Hank Seifert

Professor, Microbiology-Immunology
J.E.Porter Professor in Biomed Res, Microbiology-Immunology
Driskill Graduate Training Program in Life Sciences
Member, CLP - Chemistry of Life Processes Institute
Member, NUANCE - Atomic and Nanoscale Characterization Experimental Center

https://orcid.org/0000-0001-8651-0375

Emailh-seifert@northwestern.edu

Source: Scopus

Research activity per year

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Personal profile

Research Interests

Neisseria gonorrhoeae, gonorrhea, Neisseria meningitidis, pilus, antigenic variation, recombination, DNA transformation, DNA replication, DNA repair, antioxidant functions, reactive oxygen species (ROS), neutrophil interactions. epithelium interactions

Education/Academic qualification

PhD, Pennsylvania State University

… → 1983

Research interests

DNA Recombination
DNA Repair
Genetics: Microbial
Genomics
Infectious Diseases: Bacteria
Inflammation
Microbial Pathogenesis
Microbiology

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5 Active
16 Finished

Targeting the functions of the gonococcal Type lV pilus
Seifert, H. & Ozer, E. A.
National Institute of Allergy and Infectious Diseases
8/1/20 → 7/31/24
Project: Research project
An unbiased screen to identify Neisseria gonorrhoeae genes important for survival to neutrophil killing mechanisms
Seifert, H. & Ozer, E. A.
National Institute of Allergy and Infectious Diseases
6/17/20 → 5/31/22
Project: Research project
Mechanisms of Gonococcal Pilin Antigenic and Phase Variation
Seifert, H.
National Institute of Allergy and Infectious Diseases
2/1/18 → 1/31/23
Project: Research project
NIAID Primary Caregiver Technical Assistance Supplement for Post-Doc Linda Hu in Mechanisms of Gonococcal Pilin Antigenic and Phase Variation
Seifert, H.
National Institute of Allergy and Infectious Diseases
2/1/18 → 1/31/23
Project: Research project
Genetic Analysis of Beneficial Bacterial Colonization
Seifert, H.
University of Wisconsin-Madison, National Institute of General Medical Sciences
9/1/17 → 5/31/21
Project: Research project

6287 Citations
126 Article
8 Review article
6 Comment/debate
2 Chapter
More
- 2 Short survey

Altering the Neisseria gonorrhoeae pilE Guanine Quadruplex Loop Bases Affects Pilin Antigenic Variation
Prister, L. L., Yin, S., Cahoon, L. A. & Seifert, H. S., Mar 17 2020, In: Biochemistry. 59, 10, p. 1104-1112 9 p.
Research output: Contribution to journal › Article › peer-review
1 Scopus citations
Discovery of a new neisseria gonorrhoeae type iv pilus assembly factor, tfpc
Hu, L. I., Yin, S., Ozer, E. A., Sewell, L., Rehman, S., Garnett, J. A. & Seifert, H. S., Sep 1 2020, In: mBio. 11, 5, p. 1-14 14 p., e02528-20.
Research output: Contribution to journal › Article › peer-review

Open Access
A double-strand break does not promote Neisseria gonorrhoeae pilin antigenic variation
Prister, L. L., Xu, J. & Steven Seifert, H., 2019, In: Journal of bacteriology. 201, 13, e00256-19.
Research output: Contribution to journal › Article › peer-review
Anti-psychotic drugs block meningococcal virulence
Seifert, H., Jun 1 2019, In: Nature Microbiology. 4, 6, p. 906-907 2 p.
Research output: Contribution to journal › Article › peer-review
Gonorrhoea
Unemo, M., Seifert, H. S., Hook, E. W., Hawkes, S., Ndowa, F. & Dillon, J. A. R., Dec 1 2019, In: Nature Reviews Disease Primers. 5, 1, 79.
Research output: Contribution to journal › Article › peer-review
32 Scopus citations