Guoxiang Liu

  • 600 Citations
20062019

Research output per year

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Research Output

  • 600 Citations
  • 17 Article
  • 2 Review article
2019

Lysine 68 acetylation directs MnSOD as a tetrameric detoxification complex versus a monomeric tumor promoter

Zhu, Y., Zou, X., Dean, A. E., Brien, J. O., Gao, Y., Tran, E. L., Park, S. H., Liu, G., Kieffer, M. B., Jiang, H., Stauffer, M. E., Hart, R., Quan, S., Satchell, K. J. F., Horikoshi, N., Bonini, M. & Gius, D., Dec 1 2019, In : Nature communications. 10, 1, 2399.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations
2017

Loss of NAD-Dependent Protein Deacetylase Sirtuin-2 Alters Mitochondrial Protein Acetylation and Dysregulates Mitophagy

Liu, G., Park, S. H., Imbesi, M., Nathan, W. J., Zou, X., Zhu, Y., Jiang, H., Parisiadou, L. & Gius, D., May 20 2017, In : Antioxidants and Redox Signaling. 26, 15, p. 846-863 18 p.

Research output: Contribution to journalArticle

34 Scopus citations

SIRT3-mediated dimerization of IDH2 directs cancer cell metabolism and tumor growth

Zou, X., Zhu, Y., Park, S. H., Liu, G., O'Brien, J., Jiang, H. & Gius, D., Aug 1 2017, In : Cancer Research. 77, 15, p. 3990-3999 10 p.

Research output: Contribution to journalArticle

22 Scopus citations
2016

SIRT2-mediated deacetylation and tetramerization of pyruvate kinase directs glycolysis and tumor growth

Park, S. H., Ozden, O., Liu, G., Song, H. Y., Zhu, Y., Yan, Y., Zou, X., Kang, H. J., Jiang, H., Principe, D. R., Cha, Y. I., Roh, M., Vassilopoulos, A. & Gius, D., Jul 1 2016, In : Cancer Research. 76, 13, p. 3802-3812 11 p.

Research output: Contribution to journalArticle

36 Scopus citations
2015

No apparent transmission of transgenic α-synuclein into nigrostriatal dopaminergic neurons in multiple mouse models

Sastry, N., Zheng, W., Liu, G., Wang, H., Chen, X., Cai, M., Contractor, P., Sgobio, C., Sun, L., Xie, C. & Cai, H., Dec 3 2015, In : Translational Neurodegeneration. 4, 1, 23.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Selective expression of Parkinson's disease-related Leucine-rich repeat kinase 2 G2019S missense mutation in midbrain dopaminergic neurons impairs dopamine release and dopaminergic gene expression

Liu, G., Sgobio, C., Gu, X., Sun, L., Lin, X., Yu, J., Parisiadou, L., Xie, C., Sastry, N., Ding, J., Lohr, K. M., Miller, G. W., Mateo, Y., Lovinger, D. M. & Cai, H., Apr 9 2015, In : Human molecular genetics. 24, 18, p. 5299-5312 14 p.

Research output: Contribution to journalArticle

17 Scopus citations
2014

Aldehyde dehydrogenase 1 defines and protects a nigrostriatal dopaminergic neuron subpopulation

Liu, G., Yu, J., Ding, J., Xie, C., Sun, L., Rudenko, I., Zheng, W., Sastry, N., Luo, J., Rudow, G., Troncoso, J. C. & Cai, H., Jul 1 2014, In : Journal of Clinical Investigation. 124, 7, p. 3032-3046 15 p.

Research output: Contribution to journalArticle

Open Access
48 Scopus citations
Open Access
13 Scopus citations

LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity

Parisiadou, L., Yu, J., Sgobio, C., Xie, C., Liu, G., Sun, L., Gu, X. L., Lin, X., Crowley, N. A., Lovinger, D. M. & Cai, H., Mar 1 2014, In : Nature Neuroscience. 17, 3, p. 367-376 10 p.

