• 5734 Citations
1984 …2023
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Personal profile

Research Interests

Neisseria gonorrhoeae, gonorrhea, Neisseria meningitidis, pilus, antigenic variation, recombination, DNA transformation, DNA replication, DNA repair, antioxidant functions, reactive oxygen species (ROS), neutrophil interactions. epithelium interactions

Education/Academic qualification

PhD, Pennsylvania State University

… → 1983

Research interests

  • DNA Recombination
  • DNA Repair
  • Genetics: Microbial
  • Genomics
  • Infectious Diseases: Bacteria
  • Inflammation
  • Microbial Pathogenesis
  • Microbiology

Fingerprint Dive into the research topics where Hank Seifert is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Neisseria gonorrhoeae Medicine & Life Sciences
Fimbriae Proteins Medicine & Life Sciences
Antigenic Variation Medicine & Life Sciences
Neisseria Medicine & Life Sciences
DNA Medicine & Life Sciences
Genetic Recombination Medicine & Life Sciences
Genes Medicine & Life Sciences
Neisseria meningitidis Medicine & Life Sciences

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Grants 2003 2023

Fimbriae Proteins
Antigenic Variation
Gene Conversion
Bacterial Chromosomes
Conversion Disorder
Decapodiformes
Biofilms
Publications
Communication
Genes
Fimbriae Proteins
Peptidoglycan
Neisseria gonorrhoeae
Peptide Hydrolases
Neisseria

Research Output 1984 2019

  • 5734 Citations
  • 124 Article
  • 8 Review article
  • 6 Comment/debate
  • 2 Short survey

A double-strand break does not promote Neisseria gonorrhoeae pilin antigenic variation

Prister, L. L., Xu, J. & Steven Seifert, H., Jan 1 2019, In : Journal of bacteriology. 201, 13, e00256-19.

Research output: Contribution to journalArticle

Fimbriae Proteins
Antigenic Variation
Neisseria gonorrhoeae
G-Quadruplexes
Genetic Suppression

Anti-psychotic drugs block meningococcal virulence

Seifert, H., Jun 1 2019, In : Nature Microbiology. 4, 6, p. 906-907 2 p.

Research output: Contribution to journalArticle

Neisseria meningitidis
Virulence Factors
Virulence
Schizophrenia
Pharmaceutical Preparations
3 Citations (Scopus)

Location, Location, Location—Commensalism, Damage and Evolution of the Pathogenic Neisseria

Seifert, H., Jul 26 2019, In : Journal of Molecular Biology. 431, 16, p. 3010-3014 5 p.

Research output: Contribution to journalReview article

Neisseria
Inflammation
Neisseria meningitidis
Virulence
Mouth

PacBio amplicon sequencing method to measure pilin antigenic variation frequencies of Neisseria gonorrhoeae

Ozer, E. A., Prister, L. L., Yin, S., Ward, B. H., Ivanov, S. & Seifert, H. S., Jan 1 2019, In : mSphere. 4, 5, e00562-19.

Research output: Contribution to journalArticle

Open Access
Fimbriae Proteins
Antigenic Variation
Neisseria gonorrhoeae
Genes
Gene Conversion
1 Citation (Scopus)

Transcriptional initiation of a small RNA, not R-loop stability, dictates the frequency of pilin antigenic variation in Neisseria gonorrhoeae

Prister, L. L., Ozer, E. A., Cahoon, L. A. & Seifert, H., Oct 1 2019, In : Molecular Microbiology. 112, 4, p. 1219-1234 16 p.

Research output: Contribution to journalArticle

Fimbriae Proteins
Antigenic Variation
Neisseria gonorrhoeae
RNA
Chromatin Immunoprecipitation