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Research Output 1971 2018

2018

Cross-species systems analysis identifies gene networks differentially altered by sleep loss and depression

Scarpa, J. R., Jiang, P., Gao, V. D., Fitzpatrick, K., Millstein, J., Olker, C., Gotter, A., Winrow, C. J., Renger, J. J., Kasarskis, A., Turek, F. W. & Vitaterna, M. H., Jul 25 2018, In : Science Advances. 4, 7, eaat1294

Research output: Contribution to journalArticle

Genes
Systems analysis
Sleep
Gene expression
Brain

Session 2 Discussion: Clocks, Hormones and the Environment

Turek, F., Almoosawi, S., Woods, S., Kanoski, S. & Gwin, J., Sep 1 2018, In : Physiology and Behavior. 193, p. 232-233 2 p.

Research output: Contribution to journalComment/debate

Hormones
Circadian Clocks
Biological Phenomena
Precision Medicine
Energy Metabolism
Biomedical Research
2017
20 Citations

Health consequences of electric lighting practices in the modern world: A report on the National Toxicology Program's workshop on shift work at night, artificial light at night, and circadian disruption

Lunn, R. M. , Blask, D. E. , Coogan, A. N. , Figueiro, M. G. , Gorman, M. R. , Hall, J. E. , Hansen, J. , Nelson, R. J. , Panda, S. , Smolensky, M. H. , Stevens, R. G. , Turek, F. W. , Vermeulen, R. , Carreón, T. , Caruso, C. C. , Lawson, C. C. , Thayer, K. A. , Twery, M. J. , Ewens, A. D. , Garner, S. C. & 2 others Schwingl, P. J. & Boyd, W. A., Dec 31 2017, In : Science of the Total Environment. 607-608, p. 1073-1084 12 p.

Research output: Contribution to journalReview article

Electric lighting
toxicology
Health
sleep
Health hazards
3 Citations

Timing of meals: When is as critical as what and how much

Jiang, P. & Turek, F. W., May 1 2017, In : American Journal of Physiology - Endocrinology and Metabolism. 312, 5, p. E369-E380

Research output: Contribution to journalReview article

Circadian Clocks
Meals
Epidemiologic Studies
Molecular Biology
Animal Models
2016
1 Citations

Altered Body Weight Regulation in CK1ϵ Null and tau Mutant Mice on Regular Chow and High Fat Diets

Zhou, L., Summa, K. C., Olker, C., Vitaterna, M. H. & Turek, F. W., Jan 1 2016, In : Genetics Research International. 2016, 4973242

Research output: Contribution to journalArticle

Photoperiod
High Fat Diet
Body Weight
Circadian Rhythm
Casein Kinase Iepsilon
8 Citations

Circadian clocks: Not your grandfather's clock

Turek, F. W., Nov 25 2016, In : Science. 354, 6315, p. 992-993 2 p.

Research output: Contribution to journalShort survey

Circadian Clocks
Medicine
Gene Regulatory Networks
Circadian Rhythm
Grandparents
22 Citations

Circadian rhythms, metabolism, and chrononutrition in rodents and humans

Johnston, J. D., Ordovás, J. M., Scheer, F. A. & Turek, F. W., Jan 1 2016, In : Advances in Nutrition. 7, 2, p. 399-406 8 p.

Research output: Contribution to journalArticle

Circadian Rhythm
circadian rhythm
Rodentia
rodents
human physiology
5 Citations

Circadian Rhythms in Gastrointestinal Health and Diseases

Bishehsari, F., Levi, F., Turek, F. W. & Keshavarzian, A., Sep 1 2016, In : Gastroenterology. 151, 3, p. e1-e5

Research output: Contribution to journalArticle

Gastrointestinal Diseases
Circadian Rhythm
Health

Introduction: Genetics and Genomics of Sleep

Turek, F. W. & Allada, R., 2016, Principles and Practice of Sleep Medicine . Kryger, M. H., Roth, T. & Dement, W. C. (eds.). 6 ed. Elsevier, p. 270-271 2 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

10 Citations

Light/dark shifting promotes alcohol-induced colon carcinogenesis: Possible role of intestinal inflammatory milieu and microbiota

Bishehsari, F., Saadalla, A., Khazaie, K., Engen, P. A., Voigt, R. M., Shetuni, B. B., Forsyth, C., Shaikh, M., Vitaterna, M. H., Turek, F. & Keshavarzian, A., Dec 2 2016, In : International Journal of Molecular Sciences. 17, 12, 2017

Research output: Contribution to journalArticle

Microbiota
Colon
Carcinogenesis
alcohols
Alcohols
1 Citations

Multiple classifier systems for automatic sleep scoring in mice

Gao, V., Turek, F. & Vitaterna, M., May 1 2016, In : Journal of Neuroscience Methods. 264, p. 33-39 7 p.

Research output: Contribution to journalArticle

Sleep
Decision Trees
Electromyography
Discriminant Analysis
Sample Size
15 Citations

Night workers with circadian misalignment are susceptible to alcohol-induced intestinal hyperpermeability with social drinking

Swanson, G. R., Gorenz, A., Shaikh, M., Desai, V., Kaminsky, T., van Den Berg, J., Murphy, T., Raeisi, S., Fogg, L., Vitaterna, M. H., Forsyth, C., Turek, F., Burgess, H. J. & Keshavarzian, A., Jul 1 2016, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 311, 1, p. G192-G201

Research output: Contribution to journalArticle

Drinking
Alcohols
Permeability
Alcoholic Liver Diseases
Melatonin
4 Citations

Systems Genetic Analyses Highlight a TGFβ-FOXO3 Dependent Striatal Astrocyte Network Conserved across Species and Associated with Stress, Sleep, and Huntington’s Disease

Scarpa, J. R., Jiang, P., Losic, B., Readhead, B., Gao, V. D., Dudley, J. T., Vitaterna, M. H., Turek, F. W. & Kasarskis, A., Jul 1 2016, In : PLoS Genetics. 12, 7, e1006137

Research output: Contribution to journalArticle

Corpus Striatum
sleep
astrocytes
Huntington Disease
Astrocytes
20 Citations

The Circadian Clock Mutation Promotes Intestinal Dysbiosis

Voigt, R. M., Summa, K. C., Forsyth, C. B., Green, S. J., Engen, P., Naqib, A., Vitaterna, M. H., Turek, F. W. & Keshavarzian, A., Feb 1 2016, In : Alcoholism: Clinical and Experimental Research. 40, 2, p. 335-347 13 p.

Research output: Contribution to journalArticle

Dysbiosis
Circadian Clocks
Clocks
Nutrition
Alcohols
2015
12 Citations

A Systems Approach Identifies Networks and Genes Linking Sleep and Stress: Implications for Neuropsychiatric Disorders

Jiang, P., Scarpa, J. R., Fitzpatrick, K., Losic, B., Gao, V. D., Hao, K., Summa, K. C., Yang, H. S., Zhang, B., Allada, R., Vitaterna, M. H., Turek, F. W. & Kasarskis, A., Jan 1 2015, In : Cell reports. 11, 5, p. 835-848 14 p.

Research output: Contribution to journalArticle

Gene Regulatory Networks
Systems Analysis
Sleep
Genes
Organizations
8 Citations

Chronic Alcohol Exposure and the Circadian Clock Mutation Exert Tissue-Specific Effects on Gene Expression in Mouse Hippocampus, Liver, and Proximal Colon

Summa, K. C., Jiang, P., Fitzpatrick, K., Voigt, R. M., Bowers, S. J., Forsyth, C. B., Vitaterna, M. H., Keshavarzian, A. & Turek, F. W., Oct 1 2015, In : Alcoholism: Clinical and Experimental Research. 39, 10, p. 1917-1929 13 p.

Research output: Contribution to journalArticle

Circadian Clocks
Gene expression
Liver
Clocks
Hippocampus
15 Citations

Environmental Disruption of Circadian Rhythm Predisposes Mice to Osteoarthritis-Like Changes in Knee Joint

Kc, R., Li, X., Voigt, R. M., Ellman, M. B., Summa, K. C., Vitaterna, M. H., Keshavarizian, A., Turek, F. W., Meng, Q. J., Stein, G. S., van Wijnen, A. J., Chen, D., Forsyth, C. B. & Im, H. J., Sep 1 2015, In : Journal of Cellular Physiology. 230, 9, p. 2174-2183 10 p.

