Hau C. Kwaan

  • 9507 Citations
1956 …2019
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Research Output 1956 2019

2019
Thrombosis
Neoplasms
1 Citation (Scopus)
Open Access
Yin-Yang
Thrombosis
Neoplasms
5 Citations (Scopus)

Fibrin and fibrinolysis in cancer

Kwaan, H. C. & Lindholm, P. F., Jan 1 2019, In : Seminars in thrombosis and hemostasis. 45, 4, p. 413-422 10 p.

Research output: Contribution to journalArticle

Fibrinolysis
Fibrin
Neoplasms
Plasminogen Activator Inhibitor 1
Urokinase Plasminogen Activator Receptors
1 Citation (Scopus)

The Role of Abnormal Hemostasis and Fibrinolysis in Morbidity and Mortality of Acute Promyelocytic Leukemia

Kwaan, H. C., Weiss, I. & Tallman, M. S., Sep 1 2019, In : Seminars in thrombosis and hemostasis. 45, 6, p. 612-621 10 p.

Research output: Contribution to journalArticle

Acute Promyelocytic Leukemia
Fibrinolysis
Hemostasis
Fibrinolysin
Tissue Plasminogen Activator
2018
2 Citations (Scopus)

Complications of Implanted Nonbiologic Devices--An Overview

Kwaan, H. C., Feb 1 2018, In : Seminars in thrombosis and hemostasis. 44, 1, p. 7-11 5 p.

Research output: Contribution to journalReview article

Equipment and Supplies
Hemolysis
Thrombocytopenia
Blood Vessels
Thrombosis

Fatal massive hemolysis caused by immunoglobulin M anti-c antibody in a patient with newly diagnosed B-cell acute lymphoblastic leukemia: a case report

Galvez, C., Abutaleb, A., Iams, W. T., Lindholm, P. F. & Kwaan, H. C., Jun 2018, In : Clinical Case Reports. 6, 6, p. 1090-1093 4 p.

Research output: Contribution to journalArticle

Hemolysis
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Immunoglobulin M
B-Lymphocytes
Immunoglobulin G
1 Citation (Scopus)

Perturbation of Hemostatic Function by Nonbiologic Surfaces

Kwaan, H. C. & Teruya, J., Feb 1 2018, In : Seminars in thrombosis and hemostasis. 44, 1, p. 5-6 2 p.

Research output: Contribution to journalEditorial

Hemostatics
Thrombocytopenia
Liver Transplantation
Tissue Donors
Antibodies
Liver
36 Citations (Scopus)

Standardization of extracellular vesicle measurements by flow cytometry through vesicle diameter approximation

the ISTH-SSC-VB Working group, Jun 2018, In : Journal of Thrombosis and Haemostasis. 16, 6, p. 1236-1245 10 p.

Research output: Contribution to journalArticle

Flow Cytometry
Polystyrenes
Blood Platelets
Extracellular Vesicles
Calibration
2017
2 Citations (Scopus)

Fibrinolysis: Biochemistry, Clinical Aspects, and Therapeutic Potential

Kwaan, H., Lisman, T. & Medcalf, R. L., Mar 1 2017, In : Seminars in thrombosis and hemostasis. 43, 2, p. 113-114 2 p., 02414.

Research output: Contribution to journalArticle

Fibrinolysis
Biochemistry
Therapeutics
10 Citations (Scopus)

Microparticles and Fibrinolysis

Vallier, L., Cointe, S., Lacroix, R., Bonifay, A., Judicone, C., Dignat-George, F. & Kwaan, H. C., Mar 1 2017, In : Seminars in thrombosis and hemostasis. 43, 2, p. 129-134 6 p., 02362.

Research output: Contribution to journalArticle

Fibrinolysis
Fibrinolysin
Hemostasis
Blood Vessels
Homeostasis

Modulation of tumor matrix by components of the plasminogen-plasmin system

Kwaan, H. C., Jan 1 2017, Tumor Matrix Biology. CRC Press, p. 215-234 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Plasminogen
Fibrinolysin
Urokinase-Type Plasminogen Activator
Plasminogen Activator Inhibitor 1
Enzyme-Linked Immunosorbent Assay
4 Citations (Scopus)

Venous air embolism related to the use of central catheters revisited: with emphasis on dialysis catheters

Wong, S. S. M., Kwaan, H. C. & Ing, T. S., Dec 2017, In : Clinical Kidney Journal. 10, 6, p. 797-803 7 p.

