Hau C. Kwaan

  • 9554 Citations
1956 …2019

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2019

Fibrin and fibrinolysis in cancer

Kwaan, H. C. & Lindholm, P. F., Jan 1 2019, In : Seminars in thrombosis and hemostasis. 45, 4, p. 413-422 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

The Role of Abnormal Hemostasis and Fibrinolysis in Morbidity and Mortality of Acute Promyelocytic Leukemia

Kwaan, H. C., Weiss, I. & Tallman, M. S., Sep 1 2019, In : Seminars in thrombosis and hemostasis. 45, 6, p. 612-621 10 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Fatal massive hemolysis caused by immunoglobulin M anti-c antibody in a patient with newly diagnosed B-cell acute lymphoblastic leukemia: a case report

Galvez, C., Abutaleb, A., Iams, W. T., Lindholm, P. F. & Kwaan, H. C., Jun 2018, In : Clinical Case Reports. 6, 6, p. 1090-1093 4 p.

Research output: Contribution to journalArticle

Standardization of extracellular vesicle measurements by flow cytometry through vesicle diameter approximation

the ISTH-SSC-VB Working group, Jun 2018, In : Journal of Thrombosis and Haemostasis. 16, 6, p. 1236-1245 10 p.

Research output: Contribution to journalArticle

40 Scopus citations
2017

Fibrinolysis: Biochemistry, Clinical Aspects, and Therapeutic Potential

Kwaan, H., Lisman, T. & Medcalf, R. L., Mar 1 2017, In : Seminars in thrombosis and hemostasis. 43, 2, p. 113-114 2 p., 02414.

Research output: Contribution to journalArticle

3 Scopus citations

Microparticles and Fibrinolysis

Vallier, L., Cointe, S., Lacroix, R., Bonifay, A., Judicone, C., Dignat-George, F. & Kwaan, H. C., Mar 1 2017, In : Seminars in thrombosis and hemostasis. 43, 2, p. 129-134 6 p., 02362.

Research output: Contribution to journalArticle

12 Scopus citations
2015

Microparticle source and tissue factor expression in pregnancy

Wong, A. E., Kwaan, H. C., Grobman, W. A., Weiss, I. & Wong, C. A., Aug 1 2015, In : Annals of Hematology. 94, 8, p. 1285-1290 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Risk Factors, Diagnosis, Management, and Outcome of Splanchnic Vein Thrombosis: A Retrospective Analysis

Derman, B. A. & Kwaan, H. C., Jun 16 2015, In : Seminars in thrombosis and hemostasis. 41, 5, p. 503-513 11 p., 02191.

Research output: Contribution to journalArticle

8 Scopus citations

The new or non-vitamin k antagonist oral anticoagulants: What have we learned since their debut

McMahon, B. J. & Kwaan, H. C., Jan 1 2015, In : Seminars in Thrombosis and Hemostasis. 41, 2, p. 188-194 7 p.

Research output: Contribution to journalArticle

12 Scopus citations
2014

Desmopressin improves platelet activity in acute intracerebral hemorrhage.

Naidech, A. M., Maas, M. B., Levasseur-Franklin, K. E., Liotta, E. M., Guth, J. C., Berman, M., Rosenow, J. M., Lindholm, P. F., Bendok, B. R., Prabhakaran, S., Bernstein, R. A. & Kwaan, H. C., Aug 2014, In : Stroke; a journal of cerebral circulation. 45, 8, p. 2451-2453 3 p.

Research output: Contribution to journalArticle

47 Scopus citations
8 Scopus citations

Internal tandem duplication of the FLT3 gene confers poor overall survival in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline-based chemotherapy: an International Consortium on Acute Promyelocytic Leukemia study

Lucena-Araujo, A. R., Kim, H. T., Jacomo, R. H., Melo, R. A., Bittencourt, R., Pasquini, R., Pagnano, K., Fagundes, E. M., Chauffaille, M. D. L., Chiattone, C. S., Lima, A. S., Ruiz-Argüelles, G., Undurraga, M. S., Martinez, L., Kwaan, H. C., Gallagher, R., Niemeyer, C. M., Schrier, S. L., Tallman, M. S., Grimwade, D. & 7 others, Ganser, A., Berliner, N., Ribeiro, R. C., Lo-Coco, F., Löwenberg, B., Sanz, M. A. & Rego, E. M., Jan 1 2014, In : Annals of Hematology. 93, 12, p. 2001-2010 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Meyer-Michel Samama, MD, PharmD (1927-2014)

Kwaan, H. C., Nov 1 2014, In : Seminars in thrombosis and hemostasis. 40, 8, 1 p.

