, p. 1509-1525 17 p.

Research output: Contribution to journalArticle

5 Scopus citations
2017

Bacterial Metabolism Affects the C. elegans Response to Cancer Chemotherapeutics

García-González, A. P., Ritter, A. D., Shrestha, S., Andersen, E. C., Yilmaz, L. S. & Walhout, A. J. M., Apr 20 2017, In : Cell. 169, 3, p. 431-441.e8

Research output: Contribution to journalArticle

71 Scopus citations

CeNDR, the Caenorhabditis elegans natural diversity resource

Cook, D. E., Zdraljevic, S., Roberts, J. P. & Andersen, E. C., Jan 1 2017, In : Nucleic acids research. 45, D1, p. D650-D657

Research output: Contribution to journalArticle

54 Scopus citations

Correlations of genotype with climate parameters suggest Caenorhabditis elegans niche adaptations

Evans, K. S., Zhao, Y., Brady, S. C., Long, L., McGrath, P. T. & Andersen, E. C., 2017, In : G3: Genes, Genomes, Genetics. 7, 1, p. 289-298 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Natural diversity facilitates the discovery of conserved chemotherapeutic response mechanisms

Zdraljevic, S. & Andersen, E. C., Dec 2017, In : Current Opinion in Genetics and Development. 47, p. 41-47 7 p.

Research output: Contribution to journalReview article

4 Scopus citations

Natural variation in a single amino acid substitution underlies physiological responses to topoisomerase II poisons

Zdraljevic, S., Strand, C., Seidel, H. S., Cook, D. E., Doench, J. G. & Andersen, E. C., Jul 2017, In : PLoS genetics. 13, 7, e1006891.

Research output: Contribution to journalArticle

13 Scopus citations

Natural Variation in the Distribution and Abundance of Transposable Elements Across the Caenorhabditis elegans Species

Laricchia, K. M., Zdraljevic, S., Cook, D. E. & Andersen, E. C., Sep 1 2017, In : Molecular biology and evolution. 34, 9, p. 2187-2202 16 p.

Research output: Contribution to journalArticle

13 Scopus citations

The genetic basis of natural variation in a phoretic behavior

Lee, D., Yang, H., Kim, J., Brady, S., Zdraljevic, S., Zamanian, M., Kim, H., Paik, Y. K., Kruglyak, L., Andersen, E. C. & Lee, J., Dec 1 2017, In : Nature communications. 8, 1, 273.

Research output: Contribution to journalArticle

16 Scopus citations

VCF-kit: Assorted utilities for the variant call format

Cook, D. E. & Andersen, E. C., May 15 2017, In : Bioinformatics. 33, 10, p. 1581-1582 2 p.

Research output: Contribution to journalArticle

15 Scopus citations
2016

Copper oxide nanoparticles impact several toxicological endpoints and cause neurodegeneration in caenorhabditis elegans

Mashock, M. J., Zanon, T., Kappell, A. D., Petrella, L. N., Andersen, E. C. & Hristova, K. R., Dec 2016, In : PloS one. 11, 12, e0167613.

Research output: Contribution to journalArticle

20 Scopus citations

Mutation is a sufficient and robust predictor of genetic variation for mitotic spindle traits in Caenorhabditis elegans

Farhadifar, R., Ponciano, J. M., Andersen, E. C., Needleman, D. J. & Baer, C. F., Aug 2016, In : Genetics. 203, 4, p. 1859-1870 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Prospects and challenges of CRISPR/Cas genome editing for the study and control of neglected vector-borne nematode diseases

Zamanian, M. & Andersen, E. C., Sep 1 2016, In : FEBS Journal. p. 3204-3221 18 p.

Research output: Contribution to journalReview article

20 Scopus citations

Selection on a Subunit of the NURF Chromatin Remodeler Modifies Life History Traits in a Domesticated Strain of Caenorhabditis elegans

Large, E. E., Xu, W., Zhao, Y., Brady, S. C., Long, L., Butcher, R. A., Andersen, E. C. & McGrath, P. T., Jul 2016, In : PLoS genetics. 12, 7, e1006219.

