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2020

Repeated sleep disruption in mice leads to persistent shifts in the fecal microbiome and metabolome

Bowers, S. J., Vargas, F., González, A., He, S., Jiang, P., Dorrestein, P. C., Knight, R., Wright, K. P., Lowry, C. A., Fleshner, M., Vitaterna, M. H. & Turek, F. W., 2020, In : PloS one. 15, 2, e0229001.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2019

Distinct ipRGC subpopulations mediate light’s acute and circadian effects on body temperature and sleep

Rupp, A. C., Ren, M., Altimus, C. M., Fernandez, D. C., Richardson, M., Turek, F., Hattar, S. & Schmidt, T. M., Jul 2019, In : eLife. 8, e44358.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

NMDAR activation regulates the daily rhythms of sleep and mood

Burgdorf, J. S., Vitaterna, M. H., Olker, C. J., Song, E. J., Christian, E. P., Sørensen, L., Turek, F. W., Madsen, T. M., Khan, M. A., Kroes, R. A. & Moskal, J. R., Oct 1 2019, In : Sleep. 42, 10, zsz135.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
Open Access
3 Scopus citations

Reproducible changes in the gut microbiome suggest a shift in microbial and host metabolism during spaceflight

Jiang, P., Green, S. J., Chlipala, G. E., Turek, F. W. & Vitaterna, M. H., Aug 9 2019, In : Microbiome. 7, 1, 113.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

The NASA twins study: A multidimensional analysis of a year-long human spaceflight

Garrett-Bakelman, F. E., Darshi, M., Green, S. J., Gur, R. C., Lin, L., Macias, B. R., McKenna, M. J., Meydan, C., Mishra, T., Nasrini, J., Piening, B. D., Rizzardi, L. F., Sharma, K., Siamwala, J. H., Taylor, L., Vitaterna, M. H., Afkarian, M., Afshinnekoo, E., Ahadi, S., Ambati, A. & 62 others, Arya, M., Bezdan, D., Callahan, C. M., Chen, S., Choi, A. M. K., Chlipala, G. E., Contrepois, K., Covington, M., Crucian, B. E., De Vivo, I., Dinges, D. F., Ebert, D. J., Feinberg, J. I., Gandara, J. A., George, K. A., Goutsias, J., Grills, G. S., Hargens, A. R., Heer, M., Hillary, R. P., Hoofnagle, A. N., Hook, V. Y. H., Jenkinson, G., Jiang, P., Keshavarzian, A., Laurie, S. S., Lee-McMullen, B., Lumpkins, S. B., MacKay, M., Maienschein-Cline, M. G., Melnick, A. M., Moore, T. M., Nakahira, K., Patel, H. H., Pietrzyk, R., Rao, V., Saito, R., Salins, D. N., Schilling, J. M., Sears, D. D., Sheridan, C. K., Stenger, M. B., Tryggvadottir, R., Urban, A. E., Vaisar, T., Van Espen, B., Zhang, J., Ziegler, M. G., Zwart, S. R., Charles, J. B., Kundrot, C. E., Scott, G. B. I., Bailey, S. M., Basner, M., Feinberg, A. P., Lee, S. M. C., Mason, C. E., Mignot, E., Rana, B. K., Smith, S. M., Snyder, M. P. & Turek, F. W., 2019, In : Science. 364, 6436, eaau8650.

Research output: Contribution to journalArticle

97 Scopus citations

Trait-like vulnerability of higher-order cognition and ability to maintain wakefulness during combined sleep restriction and circadian misalignment

Sprecher, K. E., Ritchie, H. K., Burke, T. M., Depner, C. M., Smits, A. N., Dorrestein, P. C., Fleshner, M., Knight, R., Lowry, C. A., Turek, F. W., Vitaterna, M. H. & Wright, K. P., Aug 1 2019, In : Sleep. 42, 8, zsz113.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018

Cross-species systems analysis identifies gene networks differentially altered by sleep loss and depression

Scarpa, J. R., Jiang, P., Gao, V. D., Fitzpatrick, K., Millstein, J., Olker, C., Gotter, A., Winrow, C. J., Renger, J. J., Kasarskis, A., Turek, F. W. & Vitaterna, M. H., Jul 25 2018, In : Science Advances. 4, 7, eaat1294.

