Grants per year
Personal profile
Research Interests
My research focuses predominantly on understanding physiological processes mediated by glutamate receptors, which are signaling proteins that respond to glutamate, the predominant excitatory neurotransmitter in the vertebrate central nervous system. Aberrant glutamate receptor signaling has been implicated in a number of pathological conditions, including epilepsy, schizophrenia and neuropathic pain; because these proteins are critical to brain function, they also are involved in most neurological diseases to varying degrees. Furthermore, modulation of glutamate receptors underlies models of learning and memory such as long-term potentiation and depression. The critical roles played by glutamate receptors in neurophysiological and neuropathological processes provide a strong impetus for understanding these fascinating molecules at many levels of study.
Training Experience
1995 | Postdoctoral Fellowship, University College, England |
1998 | Postdoctoral Fellowship, The Salk Institute |
Education/Academic qualification
PhD, University of California at Los Angeles
… → 1993
Research interests
- Cellular Electrophysiology
- Drug Discovery
- Epilepsy
- Nervous System Diseases
- Neurobiology
- Neuroscience
- Pain
- Pharmacology
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Grants
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Subproject for Dr. Swanson
National Institute of Neurological Disorders and Stroke
8/1/20 → 4/30/25
Project: Research project
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Deciphering the Roles of Kainate Receptors in Developing CNS Circuits
National Institute of Neurological Disorders and Stroke
7/15/18 → 4/30/23
Project: Research project
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Exploring Mellpaladines as New Serotonin Receptor Antagonists
Scheidt, K. A. & Swanson, G. T.
National Institute of Mental Health
7/1/18 → 5/31/21
Project: Research project
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Northwestern University Interdepartmental Neuroscience Postbaccalaureate Research Education Program
Acosta, A., Allada, R., Apkarian, A., Awatramani, R., Beeman, M., Bevan, M. D., Bozza, T. C., Cang, J., Chetkovich, D. M., Cobia, D. J., Contractor, A., Corcos, D. M., DeVries, S. H., Dewald, J. P. A., Dhar, S., Disterhoft, J. F., Dombeck, D. A., Elliott, J. M., Feng, Y., Ferreira, A. B., Gallio, M., Garcia-Anoveros, J., George Jr, A. L., Geula, C., Gordon, K. E., Gottfried, J. A., Grafman, J. H., Hartmann, M. J. Z., Heckman, C., Hespos, S. J., Jayaraman, A., Kahnt, T., Kearney, J. A., Kessler, J., Kiskinis, E., Kohtz, J., Kording, K. P., Kozorovitskiy, Y., Krainc, D., Larson, C., Lee, S. S. M., Li, L., Losh, M. C., Maccaferri, G., MacIver, M. A., Martina, M., Mazzulli, J., McLean, D., Mesulam, M., Miller, L. E., Miller, R. J., Mussa-Ivaldi, F., Nusslock, R., Opal, P., Ozdinler, P. H., Paller, K., Parrish, T. B., Prakriya, M., Radulovic, J., Raman, I. M., Reber, P. J., Redei, E., Rogalski, E., Sanchez, J. T., Sanz-Clemente, A., Savas, J. N., Schmidt, T. M., Schwartz, G. W., Segraves, M., Shepherd, G. M. G., Siddique, T., Solla, S. A., Surmeier Jr, D. J., Swanson, G. T., Topczewski, J., Tresch, M. C., Tysseling, V. M., Vassar, R. J., Voss, J. L., Wainwright, D. A., Wang, L., Weintraub, S., Woolley, C. S. & Wright, B. A.
National Institute of General Medical Sciences
5/1/17 → 4/30/22
Project: Research project
Research Output
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Auxiliary proteins are the predominant determinants of differential efficacy of clinical candidates acting as AMPA receptor positive allosteric modulators
Ishii, T., Stolz, J. R. & Swanson, G. T., May 2020, In: Molecular pharmacology. 97, 5, p. 336-350 15 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Orai1 Channels Are Essential for Amplification of Glutamate-Evoked Ca2+ Signals in Dendritic Spines to Regulate Working and Associative Memory
Maneshi, M. M., Toth, A. B., Ishii, T., Hori, K., Tsujikawa, S., Shum, A. K., Shrestha, N., Yamashita, M., Miller, R. J., Radulovic, J., Swanson, G. T. & Prakriya, M., Dec 1 2020, In: Cell reports. 33, 9, 108464.Research output: Contribution to journal › Article › peer-review
Open Access -
Phosphorylation of the HCN channel auxiliary subunit TRIP8b is altered in an animal model of temporal lobe epilepsy and modulates channel function
Foote, K. M., Lyman, K. A., Han, Y., Michailidis, I. E., Heuermann, R. J., Mandikian, D., Trimmer, J. S., Swanson, G. T. & Chetkovich, D. M., Oct 25 2019, In: Journal of Biological Chemistry. 294, 43, p. 15743-15758 16 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Peripherally derived T regulatory and γδ T cells have opposing roles in the pathogenesis of intractable pediatric epilepsy
Xu, D., Robinson, A. P., Ishii, T., Duncan, DA. S., Alden, T. D., Goings, G. E., Ifergan, I., Podojil, J. R., Penaloza-MacMaster, P., Kearney, J. A., Swanson, G. T., Miller, S. D. & Koh, S., Apr 1 2018, In: Journal of Experimental Medicine. 215, 4, p. 1169-1186 18 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Cadherin-10 maintains excitatory/inhibitory ratio through interactions with synaptic proteins
Smith, K. R., Jones, K. A., Kopeikina, K. J., Burette, A. C., Copits, B. A., Yoon, S., Forrest, M. P., Fawcett-Patel, J. M., Hanley, J. G., Weinberg, R. J., Swanson, G. T. & Penzes, P., Nov 15 2017, In: Journal of Neuroscience. 37, 46, p. 11127-11139 13 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations