Geoffrey T Swanson

Professor, Pharmacology
Professor, Neurobiology
Driskill Graduate Training Program in Life Sciences
Director NUIN, Northwestern University Interdepartmental Neuroscience PhD Program (NUIN)
Northwestern University Interdepartmental Neuroscience PhD Program (NUIN)

Phone312/503-1052
Emailgtswanson@northwestern.edu

4427 Citations

Research output per year

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Personal profile

Research Interests

My research focuses predominantly on understanding physiological processes mediated by glutamate receptors, which are signaling proteins that respond to glutamate, the predominant excitatory neurotransmitter in the vertebrate central nervous system. Aberrant glutamate receptor signaling has been implicated in a number of pathological conditions, including epilepsy, schizophrenia and neuropathic pain; because these proteins are critical to brain function, they also are involved in most neurological diseases to varying degrees. Furthermore, modulation of glutamate receptors underlies models of learning and memory such as long-term potentiation and depression. The critical roles played by glutamate receptors in neurophysiological and neuropathological processes provide a strong impetus for understanding these fascinating molecules at many levels of study.

Training Experience

1995	Postdoctoral Fellowship, University College, England
1998	Postdoctoral Fellowship, The Salk Institute

Education/Academic qualification

PhD, University of California-Los Angeles

… → 1993

Research interests

Cellular Electrophysiology
Drug Discovery
Epilepsy
Nervous System Diseases
Neurobiology
Neuroscience
Pain
Pharmacology

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Grants

4 Active
24 Finished

Deciphering the Roles of Kainate Receptors in Developing CNS Circuits

Savas, J. N. & Swanson, G. T.

National Institute of Neurological Disorders and Stroke

7/15/18 → 4/30/23

Project: Research project

Exploring Mellpaladines as New Serotonin Receptor Antagonists

Scheidt, K. A. & Swanson, G. T.

National Institute of Mental Health

7/1/18 → 5/31/20

Project: Research project

Northwestern University Interdepartmental Neuroscience Postbaccalaureate Research Education Program

Acosta, A., Allada, R., Apkarian, A., Awatramani, R., Beeman, M., Bevan, M. D., Bozza, T. C., Cang, J., Chetkovich, D. M., Cobia, D. J., Contractor, A., Corcos, D. M., DeVries, S. H., Dewald, J. P. A., Dhar, S., Disterhoft, J. F., Dombeck, D. A., Elliott, J. M., Feng, Y., Ferreira, A. B., Gallio, M., Garcia-Anoveros, J., George Jr, A. L., Geula, C., Gordon, K. E., Gottfried, J. A., Grafman, J. H., Hartmann, M. J. Z., Heckman, C., Hespos, S. J., Jayaraman, A., Kahnt, T., Kearney, J. A., Kessler, J., Kiskinis, E., Kohtz, J., Kording, K. P., Kozorovitskiy, Y., Krainc, D., Larson, C., Lee, S. S. M., Li, L., Losh, M. C., Maccaferri, G., MacIver, M. A., Martina, M., Mazzulli, J., McLean, D., Mesulam, M., Miller, L. E., Miller, R. J., Mussa-Ivaldi, F., Nusslock, R., Opal, P., Ozdinler, P. H., Paller, K., Parrish, T. B., Prakriya, M., Radulovic, J., Raman, I. M., Reber, P. J., Redei, E., Rogalski, E., Sanchez, J. T., Sanz-Clemente, A., Savas, J. N., Schmidt, T. M., Schwartz, G. W., Segraves, M., Shepherd, G. M. G., Siddique, T., Solla, S. A., Surmeier Jr, D. J., Swanson, G. T., Topczewski, J., Tresch, M. C., Tysseling, V. M., Vassar, R. J., Voss, J. L., Wainwright, D. A., Wang, L., Weintraub, S., Woolley, C. S. & Wright, B. A.

National Institute of General Medical Sciences

5/1/17 → 4/30/22

Project: Research project

Store-Operated Channels in the Nervous System

Prakriya, M., Silinsky, E. M., Silinsky, E. M., Swanson, G. T. & Yamashita, M.

National Institute of Neurological Disorders and Stroke

1/1/17 → 12/31/20

Project: Research project

Beta-arrestin signaling dependent modulation of glutamatergic transmission in the extended amygdala mediates stress and anxiety behavior

Swanson, G. T.

Brain & Behavior Research Foundation

7/15/17 → 7/31/18

Project: Research project

Research Output

4427 Citations
72 Article
6 Review article
2 Short survey
2 Patent
1 More
- 1 Chapter

Phosphorylation of the HCN channel auxiliary subunit TRIP8b is altered in an animal model of temporal lobe epilepsy and modulates channel function

Foote, K. M., Lyman, K. A., Han, Y., Michailidis, I. E., Heuermann, R. J., Mandikian, D., Trimmer, J. S., Swanson, G. T. & Chetkovich, D. M., Jan 1 2019, In : Journal of Biological Chemistry. 294, 43, p. 15743-15758 16 p.