• 10048 Citations
1981 …2020
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Personal profile

Research Interests

My laboratory is interested in signaling mechanisms which control T helper cell differentiation and traffic. We are currently focused on two areas: functions of p38 MAP kinases (MAPK) and the role of a transcription factor KLF2 in these processes. Towards this end, we have produced novel mouse models which will allow us to test the role of the different isoforms of p38 (of which there are 4) in T helper differentiation and expression of key leukocyte adhesion molecules; and to determine the role of KLF2 downregulation in T helper biology generally.

Training Experience

1985Postdoctoral Fellowship, Stanford University
1990Postdoctoral Fellowship, University of Iowa

Education/Academic qualification

PhD, Stanford University

… → 1984

Research interests

  • Gene Regulation
  • Immunology
  • Inflammation
  • Molecular Genetics
  • Stem Cells

Fingerprint Dive into the research topics where Geoffrey Scott Kansas is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 4 Similar Profiles
P-Selectin Medicine & Life Sciences
L-Selectin Medicine & Life Sciences
Selectins Medicine & Life Sciences
Ligands Medicine & Life Sciences
E-Selectin Medicine & Life Sciences
Leukocytes Medicine & Life Sciences
galactoside 3-fucosyltransferase Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences

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Grants 2002 2020

Research Output 1981 2016

  • 10048 Citations
  • 91 Article
  • 5 Review article
7 Citations (Scopus)

Functions of smad transcription factors in TGF-β1-induced selectin ligand expression on murine CD4 Th cells

Ebel, M. E. & Kansas, G. S., Oct 1 2016, In : Journal of Immunology. 197, 7, p. 2627-2634 8 p.

Research output: Contribution to journalArticle

Transcription Factors
10 Citations (Scopus)

Diverse inflammatory cytokines induce selectin ligand expression on murine CD4 T cells via p38α MAPK

Ebel, M. E., Awe, O., Kaplan, M. H. & Kansas, G. S., Jun 15 2015, In : Journal of Immunology. 194, 12, p. 5781-5788 8 p.

Research output: Contribution to journalArticle

p38 Mitogen-Activated Protein Kinases
6 Citations (Scopus)

Defining the functional boundaries of the murine α1,3- fucosyltransferase Fut7 reveals a remarkably compact locus

Ebel, M. E. & Kansas, G. S., Mar 7 2014, In : Journal of Biological Chemistry. 289, 10, p. 6341-6349 9 p.

Research output: Contribution to journalArticle

galactoside 3-fucosyltransferase
Gene expression
Gene Expression
Traffic control
21 Citations (Scopus)

Impaired selectin-dependent leukocyte recruitment induces T-cell exhaustion and prevents chronic allograft vasculopathy and rejection

Sarraj, B., Ye, J., Akl, A. I., Chen, G., Wang, J. J., Zhang, Z. J., Abadja, F., Abecassis, M. M., Miller, S. D., Kansas, G. S. & Ansari, M. J. I., Aug 19 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 33, p. 12145-12150 6 p.

Research output: Contribution to journalArticle

Graft Survival
161 Citations (Scopus)

Therapeutic inflammatory monocyte modulation using immune-modifying microparticles

Getts, D. R., Terry, R. L., Getts, M. T., Deffrasnes, C., Müller, M., Vreden, C., Ashhurst, T. M., Chami, B., McCarthy, D., Wu, H., Jin, M., Martin, A., Shae, L. D., Witting, P., Kansas, G. S., Kühn, J., Hafezi, W., Campbell, I. L., Reilly, D., Say, J. & 8 others, Brown, L., White, M. Y., Cordwell, S. J., Chadban, S. J., Thorp, E. B., Bao, S., Miller, S. D. & King, N. J. C., Jan 15 2014, In : Science Translational Medicine. 6, 219, 219ra7.

Research output: Contribution to journalArticle

Opsonin Proteins