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Hank Seifert

  • 5971 Citations
1984 …2020

Research output per year

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Personal profile

Research Interests

Neisseria gonorrhoeae, gonorrhea, Neisseria meningitidis, pilus, antigenic variation, recombination, DNA transformation, DNA replication, DNA repair, antioxidant functions, reactive oxygen species (ROS), neutrophil interactions. epithelium interactions

Education/Academic qualification

PhD, Pennsylvania State University

… → 1983

Research interests

  • DNA Recombination
  • DNA Repair
  • Genetics: Microbial
  • Genomics
  • Infectious Diseases: Bacteria
  • Inflammation
  • Microbial Pathogenesis
  • Microbiology

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Grants

Targeting the functions of the gonococcal Type lV pilus

Luan, C., Ozer, E. A. & Seifert, H.

National Institute of Allergy and Infectious Diseases

8/1/20 → 7/31/24

Project: Research project

    • An unbiased screen to identify Neisseria gonorrhoeae genes important for survival to neutrophil killing mechanisms

    Ozer, E. A. & Seifert, H.

    National Institute of Allergy and Infectious Diseases

    6/17/20 → 5/31/22

    Project: Research project

    • Mechanisms of Gonococcal Pilin Antigenic and Phase Variation

    Seifert, H.

    National Institute of Allergy and Infectious Diseases

    2/1/18 → 1/31/23

    Project: Research project

    • Genetic Analysis of Beneficial Bacterial Colonization

    Seifert, H.

    University of Wisconsin-Madison, National Institute of General Medical Sciences

    9/1/17 → 5/31/21

    Project: Research project

    • Mechanisms of Gonococcal Pilin Antigenic and Phase Variation

    Seifert, H.

    National Institute of Allergy and Infectious Diseases

    2/1/16 → 1/31/18

    Project: Research project

    Research Output

    • 5971 Citations
    • 125 Article
    • 8 Review article
    • 6 Comment/debate
    • 2 Short survey

    Altering the Neisseria gonorrhoeae pilE Guanine Quadruplex Loop Bases Affects Pilin Antigenic Variation

    Prister, L. L., Yin, S., Cahoon, L. A. & Seifert, H. S., Mar 17 2020, In : Biochemistry. 59, 10, p. 1104-1112 9 p.

    Research output: Contribution to journal › Article

    • 1 Scopus citations

    A double-strand break does not promote Neisseria gonorrhoeae pilin antigenic variation

    Prister, L. L., Xu, J. & Steven Seifert, H., Jan 1 2019, In : Journal of bacteriology. 201, 13, e00256-19.

    Research output: Contribution to journal › Article

    • Anti-psychotic drugs block meningococcal virulence

    Seifert, H., Jun 1 2019, In : Nature Microbiology. 4, 6, p. 906-907 2 p.

    Research output: Contribution to journal › Article

    • Gonorrhoea

    Unemo, M., Seifert, H. S., Hook, E. W., Hawkes, S., Ndowa, F. & Dillon, J. A. R., Dec 1 2019, In : Nature Reviews Disease Primers. 5, 1, 79.

    Research output: Contribution to journal › Article

    • 11 Scopus citations

    Location, Location, Location—Commensalism, Damage and Evolution of the Pathogenic Neisseria

    Seifert, H. S., Jul 26 2019, In : Journal of Molecular Biology. 431, 16, p. 3010-3014 5 p.

    Research output: Contribution to journal › Review article

    • 7 Scopus citations