Personal profile

Research Interests

Research in the Turek laboratory is focused on the study of sleep and circadian rhythms, with special interest in identifying genes that regulate sleep and circadian rhythms. Ongoing work on sleep and circadian rhythms includes an investigation of: (1) the neurochemical, molecular, and cellular events involved in the entrainment, generation and expression of circadian rhythms arising from a central biological clock located in the suprachiasmatic nucleus (SCN) of the hypothalamus, (2) the genetics of the circadian clock system and the molecular genetic mechanisms underlying the sleep-wake cycle, (3) the feedback effects of the sleep-wake cycle on the circadian clock regulating the timing of that cycle, (4) the effects of advanced age on the expression of behavioral and endocrine rhythms, and on the expression of circadian clock genes, 5) the links between sleep, circadian rhythms and energy metabolism and, (6) the role of melatonin in modulating sleep and circadian rhythms. In addition to our work on rodents, we have established extensive collaborations with clinical researchers. Studies in humans are aimed at shifting the human clock in an attempt to alleviate mental and physical problems that are associated with disorders in circadian time-keeping, particularly in the elderly and in shift-workers. In addition, we are using both pharmacological and non-pharmacological approaches to determine if we can reverse the effects of aging on the circadian clock system in both rodents and humans. Our sleep, circadian and metabolic studies are focused on how disruption in these interactions can lead to obesity, diabetes and CVD.

Training Experience

2008Management Skills for innovative University Leaders at Kellogg School of Management, Northwestern University. Certificate Executive Course

Certifications and Licenses

1969Teaching Certificate, issued by Michigan State University

Keywords

  • Obesity
  • Reproduction
  • Sleep
  • Genomics
  • Sleep Disorders
  • Aging
  • Depression
  • Genetics
  • Circadian Rhythms

Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Research Output 1971 2017

Timing of meals: When is as critical as what and how much

Jiang, P. & Turek, F. W. May 1 2017 In : American Journal of Physiology - Endocrinology and Metabolism. 312, 5, p. E369-E380

Research output: Contribution to journalReview article

Circadian Clocks
Meals
Life Style
Epidemiologic Studies
Molecular Biology
4 Citations

Circadian clocks: Not your grandfather's clock

Turek, F. W. Nov 25 2016 In : Science. 354, 6315, p. 992-993 2 p.

Research output: Contribution to journalShort survey

Circadian Clocks
Medicine
Gene Regulatory Networks
Circadian Rhythm
Cell Body
6 Citations

Circadian rhythms, metabolism, and chrononutrition in rodents and humans

Johnston, J. D., Ordovás, J. M., Scheer, F. A. & Turek, F. W. 2016 In : Advances in Nutrition. 7, 2, p. 399-406 8 p.

Research output: Contribution to journalArticle

circadian rhythm
metabolism
organisms
Circadian Rhythm
Rodentia
1 Citations

Circadian Rhythms in Gastrointestinal Health and Diseases

Bishehsari, F., Levi, F., Turek, F. W. & Keshavarzian, A. Sep 1 2016 In : Gastroenterology. 151, 3, p. e1-e5

Research output: Contribution to journalArticle

Gastrointestinal Diseases
Circadian Rhythm
Health

Introduction: Genetics and Genomics of Sleep

Turek, F. W. & Allada, R. 2016 Principles and Practice of Sleep Medicine . Kryger, M. H., Roth, T. & Dement, W. C. (eds.). 6 ed. Elsevier, p. 270-271 2 p.

Research output: Chapter in Book/Report/Conference proceedingChapter