Grants per year
Personal profile
Research Interests
My research is focused on two general areas: radiobiology and bionanotechnology. Work in radiobiology includes studies of the molecular biology of radiation responses, particularly radiation toxicities, radiation effects, dose-, dose-rate, and radiation quality issues and other general areas of radiobiology. In addition, my laboratory houses the tissues and data from mojority of the radiobilogical experiments conducted in US between 1950-1990's (http://janus.northwestern.edu). In addition to sharing these data and materials with the radiobiological community, my group is investigating the archive as well; we are applying new statistical approaches on old datasets and new experimental approaches for investigation of formalin fixed and paraffin embedded materials. Work with micro-RNA microarrays, and use of X-ray fluorescence microscopy for histopathological analysis fall into this research. Work in bionanotechnology includes development and investigation of multifunctional nanoconstructs, increasing contrast for biomedical imaging (MRI and CT), enabling delivery of small molecules (such as chemotherapeutic drugs, flavonoids etc.) and producing cytotoxic reactive oxygen species to fortify effect of radiotherapy.
Training Experience
1983 | Postdoctoral Fellowship, Mayo Medical School |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Microbiology, Med Coll OH-Toledo
… → 1980
Research interests keywords
- Biotechnology
- Nanotechnology
- Radiation Oncology
- Radiology
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Collaborations and top research areas from the last five years
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Single Cell level elemental signatures of low dose radiation exposures in mammalian model systems
Woloschak, G. E. (PD/PI), Gursel, D. B. (Co-Investigator), Horbinski, C. M. (Co-Investigator), Paunesku, T. (Co-Investigator), Stock, S. R. (Co-Investigator), Sun, Z. (Co-Investigator) & Wai, C. M. (Co-Investigator)
9/1/24 → 8/31/27
Project: Research project
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Dosimetry and health effects of internal radionuclides
Woloschak, G. E. (PD/PI) & Woloschak, G. E. (PD/PI)
National Institute of Allergy and Infectious Diseases
8/15/23 → 7/31/25
Project: Research project
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CCSG Program Leadership
Arispe, L. (Other), Backman, V. (Other), Godley, L. A. (Other), Hitsman, B. L. (Other), Khan, S. A. (Other), Matei, D. E. (Other), Munshi, H. G. (Other), Peter, M. E. (Other), Rini, C. (Other), Shilatifard, A. (Other), Simon, M. A. (Other), Stupp, R. (Other), Wignall, S. (Other), Woloschak, G. E. (Other), Yanez, B. R. (Other) & Zhang, B. (Other)
8/1/23 → 7/31/25
Project: Research project
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Graduate Research Fellowship Program (GRFP)
Woloschak, G. E. (PD/PI) & Woloschak, G. E. (PD/PI)
9/1/22 → 8/31/27
Project: Research project
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Comparison of Acute and Protracted Gamma Irradiation Effects During Perinatal Development in Beagle Dogs
Sreetharan, S., Puukila, S., Lalonde, C., Pirkkanen, J., Woloschak, G. E., Paunesku, T., Brooks, A. L., Mcneill, F. E., Thome, C., Boreham, D. R., Lees, S. J., Tharmalingam, S. & Tai, T. C., Jan 24 2025, In: Radiation Research. 203, 2, p. 73-82 10 p.Research output: Contribution to journal › Article › peer-review
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X-ray Fluorescence Microscopy to Develop Elemental Classifiers and Investigate Elemental Signatures in BALB/c Mouse Intestine a Week after Exposure to 8 Gy of Gamma Rays
Smith, A., Dobinda, K., Chen, S., Zieba, P., Paunesku, T., Sun, Z. & Woloschak, G. E., Oct 2024, In: International journal of molecular sciences. 25, 19, 10256.Research output: Contribution to journal › Article › peer-review
