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Gayle E Woloschak

  • 4432 Citations
1983 …2023

Research output per year

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Personal profile

Research Interests

My research is focused on two general areas: radiobiology and bionanotechnology. Work in radiobiology includes studies of the molecular biology of radiation responses, particularly radiation toxicities, radiation effects, dose-, dose-rate, and radiation quality issues and other general areas of radiobiology. In addition, my laboratory houses the tissues and data from mojority of the radiobilogical experiments conducted in US between 1950-1990's (http://janus.northwestern.edu). In addition to sharing these data and materials with the radiobiological community, my group is investigating the archive as well; we are applying new statistical approaches on old datasets and new experimental approaches for investigation of formalin fixed and paraffin embedded materials. Work with micro-RNA microarrays, and use of X-ray fluorescence microscopy for histopathological analysis fall into this research. Work in bionanotechnology includes development and investigation of multifunctional nanoconstructs, increasing contrast for biomedical imaging (MRI and CT), enabling delivery of small molecules (such as chemotherapeutic drugs, flavonoids etc.) and producing cytotoxic reactive oxygen species to fortify effect of radiotherapy.

Training Experience

1983Postdoctoral Fellowship, Mayo Medical School

Education/Academic qualification

PhD, Med Coll OH-Toledo

… → 1980

Research interests

  • Biotechnology
  • Nanotechnology
  • Radiation Oncology
  • Radiology

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Grants

The Robert H. Lurie Comprehensive Cancer Center

Agulnik, M., Awatramani, R., Backman, V., Benson III, A. B., Carthew, R. W., Cella, D., Chakravarti, D., Chandel, N., Crispino, J. D., Cristofanilli, M., Eklund, E. A., Frankfurt, O., Gordon, L. I., Green, K. J., Hahn, E. A., Horbinski, C. M., Horvath, C. M., Hussain, M., James, C. D., Kelleher, N. L., Khan, S. A., LaBonne, C., Larson, A. C., Matei, D. E., Meade, T. J., Mondragon, A., Mrksich, M., Munshi, H. G., Murphy, A. B., Penedo, F. J., Perlman, H. R., Peter, M. E., Platanias, L. C., Rademaker, A. W., Rappoport, J. Z., Rosenzweig, A. C., Scheidt, K. A., Simon, M. A., Sosman, J. A., Spring, B., Wei, J., Weiss, E. L. & Woloschak, G. E.

National Cancer Institute

8/10/18 → 7/31/23

Project: Research project

    • Radiation induced cancer risk reduction as a function of dose protraction: interspecies comparison

    Paunesku, T., Rademaker, A. W. & Woloschak, G. E.

    National Cancer Institute

    8/16/17 → 7/31/22

    Project: Research project

    • Subproject for Woloschak and Paunesku for Cryo ptychography combined with x-ray fluorescence analysis of metals in cells

    Paunesku, T. & Woloschak, G. E.

    National Institute of General Medical Sciences

    4/1/17 → 3/31/21

    Project: Research project

    • Cryo ptychography combined with x-ray fluorescence analysis of metals in cells

    Jacobsen, C., Paunesku, T. & Woloschak, G. E.

    National Institute of General Medical Sciences

    4/1/17 → 3/31/21

    Project: Research project

    • Supplement for Cancer Nanotechnology Training Program

    Woloschak, G. E.

    National Cancer Institute

    9/1/15 → 8/31/20

    Project: Research project

    • Research Output

    Insights into platinum-induced peripheral neuropathy-current perspective

    Lazic, A., Popović, J., Paunesku, T., Woloschak, G. E. & Stevanović, M., Sep 1 2020, In : Neural Regeneration Research. 15, 9, p. 1623-1630 8 p.

    Research output: Contribution to journal › Review article

    Open Access

    • Elemental Zn and its Binding Protein Zinc-α2-Glycoprotein are Elevated in HPV-Positive Oropharyngeal Squamous Cell Carcinoma

    Poropatich, K., Paunesku, T., Zander, A., Wray, B., Schipma, M., Dalal, P., Agulnik, M., Chen, S., Lai, B., Antipova, O., Maxey, E., Brown, K., Wanzer, M. B., Gursel, D., Fan, H., Rademaker, A., Woloschak, G. E. & Mittal, B. B., Dec 1 2019, In : Scientific reports. 9, 1, 16965.

    Research output: Contribution to journal › Article

    Open Access

    • Funding for radiation research: past, present and future

    Cho, K., Imaoka, T., Klokov, D., Paunesku, T., Salomaa, S., Birschwilks, M., Bouffler, S., Brooks, A. L., Hei, T. K., Iwasaki, T., Ono, T., Sakai, K., Wojcik, A., Woloschak, G. E., Yamada, Y. & Hamada, N., Jul 3 2019, In : International Journal of Radiation Biology. 95, 7, p. 816-840 25 p.

    Research output: Contribution to journal › Review article

    Open Access
    • 4 Scopus citations

    Genome effects and mutational risk of radiation

    Paunesku, T. & Woloschak, G. E., Jan 1 2019, Encyclopedia of Environmental Health. Elsevier, p. 233-244 12 p.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

    • Neuroprotective Role of Selected Antioxidant Agents in Preventing Cisplatin-Induced Damage of Human Neurons In Vitro

    Popović, J., Klajn, A., Paunesku, T., Ma, Q., Chen, S., Lai, B., Stevanović, M. & Woloschak, G. E., Jan 1 2019, In : Cellular and molecular neurobiology.

    Research output: Contribution to journal › Article

    Open Access
    • 3 Scopus citations