Research output: Contribution to journalArticle

91 Scopus citations
2013

Gamma aminobutyric acid transporter subtype 1 gene knockout mice: A new model for attention deficit/hyperactivity disorder

Yang, P., Cai, G., Cai, Y., Fei, J. & Liu, G., Jul 1 2013, In : Acta biochimica et biophysica Sinica. 45, 7, p. 578-585 8 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Mutations in GBA2 cause autosomal-recessive cerebellar ataxia with spasticity

Hammer, M. B., Eleuch-Fayache, G., Schottlaender, L. V., Nehdi, H., Gibbs, J. R., Arepalli, S. K., Chong, S. B., Hernandez, D. G., Sailer, A., Liu, G., Mistry, P. K., Cai, H., Shrader, G., Sassi, C., Bouhlal, Y., Houlden, H., Hentati, F., Amouri, R. & Singleton, A. B., Feb 7 2013, In : American journal of human genetics. 92, 2, p. 245-251 7 p.

Research output: Contribution to journalArticle

Open Access
79 Scopus citations
2012

Enhanced learning and memory in GAT1 heterozygous mice.

Shi, J., Cai, Y., Liu, G., Gong, N., Liu, Z., Xu, T., Wang, Z. & Fei, J., Apr 2012, In : Acta biochimica et biophysica Sinica. 44, 4, p. 359-366 8 p.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations

α-synuclein, LRRK2 and their interplay in Parkinson's disease

Liu, G., Aliaga, L. & Cai, H., Mar 1 2012, In : Future Neurology. 7, 2, p. 145-153 9 p.

Research output: Contribution to journalReview article

Open Access
23 Scopus citations
2008

Characterization of the target DNA sequence for the DNA-binding domain of zinc finger protein 191

Wang, H., Sun, R., Liu, G., Yao, M., Fei, J. & Shen, H., Aug 1 2008, In : Acta biochimica et biophysica Sinica. 40, 8, p. 704-710 7 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Improved method to raise polyclonal antibody using enhanced green fluorescent protein transgenic mice

Ren, J., Wang, L., Liu, G., Zhang, W., Sheng, Z., Wang, Z. & Fei, J., Feb 1 2008, In : Acta biochimica et biophysica Sinica. 40, 2, p. 111-115 5 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

γ-Aminobutyric acid transporter 1 negatively regulates T cell-mediated immune responses and ameliorates autoimmune inflammation in the CNS

Wang, Y., Feng, D., Liu, G., Luo, Q., Xu, Y., Lin, S., Fei, J. & Xu, L., Dec 15 2008, In : Journal of Immunology. 181, 12, p. 8226-8236 11 p.

Research output: Contribution to journalArticle

Open Access
34 Scopus citations
2007

Reduced aggression in mice lacking GABA transporter subtype 1

Liu, G., Liu, S., Cai, G. Q., Sheng, Z. J., Cai, Y. Q., Jiang, J., Sun, X., Ma, S. K., Wang, L., Wang, Z. G. & Fei, J., Feb 15 2007, In : Journal of Neuroscience Research. 85, 3, p. 649-655 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Reduced anxiety and depression-like behaviors in mice lacking GABA transporter subtype 1

Liu, G., Cai, G. Q., Cai, Y. Q., Sheng, Z. J., Jiang, J., Mei, Z., Wang, Z. G., Guo, L. & Fei, J., Jul 1 2007, In : Neuropsychopharmacology. 32, 7, p. 1531-1539 9 p.

Research output: Contribution to journalArticle

Open Access
86 Scopus citations
2006

Mice with genetically altered GABA transporter subtype I (GAT1) expression show altered behavioral responses to ethanol

Cai, Y. Q., Cai, G. Q., Liu, G., Cai, Q., Shi, J. H., Shi, J., Ma, S. K., Sun, X., Sheng, Z. J., Mei, Z. T., Cui, D., Guo, L., Wang, Z. & Fei, J., Aug 1 2006, In : Journal of Neuroscience Research. 84, 2, p. 255-267 13 p.

Research output: Contribution to journalArticle

37 Scopus citations