Research output: Contribution to journalReview article

Air Embolism
Dialysis
Catheters
Nephrology
Air
2016

Abnormalities in the fibrinolysis pathway and clinical implications

Kwaan, H. C. & McMahon, B. J., Aug 24 2016, Nonmalignant Hematology: Expert Clinical Review: Questions and Answers. Springer International Publishing, p. 235-242 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Critical Pathways
Fibrinolysis
1 Citation (Scopus)

At the Crossroads of Transfusion Medicine and Hemostasis

Kwaan, H. C. & Ramsey, G., Feb 24 2016, In : Seminars in thrombosis and hemostasis. 42, 2, p. 93-94 2 p.

Research output: Contribution to journalEditorial

Transfusion Medicine
Hemostasis
Blood Transfusion
2015
33 Citations (Scopus)

Components of the plasminogen-plasmin system as biologic markers for cancer

McMahon, B. J. & Kwaan, H. C., Jan 1 2015, Advances in Experimental Medicine and Biology. Springer New York LLC, p. 145-156 12 p. (Advances in Experimental Medicine and Biology; vol. 867).

Research output: Chapter in Book/Report/Conference proceedingChapter

Plasminogen
Fibrinolysin
Plasminogen Activator Inhibitor 1
Biomarkers
Tumors
5 Citations (Scopus)

Hemostatic Dysfunction in Liver Diseases

Lisman, T. & Kwaan, H. C., Jul 22 2015, In : Seminars in Thrombosis and Hemostasis. 41, 5, p. 445-446 2 p.

Research output: Contribution to journalEditorial

Hemostatics
Hemostasis
Liver Diseases
6 Citations (Scopus)

Microparticle source and tissue factor expression in pregnancy

Wong, A. E., Kwaan, H. C., Grobman, W. A., Weiss, I. & Wong, C. A., Aug 1 2015, In : Annals of Hematology. 94, 8, p. 1285-1290 6 p.

Research output: Contribution to journalArticle

Thromboplastin
Trophoblasts
Pregnancy
Blood Platelets
Pregnant Women

Nitric oxide, coagulation and cancer

Derman, B. A., Kwaan, H. C., Elbatarny, M. & Othman, M., Jan 1 2015, Nitric Oxide and Cancer: Pathogenesis and Therapy. Springer International Publishing, p. 281-296 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Coagulation
Nitric Oxide
Neoplasms
Tumors
Nanotechnology
8 Citations (Scopus)

Risk Factors, Diagnosis, Management, and Outcome of Splanchnic Vein Thrombosis: A Retrospective Analysis

Derman, B. A. & Kwaan, H. C., Jun 16 2015, In : Seminars in thrombosis and hemostasis. 41, 5, p. 503-513 11 p., 02191.

Research output: Contribution to journalArticle

Viscera
Veins
Thrombosis
Budd-Chiari Syndrome
Portal Vein
12 Citations (Scopus)

The new or non-vitamin k antagonist oral anticoagulants: What have we learned since their debut

McMahon, B. J. & Kwaan, H. C., Jan 1 2015, In : Seminars in Thrombosis and Hemostasis. 41, 2, p. 188-194 7 p.

Research output: Contribution to journalArticle

Anticoagulants
Vitamin K
Intracranial Hemorrhages
Drug Design
Vulnerable Populations
2014
2 Citations (Scopus)

Age-related changes in thrombosis and hemostasis

Kwaan, H. C., McMahon, B. J. & Hylek, E. M., Sep 25 2014, In : Seminars in thrombosis and hemostasis. 40, 6, p. 619-620 2 p.

