Gabriella Sekerkova

  • 1381 Citations
1993 …2020
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Personal profile

Research Interests

My research is focused on sensory neuroscience with special interest in espins, a novel family of multifunctional actin-bundling proteins. These proteins are present at high concentration in the parallel actin bundle of hair cell stereocilia, in the microvilli of taste receptor cells, solitary chemoreceptor cells, vomeronasal sensory neurons and Merkel cells. Mutations in espin gene cause deafness and vestibular dysfunction in mice and humans. I am investigating the effect of these mutations on the sensory systems during development and adulthood.

Training Experience

2001Postdoctoral Fellowship, Northwestern University Feinberg School of Medicine

Education/Academic qualification

MVDr, CSc, University of Veterinary Med, Slovakia

… → 1987

Research interests

  • Brain and Nervous System
  • Cell Imaging
  • Cytoskeleton
  • Developmental Neurobiology
  • Hearing
  • Microscopy
  • Neurobiology
  • Neuroscience

Fingerprint Dive into the research topics where Gabriella Sekerkova is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 8 Similar Profiles
Olfactory Bulb Medicine & Life Sciences
Actins Medicine & Life Sciences
Stereocilia Medicine & Life Sciences
Cerebellum Medicine & Life Sciences
Neurons Medicine & Life Sciences
Microvilli Medicine & Life Sciences
Purkinje Cells Medicine & Life Sciences
Cytoskeletal Proteins Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2008 2020

Research Output 1993 2016

74 Citations (Scopus)

Consensus Paper: Cerebellar Development

Leto, K., Arancillo, M., Becker, E. B. E., Buffo, A., Chiang, C., Ding, B., Dobyns, W. B., Dusart, I., Haldipur, P., Hatten, M. E., Hoshino, M., Joyner, A. L., Kano, M., Kilpatrick, D. L., Koibuchi, N., Marino, S., Martinez, S., Millen, K. J., Millner, T. O., Miyata, T. & 9 others, Parmigiani, E., Schilling, K., Sekerkova, G., Sillitoe, R. V., Sotelo, C., Uesaka, N., Wefers, A., Wingate, R. J. T. & Hawkes, R., Dec 1 2016, In : Cerebellum. 15, 6, p. 789-828 40 p.

Research output: Contribution to journalReview article

Cerebellum

Unipolar brush cells

Martina, M. & Sekerkova, G., Jan 1 2016, Essentials of Cerebellum and Cerebellar Disorders: A Primer for Graduate Students. Springer International Publishing, p. 213-218 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Brushes
cells
Cerebellar Cortex
cerebellum
Cerebellum
15 Citations (Scopus)

Absence of alsin function leads to corticospinal motor neuron vulnerability via novel disease mechanisms

Gautam, M., Jara, J. H., Sekerkova, G., Yasvoina, M. V., Martina, M. & Özdinler, P. H., Aug 17 2015, In : Human molecular genetics. 25, 6, p. 1074-1087 14 p.

Research output: Contribution to journalArticle

Motor Neurons
Knockout Mice
Hereditary Spastic Paraplegia
Pathology
Pons
3 Citations (Scopus)
20th Century History
Neuroanatomy
Cerebellar Cortex
Mammals
Neurons
4 Citations (Scopus)

The Spontaneous Ataxic Mouse Mutant Tippy is Characterized by a Novel Purkinje Cell Morphogenesis and Degeneration Phenotype

Shih, E. K., Sekerkova, G., Ohtsuki, G., Aldinger, K. A., Chizhikov, V. V., Hansel, C., Mugnaini, E. & Millen, K. J., Jun 26 2015, In : Cerebellum. 14, 3, p. 292-307 16 p., 640.

Research output: Contribution to journalArticle

Purkinje Cells
Morphogenesis
Phenotype
Mutation
Neurologic Mutant Mice