Grants per year
Personal profile
Research Interests
Herbert Y. Meltzer, MD, is Professor of Psychiatry and Behavioral Sciences, Pharmacology and Physiology and Director of the Translational Neuropharmacology Program at Northwestern University in Chicago, IL. He received his BA from Cornell University, an MA in Chemistry from Harvard, and his MD from Yale University. Dr. Meltzer has been President of the American College of Neuropsychopharmacology (ACNP) and the Collegium International Neuro-psychopharmacologicum (CINP). He was co-editor of the ACNP journal, Neuropsychopharmacology. Current research interests include: 1) development of novel drugs for treatment and prevention of psychosis, depression, opioid abuse, and age associated cognitive impairment; 2) behavioral and neurochemical studies of antipsychotic, antidepressant, cognitive improving, and antisuicide drugs; and 3) genetic biomarkers. Dr. Meltzer is the recipient of the Efron and Paul Hoch Awards of the ACNP, the Lieber Prize for Schizophrenia Research from NARSAD/Brain Behavior Research Foundation, the Dean Award for Research in Schizophrenia of the American College of Psychiatry, the Gold Medal Award of the Society of Biological Psychiatry, the Sutherland Prize for Research and Grant Liddle Award for Clinical Research of Vanderbilt University, the Research Prize of the American Psychiatric Association, and the Lifetime Achievement awards from the Schizophrenia International Research Society (SIRS).
Training Experience
1964 | Internship, Saint Luke's Hospital |
1966 | Residency, Massachusetts Mental Health Center |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
MD, Medicine, Yale University
… → 1963
Research interests keywords
- Clinical Research
- Depression
- Mental Health
- Neuropsychology
- Pharmacology
- Physiology
- Psychiatry
- Schizophrenia
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Collaborations and top research areas from the last five years
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Analysis of Apoaequorin as a Therapeutic Agent for Schizoprenia, Depression, and Cognitive Decline
Meltzer, H. Y., Huang, M. & Rajagopal, L.
8/7/20 → 8/6/25
Project: Research project
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Prot #IS00011961: The Mechanism Of ST100021 On Neurotransmitter Efflux Related To Psychosis
Dainippon Sumitomo Pharma Co., Ltd.
5/19/20 → 5/18/21
Project: Research project
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Prot #SCZD-0001: A Pilot Study of Digital Health Technology Assessments in Schizophrenia
PRA Health Sciences, Millennium Pharmaceuticals, Inc
2/13/19 → 2/13/22
Project: Research project
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Studies to Investigate the Mechanism of Action of Sunovion Compound SEP-856
Meltzer, H. Y., Huang, M. & Rajagopal, L.
4/26/18 → 4/26/19
Project: Research project
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Prot #SNR-05: An Adaptive, Phase II/III, Double-Blind, Randomized, Placebo-Controlled, Two-Part, Dose-Finding, Multi-Center Study of the Safety and Efficacy of NaBen® (Sodium Benzoate), a D-Amino Acid Oxidase Inhibitor, as an Add-on Therapy with Clozapine
Meltzer, H. Y. & Meriden, Z.
Amarex Clinical Research, SyneuRx International (Taiwan) Corp.
3/14/18 → 3/14/21
Project: Research project
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Long-Term Outcome of Clozapine in Treatment-Resistant Schizophrenia
Lee, M. A., Cola, P., Jayathilake, K. & Meltzer, H. Y., May 1 2023, In: Journal of clinical psychopharmacology. 43, 3, p. 211-219 9 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Neuroendocrine Studies in Psychiatric Disorders: The Role of Serotonin
Frank Nash, J. & Meltzer, H. Y., Jan 1 2023, The Role of Serotonin in Psychiatric Disorders. Taylor and Francis, p. 57-90 34 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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NU-1223, a simplified analog of alstonine, with 5-HT2cR agonist-like activity, rescues memory deficit and positive and negative symptoms in subchronic phencyclidine mouse model of schizophrenia
Rajagopal, L., Mahjour, S., Huang, M., Ryan, C. A., Elzokaky, A., Csakai, A. J., Orr, M. J., Scheidt, K. & Meltzer, H. Y., Oct 2 2023, In: Behavioural Brain Research. 454, 114614.Research output: Contribution to journal › Article › peer-review
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Polygenic risk scores analyses of psychiatric and metabolic traits with antipsychotic-induced weight gain in schizophrenia: an exploratory study
Yoshida, K., Marshe, V. S., Elsheikh, S. S. M., Maciukiewicz, M., Tiwari, A. K., Brandl, E. J., Lieberman, J. A., Meltzer, H. Y., Kennedy, J. L. & Müller, D. J., Sep 2023, In: Pharmacogenomics Journal. 23, 5, p. 119-126 8 p.Research output: Contribution to journal › Article › peer-review
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Awareness of illness moderates self-assessment of psychotic symptoms
Martinez Agulleiro, L., de Filippis, R., Rosson, S., Patil, B., Prizgint, L., Talasazan, N., Meltzer, H. Y., Kane, J. M., Gibbons, R. D. & Guinart, D., Oct 2022, In: Australian and New Zealand Journal of Psychiatry. 56, 10, p. 1287-1294 8 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations
Datasets
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CCDC 1030168: Experimental Crystal Structure Determination
Younai, A. (Contributor), Zeng, B. (Contributor), Meltzer, H. Y. (Contributor) & Scheidt, K. A. (Contributor), Cambridge Crystallographic Data Centre, 2015
DOI: 10.5517/cc13kz7w, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc13kz7w&sid=DataCite
Dataset
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Association of orexin receptor polymorphisms with antipsychotic-induced weight gain
Tiwari, A. K. (Creator), Brandl, E. J. (Creator), Zai, C. C. (Creator), Goncalves, V. F. (Creator), Chowdhury, N. I. (Creator), Freeman, N. (Creator), Lieberman, J. A. (Creator), Meltzer, H. Y. (Creator), Kennedy, J. L. (Creator) & Müller, D. J. (Creator), figshare, 2015
DOI: 10.6084/m9.figshare.1569415.v1, https://figshare.com/articles/Association_of_orexin_receptor_polymorphisms_with_antipsychotic_induced_weight_gain/1569415/1
Dataset
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Awareness of illness moderates self-assessment of psychotic symptoms
Martinez Agulleiro, L. (Creator), de Filippis, R. (Creator), Rosson, S. (Creator), Patil, B. (Creator), Prizgint, L. (Creator), Talasazan, N. (Creator), Meltzer, H. Y. (Creator), Kane, J. M. (Creator), Gibbons, R. D. (Creator) & Guinart, D. (Creator), SAGE Journals, 2021
DOI: 10.25384/sage.c.5713265.v1, https://sage.figshare.com/collections/Awareness_of_illness_moderates_self-assessment_of_psychotic_symptoms/5713265/1
Dataset
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Supplementary Material for: Fat Mass- and Obesity-Associated (FTO) Gene and Antipsychotic-Induced Weight Gain: An Association Study
Shing, E. C. (Creator), Tiwari, A. K. (Creator), Brandl, E. J. (Creator), Zai, C. C. (Creator), Lieberman, J. A. (Creator), Meltzer, H. Y. (Creator), Kennedy, J. L. (Creator), Müller, D. J. (Creator), Zai, C. C. (Creator) & Meltzer, H. Y. (Creator), Karger Publishers, 2014
DOI: 10.6084/m9.figshare.5125795.v1, https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Fat_Mass-_and_Obesity-Associated_FTO_Gene_and_Antipsychotic-Induced_Weight_Gain_An_Association_Study/5125795/1
Dataset
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CCDC 1040072: Experimental Crystal Structure Determination
Younai, A. (Contributor), Zeng, B. (Contributor), Meltzer, H. Y. (Contributor) & Scheidt, K. A. (Contributor), Cambridge Crystallographic Data Centre, 2015
DOI: 10.5517/cc13x8q0, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc13x8q0&sid=DataCite
Dataset