Herbert Y Meltzer

  • 68661 Citations
1961 …2022
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Research Output 1961 2019

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Review article
Review article
113 Citations (Scopus)

ACNP task force report on SSRIs and suicidal behavior in youth

Mann, J. J., Emslie, G., Baldessarini, R. J., Beardslee, W., Fawcett, J. A., Goodwin, F. K., Leon, A. C., Meltzer, H. Y., Ryan, N. D., Shaffer, D. & Wagner, K. D., Mar 1 2006, In : Neuropsychopharmacology. 31, 3, p. 473-492 20 p.

Research output: Contribution to journalReview article

Serotonin Uptake Inhibitors
Advisory Committees
Suicide
Antidepressive Agents
Depression
102 Citations (Scopus)

Adverse effects of the atypical antipsychotics

Meltzer, H. Y., Oct 5 1998, In : Journal of Clinical Psychiatry. 59, SUPPL. 12, p. 17-22 6 p.

Research output: Contribution to journalReview article

Antipsychotic Agents
Clozapine
Cholinergic Antagonists
Weight Gain
Orthostatic Hypotension
69 Citations (Scopus)

Adverse events related to olanzapine

Conley, R. R. & Meltzer, H. Y., May 22 2000, In : Journal of Clinical Psychiatry. 61, SUPPL. 8, p. 26-30 5 p.

Research output: Contribution to journalReview article

olanzapine
Antipsychotic Agents
Schizophrenia
Psychomotor Agitation
Serotonin Antagonists
434 Citations (Scopus)

A meta-analysis of neuropsychological change to clozapine, olanzapine, quetiapine, and risperidone in schizophrenia

Woodward, N. D., Purdon, S. E., Meltzer, H. Y. & Zald, D. H., Sep 1 2005, In : International Journal of Neuropsychopharmacology. 8, 3, p. 457-472 16 p.

Research output: Contribution to journalReview article

olanzapine
Risperidone
Clozapine
Antipsychotic Agents
Meta-Analysis
163 Citations (Scopus)

Antipsychotic drugs: Comparison in animal models of efficacy, neurotransmitter regulation, and neuroprotection

Lieberman, J. A., Bymaster, F. P., Meltzer, H. Y., Deutch, A. Y., Duncan, G. E., Marx, C. E., Aprille, J. R., Dwyer, D. S., Li, X. M., Mahadik, S. P., Duman, R. S., Porter, J. H., Modica-Napolitano, J. S., Newton, S. S. & Csernansky, J. G., Sep 1 2008, In : Pharmacological Reviews. 60, 3, p. 358-403 46 p.

Research output: Contribution to journalReview article

Antipsychotic Agents
Neurotransmitter Agents
Animal Models
Schizophrenia
Aptitude
31 Citations (Scopus)

Antipsychotic drugs in bipolar disorder

Ertugrul, A. & Meltzer, H. Y., Sep 1 2003, In : International Journal of Neuropsychopharmacology. 6, 3, p. 277-284 8 p.

Research output: Contribution to journalReview article

Bipolar Disorder
Antipsychotic Agents
olanzapine
Risperidone
Clozapine
45 Citations (Scopus)

Assessing cardiovascular risks versus clinical benefits of atypical antipsychotic drug treatment.

Meltzer, H. Y., Davidson, M., Glassman, A. H. & Vieweg, W. V. R., Jan 1 2002, In : The Journal of clinical psychiatry. 63 Suppl 9, p. 25-29 5 p.

Research output: Contribution to journalReview article

Antipsychotic Agents
Torsades de Pointes
Therapeutics
Sudden Death
Hypoglycemia
40 Citations (Scopus)

Assessing the effects of atypical antipsychotics on negative symptoms

Meltzer, H. Y., Oct 5 1998, In : Journal of Clinical Psychiatry. 59, SUPPL. 12, p. 28-34 7 p.

Research output: Contribution to journalReview article

Antipsychotic Agents
Schizophrenia
Depression
36 Citations (Scopus)

Assessment of EPS and tardive dyskinesia in clinical trials

Meltzer, H. Y., Oct 5 1998, In : Journal of Clinical Psychiatry. 59, SUPPL. 12, p. 23-27 5 p.

Research output: Contribution to journalReview article

Symptom Assessment
Antipsychotic Agents
Clinical Trials
Psychomotor Agitation
Dystonia
6 Citations (Scopus)

Attention must be paid: The association of plasma clozapine/NDMC ratio With working memory

Meltzer, H. Y., Jun 1 2015, In : American Journal of Psychiatry. 172, 6, p. 502-504 3 p.

Research output: Contribution to journalReview article

Clozapine
Short-Term Memory
9 Citations (Scopus)

Attention must be paid: The association of plasma clozapine/NDMC ratio With working memory

Meltzer, H. Y., Jun 1 2015, In : American Journal of Psychiatry. 172, 6, p. 502-504 3 p.

Research output: Contribution to journalReview article

Clozapine
Short-Term Memory
Psychotic Disorders
Schizophrenia
50 Citations (Scopus)

Atypical antipsychotics for treatment of depression in schizophrenia and affective disorders

Meltzer, H. Y., Oct 5 1998, In : Journal of Clinical Psychiatry. 59, SUPPL. 12, p. 41-45 5 p.

Research output: Contribution to journalReview article

Mood Disorders
Antipsychotic Agents
Schizophrenia
Depression
Suicide
20 Citations (Scopus)

Augmentation of antipsychotic drug action by azapirone 5-HT1A receptor partial agonists: A meta-analysis

Kishi, T., Meltzer, H. Y. & Iwata, N., Jul 1 2013, In : International Journal of Neuropsychopharmacology. 16, 6, p. 1259-1266 8 p.

Research output: Contribution to journalReview article

Receptor, Serotonin, 5-HT1A
Antipsychotic Agents
Serotonin 5-HT1 Receptor Agonists
Meta-Analysis
Confidence Intervals
12 Citations (Scopus)

Azapirone 5-HT1A receptor partial agonist treatment for major depressive disorder: Systematic review and meta-analysis

Kishi, T., Meltzer, H. Y., Matsuda, Y. & Iwata, N., Jan 1 2014, In : Psychological Medicine. 44, 11, p. 2255-2269 15 p.

Research output: Contribution to journalReview article

Serotonin 5-HT1 Receptor Agonists
Receptor, Serotonin, 5-HT1A
Major Depressive Disorder
Meta-Analysis
Placebos
9 Citations (Scopus)

Biochemical studies in schizophrenia

Meltzer, H. Y., Jan 1 1976, In : Schizophrenia bulletin. 2, 1, p. 10-18 9 p.

Research output: Contribution to journalReview article

Schizophrenia
Monoamine Oxidase
Acute-Phase Reaction
Hemolysin Proteins
Disease Susceptibility
20 Citations (Scopus)

Clinical development of atypical antipsychotics: Research design and evaluation

Meltzer, H. Y., Oct 5 1998, In : Journal of Clinical Psychiatry. 59, SUPPL. 12, p. 10-16 7 p.

Research output: Contribution to journalReview article

Antipsychotic Agents
Research Design
Clinical Trials
Investigational New Drug Application
Product Labeling
109 Citations (Scopus)

Clozapine: Balancing safety with superior antipsychotic efficacy

Meltzer, H. Y., Oct 1 2012, In : Clinical Schizophrenia and Related Psychoses. 6, 3, p. 134-144 11 p.

Research output: Contribution to journalReview article

Clozapine
Antipsychotic Agents
Safety
Schizophrenia
Agranulocytosis
67 Citations (Scopus)

Dexamethasone bioavailability: Implications for DST research

Lowy, M. T. & Meltzer, H. Y., Jan 1 1987, In : Biological psychiatry. 22, 3, p. 373-385 13 p.

Research output: Contribution to journalReview article

Dexamethasone
Biological Availability
Research
Serum
Psychiatry
224 Citations (Scopus)

Dimensions of outcome with clozapine

Meltzer, H. Y., Jan 1 1992, In : British Journal of Psychiatry. 160, MAY. SUPPL. 17, p. 46-53 8 p.

Research output: Contribution to journalReview article

Clozapine
Patient Readmission
Cost Savings
Semantics
Health Care Costs

Dimensions of outcome with clozapine.

Meltzer, H. Y., May 1 1992, In : The British journal of psychiatry. Supplement. 17, p. 46-53 8 p.

Research output: Contribution to journalReview article

Clozapine
Patient Readmission
Cost Savings
Semantics
Health Care Costs
6 Citations (Scopus)

Diretrizes da Federação Mundial das Sociedades de Psiquiatria Biológica para o tratamento biológico da esquizofrenia parte 1: Tratamento agudo

Translated title of the contribution: World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for biological treatment of schizophrenia part 1: Acute treatmentFalkai, P., Wobrock, T., Lieberman, J., Glenthoj, B., Gattaz, W. F., Möller, H. J., Altamura, A. C., Andreasen, N., Barnes, T. R. E., Beckmann, H., Ciprian-Ollivier, J., Crow, T., David, A., Davidson, M., Deakin, B., Elkis, H., Farde, L., Gaebel, W., Gallhofer, B., Gerlach, J. & 17 others, Hirsch, S. R., Hojaij, C. R., Jablensky, A., Kane, J., Kojima, T., Von Knorring, L., McGorry, P., Meltzer, H., Moussaoui, D., Müller-Spahn, F., Olie, J. P., Palha, A. P., Sato, M., Sauer, H., Schooler, N., Weinberger, D. & Yamawaki, S., Dec 1 2006, In : Revista de Psiquiatria Clinica. 33, SUPPL. 1, p. 7-64 58 p.

Research output: Contribution to journalReview article

Biological Psychiatry
Schizophrenia
Guidelines
Therapeutics
Pharmacology
4 Citations (Scopus)

Diretrizes da Federação Mundial das Sociedades de Psiquiatria Biológica para o tratamento biológico da esquizofrenia parte 2: Tratamento de longo prazo

Translated title of the contribution: World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for biological treatment of schizophrenia part 2: Long-term treatmentFalkai, P., Wobrock, T., Lieberman, J., Glenthoj, B., Gattaz, W. F., Möller, H. J., Altamura, A. C., Andreasen, N., Barnes, T. R. E., Beckmann, H., Ciprian-Ollivier, J., Crow, T., David, A., Davidson, M., Deakin, B., Elkis, H., Farde, L., Gaebel, W., Gallhofer, B., Gerlach, J. & 17 others, Hirsch, S. R., Hojaij, C. R., Jablensky, A., Kane, J., Kojima, T., Von Knorring, L., McGorry, P., Meltzer, H., Moussaoui, D., Müller-Spahn, F., Olie, J. P., Palha, A. P., Sato, M., Sauer, H., Schooler, N., Weinberger, D. & Yamawaki, S., Dec 1 2006, In : Revista de Psiquiatria Clinica. 33, SUPPL. 1, p. 65-100 36 p.

Research output: Contribution to journalReview article

Biological Psychiatry
Schizophrenia
Guidelines
Therapeutics
Pharmacology
119 Citations (Scopus)

Does stimulation of 5-HT1A receptors improve cognition in schizophrenia?

Meltzer, H. Y. & Sumiyoshi, T., Dec 16 2008, In : Behavioural Brain Research. 195, 1, p. 98-102 5 p.

Research output: Contribution to journalReview article

Receptor, Serotonin, 5-HT1A
Cognition
Schizophrenia
Serotonin 5-HT1 Receptor Agonists
Antipsychotic Agents
9 Citations (Scopus)

Dopaminergic and serotonergic control of neuroendocrine function.

Gudelsky, G. A., Simonovic, M. & Meltzer, H. Y., Jan 1 1984, In : Monographs in neural sciences. 10, p. 85-102 18 p.

Research output: Contribution to journalReview article

Methyltyrosines
Tetrahydronaphthalenes
Piperidines
Benzamides
Hypothalamo-Hypophyseal System
4 Citations (Scopus)

Effect of benzamide drugs on prolactin secretion: relation to the dopamine receptor.

Meltzer, H. Y., So, R. & Fang, V. S., Dec 1 1982, In : Advances in biochemical psychopharmacology. 35, p. 61-82 22 p.

Research output: Contribution to journalReview article

Benzamides
Sulpiride
Dopamine Receptors
Pituitary Gland
Prolactin
65 Citations (Scopus)

Effect of serotonin precursors and serotonin agonists on plasma hormone levels.

Meltzer, H. Y., Wiita, B., Tricou, B. J., Simonovic, M., Fang, V. & Manov, G., Jan 1 1982, In : Advances in biochemical psychopharmacology. 34, p. 117-139 23 p.

Research output: Contribution to journalReview article

5-Hydroxytryptophan
Serotonin Receptor Agonists
Pituitary Gland
Prolactin
Growth Hormone
33 Citations (Scopus)

Evaluating the effects of antipsychotics on cognition in schizophrenia

Meltzer, H. Y., Oct 5 1998, In : Journal of Clinical Psychiatry. 59, SUPPL. 12, p. 35-40 6 p.

Research output: Contribution to journalReview article

Cognition
Antipsychotic Agents
Schizophrenia
Aptitude
Risperidone
48 Citations (Scopus)

Factors affecting outcome in schizophrenia and their relevance for psychopharmacological treatment

Carlo Altamura, A., Bobo, W. V. & Meltzer, H. Y., Sep 1 2007, In : International Clinical Psychopharmacology. 22, 5, p. 249-267 19 p.

Research output: Contribution to journalReview article

Schizophrenia
Psychopathology
Antipsychotic Agents
Mortality
Psychotic Disorders
27 Citations (Scopus)
olanzapine
Dibenzothiazepines
Risperidone
Long-Term Care
Benzodiazepines
201 Citations (Scopus)

Genetic dissection of atypical antipsychotic-induced weight gain: Novel preliminary data on the pharmacogenetic puzzle

Basile, V. S., Masellis, M., McIntyre, R. S., Meltzer, H. Y., Lieberman, J. A. & Kennedy, J. L., Oct 22 2001, In : Journal of Clinical Psychiatry. 62, SUPPL. 23, p. 45-66 22 p.

Research output: Contribution to journalReview article

Pharmacogenetics
Clozapine
Antipsychotic Agents
Weight Gain
Dissection
35 Citations (Scopus)

Long-term effects of neuroleptic drugs on the neuroendocrine system.

Meltzer, H. Y., Jan 1 1985, In : Advances in biochemical psychopharmacology. 40, p. 59-68 10 p.

Research output: Contribution to journalReview article

Physiological Sexual Dysfunctions
Pituitary Diseases
Galactorrhea
Drug Tolerance
Gynecomastia
55 Citations (Scopus)

Lorcaserin and pimavanserin: Emerging selectivity of serotonin receptor subtype-targeted drugs

Meltzer, H. Y. & Roth, B. L., Dec 2 2013, In : Journal of Clinical Investigation. 123, 12, p. 4986-4991 6 p.

Research output: Contribution to journalReview article

Serotonin Receptors
Serotonin
Pharmaceutical Preparations
Physiological Phenomena
Psychotic Disorders
37 Citations (Scopus)

Measuring outcome in schizophrenia: Differences among the atypical antipsychotics

Meltzer, H. Y., Oct 5 1998, In : Journal of Clinical Psychiatry. 59, SUPPL. 12, p. 3-9 7 p.

Research output: Contribution to journalReview article

Antipsychotic Agents
Schizophrenia
olanzapine
Pharmaceutical Economics
Risperidone
20 Citations (Scopus)

Negative symptoms in schizophrenia: a target for new drug development.

Meltzer, H. Y. & Zureick, J., Dec 1 1989, In : Psychopharmacology series. 7, p. 68-77 10 p.

Research output: Contribution to journalReview article

Schizophrenic Psychology
Antipsychotic Agents
Schizophrenia
Pharmaceutical Preparations
90 Citations (Scopus)

Neurocognitive assessment in the clinical antipsychotic trials of intervention effectiveness (CATIE) project schizophrenia trial: Development, methodology, and rationale

Keefe, R. S. E., Mohs, R. C., Bilder, R. M., Harvey, P. D., Green, M. F., Meltzer, H. Y., Gold, J. M. & Sano, M., Jan 1 2003, In : Schizophrenia bulletin. 29, 1, p. 45-55 11 p.

