• 864 Citations
20042020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2020

Employing bicontinuous-to-micellar transitions in nanostructure morphology for on-demand photo-oxidation responsive cytosolic delivery and off-on cytotoxicity

Bobbala, S., Allen, S. D., Yi, S., Vincent, M., Frey, M., Karabin, N. B. & Scott, E. A., Mar 7 2020, In : Nanoscale. 12, 9, p. 5332-5340 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

High density display of an anti-angiogenic peptide on micelle surfaces enhances their inhibition of αvβ3 integrin-mediated neovascularization in vitro

Nagaraj, R., Stack, T., Yi, S., Mathew, B., Shull, K. R., Scott, E. A., Mathew, M. T. & Bijukumar, D. R., Mar 2020, In : Nanomaterials. 10, 3, 581.

Research output: Contribution to journalArticle

Open Access

Super-Resolution Imaging of Self-Assembled Nanocarriers Using Quantitative Spectroscopic Analysis for Cluster Extraction

Davis, J. L., Zhang, Y., Yi, S., Du, F., Song, K. H., Scott, E. A., Sun, C. & Zhang, H. F., Mar 10 2020, In : Langmuir. 36, 9, p. 2291-2299 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

XCage: A Tricyclic Octacationic Receptor for Perylene Diimide with Picomolar Affinity in Water

Liu, W., Bobbala, S., Stern, C. L., Hornick, J. E., Liu, Y., Enciso, A. E., Scott, E. A. & Fraser Stoddart, J., Feb 12 2020, In : Journal of the American Chemical Society. 142, 6, p. 3165-3173 9 p.

Research output: Contribution to journalArticle

1 Scopus citations
2019

A review on recent advancements in ophthalmology devices: Currently in market and under clinical trials

Nagaraj, R., Bijukumar, D. R., Mathew, B., Scott, E. A. & Mathew, M. T., Aug 1 2019, In : Journal of Drug Delivery Science and Technology. 52, p. 334-345 12 p.

Research output: Contribution to journalReview article

1 Scopus citations

A Supramolecular Approach for Modulated Photoprotection, Lysosomal Delivery, and Photodynamic Activity of a Photosensitizer

Roy, I., Bobbala, S., Young, R. M., Beldjoudi, Y., Nguyen, M. T., Cetin, M. M., Cooper, J. A., Allen, S., Anamimoghadam, O., Scott, E. A., Wasielewski, M. R. & Stoddart, J. F., Aug 7 2019, In : Journal of the American Chemical Society. 141, 31, p. 12296-12304 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Biomimetic Magnetic Nanostructures: A Theranostic Platform Targeting Lipid Metabolism and Immune Response in Lymphoma

Singh, A., Nandwana, V., Rink, J. S., Ryoo, S. R., Chen, T. H., Allen, S. D., Scott, E. A., Gordon, L. I., Thaxton, C. S. & Dravid, V. P., Sep 24 2019, In : ACS nano. 13, 9, p. 10301-10311 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Celastrol-loaded PEG-: B -PPS nanocarriers as an anti-inflammatory treatment for atherosclerosis

Allen, S. D., Liu, Y. G., Kim, T., Bobbala, S., Yi, S., Zhang, X., Choi, J. & Scott, E. A., Feb 2019, In : Biomaterials Science. 7, 2, p. 657-668 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Magnetic nanostructure-loaded bicontinuous nanospheres for magnetic resonance imaging and drug delivery

Modak, M., Nandwana, V., Dravid, V. P. & Scott, E. A., Jan 1 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

On the advancement of polymeric bicontinuous nanospheres toward biomedical applications

Allen, S. D., Bobbala, S., Karabin, N. B. & Scott, E. A., Mar 2019, In : Nanoscale Horizons. 4, 2, p. 321-338 18 p.

Research output: Contribution to journalReview article

7 Scopus citations

Surface Engineered Polymersomes for Enhanced Modulation of Dendritic Cells During Cardiovascular Immunotherapy

Yi, S., Zhang, X., Sangji, M. H., Liu, Y., Allen, S. D., Xiao, B., Bobbala, S., Braverman, C. L., Cai, L., Hecker, P. I., DeBerge, M., Thorp, E. B., Temel, R. E., Stupp, S. I. & Scott, E. A., Oct 1 2019, In : Advanced Functional Materials. 29, 42, 1904399.

