• 2576 Citations
1989 …2024

Research output per year

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Personal profile

Research Interests

Brain functions are the result of the coordinated activity of large networks of neurons, which are composed by many different cell types. As a consequence, the specific properties of synaptic communication between different types of neurons play a pivotal role in shaping the computational power and network activity of specific brain regions. Research in my laboratory is focused on the hippocampus, which is an area of the brain involved in higher cognitive functions, such as learning and memory, and is often affected by important neurological illnesses like epilepsy, schizophrenia and Alzheimer’s disease. In particular, we are interested in the synaptic properties of GABAergic inhibitory interneurons, which are a very heterogeneous cellular population, with wide anatomical and functional diversity. Additionally we are trying to unravel the network properties of Cajal-Retzius cells, which are a neuronal population involved in guiding cortical development, whose computational functions remain poorly understood. Methodologically, we use state-of-the-art electrophysiological techniques in vitro such as paired recordings from anatomically identified connected neurons and optogenetic control of specific cellular populations. We hope that relating different neuronal types to clear network functions may lead to a better understanding of the cellular and molecular basis of hippocampal activity, and generate important insight into the organizing principles of cortical networks in the normal brain and during disease.

Education/Academic qualification

PhD, University of Milan

… → 1993

MD, University of Milan

… → 1989

Research interests

  • Biophysics
  • Cellular Electrophysiology
  • Computational Neuroscience
  • Developmental Neurobiology
  • Nervous System Diseases
  • Neurobiology
  • Neuroscience
  • Pharmacology

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Grants

  • Research Output

    Open Access
  • 2 Scopus citations
  • Cajal-Retzius cells and GABAergic interneurons of the developing hippocampus: Close electrophysiological encounters of the third kind

    Anstötz, M., Quattrocolo, G. & Maccaferri, G., Oct 15 2018, In : Brain research. 1697, p. 124-133 10 p.

    Research output: Contribution to journalReview article

  • 2 Scopus citations

    Experience-Dependent Regulation of Cajal-Retzius Cell Networks in the Developing and Adult Mouse Hippocampus

    Anstötz, M., Lee, S. K., Neblett, T. I., Rune, G. M. & Maccaferri, G., Feb 1 2018, In : Cerebral Cortex. 28, 2, p. 672-687 16 p.

    Research output: Contribution to journalArticle

  • 8 Scopus citations
  • 7 Scopus citations