Grants per year
Personal profile
Research Interests
Surgical Pathology
The long-term objective of our research is to study molecular mechanism and chemoprevention of chronic inflammation-driven carcinogenesis. The specific areas of interest are 1) to develop a molecular mimicking model of ulcerative colitis-associated carcinogenesis in rodents, and further to elucidate the role of inflammation-caused and dietary iron-enhanced nitro-oxidative stress and inflammatory mediators in DNA damage, cell proliferation and inflammation-driven carcinogenesis; 2) to study the pathogenesis and molecular biomarkers of pancreatic carcinoma in genetically engineered mouse model and in human; and 3) to develop an efficient strategy on the prevention of chronic inflammation-driven carcinogenesis, particularly interested in dietary nutrients, antioxidants, green tea and inositol compounds and specifically targeted on colorectal, pancreatic, and liver carcinogenesis.
Certifications and Licenses
Anatomic Pathology & Clinical Pathology |
Training Experience
2004 | Residency, New York University Medical Center |
2005 | Fellowship, Johns Hopkins Hospital |
Education/Academic qualification
PhD, China Medical University
… → 1992
MD, China Medical University
… → 1983
Research interests
- Cancer Biology
- Inflammatory Bowel Disease
- Liver Disease / Pathobiology
- Pancreatic Disorders
- Pathology
- Digestive Cancer (esophagus, stomach, colon, rectum)
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Grants
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Neutrophils modulate DNA Damage Repair to promote survival/progression of colorectal cancer
U.S. Army Medical Research and Materiel Command
9/1/20 → 8/31/22
Project: Research project
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Critical role of p53 gene mutation in ulcerative colitis-driving carcinogenesis.
Northwestern Memorial Hospital, Digestive Health Foundation
6/1/20 → 12/31/21
Project: Research project
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Consortium of Eosinophilic Gastrointestinal Disease Researchers
Cincinnati Children's Hospital Medical Center, National Institute of Allergy and Infectious Diseases
9/17/19 → 8/31/24
Project: Research project
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Research Output
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Advances in Rejection Management: Prevention and Treatment
Harrington, C. R., Yang, G. Y. & Levitsky, J., Feb 2021, In: Clinics in liver disease. 25, 1, p. 53-72 20 p.Research output: Contribution to journal › Review article › peer-review
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Advancing patient care through the Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR)
Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR), Jan 2020, In: Journal of Allergy and Clinical Immunology. 145, 1, p. 28-37 10 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
A phase I trial of berberine in Chinese with ulcerative colitis
Xu, L., Zhang, Y., Xue, X., Liu, J., Li, Z. S., Yang, G. Y., Song, Y., Pan, Y., Ma, Y., Hu, S., Wen, A., Jia, Y., Rodriguez, L. M., Tull, M. B., Benante, K., Khan, S. A., Cao, Y., Jovanovic, B., Richmond, E., Umar, A. & 2 others, , 2020, In: Cancer Prevention Research. 13, 1, p. 117-126 10 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Esophageal type 2 cytokine expression heterogeneity in eosinophilic esophagitis in a multisite cohort
Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR), Jun 2020, In: Journal of Allergy and Clinical Immunology. 145, 6, p. 1629-1640.e4Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Immunosuppression Withdrawal in Liver Transplant Recipients on Sirolimus
Levitsky, J., Burrell, B. E., Kanaparthi, S., Turka, L. A., Kurian, S., Sanchez-Fueyo, A., Lozano, J. J., Demetris, A., Lesniak, A., Kirk, A. D., Stempora, L., Yang, G. Y. & Mathew, J. M., Aug 1 2020, In: Hepatology. 72, 2, p. 569-583 15 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations