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Frank Dieter Eckerdt

  • 1082 Citations
20022024
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Personal profile

Training Experience

2004Postdoctoral Fellowship, J. W. Goethe University

Education/Academic qualification

PhD, J. W. Goethe University

… → 2003

Fingerprint Dive into the research topics where Frank Dieter Eckerdt is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 4 Similar Profiles
Phosphotransferases Medicine & Life Sciences
Medulloblastoma Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Glioblastoma Medicine & Life Sciences
Neoplastic Stem Cells Medicine & Life Sciences
Cyclin B1 Medicine & Life Sciences
Glioma Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2019 2024

Development of Novel MNK Inhibitors for Treating Glioblastoma

Clutter, M., Eckerdt, F. D., Horbinski, C. M., James, C. D., Mishra, R. K., Platanias, L. C. & Schiltz, G. E.

National Institute of Neurological Disorders and Stroke

9/1/19 → 6/30/24

Project: Research project

Glioblastoma
Stem Cells
Phosphotransferases
Cell Survival
Survival

Research Output 2002 2019

  • 1082 Citations
  • 24 Article
  • 3 Review article
  • 2 Comment/debate
  • 1 Short survey

Pharmacological mTOR targeting enhances the antineoplastic effects of selective PI3Kα inhibition in medulloblastoma

Eckerdt, F., Clymer, J., Bell, J. B., Beauchamp, E. M., Blyth, G. T., Goldman, S. & Platanias, L. C., Dec 1 2019, In : Scientific reports. 9, 1, 12822.

Research output: Contribution to journal › Article

Open Access
Medulloblastoma
Phosphatidylinositol 3-Kinases
Antineoplastic Agents
Pharmacology
Neoplastic Stem Cells
1 Citation (Scopus)

Potent antineoplastic effects of combined PI3Kα-MNK inhibition in medulloblastoma

Eckerdt, F., Bell, J. B., Beauchamp, E. M., Clymer, J., Blyth, G. T., Kosciuczuk, E. M., Ma, Q., Chen, D. Z., Horbinski, C., Goldman, S., Munshi, H. G., Hashizume, R. & Platanias, L. C., Jun 1 2019, In : Molecular Cancer Research. 17, 6, p. 1305-1315 11 p.

Research output: Contribution to journal › Article

Medulloblastoma
Mitogen-Activated Protein Kinase Kinases
Phosphatidylinositol 3-Kinases
Antineoplastic Agents
Neoplastic Stem Cells

Antineoplastic effects of selective CDK9 inhibition with atuveciclib on cancer stem-like cells in triple-negative breast cancer

Brisard, D., Eckerdt, F., Marsh, L. A., Blyth, G. T., Jain, S., Cristofanilli, M., Horiuchi, D. & Platanias, L. C., Dec 1 2018, In : Oncotarget. 9, 99, p. 37305-37318 14 p.

Research output: Contribution to journal › Article

Cyclin-Dependent Kinase 9
Triple Negative Breast Neoplasms
Neoplastic Stem Cells
Antineoplastic Agents
Recurrence
8 Citations (Scopus)

Differential response of glioma stem cells to arsenic trioxide therapy is regulated by MNK1 and mRNA translation

Bell, J. B., Eckerdt, F., Dhruv, H. D., Finlay, D., Peng, S., Kim, S., Kroczynska, B., Beauchamp, E. M., Alley, K., Clymer, J., Goldman, S., Cheng, S. Y., James, C. D., Nakano, I., Horbinski, C., Mazar, A. P., Vuori, K., Kumthekar, P., Raizer, J., Berens, M. E. & 1 others, Platanias, L. C., Jan 2018, In : Molecular Cancer Research. 16, 1, p. 32-46 15 p.

Research output: Contribution to journal › Article

MAP Kinase Kinase 1
Protein Biosynthesis
Glioma
Stem Cells
Glioblastoma
8 Citations (Scopus)

HDL nanoparticles targeting sonic hedgehog subtype medulloblastoma

Bell, J. B., Rink, J. S., Eckerdt, F., Clymer, J., Goldman, S., Thaxton, C. S. & Platanias, L. C., Dec 1 2018, In : Scientific reports. 8, 1, 1211.

Research output: Contribution to journal › Article

Medulloblastoma
Nanoparticles
HDL Lipoproteins
Scavenger Receptors
Ewing's Sarcoma