Frederick D Lewis

  • 11991 Citations
1967 …2018
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Personal profile

Research Interests

Understanding the relationship between the unique structure of DNA and its interaction with light. The foundation for the research is the design, synthesis, and characterization of short stable DNA base pair domains.

Education/Academic qualification

PhD, University of Rochester

… → 1968

BA, Amherst College

… → 1965

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  • 4 Similar Profiles
DNA Engineering & Materials Science
Stilbenes Chemical Compounds
Photochemical reactions Chemical Compounds
Fluorescence Chemical Compounds
deoxyribonucleic acid Physics & Astronomy
Excited states Chemical Compounds
Electrons Chemical Compounds
Amines Chemical Compounds

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Grants 2004 2018

Research Output 1967 2018

Fluorescent excimers and exciplexes of the purine base derivative 8-phenylethynyl-guanine in DNA hairpins

Brown, K. E., Singh, A. P. N., Wu, Y. L., Ma, L., Mishra, A. K., Phelan, B. T., Young, R. M., Lewis, F. D. & Wasielewski, M. R., Jan 1 2018, In : Faraday Discussions. 207, p. 217-232 16 p.

Research output: Contribution to journalArticle

purines
guanines
Guanine
excimers
Excited states
3 Citations (Scopus)

Photocrosslinking between nucleic acids and proteins: General discussion

Bhat, V., Cogdell, R., Crespo-Hernández, C. E., Datta, A., De, A., Haacke, S., Helliwell, J., Improta, R., Joseph, J., Karsili, T., Kohler, B., Krishnan, R., Mahil, L. M., Lewis, F., Mandal, I., Markovitsi, D., Mishra, P. P., Paul, S., Periyasamy, G., Pradeepkumar, P. I. & 12 others, Roy Chowdhury, P., Sarangi, M., Sasikumar, D., Schapiro, I., Schertler, G. F. X., Schlichting, I., Segarra-Martí, J., Swaminathan, R., Vishnu, V., Van Grondelle, R., Varghese, R. & Venkatramani, R., Jan 1 2018, In : Faraday Discussions. 207, p. 283-306 24 p.

Research output: Contribution to journalComment/debate

Photochemical Processes
Cross-Linking Reagents
Nucleic Acids
DNA
Proteins
5 Citations (Scopus)

Tracking Photoinduced Charge Separation in DNA: From Start to Finish

Lewis, F. D., Young, R. M. & Wasielewski, M. R., Aug 21 2018, In : Accounts of chemical research. 51, 8, p. 1746-1754 9 p.

Research output: Contribution to journalArticle

Chromophores
DNA
Guanine
Charge injection
Free energy
3 Citations (Scopus)

Dynamics of Charge Injection and Charge Recombination in DNA Mini-Hairpins

Mishra, A. K., Harris, M. A., Young, R. M., Wasielewski, M. R. & Lewis, F. D., Jul 27 2017, In : Journal of Physical Chemistry B. 121, 29, p. 7042-7047 6 p.

Research output: Contribution to journalArticle

Charge injection
Base Pairing
Genetic Recombination
DNA
deoxyribonucleic acid
15 Citations (Scopus)

Efficient charge transport via DNA G-quadruplexes

Thazhathveetil, A. K., Harris, M. A., Young, R. M., Wasielewski, M. R. & Lewis, F. D., Feb 8 2017, In : Journal of the American Chemical Society. 139, 5, p. 1730-1733 4 p.

Research output: Contribution to journalArticle

G-Quadruplexes
Charge transfer
DNA
Hole traps
Absorption spectroscopy