Research output: Contribution to journalArticle

Prognostic impact of KMT2E transcript levels on outcome of patients with acute promyelocytic leukaemia treated with all-trans retinoic acid and anthracycline-based chemotherapy: An International Consortium on Acute Promyelocytic Leukaemia study

Lucena-Araujo, A. R., Kim, H. T., Jacomo, R. H., Melo, R. A., Bittencourt, R., Pasquini, R., Pagnano, K., Fagundes, E. M., de Lourdes Chauffaille, M., Chiattone, C. S., Lima, A. S., Kwaan, H. C., Gallagher, R., Niemeyer, C. M., Schrier, S. L., Tallman, M. S., Grimwade, D., Ganser, A., Berliner, N., Ribeiro, R. C. & 4 others, Lo-Coco, F., Löwenberg, B., Sanz, M. A. & Rego, E. M., Jan 1 2014, In : British Journal of Haematology. 166, 4, p. 540-549 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

The unique hemostatic dysfunction in acute promyelocytic leukemia

Kwaan, H. C., Apr 2014, In : Seminars in thrombosis and hemostasis. 40, 3, p. 332-336 5 p.

Research output: Contribution to journalArticle

12 Scopus citations

Thrombocytopenia in older adults

McMahon, B. J. & Kwaan, H. C., Sep 1 2014, In : Seminars in Thrombosis and Hemostasis. 40, 6, p. 682-687 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
2013

Administration of ATRA to newly diagnosed patients with acute promyelocytic leukemia is delayed contributing to early hemorrhagic death

Altman, J. K., Rademaker, A., Cull, E., Weitner, B. B., Ofran, Y., Rosenblat, T. L., Haidau, A., Park, J. H., Ram, S. L., Orsini, J. M., Sandhu, S., Catchatourian, R., Trifilio, S. M., Adel, N. G., Frankfurt, O., Stein, E. M., Mallios, G., Deblasio, T., Jurcic, J. G., Nimer, S. & 5 others, Peterson, L. A. C., Kwaan, H. C., Rowe, J. M., Douer, D. & Tallman, M. S., Sep 1 2013, In : Leukemia Research. 37, 9, p. 1004-1009 6 p.

Research output: Contribution to journalArticle

51 Scopus citations

Improving acute promyelocytic leukemia (APL) outcome in developing countries through networking, results of the International Consortium on APL

Rego, E. M., Kim, H. T., Ruiz-Argüelles, G. J., Undurraga, M. S., Uriarte, M. D. R., Jacomo, R. H., Gutiérrez-Aguirre, H., Melo, R. A. M., Bittencourt, R., Pasquini, R., Pagnano, K., Fagundes, E. M., Chauffaille, M. D. L., Chiattone, C. S., Martinez, L., Meillón, L. A., Gómez-Almaguer, D., Kwaan, H. C., Garcés-Eisele, J., Gallagher, R. & 10 others, Niemeyer, C. M., Schrier, S. L., Tallman, M., Grimwade, D., Ganser, A., Berliner, N., Ribeiro, R. C., Lo-Coco, F., Löwenberg, B. & Sanz, M. A., Jan 1 2013, In : Blood. 121, 11, p. 1935-1943 9 p.

Research output: Contribution to journalArticle

51 Scopus citations

Standardization of pre-analytical variables in plasma microparticle determination: Results of the International Society on Thrombosis and Haemostasis SSC Collaborative workshop

Lacroix, R., Judicone, C., Mooberry, M., Boucekine, M., Key, N. S., Dignat-George, F., Ambrozic, A., Bailly, N., Buffat, C., Buzas, E., Charpentier, A., Chatelain, B., Dogne, J. M. D., Falanga, A., Garcia Arias-Salgado, E., Gyorgy, B., Harrison, M., Kwaan, H., Lakota, K., Latger-Cannard, V. & 12 others, Massin, F., Mobarrez, F., Mojca, F., Mullier, F., Phelan, J. P., Snoj, N., Sodin-Semrl, S., Stezpień, E., Susen, S., Terrisse, A. D., Tintillier, V. & Vignoli, A., Jun 1 2013, In : Journal of Thrombosis and Haemostasis. 11, 6, p. 1190-1193 4 p.

Research output: Contribution to journalArticle

161 Scopus citations

The apparent uPA/PAI-1 paradox in cancer: More than meets the eye

Kwaan, H. C., Mazar, A. P. & McMahon, B. J., Mar 29 2013, In : Seminars in thrombosis and hemostasis. 39, 4, p. 382-391 10 p.

Research output: Contribution to journalArticle

48 Scopus citations

Ticlopidine-associated ADAMTS13 activity deficient thrombotic thrombocytopenic purpura in 22 persons in Japan: A report from the Southern Network on Adverse Reactions (SONAR)

Bennett, C. L., Jacob, S., Dunn, B. L., Georgantopoulos, P., Zheng, X. L., Kwaan, H. C., Mckoy, J. M., Magwood, J. S., Qureshi, Z. P., Bandarenko, N., Winters, J. L., Raife, T. J., Carey, P. M., Sarode, R., Kiss, J. E., Danielson, C., Ortel, T. L., Clark, W. F., Ablin, R. J., Rock, G. & 2 others, Matsumoto, M. & Fujimura, Y., Jun 1 2013, In : British Journal of Haematology. 161, 6, p. 896-898 3 p.

Research output: Contribution to journalArticle

10 Scopus citations
2012

Delayed anithyroid drug-induced agranulocytosis

Mutharasan, P., Oatis, W., Kwaan, H. C. & Molitch, M. E., Jul 1 2012, In : Endocrine Practice. 18, 4

Research output: Contribution to journalArticle

15 Scopus citations

Early platelet transfusion improves platelet activity and may improve outcomes after intracerebral hemorrhage

Naidech, A. M., Liebling, S. M., Rosenberg, N. F., Lindholm, P. F., Bernstein, R. A., Batjer, H. H., Alberts, M. J. & Kwaan, H. C., Feb 1 2012, In : Neurocritical Care. 16, 1, p. 82-87 6 p.

Research output: Contribution to journalArticle

77 Scopus citations

Gain-of-function ADAMTS13 variants that are resistant to autoantibodies against ADAMTS13 in patients with acquired thrombotic thrombocytopenic purpura

Jian, C., Xiao, J., Gong, L., Skipwith, C. G., Jin, S. Y., Kwaan, H. C. & Zheng, X. L., Apr 19 2012, In : Blood. 119, 16, p. 3836-3843 8 p.

Research output: Contribution to journalArticle

63 Scopus citations

The impact of medical education and networking on the outcome of leukemia treatment in developing countries. The experience of International Consortium on Acute Promyelocytic Leukemia (IC-APL)

Rego, E. M., Kim, H. T., Ruiz-Argüelles, G. J., Uriarte, M. D. R., Jacomo, R. H., Gutiérrez-Aguirre, H., Melo, R. A. M., Bittencourt, R., Pasquini, R., Pagnano, K., Fagundes, E. M., Chauffaille, M. D. L., Chiattone, C., Martinez, L., Meillón, L. A., Gómez-Almaguer, D., Kwaan, H. C., Garcés-Eisele, J., Gallagher, R., Niemeyer, C. M. & 4 others, Lowenberg, B., Ribeiro, R., LoCoco, F. & Sanz, M. A., Apr 1 2012, In : Hematology. 17, SUPPL. 1

Research output: Contribution to journalArticle

5 Scopus citations

Thrombotic and bleeding complications associated with chemotherapy

McMahon, B. J. & Kwaan, H. C., Oct 12 2012, In : Seminars in Thrombosis and Hemostasis. 38, 8, p. 808-817 10 p.

Research output: Contribution to journalArticle

5 Scopus citations
2011

Clinical roundtable monograph. Early death in patients with acute promyelocytic leukemia.

Tallman, M. S., Lo-Coco, F., Kwaan, H. C., Sanz, M. A. & Gore, S. D., Feb 1 2011, In : Clinical advances in hematology & oncology : H&O. 9, 2, p. 1-16 16 p.

Research output: Contribution to journalArticle

5 Scopus citations
14 Scopus citations

Infection and Anemia

Kwaan, H. C., Feb 9 2011, In : Infectious Disorders - Drug Targets. 11, 1, p. 40-44 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

Microvascular thrombosis: A serious and deadly pathologic process in multiple diseases

Kwaan, H. C., Dec 1 2011, In : Seminars in thrombosis and hemostasis. 37, 8, p. 961-977 17 p.

Research output: Contribution to journalArticle

16 Scopus citations

Particulate matter-induced lung inflammation increases systemic levels of PAI-1 and activates coagulation through distinct mechanisms

Budinger, G. R. S., McKell, J. L., Urich, D., Foiles, N., Weiss, I., Chiarella, S. E., Gonzalez, A., Soberanes, S., Ghio, A. J., Nigdelioglu, R., Mutlu, E. A., Radigan, K. A., Green, D., Kwaan, H. C. & Mutlu, G. M., Apr 20 2011, In : PloS one. 6, 4, e18525.

Research output: Contribution to journalArticle

64 Scopus citations

The Pathophysiology of Coagulopathy in APL

Kwaan, H. C., Feb 1 2011, In : Clinical Advances in Hematology and Oncology. 9, 2, p. 7-9 3 p.

Research output: Contribution to journalArticle

1 Scopus citations
2010

Multiple domains of ADAMTS13 are targeted by autoantibodies against ADAMTS13 in patients with acquired idiopathic thrombotic thrombocytopenic purpura

Long Zheng, X., Wu, H. M., Shang, D., Falls, E., Skipwith, C. G., Cataland, S. R., Bennett, C. L. & Kwaan, H. C., Sep 1 2010, In : Haematologica. 95, 9, p. 1555-1562 8 p.

Research output: Contribution to journalArticle

76 Scopus citations

Role of plasma proteins in whole blood viscosity: A brief clinical review

Kwaan, H. C., 2010, In : Clinical Hemorheology and Microcirculation. 44, 3, p. 167-176 10 p.

Research output: Contribution to journalArticle

57 Scopus citations
2009
26 Scopus citations

Ticlopidine- and clopidogrel-associated thrombotic thrombocytopenic purpura (TTP): Review of clinical, laboratory, epidemiological, and pharmacovigilance findings (1989-2008)

Zakarija, A., Kwaan, H. C., Moake, J. L., Bandarenko, N., Pandey, D. K., McKoy, J. M., Yarnold, P. R., Raisch, D. W., Winters, J. L., Raife, T. J., Cursio, J. F., Luu, T. H., Richey, E. A., Fisher, M. J., Ortel, T. L., Tallman, M. S., Zheng, X. L., Matsumoto, M., Fujimura, Y. & Bennett, C. L., Feb 2009, In : Kidney international. 75, SUPPL. 112, p. S20-S24

Research output: Contribution to journalArticle

65 Scopus citations
2007

Pancreatitis preceding acute episodes of thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: Report of five patients with a systematic review of published reports

Swisher, K. K., Doan, J. T., Vesely, S. K., Kwaan, H. C., Kim, B., Lämmle, B., Hovinga, J. A. K. & George, J. N., Jul 1 2007, In : Haematologica. 92, 7, p. 936-943 8 p.

Research output: Contribution to journalArticle

53 Scopus citations

The life and vision of a pioneer: a tribute to Tage Astrup, D.Sc., Dr.Med.h.c.

Kwaan, H. C., Jun 2007, In : Seminars in thrombosis and hemostasis. 33, 4, p. 299-300 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

Two Mechanistic Pathways for Thienopyridine-Associated Thrombotic Thrombocytopenic Purpura. A Report From the SERF-TTP Research Group and the RADAR Project

Bennett, C. L., Kim, B., Zakarija, A., Bandarenko, N., Pandey, D. K., Buffie, C. G., McKoy, J. M., Tevar, A. D., Cursio, J. F., Yarnold, P. R., Kwaan, H. C., De Masi, D., Sarode, R., Raife, T. J., Kiss, J. E., Raisch, D. W., Davidson, C., Sadler, J. E., Ortel, T. L., Zheng, X. L. & 4 others, Kato, S., Matsumoto, M., Uemura, M. & Fujimura, Y., Sep 18 2007, In : Journal of the American College of Cardiology. 50, 12, p. 1138-1143 6 p.

Research output: Contribution to journalArticle

55 Scopus citations
2005

Meeting report

Tallman, M. S., Brenner, B., De La Serna, J., Dombret, H., Falanga, A., Kwaan, H. C., Liebman, H., Raffoux, E. & Rickles, F. R., Mar 1 2005, In : Leukemia Research. 29, 3, p. 347-351 5 p.

Research output: Contribution to journalArticle

49 Scopus citations
2004

Clopidogrel-Associated TTP An Update of Pharmacovigilance Efforts Conducted by Independent Researchers, Pharmaceutical Suppliers, and the Food and Drug Administration

Zakarija, A., Bandarenko, N., Pandey, D. K., Auerbach, A., Raisch, D. W., Kim, B., Kwaan, H. C., McKoy, J. M., Schmitt, B. P., Davidson, C. J., Yarnold, P. R., Gorelick, P. B. & Bennett, C. L., Feb 1 2004, In : Stroke. 35, 2, p. 533-537 5 p.

Research output: Contribution to journalArticle

82 Scopus citations

Effects of all-trans retinoic acid or chemotherapy on the molecular regulation of systemic blood coagulation and fibrinolysis in patients with acute promyelocytic leukemia

Tallman, M. S., Lefèbvre, P., Baine, R. M., Shoji, M., Cohen, I., Green, D., Kwaan, H. C., Paietta, E. & Rickles, F. R., Aug 1 2004, In : Journal of Thrombosis and Haemostasis. 2, 8, p. 1341-1350 10 p.

Research output: Contribution to journalArticle

102 Scopus citations

Expression of receptors for plasminogen activators on endothelial cell surface depends on their origin

Kwaan, H. C., Wang, J. & Weiss, I., Feb 1 2004, In : Journal of Thrombosis and Haemostasis. 2, 2, p. 306-312 7 p.

Research output: Contribution to journalArticle

35 Scopus citations

The thrombogenic effect of an inflammatory cytokine on trophoblasts from women with preeclampsia

Kwaan, H. C., Wang, J., Boggio, L., Weiss, I. & Grobman, W. A., Dec 1 2004, In : American journal of obstetrics and gynecology. 191, 6, p. 2142-2147 6 p.

Research output: Contribution to journalArticle

8 Scopus citations
2003

Dissemination of information on potentially fatal adverse drug reactions for cancer drugs from 2000 to 2002: First results from the research on adverse drug events and reports project

Ladewski, L. A., Belknap, S. M., Nebeker, J. R., Sartor, O., Lyons, E. A., Kuzel, T. C., Tallman, M. S., Raisch, D. W., Auerbach, A. R., Schumock, G. T., Kwaan, H. C. & Bennett, C. L., Oct 15 2003, In : Journal of Clinical Oncology. 21, 20, p. 3859-3866 8 p.

Research output: Contribution to journalArticle

61 Scopus citations
2002

Thalidomide-associated deep vein thrombosis and pulmonary embolism

Bennett, C. L., Schumock, G. T., Desai, A. A., Kwaan, H. C., Raisch, D. W., Newlin, R. & Stadler, W., Nov 1 2002, In : American Journal of Medicine. 113, 7, p. 603-606 4 p.

Research output: Contribution to journalArticle

69 Scopus citations

TTP/HUS occurring in a simultaneous pancreas/kidney transplant recipient after clopidogrel treatment: Evidence of a nonimmunologic etiology

Evens, A. M., Kwaan, H. C., Kaufman, D. B. & Bennett, C. L., Sep 27 2002, In : Transplantation. 74, 6, p. 885-887 3 p.

Research output: Contribution to journalArticle

31 Scopus citations
2001

The pathogenetic role of apoptosis in hypercoagulable states

Wang, J. & Kwaan, H. C., Jan 1 2001, In : Hematology. 6, 2, p. 143-152 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Thrombogenic role of cells undergoing apoptosis

Wang, J., Weiss, I., Svoboda, K. & Kwaan, H. C., Dec 1 2001, In : British Journal of Haematology. 115, 2, p. 382-391 10 p.

Research output: Contribution to journalArticle

77 Scopus citations