Research output: Contribution to journalArticle

14 Scopus citations

The genetic basis of natural variation in Caenorhabditis elegans telomere length

Cook, D. E., Zdraljevic, S., Tanny, R. E., Seo, B., Riccardi, D. D., Noble, L. M., Rockman, M. V., Alkema, M. J., Braendle, C., Kammenga, J. E., Wang, J., Kruglyak, L., Félix, M. A., Lee, J. & Andersen, E. C., Sep 2016, In : Genetics. 204, 1, p. 371-383 13 p.

Research output: Contribution to journalArticle

36 Scopus citations
2015

A powerful new quantitative genetics platform, combining caenorhabditis elegans high-throughput fitness assays with a large collection of recombinant strains

Andersen, E. C., Shimko, T. C., Crissman, J. R., Ghosh, R., Bloom, J. S., Seidel, H. S., Gerke, J. P. & Kruglyak, L., Jan 1 2015, In : G3: Genes, Genomes, Genetics. 5, 5, p. 911-920 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

A Wild C. Elegans Strain Has Enhanced Epithelial Immunity to a Natural Microsporidian Parasite

Balla, K. M., Andersen, E. C., Kruglyak, L. & Troemel, E. R., 2015, In : PLoS pathogens. 11, 2, e1004583.

Research output: Contribution to journalArticle

20 Scopus citations

Remarkably divergent regions punctuate the genome assembly of the Caenorhabditis elegans hawaiian strain CB4856

Thompson, O. A., Snoek, L. B., Nijveen, H., Sterken, M. G., Volkers, R. J. M., Brenchley, R., van’t Hof, A., Bevers, R. P. J., Cossins, A. R., Yanai, I., Hajnal, A., Schmid, T., Perkins, J. D., Spencer, D., Kruglyak, L., Andersen, E. C., Moerman, D. G., Hillier, L. D. W., Kammenga, J. E. & Waterston, R. H., Jul 1 2015, In : Genetics. 200, 3, p. 975-989 15 p.

Research output: Contribution to journalArticle

43 Scopus citations

Scaling, selection, and evolutionary dynamics of the mitotic spindle

Farhadifar, R., Baer, C. F., Valfort, A. C., Andersen, E. C., Müller-Reichert, T., Delattre, M. & Needleman, D. J., Mar 16 2015, In : Current Biology. 25, 6, p. 732-740 9 p.

Research output: Contribution to journalArticle

36 Scopus citations

The laboratory domestication of Caenorhabditis elegans

Sterken, M. G., Snoek, L. B., Kammenga, J. E. & Andersen, E. C., May 1 2015, In : Trends in Genetics. 31, 5, p. 224-231 8 p.

Research output: Contribution to journalReview article

62 Scopus citations

The red death meets the abdominal bristle: Polygenic mutation for susceptibility to a bacterial pathogen in Caenorhabditis elegans

Etienne, V., Andersen, E. C., Ponciano, J. M., Blanton, D., Cadavid, A., Joyner-Matos, J., Matsuba, C., Tabman, B. & Baer, C. F., Feb 1 2015, In : Evolution. 69, 2, p. 508-519 12 p.

Research output: Contribution to journalArticle

4 Scopus citations
2014

A Variant in the Neuropeptide Receptor npr-1 is a Major Determinant of Caenorhabditis elegans Growth and Physiology

Andersen, E. C., Bloom, J. S., Gerke, J. P. & Kruglyak, L., Feb 2014, In : PLoS genetics. 10, 2, e1004156.

Research output: Contribution to journalArticle

51 Scopus citations

COPASutils: An R package for reading, processing, and visualizing data from copas large-particle flow cytometers

Shimko, T. C. & Andersen, E. C., Oct 20 2014, In : PloS one. 9, 10, 0111090.