Research output: Contribution to journalArticle

Knee Joint
Circadian Rhythm
Osteoarthritis
Tissue Inhibitor of Metalloproteinase-3
Cartilage
5 Citations

Induction of osteoarthritis-like pathologic changes by chronic alcohol consumption in an experimental mouse model

Kc, R., Voigt, R., Li, X., Forsyth, C. B., Ellman, M. B., Summa, K. C., Turek, F. W., Keshavarzian, A., Kim, J. S. & Im, H. J., Jan 1 2015, In : Arthritis and Rheumatology. 67, 6, p. 1678-1680 3 p.

Research output: Contribution to journalArticle

8 Citations

Metabolic effects of bariatric surgery in mouse models of circadian disruption

Arble, D. M., Sandoval, D. A., Turek, F. W., Woods, S. C. & Seeley, R. J., Aug 6 2015, In : International Journal of Obesity. 39, 8, p. 1310-1318 9 p.

Research output: Contribution to journalArticle

Bariatric Surgery
Gastrectomy
Obesity
Body Weight
Genetic Models
16 Citations

Neurobiology of circadian rhythm regulation

Rosenwasser, A. M. & Turek, F. W., Jan 1 2015, In : Sleep Medicine Clinics. 10, 4, p. 403-412 10 p.

Research output: Contribution to journalArticle

Circadian Clocks
Suprachiasmatic Nucleus
Neurobiology
Circadian Rhythm
Neurochemistry
3 Citations

New approach for analyzing self-reporting of insomnia symptoms reveals a high rate of comorbid insomnia across a wide spectrum of chronic diseases

Katic, B., Heywood, J., Turek, F., Chiauzzi, E., Vaughan, T. E., Simacek, K., Wicks, P., Jain, S., Winrow, C. & Renger, J. J., Jan 1 2015, In : Sleep Medicine. 16, 11, p. 1332-1341 10 p., 2866

Research output: Contribution to journalArticle

Sleep Initiation and Maintenance Disorders
Chronic Disease
Odds Ratio
Fibromyalgia
Depressive Disorder
27 Citations
Eczema
Atopic Dermatitis
Circadian Rhythm
Sleep
Direction compound
10 Citations

Osteoarthritis-like pathologic changes in the knee joint induced by environmental disruption of circadian rhythms is potentiated by a high-fat diet

Kc, R., Li, X., Forsyth, C. B., Voigt, R. M., Summa, K. C., Vitaterna, M. H., Tryniszewska, B., Keshavarzian, A., Turek, F. W., Meng, Q. J. & Im, H. J., Nov 20 2015, In : Scientific Reports. 5, 16896

Research output: Contribution to journalArticle

High Fat Diet
Knee Joint
Circadian Rhythm
Osteoarthritis
Feeding Behavior
3 Citations

Selective pharmacological blockade of the 5-HT7 receptor attenuates light and 8-OH-DPAT induced phase shifts of mouse circadian wheel running activity

Shelton, J., Yun, S., Olson, S. L., Turek, F., Bonaventure, P., Dvorak, C., Lovenberg, T. & Dugovic, C., Jan 15 2015, In : Frontiers in Behavioral Neuroscience. 8, JAN, 453

Research output: Contribution to journalArticle

8-Hydroxy-2-(di-n-propylamino)tetralin
Running
Pharmacology
Light
Circadian Rhythm
1 Citations
Sexism
Publications
Biomedical Research
Chromosomes
3 Citations

The clocks within Us

Summa, K. C. & Turek, F. W., Jan 1 2015, In : Scientific American. 312, 2, p. 51-55 5 p.

Research output: Contribution to journalArticle

2014
3 Citations

Biomedical Effects of Circadian Rhythm Disturbances

Summa, K. C. & Turek, F. W., 2014, Impact of Sleep and Sleep Disturbances on Obesity and Cancer. Redline, S. & Berger, N. A. (eds.). Springer New York, p. 77-101 25 p. (Energy Balance and Cancer; vol. 8)

Research output: Chapter in Book/Report/Conference proceedingChapter

Biochemical Phenomena
Circadian Rhythm
Physiological Phenomena
Biological Phenomena
Suprachiasmatic Nucleus
29 Citations

Chronobiology and obesity: Interactions between circadian rhythms and energy regulation

Summa, K. C. & Turek, F. W., Jan 1 2014, In : Advances in Nutrition. 5, 3, p. 312S-319S

Research output: Contribution to journalArticle

Circadian Clocks
Circadian Rhythm
circadian rhythm
obesity
Obesity

Circadian Desynchrony and Health

Summa, K. C. & Turek, F. W., 2014, Atlas of Clinical Sleep Medicine. Kryger, M. H., Avidan, A. Y. & Berry, R. (eds.). 2 ed. Saunders, p. 140-147 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

