Franck Potet

  • 1055 Citations
20012022
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Personal profile

Research Interests

My goal is to investigate structure-function relationships between cytoplasmic Ca2+-sensing domains and their regulation by calmodulin in the cardiac sodium channel Nav1.5.

Research Interests

My goal is to investigate structure-function relationships between cytoplasmic Ca2+-sensing domains and their regulation by calmodulin in the cardiac sodium channel Nav1.5.

Education/Academic qualification

PhD, Paris XI-Orsay University of Science

… → 2003

Keywords

  • Arrhythmias
  • Electrophysiology

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Grants 2014 2022

Epilepsy
Brain Diseases
Mutation
Drug Approval
Pharmacology
Long QT Syndrome
Genetic Testing
Mutation
Aptitude
Surface Properties
Long QT Syndrome
Mutation
Genes
Cardiac Arrhythmias
Alleles
Long QT Syndrome
Sudden Infant Death
Cardiac Arrhythmias
Sudden Death
Mutation
EF Hand Motifs
Calcium
Calmodulin
Mutation
Voltage-Gated Sodium Channels

Research Output 2001 2018

  • 1055 Citations
  • 21 Article
2 Citations

A Mechanism of Calmodulin Modulation of the Human Cardiac Sodium Channel

Johnson, C. N., Potet, F., Thompson, M. K., Kroncke, B. M., Glazer, A. M., Voehler, M. W., Knollmann, B. C., George Jr, A. L. & Chazin, W. J., May 1 2018, In : Structure. 26, 5, p. 683-694.e3

Research output: Contribution to journalArticle

Sodium Channels
Calmodulin
Calcium
Magnetic Resonance Spectroscopy
Binding Sites
7 Citations

Use-dependent block of human cardiac sodium channels by GS967

Potet, F., Vanoye, C. G. & George Jr, A. L., Jul 1 2016, In : Molecular Pharmacology. 90, 1, p. 52-60 9 p.

Research output: Contribution to journalArticle

Sodium Channels
Local Anesthetics
Anesthetics
6-(4-(trifluoromethoxy)phenyl)-3-(trifluoromethyl)(1,2,4)triazolo(4,3-a)pyridine
Sodium
7 Citations

Intracellular Calcium Attenuates Late Current Conducted by Mutant Human Cardiac Sodium Channels

Potet, F., Beckermann, T. M., Kunic, J. D. & George Jr, A. L., Jan 1 2015, In : Circulation: Arrhythmia and Electrophysiology. 8, 4, p. 933-941 9 p.

Research output: Contribution to journalArticle

Sodium Channels
Calcium
Voltage-Gated Sodium Channels
Cardiac Arrhythmias
Mutation
20 Citations

Gremlin 2 promotes differentiation of embryonic stem cells to atrial fate by activation of the signaling pathway

Tanwar, V., Bylund, J. B., Hu, J., Yan, J., Walthall, J. M., Mukherjee, A., Heaton, W. H., Wang, W. D., Potet, F., Rai, M., Kupershmidt, S., Knapik, E. W. & Hatzopoulos, A. K., Jan 1 2014, In : Stem Cells. 32, 7, p. 1774-1788 15 p.

Research output: Contribution to journalArticle

Embryonic Stem Cells
Cardiac Myocytes
Cardiac Arrhythmias
Stem Cells
Pluripotent Stem Cells
28 Citations

Novel SCN5A mutation in amiodarone-responsive multifocal ventricular ectopy-associated cardiomyopathy

Beckermann, T. M., McLeod, K., Murday, V., Potet, F. & George, A. L., Jan 1 2014, In : Heart rhythm. 11, 8, p. 1446-1453 8 p.

Research output: Contribution to journalArticle

Amiodarone
Cardiomyopathies
Mutation
Cardiac Arrhythmias
Sodium