Gregory J Beitel

  • 2210 Citations
1986 …2019
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Personal profile

Research Interests

Use molecular/genetic approaches with Drosophila to investigate two areas: 1) Understanding how individual cells control their shapes and coordinate with other cells to create the complex epithelial tubular networks found in multicellular organisms. 2) Understanding how non-neuronal cells sense and respond to elevated levels of CO2 (hypercapnia) such as those present in patients with obstructive disease.  Our work has identified conserved genes that mediate hypercapnic suppression of innate immune responses in flies and mammals.

Education/Academic qualification

PhD, Massachusetts Institute of Technology

… → 1994

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  • 3 Similar Profiles
Drosophila Medicine & Life Sciences
Hypercapnia Medicine & Life Sciences
Morphogenesis Medicine & Life Sciences
Caenorhabditis elegans Medicine & Life Sciences
Mutation Medicine & Life Sciences
Genes Medicine & Life Sciences
Cell Shape Medicine & Life Sciences
Intercellular Junctions Medicine & Life Sciences

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Grants 2002 2019

Drosophila
Apoptosis
Blood Vessels
Growth
Trachea
Hypercapnia
Diptera
Mammals
Drosophila
Genes

Hartmann Subproject

Beitel, G. J.

Howard Hughes Medical Institute

9/1/119/30/14

Project: Research project

Klein Subproject

Beitel, G. J.

Howard Hughes Medical Institute

9/1/119/30/14

Project: Research project

Research Output 1986 2019

1 Citation (Scopus)

QuBiT: A quantitative tool for analyzing epithelial tubes reveals unexpected patterns of organization in the Drosophila trachea

Yang, R., Li, E., Kwon, Y. J., Mani, M. & Beitel, G. J., Jun 1 2019, In : Development (Cambridge). 146, 12, dev172759.

Research output: Contribution to journalArticle

Open Access
Trachea
Drosophila
Morphogenesis
Cell Shape
Periodicity

The Caspase-3 homolog DrICE regulates endocytic trafficking during Drosophila tracheal morphogenesis

McSharry, S. S. & Beitel, G. J., Dec 1 2019, In : Nature communications. 10, 1, 1031.

Research output: Contribution to journalArticle

Drosophila
Caspases
Morphogenesis
Caspase 3
apoptosis
1 Citation (Scopus)

Design, implementation, and evaluation of a multi-disciplinary professional development program for research mentors

Brace, J. L., Baiduc, R. R., Drane, D. L., Flores, L. C., Beitel, G. J. & Lo, S. M., Aug 8 2018, In : Mentoring and Tutoring: Partnership in Learning. 26, 4, p. 377-399 23 p.

Research output: Contribution to journalArticle

evaluation
mentoring
student
graduate
mathematics
1 Citation (Scopus)
Hypercapnia
Nucleosomes
Lipid Metabolism
Epithelial Cells
Carbon Monoxide

A comparison of nucleosome organization in Drosophila cell lines

Martin, R. L., Maiorano, J., Beitel, G. J., Marko, J. F., McVicker, G. & Fondufe-Mittendorf, Y. N., Jun 1 2017, In : PloS one. 12, 6, e0178590.

Research output: Contribution to journalArticle

nucleosomes
Nucleosomes
Drosophila
Cells
cell lines