92 Citations

Circadian disorganization alters intestinal microbiota

Voigt, R. M., Forsyth, C. B., Green, S. J., Mutlu, E., Engen, P., Vitaterna, M. H., Turek, F. W. & Keshavarzian, A., May 21 2014, In : PloS one. 9, 5, e97500

Research output: Contribution to journalArticle

Dysbiosis
Microbiota
Photoperiod
Nutrition
Circadian Rhythm
86 Citations

Circadian melatonin rhythm and excessive daytime sleepiness in Parkinson disease

Videnovic, A., Noble, C., Reid, K. J., Peng, J., Turek, F. W., Marconi, A., Rademaker, A. W., Simuni, T., Zadikoff, C. & Zee, P. C., Jan 1 2014, In : JAMA Neurology. 71, 4, p. 463-469 7 p.

Research output: Contribution to journalArticle

Melatonin
Circadian Rhythm
Parkinson Disease
Sleep
Area Under Curve
18 Citations

Commentary: "leaning in" to support sex differences in basic science and clinical research

Woodruff, T. K., Kibbe, M. R., Paller, A. S., Turek, F. W. & Woolley, C. S., Apr 1 2014, In : Endocrinology. 155, 4, p. 1181-1183 3 p.

Research output: Contribution to journalComment/debate

Career Choice
Sex Factors
Sex Distribution
Sex Characteristics
Patient Selection
7 Citations

The circadian clock gene Csnk1e regulates rapid eye movement sleep amount, and nonrapid eye movement sleep architecture in mice

Zhou, L., Bryant, C. D., Loudon, A., Palmer, A. A., Vitaterna, M. H. & Turek, F. W., Apr 1 2014, In : Sleep. 37, 4, p. 785-793 9 p.

Research output: Contribution to journalArticle

Casein Kinase Iepsilon
Circadian Clocks
REM Sleep
Eye Movements
Sleep
3 Citations

Validation of video motion-detection scoring of forced swim test in mice

Gao, V., Vitaterna, M. H. & Turek, F. W., Sep 30 2014, In : Journal of Neuroscience Methods. 235, p. 59-64 6 p.

Research output: Contribution to journalArticle

Hybrid Vigor
Research Design
Antidepressive Agents
Software
Color
2013
5 Citations

Animal care practices in experiments on biological rhythms and sleep: Report of the Joint Task Force of the Society for Research on Biological Rhythms and the Sleep Research Society

Bittman, E. L., Kilduff, T. S., Kriegsfeld, L. J., Szymusiak, R., Toth, L. A. & Turek, F. W., Jul 1 2013, In : Journal of the American Association for Laboratory Animal Science. 52, 4, p. 437-443 7 p.

Research output: Contribution to journalArticle

biological rhythms
animal care
sleep
Institutional Animal Care and Use Committee
medical sciences

Discovery of the clock mutant and the first mammalian clock gene and the links to obesity: Starting with animal #25

Turek, F. W., Nov 1 2013, Chronobiology and Obesity. Springer New York, p. 1-9 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Clocks
Animals
Obesity
Genes
Circadian Clocks
75 Citations

Disruption of the Circadian Clock in Mice Increases Intestinal Permeability and Promotes Alcohol-Induced Hepatic Pathology and Inflammation

Summa, K. C., Voigt, R. M., Forsyth, C. B., Shaikh, M., Cavanaugh, K., Tang, Y., Vitaterna, M. H., Song, S., Turek, F. W. & Keshavarzian, A., Jun 18 2013, In : PLoS One. 8, 6, e67102

Research output: Contribution to journalArticle

Circadian Clocks
liver diseases
Pathology
endotoxins
Endotoxins

Respect the clock

Zee, P. C. & Turek, F. W., Dec 1 2013, In : Sleep Medicine Reviews. 17, 6, p. 395-397 3 p.