Research output: Contribution to journalArticle

2 Scopus citations
5 Scopus citations
2016

Altered Body Weight Regulation in CK1ϵ Null and tau Mutant Mice on Regular Chow and High Fat Diets

Zhou, L., Summa, K. C., Olker, C., Vitaterna, M. H. & Turek, F. W., Jan 1 2016, In : Genetics Research International. 2016, 4973242.

Research output: Contribution to journalArticle

3 Scopus citations

Circadian rhythms, metabolism, and chrononutrition in rodents and humans

Johnston, J. D., Ordovás, J. M., Scheer, F. A. & Turek, F. W., Jan 1 2016, In : Advances in Nutrition. 7, 2, p. 399-406 8 p.

Research output: Contribution to journalArticle

56 Scopus citations

Circadian Rhythms in Gastrointestinal Health and Diseases

Bishehsari, F., Levi, F., Turek, F. W. & Keshavarzian, A., Sep 1 2016, In : Gastroenterology. 151, 3, p. e1-e5

Research output: Contribution to journalArticle

17 Scopus citations

Light/dark shifting promotes alcohol-induced colon carcinogenesis: Possible role of intestinal inflammatory milieu and microbiota

Bishehsari, F., Saadalla, A., Khazaie, K., Engen, P. A., Voigt, R. M., Shetuni, B. B., Forsyth, C., Shaikh, M., Vitaterna, M. H., Turek, F. & Keshavarzian, A., Dec 2 2016, In : International journal of molecular sciences. 17, 12, 2017.

Research output: Contribution to journalArticle

24 Scopus citations

Multiple classifier systems for automatic sleep scoring in mice

Gao, V., Turek, F. & Vitaterna, M., May 1 2016, In : Journal of Neuroscience Methods. 264, p. 33-39 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Night workers with circadian misalignment are susceptible to alcohol-induced intestinal hyperpermeability with social drinking

Swanson, G. R., Gorenz, A., Shaikh, M., Desai, V., Kaminsky, T., van Den Berg, J., Murphy, T., Raeisi, S., Fogg, L., Vitaterna, M. H., Forsyth, C., Turek, F., Burgess, H. J. & Keshavarzian, A., Jul 1 2016, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 311, 1, p. G192-G201

Research output: Contribution to journalArticle

27 Scopus citations

Systems Genetic Analyses Highlight a TGFβ-FOXO3 Dependent Striatal Astrocyte Network Conserved across Species and Associated with Stress, Sleep, and Huntington’s Disease

Scarpa, J. R., Jiang, P., Losic, B., Readhead, B., Gao, V. D., Dudley, J. T., Vitaterna, M. H., Turek, F. W. & Kasarskis, A., Jul 2016, In : PLoS genetics. 12, 7, e1006137.

Research output: Contribution to journalArticle

11 Scopus citations

The Circadian Clock Mutation Promotes Intestinal Dysbiosis

Voigt, R. M., Summa, K. C., Forsyth, C. B., Green, S. J., Engen, P., Naqib, A., Vitaterna, M. H., Turek, F. W. & Keshavarzian, A., Feb 1 2016, In : Alcoholism: Clinical and Experimental Research. 40, 2, p. 335-347 13 p.

Research output: Contribution to journalArticle

50 Scopus citations
2015

A Systems Approach Identifies Networks and Genes Linking Sleep and Stress: Implications for Neuropsychiatric Disorders

Jiang, P., Scarpa, J. R., Fitzpatrick, K., Losic, B., Gao, V. D., Hao, K., Summa, K. C., Yang, H. S., Zhang, B., Allada, R., Vitaterna, M. H., Turek, F. W. & Kasarskis, A., Jan 1 2015, In : Cell reports. 11, 5, p. 835-848 14 p.

Research output: Contribution to journalArticle

21 Scopus citations

Chronic Alcohol Exposure and the Circadian Clock Mutation Exert Tissue-Specific Effects on Gene Expression in Mouse Hippocampus, Liver, and Proximal Colon

Summa, K. C., Jiang, P., Fitzpatrick, K., Voigt, R. M., Bowers, S. J., Forsyth, C. B., Vitaterna, M. H., Keshavarzian, A. & Turek, F. W., Oct 2015, In : Alcoholism: Clinical and Experimental Research. 39, 10, p. 1917-1929 13 p.

Research output: Contribution to journalArticle

9 Scopus citations

Environmental Disruption of Circadian Rhythm Predisposes Mice to Osteoarthritis-Like Changes in Knee Joint

Kc, R., Li, X., Voigt, R. M., Ellman, M. B., Summa, K. C., Vitaterna, M. H., Keshavarizian, A., Turek, F. W., Meng, Q. J., Stein, G. S., van Wijnen, A. J., Chen, D., Forsyth, C. B. & Im, H. J., Sep 1 2015, In : Journal of Cellular Physiology. 230, 9, p. 2174-2183 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

Induction of osteoarthritis-like pathologic changes by chronic alcohol consumption in an experimental mouse model

Kc, R., Voigt, R., Li, X., Forsyth, C. B., Ellman, M. B., Summa, K. C., Turek, F. W., Keshavarzian, A., Kim, J. S. & Im, H. J., Jun 1 2015, In : Arthritis and Rheumatology. 67, 6, p. 1678-1680 3 p.

Research output: Contribution to journalArticle

6 Scopus citations

Metabolic effects of bariatric surgery in mouse models of circadian disruption

Arble, D. M., Sandoval, D. A., Turek, F. W., Woods, S. C. & Seeley, R. J., Aug 6 2015, In : International Journal of Obesity. 39, 8, p. 1310-1318 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

New approach for analyzing self-reporting of insomnia symptoms reveals a high rate of comorbid insomnia across a wide spectrum of chronic diseases

Katic, B., Heywood, J., Turek, F. W., Chiauzzi, E., Vaughan, T. E., Simacek, K., Wicks, P., Jain, S., Winrow, C. & Renger, J. J., Nov 1 2015, In : Sleep Medicine. 16, 11, p. 1332-1341 10 p., 2866.

Research output: Contribution to journalArticle

11 Scopus citations

Nocturnal eczema: Review of sleep and circadian rhythms in children with atopic dermatitis and future research directions

Fishbein, A. B., Vitaterna, O., Haugh, I. M., Bavishi, A. A., Zee, P. C., Turek, F. W., Sheldon, S. H., Silverberg, J. I. & Paller, A. S., Nov 1 2015, In : Journal of Allergy and Clinical Immunology. 136, 5, p. 1170-1177 8 p.

Research output: Contribution to journalArticle

50 Scopus citations

Osteoarthritis-like pathologic changes in the knee joint induced by environmental disruption of circadian rhythms is potentiated by a high-fat diet

Kc, R., Li, X., Forsyth, C. B., Voigt, R. M., Summa, K. C., Vitaterna, M. H., Tryniszewska, B., Keshavarzian, A., Turek, F. W., Meng, Q. J. & Im, H. J., Nov 20 2015, In : Scientific reports. 5, 16896.

Research output: Contribution to journalArticle

13 Scopus citations

Selective pharmacological blockade of the 5-HT7 receptor attenuates light and 8-OH-DPAT induced phase shifts of mouse circadian wheel running activity

Shelton, J., Yun, S., Olson, S. L., Turek, F., Bonaventure, P., Dvorak, C., Lovenberg, T. & Dugovic, C., Jan 15 2015, In : Frontiers in Behavioral Neuroscience. 8, JAN, 453.

Research output: Contribution to journalArticle

9 Scopus citations

The clocks within Us

Summa, K. C. & Turek, F. W., Jan 1 2015, In : Scientific American. 312, 2, p. 51-55 5 p.