Research output: Contribution to journalArticle

5 Scopus citations

Versatile assembly of polymeric bicontinuous nanospheres via flash nanoprecipitation

Bobbala, S., Allen, S., Karabin, N. & Scott, E. A., Jan 1 2019, Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting. Society for Biomaterials, 1 p. (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; vol. 40).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2018

Benchmarking Bicontinuous Nanospheres against Polymersomes for in Vivo Biodistribution and Dual Intracellular Delivery of Lipophilic and Water-Soluble Payloads

Allen, S. D., Bobbala, S., Karabin, N. B., Modak, M. & Scott, E. A., Oct 10 2018, In : ACS Applied Materials and Interfaces. 10, 40, p. 33857-33866 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

ExTzBox: A Glowing Cyclophane for Live-Cell Imaging

Roy, I., Bobbala, S., Zhou, J., Nguyen, M. T., Nalluri, S. K. M., Wu, Y., Ferris, D. P., Scott, E. A., Wasielewski, M. R. & Stoddart, J. F., Jun 13 2018, In : Journal of the American Chemical Society. 140, 23, p. 7206-7212 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

Flash nanoprecipitation permits versatile assembly and loading of polymeric bicontinuous cubic nanospheres

Bobbala, S., Allen, S. D. & Scott, E. A., Mar 21 2018, In : Nanoscale. 10, 11, p. 5078-5088 11 p.

Research output: Contribution to journalArticle

20 Scopus citations

Immune theranostics

Scott, E. A., Dec 1 2018, In : Bridge. 48, 4, p. 35-39 5 p.

Research output: Contribution to journalComment/debate

Induction of mycobacterium tuberculosislipid-specific t cell responses by pulmonary delivery of mycolic acid-loaded polymeric micellar nanocarriers

Shang, S., Kats, D., Cao, L., Morgun, E., Velluto, D., He, Y., Xu, Q., Wang, C. R. & Scott, E. A., Nov 27 2018, In : Frontiers in immunology. 9, NOV, 02709.

Research output: Contribution to journalArticle

6 Scopus citations

Influences of nanocarrier morphology on therapeutic immunomodulation

Frey, M., Bobbala, S., Karabin, N. & Scott, E., Jan 1 2018, In : Nanomedicine. 13, 14, p. 1795-1811 17 p.

Research output: Contribution to journalReview article

5 Scopus citations

Modulation of Schlemm's canal endothelial cell stiffness via latrunculin loaded block copolymer micelles

Stack, T., Vahabikashi, A., Johnson, M. & Scott, E., Jul 2018, In : Journal of Biomedical Materials Research - Part A. 106, 7, p. 1771-1779 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Polymersomes scalably fabricated via flash nanoprecipitation are non-toxic in non-human primates and associate with leukocytes in the spleen and kidney following intravenous administration

Allen, S. D., Liu, Y. G., Bobbala, S., Cai, L., Hecker, P. I., Temel, R. & Scott, E. A., Oct 1 2018, In : Nano Research. 11, 10, p. 5689-5703 15 p.

Research output: Contribution to journalArticle

9 Scopus citations
1 Scopus citations

Sequential intracellular release of water-soluble cargos from Shell-crosslinked polymersomes

Du, F., Bobbala, S., Yi, S. & Scott, E. A., Jul 28 2018, In : Journal of Controlled Release. 282, p. 90-100 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Sustained micellar delivery via inducible transitions in nanostructure morphology

Karabin, N. B., Allen, S., Kwon, H. K., Bobbala, S., Firlar, E., Shokuhfar, T., Shull, K. R. & Scott, E. A., Dec 1 2018, In : Nature communications. 9, 1, 624.

Research output: Contribution to journalArticle

20 Scopus citations
2017

Acute CD47 Blockade During Ischemic Myocardial Reperfusion Enhances Phagocytosis-Associated Cardiac Repair

Zhang, S., Yeap, X. Y., DeBerge, M., Naresh, N. K., Wang, K., Jiang, Z., Wilcox, J. E., White, S. M., Morrow, J. P., Burridge, P. W., Procissi, D., Scott, E. A., Frazier, W. & Thorp, E. B., Aug 2017, In : JACC: Basic to Translational Science. 2, 4, p. 386-397 12 p.

Research output: Contribution to journalArticle

8 Scopus citations

Facile assembly and loading of theranostic polymersomes via multi-impingement flash nanoprecipitation

Allen, S., Osorio, O., Liu, Y. G. & Scott, E., Sep 28 2017, In : Journal of Controlled Release. 262, p. 91-103 13 p.

