Personal profile

Research Interests

Research in the Turek laboratory is focused on the study of sleep and circadian rhythms, with special interest in identifying genes that regulate sleep and circadian rhythms. Ongoing work on sleep and circadian rhythms includes an investigation of: (1) the neurochemical, molecular, and cellular events involved in the entrainment, generation and expression of circadian rhythms arising from a central biological clock located in the suprachiasmatic nucleus (SCN) of the hypothalamus, (2) the genetics of the circadian clock system and the molecular genetic mechanisms underlying the sleep-wake cycle, (3) the feedback effects of the sleep-wake cycle on the circadian clock regulating the timing of that cycle, (4) the effects of advanced age on the expression of behavioral and endocrine rhythms, and on the expression of circadian clock genes, 5) the links between sleep, circadian rhythms and energy metabolism and, (6) the role of melatonin in modulating sleep and circadian rhythms. In addition to our work on rodents, we have established extensive collaborations with clinical researchers. Studies in humans are aimed at shifting the human clock in an attempt to alleviate mental and physical problems that are associated with disorders in circadian time-keeping, particularly in the elderly and in shift-workers. In addition, we are using both pharmacological and non-pharmacological approaches to determine if we can reverse the effects of aging on the circadian clock system in both rodents and humans. Our sleep, circadian and metabolic studies are focused on how disruption in these interactions can lead to obesity, diabetes and CVD.

Training Experience

2008Management Skills for innovative University Leaders at Kellogg School of Management, Northwestern University. Certificate Executive Course

Certifications and Licenses

1969Teaching Certificate, issued by Michigan State University

Keywords

  • Obesity
  • Reproduction
  • Sleep
  • Genomics
  • Sleep Disorders
  • Aging
  • Depression
  • Genetics
  • Circadian Rhythms

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Research Output 1971 2017

4 Citations

Health consequences of electric lighting practices in the modern world: A report on the National Toxicology Program's workshop on shift work at night, artificial light at night, and circadian disruption

Lunn, R. M. , Blask, D. E. , Coogan, A. N. , Figueiro, M. G. , Gorman, M. R. , Hall, J. E. , Hansen, J. , Nelson, R. J. , Panda, S. , Smolensky, M. H. , Stevens, R. G. , Turek, F. W. , Vermeulen, R. , Carreón, T. , Caruso, C. C. , Lawson, C. C. , Thayer, K. A. , Twery, M. J. , Ewens, A. D. , Garner, S. C. & 2 others Schwingl, P. J. & Boyd, W. A. Dec 31 2017 In : Science of the Total Environment. 607-608, p. 1073-1084 12 p.

Research output: Research - peer-reviewReview article

toxicology
lighting
programme
health
Electric lighting

Timing of meals: When is as critical as what and how much

Jiang, P. & Turek, F. W. May 1 2017 In : American Journal of Physiology - Endocrinology and Metabolism. 312, 5, p. E369-E380

Research output: Research - peer-reviewReview article

Circadian Clocks
Meals
Epidemiologic Studies
Molecular Biology
Animal Models
5 Citations

Circadian clocks: Not your grandfather's clock

Turek, F. W. Nov 25 2016 In : Science. 354, 6315, p. 992-993 2 p.

Research output: Research - peer-reviewShort survey

Circadian Clocks
Medicine
Grandparents
Gene Regulatory Networks
Circadian Rhythm
9 Citations

Circadian rhythms, metabolism, and chrononutrition in rodents and humans

Johnston, J. D., Ordovás, J. M., Scheer, F. A. & Turek, F. W. Jan 1 2016 In : Advances in Nutrition. 7, 2, p. 399-406 8 p.

Research output: Research - peer-reviewArticle

circadian rhythm
rodents
metabolism
organisms
tissues
2 Citations

Circadian Rhythms in Gastrointestinal Health and Diseases

Bishehsari, F., Levi, F., Turek, F. W. & Keshavarzian, A. Sep 1 2016 In : Gastroenterology. 151, 3, p. e1-e5

Research output: Research - peer-reviewArticle

Gastrointestinal Diseases
Circadian Rhythm
Health