Grants per year
Personal profile
Research Interests
Neisseria gonorrhoeae, gonorrhea, Neisseria meningitidis, pilus, antigenic variation, recombination, DNA transformation, DNA replication, DNA repair, antioxidant functions, reactive oxygen species (ROS), neutrophil interactions. epithelium interactions
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Molecular Biology, Pennsylvania State University
… → 1983
Research interests keywords
- DNA Recombination
- DNA Repair
- Genetics: Microbial
- Genomics
- Infectious Diseases: Bacteria
- Inflammation
- Microbial Pathogenesis
- Microbiology
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Network
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Support of the 29th Annual Midwest Microbial Pathogenesis Conference (MMPC)
Satchell, K. J., Seifert, H. & Yap, M. F.
3/1/23 → 12/31/23
Project: Research project
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Ordered gene knockout libraries for Neisseria gonorrhoeae
National Institute of Allergy and Infectious Diseases
7/1/21 → 6/30/24
Project: Research project
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Targeting the functions of the gonococcal Type lV pilus
Seifert, H., Ozer, E. A. & Hu, L. I.
National Institute of Allergy and Infectious Diseases
8/1/20 → 7/31/24
Project: Research project
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Mechanisms of Gonococcal Pilin Antigenic and Phase Variation
National Institute of Allergy and Infectious Diseases
2/1/18 → 1/31/24
Project: Research project
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The Neisseria gonorrhoeae type IV pilus promotes resistance to hydrogen peroxide- and LL-37-mediated killing by modulating the availability of intracellular, labile iron
Hu, L. I., Stohl, E. A. & Seifert, H. S., Jun 2022, In: PLoS pathogens. 18, 6, e1010561.Research output: Contribution to journal › Article › peer-review
Open Access -
Challenges and controversies concerning neisseria gonorrhoeae-neutrophil interactions in pathogenesis
Criss, A. K., Genco, C. A., Gray-Owen, S. D., Jerse, A. E. & Seifert, H. S., 2021, In: mBio. 12, 3, e00721-21.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Altering the Neisseria gonorrhoeae pilE Guanine Quadruplex Loop Bases Affects Pilin Antigenic Variation
Prister, L. L., Yin, S., Cahoon, L. A. & Seifert, H. S., Mar 17 2020, In: Biochemistry. 59, 10, p. 1104-1112 9 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Discovery of a new neisseria gonorrhoeae type iv pilus assembly factor, tfpc
Hu, L. I., Yin, S., Ozer, E. A., Sewell, L., Rehman, S., Garnett, J. A. & Seifert, H. S., Sep 1 2020, In: mBio. 11, 5, p. 1-14 14 p., e02528-20.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
A double-strand break does not promote Neisseria gonorrhoeae pilin antigenic variation
Prister, L. L., Xu, J. & Steven Seifert, H., 2019, In: Journal of bacteriology. 201, 13, e00256-19.Research output: Contribution to journal › Article › peer-review
5 Scopus citations