Research output: Contribution to journalEditorial

Age Factors
Hemostasis
Thrombosis
1 Citation (Scopus)

Cancer and thrombosis-an update

Kwaan, H. C., Apr 2014, In : Seminars in thrombosis and hemostasis. 40, 3, p. 275-276 2 p.

Research output: Contribution to journalEditorial

Thrombosis
Neoplasms
45 Citations (Scopus)

Desmopressin improves platelet activity in acute intracerebral hemorrhage.

Naidech, A. M., Maas, M. B., Levasseur-Franklin, K. E., Liotta, E. M., Guth, J. C., Berman, M., Rosenow, J. M., Lindholm, P. F., Bendok, B. R., Prabhakaran, S., Bernstein, R. A. & Kwaan, H. C., Aug 2014, In : Stroke; a journal of cerebral circulation. 45, 8, p. 2451-2453 3 p.

Research output: Contribution to journalArticle

Deamino Arginine Vasopressin
Cerebral Hemorrhage
Hematoma
Blood Platelets
von Willebrand Factor
8 Citations (Scopus)
Plasminogen
Fibrinolysin
Fibrinolysis
History
Growth
22 Citations (Scopus)

Internal tandem duplication of the FLT3 gene confers poor overall survival in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline-based chemotherapy: an International Consortium on Acute Promyelocytic Leukemia study

Lucena-Araujo, A. R., Kim, H. T., Jacomo, R. H., Melo, R. A., Bittencourt, R., Pasquini, R., Pagnano, K., Fagundes, E. M., Chauffaille, M. D. L., Chiattone, C. S., Lima, A. S., Ruiz-Argüelles, G., Undurraga, M. S., Martinez, L., Kwaan, H. C., Gallagher, R., Niemeyer, C. M., Schrier, S. L., Tallman, M. S., Grimwade, D. & 7 others, Ganser, A., Berliner, N., Ribeiro, R. C., Lo-Coco, F., Löwenberg, B., Sanz, M. A. & Rego, E. M., Jan 1 2014, In : Annals of Hematology. 93, 12, p. 2001-2010 10 p.

Research output: Contribution to journalArticle

fms-Like Tyrosine Kinase 3
Acute Promyelocytic Leukemia
Anthracyclines
Tretinoin
Drug Therapy

Meyer-Michel Samama, MD, PharmD (1927-2014)

Kwaan, H. C., Nov 1 2014, In : Seminars in thrombosis and hemostasis. 40, 8, 1 p.

Research output: Contribution to journalArticle

21st Century History
20th Century History
Venous Thromboembolism
Hematology
Hemostasis
8 Citations (Scopus)

Prognostic impact of KMT2E transcript levels on outcome of patients with acute promyelocytic leukaemia treated with all-trans retinoic acid and anthracycline-based chemotherapy: An International Consortium on Acute Promyelocytic Leukaemia study

Lucena-Araujo, A. R., Kim, H. T., Jacomo, R. H., Melo, R. A., Bittencourt, R., Pasquini, R., Pagnano, K., Fagundes, E. M., de Lourdes Chauffaille, M., Chiattone, C. S., Lima, A. S., Kwaan, H. C., Gallagher, R., Niemeyer, C. M., Schrier, S. L., Tallman, M. S., Grimwade, D., Ganser, A., Berliner, N., Ribeiro, R. C. & 4 others, Lo-Coco, F., Löwenberg, B., Sanz, M. A. & Rego, E. M., Jan 1 2014, In : British Journal of Haematology. 166, 4, p. 540-549 10 p.

Research output: Contribution to journalArticle

Acute Promyelocytic Leukemia
Anthracyclines
Tretinoin
Confidence Intervals
Drug Therapy
30 Citations (Scopus)

The coagulopathy in acute promyelocytic leukaemia - What have we learned in the past twenty years

Kwaan, H. C. & Cull, E. H., Mar 2014, In : Best Practice and Research: Clinical Haematology. 27, 1, p. 11-18 8 p.

Research output: Contribution to journalReview article

Acute Promyelocytic Leukemia
Pathology
Hemostatics
Hemorrhage
Cause of Death
11 Citations (Scopus)

The unique hemostatic dysfunction in acute promyelocytic leukemia

Kwaan, H. C., Apr 2014, In : Seminars in thrombosis and hemostasis. 40, 3, p. 332-336 5 p.