Research output: Contribution to journalArticle

4 Scopus citations
2014

Chronobiology and obesity: Interactions between circadian rhythms and energy regulation

Summa, K. C. & Turek, F. W., Jan 1 2014, In : Advances in Nutrition. 5, 3, p. 312S-319S

Research output: Contribution to journalArticle

36 Scopus citations

Circadian disorganization alters intestinal microbiota

Voigt, R. M., Forsyth, C. B., Green, S. J., Mutlu, E., Engen, P., Vitaterna, M. H., Turek, F. W. & Keshavarzian, A., May 21 2014, In : PloS one. 9, 5, e97500.

Research output: Contribution to journalArticle

159 Scopus citations

Circadian melatonin rhythm and excessive daytime sleepiness in Parkinson disease

Videnovic, A., Noble, C., Reid, K. J., Peng, J., Turek, F. W., Marconi, A., Rademaker, A. W., Simuni, T., Zadikoff, C. & Zee, P. C., Apr 2014, In : JAMA Neurology. 71, 4, p. 463-469 7 p.

Research output: Contribution to journalArticle

142 Scopus citations

The circadian clock gene Csnk1e regulates rapid eye movement sleep amount, and nonrapid eye movement sleep architecture in mice

Zhou, L., Bryant, C. D., Loudon, A., Palmer, A. A., Vitaterna, M. H. & Turek, F. W., Apr 1 2014, In : Sleep. 37, 4, p. 785-793 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Validation of video motion-detection scoring of forced swim test in mice

Gao, V., Vitaterna, M. H. & Turek, F. W., Sep 30 2014, In : Journal of Neuroscience Methods. 235, p. 59-64 6 p.

Research output: Contribution to journalArticle

5 Scopus citations
2013

Animal care practices in experiments on biological rhythms and sleep: Report of the Joint Task Force of the Society for Research on Biological Rhythms and the Sleep Research Society

Bittman, E. L., Kilduff, T. S., Kriegsfeld, L. J., Szymusiak, R., Toth, L. A. & Turek, F. W., Jul 1 2013, In : Journal of the American Association for Laboratory Animal Science. 52, 4, p. 437-443 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Circadian control of mouse heart rate and blood pressure by the suprachiasmatic nuclei: Behavioral effects are more significant than direct outputs

Sheward, W. J., Naylor, E., Knowles-Barley, S., Armstrong, J. D., Brooker, G. A., Seckl, J. R., Turek, F. W., Holmes, M. C., Zee, P. C. & Harmar, A. J., Feb 8 2013, In : PloS one. 5, 3, e9783.

Research output: Contribution to journalArticle

53 Scopus citations

Disruption of the Circadian Clock in Mice Increases Intestinal Permeability and Promotes Alcohol-Induced Hepatic Pathology and Inflammation

Summa, K. C., Voigt, R. M., Forsyth, C. B., Shaikh, M., Cavanaugh, K., Tang, Y., Vitaterna, M. H., Song, S., Turek, F. W. & Keshavarzian, A., Jun 18 2013, In : PloS one. 8, 6, e67102.

Research output: Contribution to journalArticle

112 Scopus citations

Role for intestinal CYP2E1 in alcohol-induced circadian gene-mediated intestinal hyperpermeability

Forsyth, C. B., Voigt, R. M., Shaikh, M., Tang, Y., Cederbaum, A. I., Turek, F. W. & Keshavarzian, A., Jul 15 2013, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 305, 2, p. G185-G195

Research output: Contribution to journalArticle

34 Scopus citations
2012

Altered sleep and affect in the neurotensin receptor 1 knockout mouse

Fitzpatrick, K., Winrow, C. J., Gotter, A. L., Millstein, J., Arbuzova, J., Brunner, J., Kasarskis, A., Vitaterna, M. H., Renger, J. J. & Turek, F. W., Jul 1 2012, In : Sleep. 35, 7, p. 949-956 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

Csnk1e is a genetic regulator of sensitivity to psychostimulants and opioids

Bryant, C. D., Parker, C. C., Zhou, L., Olker, C., Chandrasekaran, R. Y., Wager, T. T., Bolivar, V. J., Loudon, A. S., Vitaterna, M. H., Turek, F. W. & Palmer, A. A., Mar 1 2012, In : Neuropsychopharmacology. 37, 4, p. 1026-1035 10 p.