Research output: Contribution to journalEditorial

Work Schedule Tolerance
Circadian Rhythm Sleep Disorders
Metabolic Syndrome X
Oxidative Stress
26 Citations

Role for intestinal CYP2E1 in alcohol-induced circadian gene-mediated intestinal hyperpermeability

Forsyth, C. B., Voigt, R. M., Shaikh, M., Tang, Y., Cederbaum, A. I., Turek, F. W. & Keshavarzian, A., Jul 15 2013, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 305, 2

Research output: Contribution to journalArticle

Cytochrome P-450 CYP2E1
Protein Isoforms
Alcohols
CLOCK Proteins
Genes
2012
18 Citations

Altered sleep and affect in the neurotensin receptor 1 knockout mouse

Fitzpatrick, K., Winrow, C. J., Gotter, A. L., Millstein, J., Arbuzova, J., Brunner, J., Kasarskis, A., Vitaterna, M. H., Renger, J. J. & Turek, F. W., Jul 1 2012, In : Sleep. 35, 7, p. 949-956 8 p.

Research output: Contribution to journalArticle

Knockout Mice
Sleep
Quantitative Trait Loci
REM Sleep
Mood Disorders
3 Citations

Circadian rhythms in neuroendocrine systems

Arble, D. M., Copinschi, G., Vitaterna, M. H., Van Cauter, E. & Turek, F. W., Dec 1 2012, Handbook of Neuroendocrinology. Elsevier Inc, p. 271-305 35 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Neurosecretory Systems
Circadian Rhythm
Sleep
Pituitary Hormone-Releasing Hormones
Ghrelin
32 Citations

Csnk1e is a genetic regulator of sensitivity to psychostimulants and opioids

Bryant, C. D., Parker, C. C., Zhou, L., Olker, C., Chandrasekaran, R. Y., Wager, T. T., Bolivar, V. J., Loudon, A. S., Vitaterna, M. H., Turek, F. W. & Palmer, A. A., Mar 1 2012, In : Neuropsychopharmacology. 37, 4, p. 1026-1035 10 p.

Research output: Contribution to journalArticle

Methamphetamine
Opioid Analgesics
Fentanyl
Quantitative Trait Loci
Locomotion
41 Citations

Environmental perturbation of the Circadian clock disrupts pregnancy in the mouse

Summa, K. C., Vitaterna, M. H. & Turek, F. W., May 23 2012, In : PLoS One. 7, 5, e37668

Research output: Contribution to journalArticle

Circadian Clocks
circadian rhythm
Clocks
Photoperiod
pregnancy
10 Citations

High-resolution mapping of a novel genetic locus regulating voluntary physical activity in mice

Yang, H. S., Shimomura, K., Vitaterna, M. H. & Turek, F. W., Feb 1 2012, In : Genes, Brain and Behavior. 11, 1, p. 113-124 12 p.

Research output: Contribution to journalArticle

Genetic Loci
Chromosomes, Human, Pair 13
Genes
Cocaine
Efferent Pathways
16 Citations

Identification of causal genes, networks, and transcriptional regulators of REM sleep and wake

Millstein, J., Winrow, C. J., Kasarskis, A., Owens, J. R., Zhou, L., Summa, K. C., Fitzpatrick, K., Zhang, B., Vitaterna, M. H., Schadt, E. E., Renger, J. J. & Turek, F. W., Nov 1 2011, In : Sleep. 34, 11, p. 1469-1477 9 p.

Research output: Contribution to journalArticle

Gene Regulatory Networks
REM Sleep
Sleep
Thalamus
Mammals
2 Citations

Molecular neurobiology of circadian rhythms

Turek, F. W. & Vitaterna, M. H., Jan 1 2011, In : Handbook of Clinical Neurology. 99, C, p. 951-961 11 p.

Research output: Contribution to journalArticle

Circadian Rhythm Signaling Peptides and Proteins
Molecular Models
Neurobiology
Gene Expression Regulation
Circadian Rhythm
4 Citations
Microdissection
Gene Expression Profiling
RNA
Gene expression
Dissection
6 Citations

Pharmacological validation of candidate causal sleep genes identified in an N2 cross

Brunner, J. I., Gotter, A. L., Millstein, J., Garson, S., Binns, J., Fox, S. V., Savitz, A. T., Yang, H. S., Fitzpatrick, K., Zhou, L., Owens, J. R., Webber, A. L., Vitaterna, M. H., Kasarskis, A., Uebele, V. N., Turek, F., Renger, J. J. & Winrow, C. J., Dec 1 2011, In : Journal of Neurogenetics. 25, 4, p. 167-181 15 p.

Research output: Contribution to journalArticle

Sleep
Pharmacology
Genes
REM Sleep
Dopamine D5 Receptors