• 2564 Citations
20032020
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Personal profile

Research Interests

Our research is focused on the role of viral microRNAs in herpesviral oncogenesis

Education/Academic qualification

PhD, Heidelberg University

… → 2005

Research interests

  • MicroRNA
  • Viral Oncology
  • Virology

Fingerprint Dive into the research topics where Eva Gottwein is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 11 Similar Profiles
MicroRNAs Medicine & Life Sciences
Human Herpesvirus 8 Medicine & Life Sciences
Primary Effusion Lymphoma Medicine & Life Sciences
microRNA Agriculture & Biology
Human herpesvirus 8 Agriculture & Biology
HIV-1 Medicine & Life Sciences
B-Lymphocytes Medicine & Life Sciences
Herpesviridae Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2009 2020

Human Herpesvirus 8
MicroRNAs
Neoplasms
Kaposi's Sarcoma
Oncogenes
Human Herpesvirus 8
MicroRNAs
Kaposi's Sarcoma
Primary Effusion Lymphoma
Endothelial Cells
Primary Effusion Lymphoma
Essential Genes
Human Herpesvirus 8
Cell Line
Clustered Regularly Interspaced Short Palindromic Repeats

Research Output 2003 2019

  • 2564 Citations
  • 23 Article
  • 3 Review article
  • 2 Chapter

Genome-wide CRISPR screens reveal genetic mediators of cereblon modulator toxicity in primary effusion lymphoma

Patil, A., Manzano, M. & Gottwein, E., Jul 23 2019, In : Blood Advances. 3, 14, p. 2105-2117 13 p.

Research output: Contribution to journalArticle

Open Access
Clustered Regularly Interspaced Short Palindromic Repeats
Primary Effusion Lymphoma
Genome
Gene Silencing
Cullin Proteins
4 Citations (Scopus)

CK1a and IRF4 are essential and independent effectors of immunomodulatory drugs in primary effusion lymphoma

Patil, A., Manzano, M. & Gottwein, E., Aug 9 2018, In : Blood. 132, 6, p. 577-586 10 p.

Research output: Contribution to journalArticle

Casein Kinase I
Primary Effusion Lymphoma
Cells
Pharmaceutical Preparations
Toxicity
5 Citations (Scopus)

Gene essentiality landscape and druggable oncogenic dependencies in herpesviral primary effusion lymphoma

Manzano, M., Patil, A., Waldrop, A., Dave, S. S., Behdad, A. & Gottwein, E., Dec 1 2018, In : Nature communications. 9, 1, 3263.

Research output: Contribution to journalArticle

Primary Effusion Lymphoma
cultured cells
genes
Genes
Cells
12 Citations (Scopus)

Divergent target recognition by coexpressed 5′-isomiRs of miR-142-3p and selective viral mimicry

Manzano, M., Forte, E., Raja, A. N., Schipma, M. J. & Gottwein, E., Sep 1 2015, In : RNA. 21, 9, p. 1606-1620 15 p.

Research output: Contribution to journalArticle

MicroRNAs
Binding Sites
Vertebrates
Actins
Seeds
14 Citations (Scopus)

MicroRNA-mediated transformation by the Kaposi's sarcomaassociated herpesvirus Kaposin locus

Forte, E., Raja, A. N., Shamulailatpam, P., Manzano, M., Schipma, M. J., Casey, J. L. & Gottwein, E., Jan 1 2015, In : Journal of virology. 89, 4, p. 2333-2341 9 p.

Research output: Contribution to journalArticle

Herpesviridae
MicroRNAs
microRNA
Human herpesvirus 8
Human Herpesvirus 8