Grants per year
Personal profile
Research Interests
Surgical Pathology
The long-term objective of our research is to study molecular mechanism and chemoprevention of chronic inflammation-driven carcinogenesis. The specific areas of interest are 1) to develop a molecular mimicking model of ulcerative colitis-associated carcinogenesis in rodents, and further to elucidate the role of inflammation-caused and dietary iron-enhanced nitro-oxidative stress and inflammatory mediators in DNA damage, cell proliferation and inflammation-driven carcinogenesis; 2) to study the pathogenesis and molecular biomarkers of pancreatic carcinoma in genetically engineered mouse model and in human; and 3) to develop an efficient strategy on the prevention of chronic inflammation-driven carcinogenesis, particularly interested in dietary nutrients, antioxidants, green tea and inositol compounds and specifically targeted on colorectal, pancreatic, and liver carcinogenesis.
Certifications and Licenses
| Anatomic Pathology & Clinical Pathology |
Training Experience
| 2004 | Residency, New York University Medical Center |
| 2005 | Fellowship, Johns Hopkins Hospital |
Education/Academic qualification
PhD, China Medical University
… → 1992
MD, China Medical University
… → 1983
Keywords
- Cancer Biology
- Inflammatory Bowel Disease
- Liver Disease / Pathobiology
- Pancreatic Disorders
- Pathology
- Digestive Cancer (esophagus, stomach, colon, rectum)
Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.
- 9 Similar Profiles
Carcinogenesis
Medicine & Life Sciences
Neoplasms
Medicine & Life Sciences
Tea
Medicine & Life Sciences
Adenocarcinoma
Medicine & Life Sciences
Eosinophilic Esophagitis
Medicine & Life Sciences
Epoxide Hydrolases
Medicine & Life Sciences
Ulcerative Colitis
Medicine & Life Sciences
Liver
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2005 2023
Disordered Tissue Biomechanics as a Driver of Esophageal Disease
Budinger, G. S., Carlson, D. A., Ciolino, J. D., Espinosa, H. D., Gonsalves, N. P., Hinchcliff, M. E., Hirano, I., Kahrilas, P. J., Pandolfino, J. E., Passman, R. S., Patankar, N. A., Taft, T. N., Tetreault, M. & Yang, G.
National Institute of Diabetes, Digestive and Kidney Diseases
7/15/18 → 6/30/23
Project: Research project
Esophageal Diseases
Deglutition Disorders
Biomechanical Phenomena
Esophagus
Mechanical Phenomena
Profiling unique eosinophile-generated eicosanoid metabolites in eosinophilic esophagitis using a liquid chromatography tandem mass spectrometry (LC-MS/MS)-based metabolomics approach
Northwestern Memorial Hospital, Digestive Health Foundation
7/1/18 → 6/30/19
Project: Research project
Eicosanoids
Liquid chromatography
Metabolites
Unsaturated Fatty Acids
Mass spectrometry
MRI-Guided Dendritic-Cell-Based Vaccine Immunotherapy for Pancreatic Cancer
Kim, D., Larson, A. C., Yang, G. & Zhang, Z.
8/1/16 → 7/31/21
Project: Research project
Pancreatic Neoplasms
Immunotherapy
Dendritic Cells
Vaccines
Magnetic Resonance Imaging
Inhibition of pancreatic carcinogenesis via targeting c-Raf and sEH
5/1/16 → 10/31/19
Project: Research project
Omega-3 derived epoxy fatty acids and sEH in pancreatitis-induced carcinogenesis
Jiang, H., Liao, J. & Yang, G.
National Institute of Diabetes, Digestive and Kidney Diseases
4/5/16 → 3/31/20
Project: Research project
Epoxide Hydrolases
Epoxy Compounds
Pancreatitis
Unsaturated Fatty Acids
Carcinogenesis
Research Output 1995 2019
1
Citation
(Scopus)
Consortium of Eosinophilic Gastrointestinal Disease Researchers: Advancing the Field of Eosinophilic GI Disorders Through Collaboration
Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR), Mar 1 2019, In : Gastroenterology. 156, 4, p. 838-842 5 p.Research output: Contribution to journal › Editorial
Gastrointestinal Diseases
Research Personnel
Uncommon Intraluminal Tumors of the Gallbladder and Biliary Tract: Spectrum of Imaging Appearances
Chatterjee, A., Lopes Vendrami, C., Nikolaidis, P., Mittal, P. K., Bandy, A. J., Menias, C. O., Hammond, N. A., Yaghmai, V., Yang, G-Y. & Miller, F. H., Mar 1 2019, In : Radiographics : a review publication of the Radiological Society of North America, Inc. 39, 2, p. 388-412 25 p.Research output: Contribution to journal › Article
Biliary Tract
Gallbladder
Neoplasms
Bile Duct Neoplasms
Adenocarcinoma
9
Citations
(Scopus)
A common antimicrobial additive increases colonic inflammation and colitis-associated colon tumorigenesis in mice
Yang, H., Wang, W., Romano, K. A., Gu, M., Sanidad, K. Z., Kim, D., Yang, J., Schmidt, B., Panigrahy, D., Pei, R., Martin, D. A., Ilker Ozay, E., Wang, Y., Song, M., Bolling, B. W., Xiao, H., Minter, L. M., Yang, G-Y., Liu, Z., Rey, F. E. & 1 others, May 30 2018, In : Science translational medicine. 10, 443, eaan4116.Research output: Contribution to journal › Article
Triclosan
Colitis
Colon
Carcinogenesis
Inflammation
2
Citations
(Scopus)
Alignment of parent- and child-reported outcomes and histology in eosinophilic esophagitis across multiple CEGIR sites
Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR), Jul 1 2018, In : Journal of Allergy and Clinical Immunology. 142, 1, p. 130-138.e1Research output: Contribution to journal › Article
Eosinophilic Esophagitis
Histology
Quality of Life
Parents
Pediatrics
2
Citations
(Scopus)
Anaplastic thyroid carcinoma: an epidemiologic, histologic, immunohistochemical, and molecular single-institution study
Deeken-Draisey, A., Yang, G-Y., Gao, J. & Alexiev, B. A., Dec 1 2018, In : Human Pathology. 82, p. 140-148 9 p.Research output: Contribution to journal › Article
Thyroid Neoplasms
Mutation
Anaplastic Large-Cell Lymphoma
Neoplasms
Small Cell Carcinoma