Research output: Contribution to journalArticle

Acute Promyelocytic Leukemia
Hemostatics
Tretinoin
Annexin A2
Granulocyte Precursor Cells
1 Citation (Scopus)

Thrombocytopenia in older adults

McMahon, B. J. & Kwaan, H. C., Sep 1 2014, In : Seminars in Thrombosis and Hemostasis. 40, 6, p. 682-687 6 p.

Research output: Contribution to journalArticle

Thrombocytopenia
Pharmaceutical Preparations
Hemorrhage
Comorbidity
Blood Platelets
2013
51 Citations (Scopus)

Administration of ATRA to newly diagnosed patients with acute promyelocytic leukemia is delayed contributing to early hemorrhagic death

Altman, J. K., Rademaker, A., Cull, E., Weitner, B. B., Ofran, Y., Rosenblat, T. L., Haidau, A., Park, J. H., Ram, S. L., Orsini, J. M., Sandhu, S., Catchatourian, R., Trifilio, S. M., Adel, N. G., Frankfurt, O., Stein, E. M., Mallios, G., Deblasio, T., Jurcic, J. G., Nimer, S. & 5 others, Peterson, L. A. C., Kwaan, H. C., Rowe, J. M., Douer, D. & Tallman, M. S., Sep 1 2013, In : Leukemia Research. 37, 9, p. 1004-1009 6 p.

Research output: Contribution to journalArticle

Acute Promyelocytic Leukemia
Tretinoin
Hemorrhage
Mortality
4 Citations (Scopus)

Biologic role of the plasminogen-plasmin system: Thrombolysis, bleeding, and beyond

Kwaan, H. & Mazar, A., Jun 3 2013, In : Seminars in thrombosis and hemostasis. 39, 4, p. 327-328 2 p.

Research output: Contribution to journalEditorial

Plasminogen
Fibrinolysin
Fibrinolysis
Hemorrhage
35 Citations (Scopus)

Hyperviscosity in plasma cell dyscrasias

Kwaan, H. C., Nov 25 2013, In : Clinical Hemorheology and Microcirculation. 55, 1, p. 75-83 9 p.

Research output: Contribution to journalReview article

Paraproteins
Paraproteinemias
Blood Viscosity
Immunoglobulin G
Immunoglobulin A
51 Citations (Scopus)

Improving acute promyelocytic leukemia (APL) outcome in developing countries through networking, results of the International Consortium on APL

Rego, E. M., Kim, H. T., Ruiz-Argüelles, G. J., Undurraga, M. S., Uriarte, M. D. R., Jacomo, R. H., Gutiérrez-Aguirre, H., Melo, R. A. M., Bittencourt, R., Pasquini, R., Pagnano, K., Fagundes, E. M., Chauffaille, M. D. L., Chiattone, C. S., Martinez, L., Meillón, L. A., Gómez-Almaguer, D., Kwaan, H. C., Garcés-Eisele, J., Gallagher, R. & 10 others, Niemeyer, C. M., Schrier, S. L., Tallman, M., Grimwade, D., Ganser, A., Berliner, N., Ribeiro, R. C., Lo-Coco, F., Löwenberg, B. & Sanz, M. A., Jan 1 2013, In : Blood. 121, 11, p. 1935-1943 9 p.

Research output: Contribution to journalArticle

Acute Promyelocytic Leukemia
Developing countries
Developing Countries
Chemotherapy
Disease-Free Survival
156 Citations (Scopus)

Standardization of pre-analytical variables in plasma microparticle determination: Results of the International Society on Thrombosis and Haemostasis SSC Collaborative workshop

Lacroix, R., Judicone, C., Mooberry, M., Boucekine, M., Key, N. S., Dignat-George, F., Ambrozic, A., Bailly, N., Buffat, C., Buzas, E., Charpentier, A., Chatelain, B., Dogne, J. M. D., Falanga, A., Garcia Arias-Salgado, E., Gyorgy, B., Harrison, M., Kwaan, H., Lakota, K., Latger-Cannard, V. & 12 others, Massin, F., Mobarrez, F., Mojca, F., Mullier, F., Phelan, J. P., Snoj, N., Sodin-Semrl, S., Stezpień, E., Susen, S., Terrisse, A. D., Tintillier, V. & Vignoli, A., Jun 1 2013, In : Journal of Thrombosis and Haemostasis. 11, 6, p. 1190-1193 4 p.