Open Access -
Gene Expression and Early Radiation Response of Two Distinct Neuroblastoma Cell Lines
Ritner, C., Popovic, J., Abouzeid, A., Li, Y., Paunesku, T., Papineni, R. & Woloschak, G., 2023, (Accepted/In press) In: Oncology (United States).Research output: Contribution to journal › Article › peer-review
Open Access -
Lessons learned in the practice of community-based participatory research with community partner collaboration in study design and implementation: the community scientist model
Morrell, M. A., Willis, T. R., Brown, D. R., O’Brian, C. A., Post, S. L., Woloschak, G. E., Bonini, M. G., Paunesku, T., Popovic, J., Manning, T. M., Henley, C., Girotti, J., Rogers, R., Velásquez, C., López, J., Glenn, J. & Simon, M. A., Jul 2023, In: Cancer Causes and Control. 34, 7, p. 621-624 4 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Proof of principle study: synchrotron X-ray fluorescence microscopy for identification of previously radioactive microparticles and elemental mapping of FFPE tissues
Copeland-Hardin, L., Paunesku, T., Murley, J. S., Crentsil, J., Antipova, O., Li, L. X., Maxey, E., Jin, Q., Hooper, D., Lai, B., Chen, S. & Woloschak, G. E., Dec 2023, In: Scientific reports. 13, 1, 7806.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations
Datasets
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Additional file 2 of Development of Fe3O4 core–TiO2 shell nanocomposites and nanoconjugates as a foundation for neuroblastoma radiosensitization
Liu, W. (Creator), Mirzoeva, S. (Creator), Yuan, Y. (Creator), Deng, J. (Creator), Chen, S. (Creator), Lai, B. (Creator), Vogt, S. (Creator), Shah, K. (Creator), Shroff, R. (Creator), Bleher, R. (Creator), Jin, Q. (Creator), Vo, N. (Creator), Bazak, R. (Creator), Ritner, C. (Creator), Gutionov, S. (Creator), Raha, S. (Creator), Sedlmair, J. (Creator), Hirschmugl, C. (Creator), Jacobsen, C. (Creator), Paunesku, T. (Creator), Kalapurkal, J. (Creator), Woloschak, G. E. (Creator), Blaud, A. (Contributor) & Almeida, A. (Contributor), figshare, 2021
DOI: 10.6084/m9.figshare.14600521, https://springernature.figshare.com/articles/media/Additional_file_2_of_Development_of_Fe3O4_core_TiO2_shell_nanocomposites_and_nanoconjugates_as_a_foundation_for_neuroblastoma_radiosensitization/14600521
Dataset
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Supplementary Material for: Gene expression and early radiation response of two distinct neuroblastoma cell lines
Ritner, C. (Contributor), Popovic, J. (Contributor), Abouzeid, A. (Contributor), Li, Y. (Contributor), Paunesku, T. (Contributor), Papineni, R. (Contributor) & Woloschak, G. (Contributor), Karger Publishers, 2023
DOI: 10.6084/m9.figshare.23254802.v1, https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Gene_expression_and_early_radiation_response_of_two_distinct_neuroblastoma_cell_lines/23254802/1
Dataset
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Development of Fe3O4 core–TiO2 shell nanocomposites and nanoconjugates as a foundation for neuroblastoma radiosensitization
Liu, W. (Creator), Mirzoeva, S. (Creator), Yuan, Y. (Creator), Deng, J. (Creator), Chen, S. (Creator), Lai, B. (Creator), Vogt, S. (Creator), Shah, K. (Creator), Shroff, R. (Creator), Bleher, R. (Creator), Jin, Q. (Creator), Vo, N. (Creator), Bazak, R. (Creator), Ritner, C. (Creator), Gutionov, S. (Creator), Raha, S. (Creator), Sedlmair, J. (Creator), Hirschmugl, C. (Creator), Jacobsen, C. (Creator), Paunesku, T. (Creator), Kalapurkal, J. (Creator) & Woloschak, G. E. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.c.5425456, https://springernature.figshare.com/collections/Development_of_Fe3O4_core_TiO2_shell_nanocomposites_and_nanoconjugates_as_a_foundation_for_neuroblastoma_radiosensitization/5425456
Dataset