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Gary E Schiltz

  • 437 Citations
20012024

Research output per year

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Grants

Development of Novel MNK Inhibitors for Treating Glioblastoma

Clutter, M., Eckerdt, F. D., Horbinski, C. M., James, C. D., Mishra, R. K., Platanias, L. C. & Schiltz, G. E.

National Institute of Neurological Disorders and Stroke

9/1/19 → 6/30/24

Project: Research project

    • DART2.0: comprehensive cell type-specific behavioral neuropharmacology

    Schiltz, G. E.

    Duke University, National Institute of Mental Health

    9/14/18 → 9/13/21

    Project: Research project

    • Subproject for SP0046885 Luo Core B

    Jin, J., Kandela, I., Luo, X., Mathew, J., Schiltz, G. E., Scott, E. A., Vanoye, C. G. & Wertheim, J. A.

    National Institute of Diabetes, Digestive and Kidney Diseases

    8/1/18 → 7/31/23

    Project: Research project

    • Targeting chemokine signaling and MAPK/ERK pathway in advanced prostate cancer

    Yu, J., Cristofanilli, M., Hussain, M., Miller, R. J., Schiltz, G. E., Yang, X. J., Zhang, B. & Zhao, C.

    Prostate Cancer Foundation

    12/31/17 → 12/31/20

    Project: Research project

    • Targeting EZH2 in castration-resistant prostate cancer

    Mishra, R. K. & Schiltz, G. E.

    U.S. Army Medical Research and Materiel Command

    8/1/17 → 7/31/20

    Project: Research project

    • Research Output

    • 437 Citations
    • 25 Article
    • 2 Review article
    • 1 Chapter

    A novel strategy to block mitotic progression for targeted therapy

    Chi, J. J., Li, H., Zhou, Z., Izquierdo-Ferrer, J., Xue, Y., Wavelet, C. M., Schiltz, G. E., Zhang, B., Cristofanilli, M., Lu, X., Bahar, I. & Wan, Y., Nov 2019, In : EBioMedicine. 49, p. 40-54 15 p.

    Research output: Contribution to journal › Article

    Open Access
    • 2 Scopus citations

    Development of Tetrahydroindazole-Based Potent and Selective Sigma-2 Receptor Ligands

    Iyamu, I. D., Lv, W., Malik, N., Mishra, R. K. & Schiltz, G. E., Jul 3 2019, In : ChemMedChem. 14, 13, p. 1248-1256 9 p.

    Research output: Contribution to journal › Article

    • Discovery of a novel class of potent and selective tetrahydroindazole-based sigma-1 receptor ligands

    Iyamu, I. D., Lv, W., Malik, N., Mishra, R. K. & Schiltz, G. E., May 1 2019, In : Bioorganic and Medicinal Chemistry. 27, 9, p. 1824-1835 12 p.

    Research output: Contribution to journal › Article

    • 2 Scopus citations

    Discovery of novel Mnk inhibitors using mutation-based induced-fit virtual high-throughput screening

    Mishra, R. K., Clutter, M. R., Blyth, G. T., Kosciuczuk, E. M., Blackburn, A. Z., Beauchamp, E. M., Schiltz, G. E. & Platanias, L. C., Oct 1 2019, In : Chemical Biology and Drug Design. 94, 4, p. 1813-1823 11 p.

    Research output: Contribution to journal › Article

    • Modeling MEK4 Kinase Inhibitors through Perturbed Electrostatic Potential (ESP) Charges

    Mishra, R. K., Deibler, K. K., Clutter, M. R., Vagadia, P. P., O'Connor, M., Schiltz, G. E., Bergan, R. & Scheidt, K. A., Jan 1 2019, (Accepted/In press) In : Journal of Chemical Information and Modeling.

    Research output: Contribution to journal › Article