Research output: Contribution to journalArticle

27 Scopus citations
10 Scopus citations

Overcoming Immune Dysregulation with Immunoengineered Nanobiomaterials

Scott, E. A., Karabin, N. B. & Augsornworawat, P., Jun 21 2017, In : Annual Review of Biomedical Engineering. 19, p. 57-84 28 p.

Research output: Contribution to journalArticle

9 Scopus citations

Toll-like receptor 8 agonist nanoparticles mimic immunomodulating effects of the live BCG vaccine and enhance neonatal innate and adaptive immune responses

Dowling, D. J., Scott, E. A., Scheid, A., Bergelson, I., Joshi, S., Pietrasanta, C., Brightman, S., Sanchez-Schmitz, G., Van Haren, S. D., Ninković, J., Kats, D., Guiducci, C., de Titta, A., Bonner, D. K., Hirosue, S., Swartz, M. A., Hubbell, J. A. & Levy, O., Nov 2017, In : Journal of Allergy and Clinical Immunology. 140, 5, p. 1339-1350 12 p.

Research output: Contribution to journalArticle

49 Scopus citations
2016

Engineering Nanomaterials to Address Cell-Mediated Inflammation in Atherosclerosis

Allen, S. D., Liu, Y. G. & Scott, E. A., 2016, In : Regenerative Engineering and Translational Medicine. 2, 1, p. 37-50 14 p.

Research output: Contribution to journalArticle

19 Scopus citations

Tailoring Nanostructure Morphology for Enhanced Targeting of Dendritic Cells in Atherosclerosis

Yi, S., Allen, S. D., Liu, Y. G., Ouyang, B. Z., Li, X., Augsornworawat, P., Thorp, E. B. & Scott, E. A., Dec 27 2016, In : ACS nano. 10, 12, p. 11290-11303 14 p.

Research output: Contribution to journalArticle

29 Scopus citations
2014

Controlled Release Strategies in Tissue Engineering

Rice, J. J., Martino, M. M., Scott, E. A. & Hubbell, J. A., Dec 10 2014, Tissue Engineering: Second Edition. Elsevier Inc, p. 347-392 46 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Vesicle photonics in biology with a focus on single cell analysis

Vasdekis, A. E., Scott, E. A., Hubbell, J. A. & Saltis, D., Dec 22 2014, 2014 IEEE Photonics Conference, IPC 2014. Institute of Electrical and Electronics Engineers Inc., p. 3-4 2 p. 6994960. (2014 IEEE Photonics Conference, IPC 2014).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2013

Optical manipulation of vesicles for optofluidic applications

Vasdekis, A. E., Scott, E. A., O'Neil, C. P., Psaltis, D. & Hubbell, J. A., Dec 11 2013, Optical Trapping and Optical Micromanipulation X. Vol. 8810. 88101R

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Tunable T cell immunity towards a protein antigen using polymersomes vs. solid-core nanoparticles

Stano, A., Scott, E. A., Dane, K. Y., Swartz, M. A. & Hubbell, J. A., Jun 1 2013, In : Biomaterials. 34, 17, p. 4339-4346 8 p.

Research output: Contribution to journalArticle

63 Scopus citations

Vesicle photonics

Vasdekis, A. E., Scott, E. A., Roke, S., Hubbell, J. A. & Psaltis, D., Jul 1 2013, In : Annual Review of Materials Research. 43, p. 283-305 23 p.

Research output: Contribution to journalReview article

12 Scopus citations
2012

Dendritic cell activation and T cell priming with adjuvant- and antigen-loaded oxidation-sensitive polymersomes

Scott, E. A., Stano, A., Gillard, M., Maio-Liu, A. C., Swartz, M. A. & Hubbell, J. A., Sep 1 2012, In : Biomaterials. 33, 26, p. 6211-6219 9 p.

Research output: Contribution to journalArticle

101 Scopus citations

Exposure of the lysine in the gamma chain dodecapeptide of human fibrinogen is not enhanced by adsorption to poly(ethylene terephthalate) as measured by biotinylation and mass spectrometry

Ovod, V., Scott, E. A., Flake, M. M., Parker, S. R., Bateman, R. J. & Elbert, D. L., Mar 1 2012, In : Journal of Biomedical Materials Research - Part A. 100 A, 3, p. 622-631 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Precision intracellular delivery based on optofluidic polymersome rupture

Vasdekis, A. E., Scott, E. A., O'Neil, C. P., Psaltis, D. & Hubbell, J. A., Sep 25 2012, In : ACS nano. 6, 9, p. 7850-7857 8 p.