Research output: Contribution to journalArticle

12 Scopus citations
2013

Species richness, distribution and genetic diversity of Caenorhabditis nematodes in a remote tropical rainforest

Félix, M. A., Jovelin, R., Ferrari, C., Han, S., Cho, Y. R., Andersen, E. C., Cutter, A. D. & Braendle, C., 2013, In : BMC Evolutionary Biology. 13, 1, 10.

Research output: Contribution to journalArticle

38 Scopus citations
2012

Chromosome-scale selective sweeps shape Caenorhabditis elegans genomic diversity

Andersen, E. C., Gerke, J. P., Shapiro, J. A., Crissman, J. R., Ghosh, R., Bloom, J. S., Félix, M. A. & Kruglyak, L., Mar 2012, In : Nature Genetics. 44, 3, p. 285-290 6 p.

Research output: Contribution to journalArticle

193 Scopus citations

Natural variation in a chloride channel subunit confers avermectin resistance in C. elegans

Ghosh, R., Andersen, E. C., Shapiro, J. A., Gerke, J. P. & Kruglyak, L., Feb 3 2012, In : Science. 335, 6068, p. 574-578 5 p.

Research output: Contribution to journalArticle

76 Scopus citations
2011
5 Scopus citations
2010

Differential localization and independent acquisition of the H3K9me2 and H3K9me3 chromatin modifications in the Caenorhabditis elegans adult germ line

Bessler, J. B., Andersen, E. C. & Villeneuve, A. M., Jan 2010, In : PLoS genetics. 6, 1, e1000830.

Research output: Contribution to journalArticle

62 Scopus citations

Variability in gene expression underlies incomplete penetrance

Raj, A., Rifkin, S. A., Andersen, E. & Van Oudenaarden, A., Feb 18 2010, In : Nature. 463, 7283, p. 913-918 6 p.

Research output: Contribution to journalArticle

400 Scopus citations
2009

A polymorphism in npr-1 is a behavioral determinant of pathogen susceptibility in C. elegans

Reddy, K. C., Andersen, E. C., Kruglyak, L. & Kim, D. H., Jan 16 2009, In : Science. 323, 5912, p. 382-384 3 p.

Research output: Contribution to journalArticle

133 Scopus citations
2008

Multiple levels of redundant processes inhibit Caenorhabditis elegans vulval cell fates

Andersen, E. C., Saffer, A. M. & Horvitz, H. R., Aug 2008, In : Genetics. 179, 4, p. 2001-2012 12 p.

Research output: Contribution to journalArticle

15 Scopus citations
2007

DPL-1 DP, LIN-35 Rb and EFL-1 E2F act with the MCD-1 zinc-finger protein to promote programmed cell death in Caenorhabditis elegans

Reddien, P. W., Andersen, E. C., Huang, M. C. & Horvitz, H. R., Apr 2007, In : Genetics. 175, 4, p. 1719-1733 15 p.

Research output: Contribution to journalArticle

29 Scopus citations

Two C. elegans histone methyltransferases repress lin-3 EGF transcription to inhibit vulval development

Andersen, E. C. & Horvitz, H. R., Aug 1 2007, In : Development. 134, 16, p. 2991-2999 9 p.

Research output: Contribution to journalArticle

90 Scopus citations
2006

C. elegans ISWI and NURF301 antagonize an Rb-like pathway in the determination of multiple cell fates

Andersen, E. C., Lu, X. & Horvitz, H. R., Jul 2006, In : Development. 133, 14, p. 2695-2704 10 p.

Research output: Contribution to journalArticle

40 Scopus citations
2001

Patterns of gene expression during Drosophila mesoderm development

Furlong, E. E. M., Andersen, E. C., Null, B., White, K. P. & Scott, M. P., Aug 31 2001, In : Science. 293, 5535, p. 1629-1633 5 p.

Research output: Contribution to journalArticle

214 Scopus citations