• 403 Citations
20012024
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Fingerprint Dive into the research topics where Gary E Schiltz is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 3 Similar Profiles
Neoplasms Medicine & Life Sciences
Ligands Medicine & Life Sciences
HIV Protease Inhibitors Medicine & Life Sciences
Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels Chemical Compounds
Assays Chemical Compounds
Protease Inhibitors Chemical Compounds
Therapeutics Medicine & Life Sciences
Scaffolds Chemical Compounds

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Grants 2011 2024

Neuropharmacology
Pharmaceutical Preparations
Ligands
Technology
Neurobiology
Kidney
Kidney Diseases
Research Personnel
Therapeutics
Nanomedicine
Antidepressive Agents
High-Throughput Screening Assays
Manuscripts
Organized Financing
Research
CXC Chemokines
MAP Kinase Signaling System
Chemokine Receptors
Chemokines
Prostatic Neoplasms

Research Output 2001 2019

  • 403 Citations
  • 25 Article
  • 2 Review article
  • 1 Chapter

A novel strategy to block mitotic progression for targeted therapy

Chi, J. J., Li, H., Zhou, Z., Izquierdo-Ferrer, J., Xue, Y., Wavelet, C. M., Schiltz, G. E., Zhang, B., Cristofanilli, M., Lu, X., Bahar, I. & Wan, Y., Nov 2019, In : EBioMedicine. 49, p. 40-54 15 p.

Research output: Contribution to journalArticle

Open Access
Degradation
Tumors
Cells
Neoplasms
Breast Neoplasms

Development of Tetrahydroindazole-Based Potent and Selective Sigma-2 Receptor Ligands

Iyamu, I. D., Lv, W., Malik, N., Mishra, R. K. & Schiltz, G. E., Jul 3 2019, In : ChemMedChem. 14, 13, p. 1248-1256 9 p.

Research output: Contribution to journalArticle

Drug Discovery
Ligands
Central Nervous System Diseases
Neurology
Solubility
2 Citations (Scopus)

Discovery of a novel class of potent and selective tetrahydroindazole-based sigma-1 receptor ligands

Iyamu, I. D., Lv, W., Malik, N., Mishra, R. K. & Schiltz, G. E., May 1 2019, In : Bioorganic and Medicinal Chemistry. 27, 9, p. 1824-1835 12 p.

Research output: Contribution to journalArticle

Protein Transport
Ligands
Molecular modeling
Central Nervous System Diseases
Structure-Activity Relationship

Discovery of novel Mnk inhibitors using mutation-based induced-fit virtual high-throughput screening

Mishra, R. K., Clutter, M. R., Blyth, G. T., Kosciuczuk, E. M., Blackburn, A. Z., Beauchamp, E. M., Schiltz, G. E. & Platanias, L. C., Oct 1 2019, In : Chemical Biology and Drug Design. 94, 4, p. 1813-1823 11 p.

Research output: Contribution to journalArticle

Screening
Phosphotransferases
Throughput
Acute Myeloid Leukemia
Mutation

Modeling MEK4 Kinase Inhibitors through Perturbed Electrostatic Potential (ESP) Charges

Mishra, R. K., Deibler, K. K., Clutter, M. R., Vagadia, P. P., O'Connor, M., Schiltz, G. E., Bergan, R. & Scheidt, K. A., Jan 1 2019, (Accepted/In press) In : Journal of Chemical Information and Modeling.

Research output: Contribution to journalArticle

Electrostatics
activity structure
Phosphotransferases
non-alignment
predictive model