Research output: Contribution to journalReview article

Antipsychotic Agents
Schizophrenia
Clinical Trials
Pharmaceutical Preparations
389 Citations (Scopus)

Neuroleptic withdrawal in schizophrenic patients: A review of the literature

Gilbert, P. L., Harris, M. J., McAdams, L. A., Jeste, D. V., Baldessarini, R. J., Viguera, A. C., Carpenter, W. T., Tamminga, C. A., Greden, J. F., Tandon, R., Meltzer, H. Y., Nuechterlein, K. H., Gitlin, M. J., Subotnik, K. L. & Wyatt, R. J., Jan 1 1995, In : Archives of general psychiatry. 52, 3, p. 173-212 40 p.

Research output: Contribution to journalReview article

Antipsychotic Agents
Recurrence
Schizophrenia
Maintenance
Relapse
53 Citations (Scopus)

Neuromuscular dysfunction in schizophrenia

Meltzer, H. Y., Jan 1 1976, In : Schizophrenia bulletin. 2, 1, p. 106-135 30 p.

Research output: Contribution to journalReview article

Psychotic Disorders
Schizophrenia
Psychiatry
Spinal Cord
Psychotic Affective Disorders
74 Citations (Scopus)

New drugs for the treatment of schizophrenia

Meltzer, H. Y., Jan 1 1993, In : Psychiatric Clinics of North America. 16, 2, p. 365-385 21 p.

Research output: Contribution to journalReview article

Antipsychotic Agents
Schizophrenia
Clozapine
Pharmaceutical Preparations
Remoxipride
11 Citations (Scopus)

New trends in the treatment of schizophrenia

Meltzer, H. Y., Oct 1 2017, In : CNS and Neurological Disorders - Drug Targets. 16, 8, p. 900-906 7 p.

Research output: Contribution to journalReview article

Schizophrenia
Antipsychotic Agents
pamidronate
Pharmacogenetics
Psychotic Disorders
28 Citations (Scopus)

NK3 receptor antagonists for the treatment of schizophrenia

Meltzer, H. & Prus, A., Jun 1 2006, In : Drug Discovery Today: Therapeutic Strategies. 3, 4, p. 555-560 6 p.

Research output: Contribution to journalReview article

Schizophrenia
Limbic System
Aptitude
Cholinergic Agents
Antipsychotic Agents
44 Citations (Scopus)

Pathway-based analysis of GWAS datasets: Effective but caution required

Jia, P., Wang, L., Meltzer, H. Y. & Zhao, Z., May 1 2011, In : International Journal of Neuropsychopharmacology. 14, 4, p. 567-572 6 p.

Research output: Contribution to journalReview article

Genome-Wide Association Study
Psychiatry
Genes
Single Nucleotide Polymorphism
Datasets

Pharmacoeconomic factors related to the treatment of schizophrenia

Meltzer, H., Awad, A. G., Manning W.G., J., Shon, S. P., Diamond, R., Mahmoud, R. & Weisburd, D. E., Mar 10 1999, In : Journal of Clinical Psychiatry. 60, SUPPL. 3, p. 59-60 2 p.

Research output: Contribution to journalReview article

78 Citations (Scopus)

Pharmacogenetics of antipsychotic treatment: Lessons learned from clozapine

Masellis, M., Basile, V. S., Özdemir, V., Meltzer, H. Y., Macciardi, F. M. & Kennedy, J. L., Feb 1 2000, In : Biological psychiatry. 47, 3, p. 252-266 15 p.

Research output: Contribution to journalReview article

Clozapine
Pharmacogenetics
Antipsychotic Agents
Therapeutics
Schizophrenia
15 Citations (Scopus)

Pharmacotherapy of cognition in schizophrenia

Meltzer, H. Y., Aug 1 2015, In : Current Opinion in Behavioral Sciences. 4, p. 115-121 7 p.

Research output: Contribution to journalReview article

Cognition
Antipsychotic Agents
Schizophrenia
pamidronate
Drug Therapy
28 Citations (Scopus)

Platelet MAO activity in hallucinating and paranoid schizophrenics: A review and meta-analysis

Zureick, J. L. & Meltzer, H. Y., Jan 1 1988, In : Biological psychiatry. 24, 1, p. 63-78 16 p.

Research output: Contribution to journalReview article

Monoamine Oxidase
Meta-Analysis
Blood Platelets
Antipsychotic Agents
Reference Values
687 Citations (Scopus)

Practice guideline for the treatment of patients with schizophrenia

Herz, M. I., Liberman, R. P., McGlashan, T. H., Lieberman, J. A., Wyatt, R. J., Marder, S. R., Wang, P., Allgulander, C., Baldessarini, R. J., Balon, R., Bellack, A. S., Berlin, J., Blackington, C. H., Buckley, P., Carlson, D. G., Cott, J., Cournos, F., Desai, P., Dickstein, L., Fenton, W. S. & 78 others, Fisher, W. A., Flaherty, L. T., Freedman, R., Galanter, M., Galton, E., Ganguli, R., Garrettson, L. K., Goldfinger, S., Goldman, L. S., Goldstein, M. Z., Gordy, T. R., Gray, S. H., Green, M. R., Greenberg, W. M., Gunderson, J. G., Hall, L. L., Haller, E., Hanin, E., Hawkins, L., Hester, T. W., Horn, T., Hsiao, J. K., Juthani, N. V., Kane, J. M., Kayser, A., Kibel, H. D., Kimmich, R. A., Koegler, R. R., Krajeski, J., Kuehnel, T., Lamberti, J. S., Lehman, A., Leunello, J., Martin, R. L., McCarley, R., McGee, M., Meltzer, H. Y., Mesulam, M., Metzner, J. L., Mosher, L. R., Motto, J. A., Mueser, K. T., Munoz, R. A., Nasrallah, H. A., Newcomer, J. W., Opler, L. A., Peterson, G. N., Rapaport, M., Riba, M., Rickert, V. I., Rifkin, A., Rivenbark, J. S., Robertson, S., Ruiz, P., Ryan, W. G., Sanderson, M. O., Schiffer, R. B., Schyve, P. M., Sebring, R. H., Shen, W. W., Shore, D., Simpson, G. M., Soufi, H. E., Stein, L. I., Stotland, N., Strauss, J., Sundberg, D., Svendsen, D., Tohen, M., Tsuang, M., Wagnitz, J. G., Weiner, R., Weitzel, W. D., Wilkerson, L. J., Wingerson, D., Zarate, J., Zito, J. & Zonana, H. V., Jan 1 1997, In : American Journal of Psychiatry. 154, 4 SUPPL., p. 1-63 63 p.

Research output: Contribution to journalReview article

Pre-clinical pharmacology of atypical antipsychotic drugs: a selective review.

Meltzer, H. Y., May 1 1996, In : The British journal of psychiatry. Supplement. 29, p. 23-31 9 p.

Research output: Contribution to journalReview article

Preclinical Drug Evaluations
Clinical Pharmacology
Serotonin Receptors
Synaptic Transmission
Antipsychotic Agents
68 Citations (Scopus)

Pre-clinical pharmacology of atypical antipsychotic drugs: A selective review

Meltzer, H. Y., Jan 1 1996, In : British Journal of Psychiatry. 168, MAY SUPPL. 29, p. 23-31 9 p.

Research output: Contribution to journalReview article

Clinical Pharmacology
Antipsychotic Agents
36 Citations (Scopus)

Psychological and behavioural effects of interferons

Bonaccorso, S., Meltzer, H. & Maes, M., Nov 25 2000, In : Current opinion in psychiatry. 13, 6, p. 673-677 5 p.

Research output: Contribution to journalReview article

Interferons
Immunotherapy
Psychology
Depression
Tryptophan
17 Citations (Scopus)

Psychosis of Parkinson's disease: Serotonin 2A receptor inverse agonists as potential therapeutics

Weiner, D. M., Vanover, K. E., Brann, M. R., Meltzer, H. Y. & Davis, R. E., Jul 1 2003, In : Current Opinion in Investigational Drugs. 4, 7, p. 815-819 5 p.

Research output: Contribution to journalReview article

Receptor, Serotonin, 5-HT2A
Psychotic Disorders
Parkinson Disease
Therapeutics
Movement Disorders