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Gregory J Beitel

  • 2296 Citations
1986 …2019

Research output per year

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Personal profile

Research Interests

Use molecular/genetic approaches with Drosophila to investigate two areas: 1) Understanding how individual cells control their shapes and coordinate with other cells to create the complex epithelial tubular networks found in multicellular organisms. 2) Understanding how non-neuronal cells sense and respond to elevated levels of CO2 (hypercapnia) such as those present in patients with obstructive disease.  Our work has identified conserved genes that mediate hypercapnic suppression of innate immune responses in flies and mammals.

Education/Academic qualification

PhD, Massachusetts Institute of Technology

… → 1994

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Grants

Tube size control by Src and Yorkie/YAP

Beitel, G. J.

National Institute of General Medical Sciences

2/1/14 → 1/31/19

Project: Research project

    • Genes Mediating Innate Immune Suppression by Hypercapnia in Mammals and Flies

    Beitel, G. J. & Sporn, P. H.

    National Heart, Lung, and Blood Institute

    12/15/11 → 11/30/16

    Project: Research project

    • Hartmann Subproject

    Beitel, G. J.

    Howard Hughes Medical Institute

    9/1/11 → 9/30/14

    Project: Research project

    Brown Subproject

    Beitel, G. J.

    Howard Hughes Medical Institute

    9/1/11 → 9/30/14

    Project: Research project

    Perreault Subproject

    Beitel, G. J.

    Howard Hughes Medical Institute

    9/1/11 → 9/30/14

    Project: Research project

    Research Output

    Elevated CO2 regulates the Wnt signaling pathway in mammals, Drosophila melanogaster and Caenorhabditis elegans

    Shigemura, M., Lecuona, E., Angulo, M., Dada, L. A., Edwards, M. B., Welch, L. C., Casalino-Matsuda, S. M., Sporn, P. H. S., Vadász, I., Helenius, I. T., Nader, G. A., Gruenbaum, Y., Sharabi, K., Cummins, E., Taylor, C., Bharat, A., Gottardi, C. J., Beitel, G. J., Kaminski, N., Budinger, G. R. S. & 2 others, Berdnikovs, S. & Sznajder, J. I., Dec 1 2019, In : Scientific reports. 9, 1, 18251.

    Research output: Contribution to journal › Article

    Open Access

    • QuBiT: A quantitative tool for analyzing epithelial tubes reveals unexpected patterns of organization in the Drosophila trachea

    Yang, R., Li, E., Kwon, Y. J., Mani, M. & Beitel, G. J., Jun 2019, In : Development (Cambridge). 146, 12, dev172759.

    Research output: Contribution to journal › Article

    Open Access
    • 1 Scopus citations

    The Caspase-3 homolog DrICE regulates endocytic trafficking during Drosophila tracheal morphogenesis

    McSharry, S. S. & Beitel, G. J., Dec 1 2019, In : Nature communications. 10, 1, 1031.

    Research output: Contribution to journal › Article

    • 2 Scopus citations

    Design, implementation, and evaluation of a multi-disciplinary professional development program for research mentors

    Brace, J. L., Baiduc, R. R., Drane, D. L., Flores, L. C., Beitel, G. J. & Lo, S. M., Aug 8 2018, In : Mentoring and Tutoring: Partnership in Learning. 26, 4, p. 377-399 23 p.

    Research output: Contribution to journal › Article

    • 1 Scopus citations

    Hypercapnia Alters Expression of Immune Response, Nucleosome Assembly and Lipid Metabolism Genes in Differentiated Human Bronchial Epithelial Cells

    Casalino-Matsuda, S. M., Wang, N., Ruhoff, P. T., Matsuda, H., Nlend, M. C., Nair, A., Szleifer, I., Beitel, G. J., Sznajder, J. I. & Sporn, P. H. S., Dec 1 2018, In : Scientific reports. 8, 1, 13508.

    Research output: Contribution to journal › Article

    • 6 Scopus citations