No photo of Guang-Yu Yang

View Scopus Profile

Guang-Yu Yang

  • 8584 Citations
1995 …2023

Research output per year

If you made any changes in Pure these will be visible here soon.

Personal profile

Research Interests

Surgical Pathology

The long-term objective of our research is to study molecular mechanism and chemoprevention of chronic inflammation-driven carcinogenesis. The specific areas of interest are 1) to develop a molecular mimicking model of ulcerative colitis-associated carcinogenesis in rodents, and further to elucidate the role of inflammation-caused and dietary iron-enhanced nitro-oxidative stress and inflammatory mediators in DNA damage, cell proliferation and inflammation-driven carcinogenesis; 2) to study the pathogenesis and molecular biomarkers of pancreatic carcinoma in genetically engineered mouse model and in human; and 3) to develop an efficient strategy on the prevention of chronic inflammation-driven carcinogenesis, particularly interested in dietary nutrients, antioxidants, green tea and inositol compounds and specifically targeted on colorectal, pancreatic, and liver carcinogenesis.

Certifications and Licenses

Anatomic Pathology & Clinical Pathology

Training Experience

2004Residency, New York University Medical Center
2005Fellowship, Johns Hopkins Hospital

Education/Academic qualification

PhD, China Medical University

… → 1992

MD, China Medical University

… → 1983

Research interests

  • Cancer Biology
  • Inflammatory Bowel Disease
  • Liver Disease / Pathobiology
  • Pancreatic Disorders
  • Pathology
  • Digestive Cancer (esophagus, stomach, colon, rectum)

Fingerprint Dive into the research topics where Guang-Yu Yang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants

Disordered Tissue Biomechanics as a Driver of Esophageal Disease

Budinger, G. S., Carlson, D. A., Ciolino, J. D., Espinosa, H. D., Gonsalves, N. P., Hinchcliff, M. E., Hirano, I., Kahrilas, P. J., Pandolfino, J. E., Passman, R. S., Patankar, N. A., Taft, T. N., Tetreault, M. & Yang, G.

National Institute of Diabetes, Digestive and Kidney Diseases

7/15/18 → 6/30/23

Project: Research project

    • Profiling unique eosinophile-generated eicosanoid metabolites in eosinophilic esophagitis using a liquid chromatography tandem mass spectrometry (LC-MS/MS)-based metabolomics approach

    Yang, G.

    Northwestern Memorial Hospital, Digestive Health Foundation

    7/1/18 → 6/30/20

    Project: Research project

    • MRI-Guided Dendritic-Cell-Based Vaccine Immunotherapy for Pancreatic Cancer

    Kim, D., Larson, A. C., Yang, G. & Zhang, Z.

    National Cancer Institute

    8/1/16 → 7/31/21

    Project: Research project

    • Omega-3 derived epoxy fatty acids and sEH in pancreatitis-induced carcinogenesis

    Jiang, H., Liao, J. & Yang, G.

    National Institute of Diabetes, Digestive and Kidney Diseases

    4/5/16 → 3/31/21

    Project: Research project

    • Consortium of Eosinophilic Gastrointestinal Disease Researchers

    Yang, G.

    Cincinnati Children's Hospital Medical Center, National Institute of Allergy and Infectious Diseases

    8/1/18 → 7/31/19

    Project: Research project

    • Research Output

    Advancing patient care through the Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR)

    Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR), Jan 2020, In : Journal of Allergy and Clinical Immunology. 145, 1, p. 28-37 10 p.

    Research output: Contribution to journal › Article

    • Molecular, endoscopic, histologic, and circulating biomarker-based diagnosis of eosinophilic gastritis: Multi-site study

    Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR), Jan 2020, In : Journal of Allergy and Clinical Immunology. 145, 1, p. 255-269 15 p.

    Research output: Contribution to journal › Article

    • 2 Scopus citations

    Consortium of Eosinophilic Gastrointestinal Disease Researchers: Advancing the Field of Eosinophilic GI Disorders Through Collaboration

    Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR), Mar 2019, In : Gastroenterology. 156, 4, p. 838-842 5 p.

    Research output: Contribution to journal › Editorial

    7 Scopus citations

    Epoxy-oxylipins and soluble epoxide hydrolase metabolic pathway as targets for NSAID-induced gastroenteropathy and inflammation-associated carcinogenesis

    Jones, R. D., Liao, J., Tong, X., Xu, D., Sun, L., Li, H. & Yang, G. Y., Jan 1 2019, In : Frontiers in Pharmacology. 10, JUN, 731.

    Research output: Contribution to journal › Review article

    Open Access

    • Inhibition of mutant Kras and p53-driven pancreatic carcinogenesis by atorvastatin: Mainly via targeting of the farnesylated DNAJA1 in chaperoning mutant p53

    Xu, D., Tong, X., Sun, L., Li, H., Jones, R. D., Liao, J. & Yang, G. Y., Nov 1 2019, In : Molecular Carcinogenesis. 58, 11, p. 2052-2064 13 p.

    Research output: Contribution to journal › Article