Research output: Contribution to journalArticle

Hemostasis
Thrombosis
Education
48 Citations (Scopus)

The apparent uPA/PAI-1 paradox in cancer: More than meets the eye

Kwaan, H. C., Mazar, A. P. & McMahon, B. J., Mar 29 2013, In : Seminars in thrombosis and hemostasis. 39, 4, p. 382-391 10 p.

Research output: Contribution to journalArticle

Plasminogen Activator Inhibitor 1
Plasminogen
Neoplasms
Fibrinolysin
Plasminogen Inactivators
10 Citations (Scopus)

Ticlopidine-associated ADAMTS13 activity deficient thrombotic thrombocytopenic purpura in 22 persons in Japan: A report from the Southern Network on Adverse Reactions (SONAR)

Bennett, C. L., Jacob, S., Dunn, B. L., Georgantopoulos, P., Zheng, X. L., Kwaan, H. C., Mckoy, J. M., Magwood, J. S., Qureshi, Z. P., Bandarenko, N., Winters, J. L., Raife, T. J., Carey, P. M., Sarode, R., Kiss, J. E., Danielson, C., Ortel, T. L., Clark, W. F., Ablin, R. J., Rock, G. & 2 others, Matsumoto, M. & Fujimura, Y., Jun 1 2013, In : British Journal of Haematology. 161, 6, p. 896-898 3 p.

Research output: Contribution to journalArticle

ADAM Proteins
Ticlopidine
Thrombotic Thrombocytopenic Purpura
Enzyme Activation
Japan
2012

Adverse effects of drugs on hemostasis and thrombosis

Kwaan, H. C. & Bennett, C. L., Nov 8 2012, In : Seminars in Thrombosis and Hemostasis. 38, 8, p. 755-758 4 p.

Research output: Contribution to journalReview article

Fibrinolytic Agents
Hemostasis
Thrombosis
Pharmaceutical Preparations
14 Citations (Scopus)

Delayed anithyroid drug-induced agranulocytosis

Mutharasan, P., Oatis, W., Kwaan, H. C. & Molitch, M. E., Jul 1 2012, In : Endocrine Practice. 18, 4

Research output: Contribution to journalArticle

Methimazole
Agranulocytosis
Antithyroid Agents
Graves Disease
Neutropenia
1 Citation (Scopus)

Early platelet transfusion improves platelet activity and may improve outcomes after intracerebral hemorrhage

Naidech, A. M., Liebling, S. M., Rosenberg, N. F., Lindholm, P. F., Batjer, H. H. & Kwaan, H. C., Aug 1 2012, In : Neurocritical Care. 17, 1, p. 156-157 2 p.

Research output: Contribution to journalLetter

Platelet Transfusion
Cerebral Hemorrhage
Blood Platelets
76 Citations (Scopus)

Early platelet transfusion improves platelet activity and may improve outcomes after intracerebral hemorrhage

Naidech, A. M., Liebling, S. M., Rosenberg, N. F., Lindholm, P. F., Bernstein, R. A., Batjer, H. H., Alberts, M. J. & Kwaan, H. C., Feb 1 2012, In : Neurocritical Care. 16, 1, p. 82-87 6 p.

Research output: Contribution to journalArticle

Platelet Transfusion
Cerebral Hemorrhage
Blood Platelets
Hemorrhage
Aspirin
62 Citations (Scopus)

Gain-of-function ADAMTS13 variants that are resistant to autoantibodies against ADAMTS13 in patients with acquired thrombotic thrombocytopenic purpura

Jian, C., Xiao, J., Gong, L., Skipwith, C. G., Jin, S. Y., Kwaan, H. C. & Zheng, X. L., Apr 19 2012, In : Blood. 119, 16, p. 3836-3843 8 p.