Research output: Contribution to journalArticle

36 Scopus citations

Environmental perturbation of the Circadian clock disrupts pregnancy in the mouse

Summa, K. C., Vitaterna, M. H. & Turek, F. W., May 23 2012, In : PloS one. 7, 5, e37668.

Research output: Contribution to journalArticle

53 Scopus citations

High-resolution mapping of a novel genetic locus regulating voluntary physical activity in mice

Yang, H. S., Shimomura, K., Vitaterna, M. H. & Turek, F. W., Feb 1 2012, In : Genes, Brain and Behavior. 11, 1, p. 113-124 12 p.

Research output: Contribution to journalArticle

11 Scopus citations
2011

Identification of causal genes, networks, and transcriptional regulators of REM sleep and wake

Millstein, J., Winrow, C. J., Kasarskis, A., Owens, J. R., Zhou, L., Summa, K. C., Fitzpatrick, K., Zhang, B., Vitaterna, M. H., Schadt, E. E., Renger, J. J. & Turek, F. W., Nov 1 2011, In : Sleep. 34, 11, p. 1469-1477 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Molecular neurobiology of circadian rhythms

Turek, F. W. & Vitaterna, M. H., Jan 1 2011, In : Handbook of Clinical Neurology. 99, C, p. 951-961 11 p.

Research output: Contribution to journalArticle

2 Scopus citations
5 Scopus citations

Pharmacological validation of candidate causal sleep genes identified in an N2 cross

Brunner, J. I., Gotter, A. L., Millstein, J., Garson, S., Binns, J., Fox, S. V., Savitz, A. T., Yang, H. S., Fitzpatrick, K., Zhou, L., Owens, J. R., Webber, A. L., Vitaterna, M. H., Kasarskis, A., Uebele, V. N., Turek, F., Renger, J. J. & Winrow, C. J., Dec 1 2011, In : Journal of Neurogenetics. 25, 4, p. 167-181 15 p.

Research output: Contribution to journalArticle

5 Scopus citations

Rhythmic leptin is required for weight gain from circadian desynchronized feeding in the mouse

Arble, D. M., Vitaterna, M. H. & Turek, F. W., Sep 19 2011, In : PloS one. 6, 9, e25079.

Research output: Contribution to journalArticle

29 Scopus citations

Role of Intestinal Circadian Genes in Alcohol-Induced Gut Leakiness

Swanson, G., Forsyth, C. B., Tang, Y., Shaikh, M., Zhang, L., Turek, F. W. & Keshavarzian, A., Jul 1 2011, In : Alcoholism: Clinical and Experimental Research. 35, 7, p. 1305-1314 10 p.

Research output: Contribution to journalArticle

45 Scopus citations
2009

Circadian timing of food intake contributes to weight gain

Arble, D. M., Bass, J., Laposky, A. D., Vitaterna, M. H. & Turek, F. W., Nov 1 2009, In : Obesity. 17, 11, p. 2100-2102 3 p.

Research output: Contribution to journalArticle

514 Scopus citations

Genetic analysis of daily physical activity using a mouse chromosome substitution strain

Yang, H. S., Vitaterna, M. H., Laposky, A. D., Shimomura, K. & Turek, F. W., Sep 1 2009, In : Physiological Genomics. 39, 1, p. 47-55 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Identification of genetic loci involved in diabetes using a rat model of depression

Solberg Woods, L. C., Ahmadiyeh, N., Baum, A., Shimomura, K., Li, Q., Steiner, D. F., Turek, F. W., Takahashi, J. S., Churchill, G. A. & Redei, E., Aug 1 2009, In : Mammalian Genome. 20, 8, p. 486-497 12 p.

Research output: Contribution to journalArticle

9 Scopus citations
39 Scopus citations