Grants per year
Personal profile
Research Interests
Our research is focused on the role of viral microRNAs in herpesviral oncogenesis
Education/Academic qualification
Biology, PhD, Heidelberg University
… → 2005
Research interests keywords
- MicroRNA
- Viral Oncology
- Virology
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Dive into the research topics where Eva Gottwein is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Gottwein & Braun Collab Innovation
National Institute of Allergy and Infectious Diseases
4/1/20 → 4/30/25
Project: Research project
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Transcriptional Control of Cellular Survival and Proliferation in KSHV-transformed B Cells
Gottwein, E., Bartom, E. T. & Ntziachristos, P.
3/1/20 → 3/31/25
Project: Research project
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KSHV-induced oncogenic changes in a primary human lymphatic endothelial cell model of Kaposi's Sarcoma
8/1/21 → 7/31/23
Project: Research project
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Deregulation of tumor suppressive pathways by KSHV microRNAs
7/1/16 → 6/30/21
Project: Research project
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CRISPR screens identify novel regulators of cFLIP dependency and ligand-independent, TRAIL-R1-mediated cell death
Kuehnle, N., Osborne, S. M., Liang, Z., Manzano, M. & Gottwein, E., May 2023, In: Cell Death and Differentiation. 30, 5, p. 1221-1234 14 p.Research output: Contribution to journal › Article › peer-review
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Druggable host gene dependencies in primary effusion lymphoma
Kuehnle, N. & Gottwein, E., Oct 2022, In: Current Opinion in Virology. 56, 101270.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
Kaposi’s sarcoma-associated herpesvirus drives a super-enhancer-mediated survival gene expression program in primary effusion lymphoma
Manzano, M., Günther, T., Ju, H., Nicholas, J., Bartom, E. T., Grundhoff, A. & Gottwein, E., Jul 1 2020, In: mBio. 11, 4, p. 1-23 23 p., e01457-20.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Primary effusion lymphoma enhancer connectome links super-enhancers to dependency factors
Wang, C., Zhang, L., Ke, L., Ding, W., Jiang, S., Li, D., Narita, Y., Hou, I., Liang, J., Li, S., Xiao, H., Gottwein, E., Kaye, K. M., Teng, M. & Zhao, B., Dec 2020, In: Nature communications. 11, 1, 6318.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
Genome-wide CRISPR screens reveal genetic mediators of cereblon modulator toxicity in primary effusion lymphoma
Patil, A., Manzano, M. & Gottwein, E., Jul 23 2019, In: Blood Advances. 3, 14, p. 2105-2117 13 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations
Datasets
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microRNA Targetome Analysis of Latently KSHV-infected Primary Effusion Lymphoma Cell lines Using PAR-CLIP [Illumina]
Gottwein, E. (Contributor), Mukherjee, N. (Contributor), Hafner, M. (Contributor), Shamulailatpam, P. (Contributor), Tuschl, T. (Contributor) & Ohler, U. (Contributor), ArrayExpress, 2011
https://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-32109
Dataset
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Unambiguous Identification of miRNA:target site Interactions by Different Types of Ligation Reactions
Grosswendt, S. (Contributor), Filipchyk, A. (Contributor), Manzano, M. (Contributor), Klironomos, F. (Contributor), Schilling, M. (Contributor), Herzog, M. (Contributor), Gottwein, E. (Contributor) & Rajewsky, N. (Contributor), Gene Expression Omnibus, 2014
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE56180
Dataset
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The viral and cellular microRNA targetome in lymphoblastoid cell lines
Gottwein, E. (Contributor), Kang, D. (Contributor), Hafner, M. (Contributor), Feederle, R. (Contributor), Tuschl, T. (Contributor) & Ohler, U. (Contributor), ArrayExpress, 2012
https://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-41437
Dataset
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Morrison et al. mRNA expression dependence on miRNA seed presence
Bartom, E. T. (Creator) & Gottwein, E. (Creator), Code Ocean, 2019
DOI: 10.24433/co.1360162.v1, https://codeocean.com/capsule/5364796/tree/v1
Dataset