Research output: Contribution to journalArticle

Thrombospondin 1
Disintegrins
Metalloproteases
Autoantibodies
von Willebrand Factor
5 Citations (Scopus)

The impact of medical education and networking on the outcome of leukemia treatment in developing countries. The experience of International Consortium on Acute Promyelocytic Leukemia (IC-APL)

Rego, E. M., Kim, H. T., Ruiz-Argüelles, G. J., Uriarte, M. D. R., Jacomo, R. H., Gutiérrez-Aguirre, H., Melo, R. A. M., Bittencourt, R., Pasquini, R., Pagnano, K., Fagundes, E. M., Chauffaille, M. D. L., Chiattone, C., Martinez, L., Meillón, L. A., Gómez-Almaguer, D., Kwaan, H. C., Garcés-Eisele, J., Gallagher, R., Niemeyer, C. M. & 4 others, Lowenberg, B., Ribeiro, R., LoCoco, F. & Sanz, M. A., Apr 1 2012, In : Hematology. 17, SUPPL. 1

Research output: Contribution to journalArticle

Acute Promyelocytic Leukemia
Medical Education
Developing Countries
Leukemia
Tretinoin
5 Citations (Scopus)

Thrombotic and bleeding complications associated with chemotherapy

McMahon, B. J. & Kwaan, H. C., Oct 12 2012, In : Seminars in Thrombosis and Hemostasis. 38, 8, p. 808-817 10 p.

Research output: Contribution to journalArticle

Hemorrhage
Drug Therapy
Thrombosis
Neoplasms
Anticoagulants
41 Citations (Scopus)

Ticlopidine-, clopidogrel-, and prasugrel-associated thrombotic thrombocytopenic purpura: A 20-year review from the southern network on adverse reactions (SONAR)

Jacob, S., Dunn, B. L., Qureshi, Z. P., Bandarenko, N., Kwaan, H. C., Pandey, D. K., McKoy, J. M., Barnato, S. E., Winters, J. L., Cursio, J. F., Weiss, I., Raife, T. J., Carey, P. M., Sarode, R., Kiss, J. E., Danielson, C., Ortel, T. L., Clark, W. F., Rock, G., Matsumoto, M. & 7 others, Fujimura, Y., Zheng, X. L., Chen, H., Chen, F., Armstrong, J. M., Raisch, D. W. & Bennett, C. L., Oct 31 2012, In : Seminars in thrombosis and hemostasis. 38, 8, p. 845-853 9 p.

Research output: Contribution to journalReview article

clopidogrel
Ticlopidine
Thrombotic Thrombocytopenic Purpura
Thienopyridines
Thrombospondin 1
2011
5 Citations (Scopus)

Clinical roundtable monograph. Early death in patients with acute promyelocytic leukemia.

Tallman, M. S., Lo-Coco, F., Kwaan, H. C., Sanz, M. A. & Gore, S. D., Feb 1 2011, In : Clinical advances in hematology & oncology : H&O. 9, 2, p. 1-16 16 p.

Research output: Contribution to journalArticle

Acute Promyelocytic Leukemia
Tretinoin
Remission Induction
Anthracyclines
Cause of Death
13 Citations (Scopus)
Acute Promyelocytic Leukemia
Tretinoin
Remission Induction
Anthracyclines
Cause of Death
6 Citations (Scopus)

Infection and Anemia

Kwaan, H. C., Feb 9 2011, In : Infectious Disorders - Drug Targets. 11, 1, p. 40-44 5 p.

Research output: Contribution to journalArticle

Anemia
Infection
Hepcidins
Hemolytic Anemia
Erythrocytes

Infectious diseases and hematology: At the crossroad of contemporary therapy

Kwaan, H. C. & Ison, M. G., Feb 9 2011, In : Infectious Disorders - Drug Targets. 11, 1, p. 1-2 2 p.

Research output: Contribution to journalEditorial

Hematology
Communicable Diseases
Therapeutics