Research output: Contribution to journalArticle

53 Scopus citations
2011

Colloidal materials for modulating the immune response

Hubbell, J. A., Swartz, M. A., Simeoni, E., Stano, A., Nembrini, C., Ballester, M., Thomas, S. N., Hirosue, S., Van Der Vlies, A. J., O'Neil, C. P., Velluto, D., Eby, J. & Scott, E. A., Jan 1 2011, Materials Engineering and Sciences Division - Core Programming Topic at the 2011 AIChE Annual Meeting. AIChE, p. 537-539 3 p. (Materials Engineering and Sciences Division - Core Programming Topic at the 2011 AIChE Annual Meeting; vol. 1).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Dendritic cell targeting by polymersomes for vaccine development

Stano, A., Scott, E., Simeoni, E., Nembrini, C., Swartz, M. & Hubbell, J., Dec 1 2011, 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials, ESB 2011.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2010

Modular scaffolds assembled around living cells using poly(ethylene glycol) microspheres with macroporation via a non-cytotoxic porogen

Scott, E. A., Nichols, M. D., Kuntz-Willits, R. & Elbert, D. L., Jan 1 2010, In : Acta Biomaterialia. 6, 1, p. 29-38 10 p.

Research output: Contribution to journalArticle

73 Scopus citations
2009

Factors affecting size and swelling of poly(ethylene glycol) microspheres formed in aqueous sodium sulfate solutions without surfactants

Nichols, M. D., Scott, E. A. & Elbert, D. L., Oct 1 2009, In : Biomaterials. 30, 29, p. 5283-5291 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

Use of lorenz titanium implants in orbital fracture repair

Chang, S. H., Custer, P. L., Mohadjer, Y. & Scott, E., Mar 1 2009, In : Ophthalmic Plastic and Reconstructive Surgery. 25, 2, p. 119-122 4 p.

Research output: Contribution to journalArticle

7 Scopus citations
2008

Covalent layer-by-layer strategies for biomaterials coatings

Elbert, D. L., Kim, J. & Scott, E. A., Dec 1 2008, 8th World Biomaterials Congress 2008. 1 p. (8th World Biomaterials Congress 2008; vol. 1).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Endothelial cell migration on RGD-peptide-containing PEG hydrogels in the presence of sphingosine 1-phosphate

Wacker, B. K., Alford, S. K., Scott, E. A., Thakur, M. D., Longmore, G. D. & Elbert, D. L., Jan 1 2008, In : Biophysical Journal. 94, 1, p. 273-285 13 p.

Research output: Contribution to journalArticle

44 Scopus citations

Protein adsorption and cell adhesion on nanoscale bioactive coatings formed from poly(ethylene glycol) and albumin microgels

Scott, E. A., Nichols, M. D., Cordova, L. H., George, B. J., Jun, Y. S. & Elbert, D. L., Dec 1 2008, In : Biomaterials. 29, 34, p. 4481-4493 13 p.

Research output: Contribution to journalArticle

69 Scopus citations

Stable isotope labeling tandem mass spectrometry (SILT): Integration with peptide identification and extension to data-dependent scans

Elbert, D. L., Mawuenyega, K. G., Scott, E. A., Wildsmith, K. R. & Bateman, R. J., Oct 1 2008, In : Journal of Proteome Research. 7, 10, p. 4546-4556 11 p.

Research output: Contribution to journalArticle

11 Scopus citations
2007

Mass spectrometric mapping of fibrinogen conformations at poly(ethylene terephthalate) interfaces

Scott, E. A. & Elbert, D. L., Sep 1 2007, In : Biomaterials. 28, 27, p. 3904-3917 14 p.

Research output: Contribution to journalArticle

16 Scopus citations
2006

Delivery of Sphingosine 1-phosphate from poly(ethylene glycol) hydrogels

Wacker, B. K., Scott, E. A., Kaneda, M. M., Alford, S. K. & Elbert, D. L., Apr 1 2006, In : Biomacromolecules. 7, 4, p. 1335-1343 9 p.

Research output: Contribution to journalArticle

46 Scopus citations
2005

In vitro and in vivo analysis of antide delivery from multi-phase microspheres fabricated via solvent removal

Branton, J. F., Cheifetz, P. M., Scott, E. A., Bubbers, E. J. & Mathiowitz, E., Nov 29 2005, In : Israel Journal of Chemistry. 45, 4, p. 445-456 12 p.

Research output: Contribution to journalArticle