Grants per year
Personal profile
Research Interests
Neisseria gonorrhoeae, gonorrhea, Neisseria meningitidis, pilus, antigenic variation, recombination, DNA transformation, DNA replication, DNA repair, antioxidant functions, reactive oxygen species (ROS), neutrophil interactions. epithelium interactions
Education/Academic qualification
PhD, Pennsylvania State University
… → 1983
Research interests
- DNA Recombination
- DNA Repair
- Genetics: Microbial
- Genomics
- Infectious Diseases: Bacteria
- Inflammation
- Microbial Pathogenesis
- Microbiology
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Neisseria gonorrhoeae
Medicine & Life Sciences
Fimbriae Proteins
Medicine & Life Sciences
Antigenic Variation
Medicine & Life Sciences
Neisseria
Medicine & Life Sciences
DNA
Medicine & Life Sciences
Genetic Recombination
Medicine & Life Sciences
Genes
Medicine & Life Sciences
Neisseria meningitidis
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2003 2023
Mechanisms of Gonococcal Pilin Antigenic and Phase Variation
National Institute of Allergy and Infectious Diseases
2/1/18 → 1/31/23
Project: Research project
Fimbriae Proteins
Antigenic Variation
Gene Conversion
Bacterial Chromosomes
Conversion Disorder
Genetic Analysis of Beneficial Bacterial Colonization
University of Wisconsin-Madison, National Institute of General Medical Sciences
9/1/17 → 5/31/21
Project: Research project
Decapodiformes
Biofilms
Publications
Communication
Genes
Mechanisms of Gonococcal Pilin Antigenic and Phase Variation
National Institute of Allergy and Infectious Diseases
2/1/16 → 1/31/18
Project: Research project
Assembly and Function of the Gonococcal Pilus
National Institute of Allergy and Infectious Diseases
3/2/15 → 2/28/17
Project: Research project
Fimbriae Proteins
Peptidoglycan
Neisseria gonorrhoeae
Peptide Hydrolases
Neisseria
Cellular and Molecular Basis of Disease Training Program
Brickner, J. H., Brickner, J. H., Holmgren, R. A. & Seifert, H.
National Institute of General Medical Sciences
7/1/13 → 6/30/16
Project: Research project
Research Output 1984 2019
A double-strand break does not promote Neisseria gonorrhoeae pilin antigenic variation
Prister, L. L., Xu, J. & Steven Seifert, H., Jan 1 2019, In : Journal of bacteriology. 201, 13, e00256-19.Research output: Contribution to journal › Article
Fimbriae Proteins
Antigenic Variation
Neisseria gonorrhoeae
G-Quadruplexes
Genetic Suppression
Anti-psychotic drugs block meningococcal virulence
Seifert, H., Jun 1 2019, In : Nature Microbiology. 4, 6, p. 906-907 2 p.Research output: Contribution to journal › Article
Neisseria meningitidis
Virulence Factors
Virulence
Schizophrenia
Pharmaceutical Preparations
3
Citations
(Scopus)
Location, Location, Location—Commensalism, Damage and Evolution of the Pathogenic Neisseria
Seifert, H., Jul 26 2019, In : Journal of Molecular Biology. 431, 16, p. 3010-3014 5 p.Research output: Contribution to journal › Review article
Neisseria
Inflammation
Neisseria meningitidis
Virulence
Mouth
PacBio amplicon sequencing method to measure pilin antigenic variation frequencies of Neisseria gonorrhoeae
Ozer, E. A., Prister, L. L., Yin, S., Ward, B. H., Ivanov, S. & Seifert, H. S., Jan 1 2019, In : mSphere. 4, 5, e00562-19.Research output: Contribution to journal › Article
Open Access
Fimbriae Proteins
Antigenic Variation
Neisseria gonorrhoeae
Genes
Gene Conversion
1
Citation
(Scopus)
Transcriptional initiation of a small RNA, not R-loop stability, dictates the frequency of pilin antigenic variation in Neisseria gonorrhoeae
Prister, L. L., Ozer, E. A., Cahoon, L. A. & Seifert, H., Oct 1 2019, In : Molecular Microbiology. 112, 4, p. 1219-1234 16 p.Research output: Contribution to journal › Article
Fimbriae Proteins
Antigenic Variation
Neisseria gonorrhoeae
RNA
Chromatin Immunoprecipitation