Grants per year
Personal profile
Research Interests
My primary research interest is in health outcomes following pediatric liver transplantation and acute liver failure. I lead a research group that studies all aspects of outcomes from survival to health related quality of life (HRQOL). Our research group has extensive experience examining HRQOL and cognitive outcomes in pediatric liver transplant survivors, long term complications related to immunosuppressive medications and the causes and treatment of acute liver failure. Our group has also actively involved in new trials of immunosuppression withdrawal in liver transplant recipients. I am also one of the leaders of the Pediatric Acute Liver Failure Network and lead several ancillary studies within this group.
I am the Medical Director of the Siragusa Transplant Center and provide leadership and support for the missions of the solid organ transplant programs at Lurie Children's.
I am the Associate Chair for Clinical Services for the Department of Pediatrics and Pediatric Executive Leader of the Ambulatory Leadership Committee at Ann and Robert H Lurie Children's Hospital. My clinical practice includes treatment of all forms of chronic liver disease in childhood and management of children following liver transplantation. My special areas of clinical focus include acute liver failure, complications of cirrhosis and withdrawal of immunosuppression following liver transplantation.
Certifications and Licenses
Transplant Hepatology | |
Pediatric Transplant Hepatology | |
Pediatric Gastroenterology |
Training Experience
1988 | Residency, Northwestern University, McGaw Medical Center (Children’s Memorial Hospital) |
1990 | Fellowship, Univ. of Chicago Hospital |
Education/Academic qualification
Medicine, MD, Northwestern University
… → 1985
Research interests keywords
- Health Services Research
- Inflammatory Bowel Disease
- Liver Disease / Pathobiology
- Outcome Measures
- Patient-Reported Outcomes
- Pediatric Gastroenterology
- Transplantation
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Collaborations and top research areas from the last five years
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ChiLDReN, the Childhood Liver Disease Research Network
National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health
9/18/19 → 5/31/24
Project: Research project
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ChiLDReN, the Childhood Liver Disease Research Network
Alonso, E. M., Bass, L. M., Melin-Aldana, H. & Taylor, S. A.
National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health
9/18/19 → 5/31/24
Project: Research project
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PALF TReatment for ImmUne Mediated PathopHysiology (TRIUMPH)
National Institute of Diabetes and Digestive and Kidney Diseases
9/21/18 → 8/31/20
Project: Research project
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PALF TReatment for ImmUne Mediated PathopHysiology (TRIUMPH)
National Institute of Diabetes and Digestive and Kidney Diseases
9/21/18 → 8/31/20
Project: Research project
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ChiLDReN PSC Observational study
University of Colorado Boulder, National Institute of Diabetes and Digestive and Kidney Diseases
9/18/18 → 5/31/19
Project: Research project
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Acute-on-chronic liver failure before liver transplantation does not impact post-transplant survival in children with biliary atresia
Banc-Husu, A. M., Hall, M., Thurm, C., Whitehead, B. A., Godown, J. A. & Alonso, E. M., May 2023, In: Liver Transplantation. 29, 5, p. 485-496 12 p.Research output: Contribution to journal › Article › peer-review
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Adenovirus is Not Detected in Liver Tissue From a Historical Multicenter Cohort of Children With Acute Liver Failure
Chapin, C. A., Diamond, T., Harris, R. M., Vaccaro, O., Loomes, K. M., Alonso, E. M. & Behrens, E. M., Sep 1 2023, In: Journal of pediatric gastroenterology and nutrition. 77, 3, p. 393-395 3 p.Research output: Contribution to journal › Article › peer-review
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Effector memory CD8 T-cells as a novel peripheral blood biomarker for activated Tcell pediatric acute liver failure
Chapin, C. A., Burn, T. M., Diamond, T., Loomes, K. M., Alonso, E. M. & Behrens, E. M., Jun 2023, In: PloS one. 18, 6 June, e0286394.Research output: Contribution to journal › Article › peer-review
Open Access -
Genotype-phenotype relationships of truncating mutations, p.E297G and p.D482G in bile salt export pump deficiency
the NAtural course and Prognosis of PFIC and Effect of biliary Diversion (NAPPED) Consortium, Feb 2023, In: JHEP Reports. 5, 2, 100626.Research output: Contribution to journal › Article › peer-review
Open Access -
Heterogeneous liver on research ultrasound identifies children with cystic fibrosis at high risk of advanced liver disease
Siegel, M. J., Leung, D. H., Molleston, J. P., Ye, W., Paranjape, S. M., Freeman, A. J., Palermo, J. J., Stoll, J., Masand, P., Karmazyn, B., Harned, R., Ling, S. C., Navarro, O. M., Karnsakul, W., Alazraki, A., Schwarzenberg, S. J., Towbin, A. J., Alonso, E. M., Nicholas, J. L., Green, N., & 3 others , Jul 2023, In: Journal of Cystic Fibrosis. 22, 4, p. 745-755 11 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations