Hiam Abdala-Valencia

  • 862 Citations
19992022
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Personal profile

Research Interests

Application of next generation sequencing technology and integrative “wet” lab approaches to basic and translational research of lung diseases, including but not limited to: asthma, COPD, pulmonary fibrosis, acute lung injury. Understanding systemic influences on lung biology in health and disease, such as impact of central metabolism and epigenetic control of developmental checkpoints

Education/Academic qualification

PhD, University of Nantes, France

… → 2001

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Grants 2012 2022

Research Output 1999 2018

  • 862 Citations
  • 41 Article
  • 3 Review article
  • 2 Comment/debate
3 Citations

DNA methylation regulates the neonatal CD4 T-cell response to pneumonia in mice

McGrath-Morrow, S. A., Ndeh, R., Helmin, K. A., Chen, S. Y., Anekalla, K. R., Abdala-Valencia, H., D’Alessio, F. R., Michael Collaco, J. & Singer, B., Jan 1 2018, In : Journal of Biological Chemistry. 293, 30, p. 11772-11783 12 p.

Research output: Contribution to journalArticle

T-cells
DNA Methylation
Pneumonia
T-Lymphocytes
Pediatrics

Inflammatory pathways are upregulated in the nasal epithelium in patients with idiopathic pulmonary fibrosis

Sala, M. A., Balderas-Martínez, Y. I., Buendía-Roldan, I., Abdala-Valencia, H., Nam, K., Jain, M., Bhorade, S. M., Bharat, A., Reyfman, P. A., Ridge, K. M., Pardo, A., Sznajder, J. I., Budinger, GR. S., Misharin, A. & Selman, M., Nov 26 2018, In : Respiratory Research. 19, 1, 233.

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
Nasal Mucosa
Nose
Up-Regulation
RNA Sequence Analysis

Matrix protein tenascin-C expands and reversibly blocks maturation of murine eosinophil progenitors

Doan, T. C., Jeong, B. M., Coden, M. E., Loffredo, L. F., Bhattacharyya, S., Chiarella, S. E., Varga, J., Abdala-Valencia, H. & Berdnikovs, S., Aug 1 2018, In : Journal of Allergy and Clinical Immunology. 142, 2, p. 695-698.e4

Research output: Contribution to journalArticle

Tenascin
Protein C
Eosinophils

Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis

Soberanes, S., Misharin, A. V., Jairaman, A., Morales-Nebreda, L., McQuattie-Pimentel, A. C., Cho, T., Hamanaka, R. B., Meliton, A. Y., Reyfman, P. A., Walter, J. M., Chen, C-I., Chi, M., Chiu, S., Gonzalez-Gonzalez, F. J., Antalek, M., Abdala-Valencia, H., Chiarella, S. E., Sun, K. A., Woods, P. S., Ghio, A. J. & 12 othersJain, M., Perlman, H., Ridge, K. M., Morimoto, R. I., Sznajder, J. I., Balch, W. E., Bhorade, S. M., Bharat, A., Prakriya, M., Chandel, N. S., Mutlu, G. M. & Budinger, G. R. S., Oct 11 2018, In : Cell Metabolism.

Research output: Contribution to journalArticle

Metformin
Air Pollution
Electron Transport
Particulate Matter
Alveolar Macrophages

Multidimensional assessment of alveolar T cells in critically ill patients

Walter, J. M., Helmin, K. A., Abdala-Valencia, H., Wunderink, R. G. & Singer, B. D., Sep 6 2018, In : JCI Insight. 3, 17

Research output: Contribution to journalArticle

Alveolar Epithelial Cells
Critical Illness
Pneumonia
T-Lymphocytes
RNA Sequence Analysis