Eugene Y Xu

  • 1176 Citations

Research output per year

If you made any changes in Pure these will be visible here soon.

Personal profile

Research Interests

The overall goal of my research program is to understand the mechanisms of mammalian reproduction, in particular, how germline stem cells, meiosis and gamete differentiation, are regulated in mammals, using combined genetic, development and evolutionary approaches. We work with both mouse and Drosophila systems as well as cell culture to characterize the roles of highly conserved components of regulatory machinery for stem cell and reproductive development. We are also interested in translational research which extends our findings from animal models into reproductive medicine, in particular in our battles against reproductive cancers and infertility.

Education/Academic qualification

PhD, The University of Chicago

… → 1996

Research interests

  • Cancer Biology
  • Cancer: Female Reproductive System (ovary, cervix, uterus)
  • Developmental Biology
  • Gametogenesis
  • Genetics
  • Oncology
  • Reproduction
  • Stem Cells

Fingerprint Dive into the research topics where Eugene Y Xu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output

  • 1176 Citations
  • 22 Article
  • 4 Review article
  • 1 Conference contribution

DAZL is a master translational regulator of murine spermatogenesis

Li, H., Liang, Z., Yang, J., Wang, D., Wang, H., Zhu, M., Geng, B. & Xu, E. Y., May 1 2019, In : National Science Review. 6, 3, p. 455-468 14 p.

Research output: Contribution to journalArticle

Open Access
  • 4 Scopus citations

    Histopathological Image Analysis on Mouse Testes for Automated Staging of Mouse Seminiferous Tubule

    Xu, J., Lu, H., Li, H., Wang, X., Madabhushi, A. & Xu, Y., Jan 1 2019, Digital Pathology - 15th European Congress, ECDP 2019, Proceedings. Reyes-Aldasoro, C. C., Janowczyk, A., Veta, M., Bankhead, P. & Sirinukunwattana, K. (eds.). Springer Verlag, p. 117-124 8 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11435 LNCS).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  • Mammalian Pum1 and Pum2 Control Body Size via Translational Regulation of the Cell Cycle Inhibitor Cdkn1b

    Lin, K., Qiang, W., Zhu, M., Ding, Y., Shi, Q., Chen, X., Zsiros, E., Wang, K., Yang, X., Kurita, T. & Xu, E. Y., Feb 26 2019, In : Cell reports. 26, 9, p. 2434-2450.e6

    Research output: Contribution to journalArticle

    Open Access
  • 6 Scopus citations

    Essential requirement of mammalian Pumilio family in embryonic development

    Lin, K., Zhang, S., Shi, Q., Zhu, M., Gao, L., Xia, W., Geng, B., Zheng, Z. & Xu, E. Y., Nov 26 2018, In : Molecular biology of the cell. 29, 24, p. 2922-2932 11 p.

    Research output: Contribution to journalArticle

  • 2 Scopus citations

    Generation and functional characterization of a conditional Pumilio2 null allele

    Lin, K., Zhang, S., Chen, J., Yang, D., Zhu, M. & Xu, E. Y., Jan 1 2018, In : Journal of Biomedical Research. 32, 6, p. 434-441 8 p.

    Research output: Contribution to journalArticle

    Open Access
  • 3 Scopus citations