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Hiam Abdala-Valencia

  • 964 Citations
19992022
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Personal profile

Research Interests

Application of next generation sequencing technology and integrative “wet” lab approaches to basic and translational research of lung diseases, including but not limited to: asthma, COPD, pulmonary fibrosis, acute lung injury. Understanding systemic influences on lung biology in health and disease, such as impact of central metabolism and epigenetic control of developmental checkpoints

Education/Academic qualification

PhD, University of Nantes, France

… → 2001

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Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2012 2022

Successful Clinical Response In Pneumonia Therapy (SCRIPT) Systems Biology Center

Abdala-Valencia, H., Amaral, L. A. N., Bartom, E. T., Budinger, G. S., Davuluri, R. V., Hauser, A. R., Horvath, C. M., Kandpal, M., Misharin, A., Ozer, E. A., Qi, C., Singer, B., Starren, J. B., Wehbe, F., Winter, D. R. & Wunderink, R. G.

National Institute of Allergy and Infectious Diseases

1/17/18 → 12/31/22

Project: Research project

Systems Biology
Pneumonia
Microbiota
Biomarkers
Fungal DNA

VCAM-1 Signals in Endothelial Cells during Leukocyte Transendothelial Migration

Abdala-Valencia, H. & Cook-Mills, J. M.

American Heart Association Midwest Affiliate

7/1/12 → 6/30/14

Project: Research project

Research Output 1999 2019

  • 964 Citations
  • 45 Article
  • 3 Comment/debate
  • 3 Review article
  • 1 Letter

Erratum: Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis (Cell Metabolism (2019) 29(2) (335–347.e5), (S1550413118305862) (10.1016/j.cmet.2018.09.019))

Soberanes, S., Misharin, A., Jairaman, A., Morales-Nebreda, L., McQuattie-Pimentel, A. C., Cho, T., Hamanaka, R. B., Meliton, A. Y., Reyfman, P. A., Walter, J. M., Chen, C. I., Chi, M., Chiu, S., Gonzalez-Gonzalez, F. J., Antalek, M., Abdala-Valencia, H., Chiarella, S. E., Sun, K. A., Woods, P. S., Ghio, A. J. & 12 othersJain, M., Perlman, H. R., Ridge, K. M., Morimoto, R. I., Sznajder, J. I., Balch, W. E., Bhorade, S. M., Bharat, A., Prakriya, M., Chandel, N., Mutlu, G. M. & Budinger, GR. S., Feb 5 2019, In : Cell Metabolism. 29, 2, 1 p.

Research output: Contribution to journal › Comment/debate

Metformin
Air Pollution
Electron Transport
Names
Publications
6 Citations (Scopus)

Mitochondrial complex III is essential for suppressive function of regulatory T cells

Weinberg, S. E., Singer, B., Steinert, E. M., Martinez, C. A., Mehta, M. M., Martínez-Reyes, I., Gao, P., Helmin, K. A., Abdala-Valencia, H., Sena, L. A., Schumacker, P. T., Turka, L. A. & Chandel, N., Jan 24 2019, In : Nature. 565, 7740, p. 495-499 5 p.

Research output: Contribution to journal › Letter

Electron Transport Complex III
Regulatory T-Lymphocytes
Electron Transport
T-Lymphocytes
Self Tolerance
1 Citation (Scopus)

Multidimensional assessment of the host response in mechanically ventilated patients with suspected pneumonia

Walter, J. M., Ren, Z., Yacoub, T., Reyfman, P. A., Shah, R. D., Abdala-Valencia, H., Nam, K., Morgan, V. K., Anekalla, K. R., Joshi, N., McQuattie-Pimentel, A. C., Chen, C. I., Chi, M., Han, S. H., Gonzalez-Gonzalez, F. J., Soberanes, S., Aillon, R. P., Watanabe, S., Williams, K. J. N., Lu, Z. & 13 othersPaonessa, J., Hountras, P., Breganio, M., Borkowski, N., Donnelly, H. K., Allen, J. P., Amaral, L. A. N., Bharat, A., Misharin, A. V., Bagheri, N., Hauser, A. R., Budinger, GR. S. & Wunderink, R. G., May 15 2019, In : American journal of respiratory and critical care medicine. 199, 10, p. 1225-1237 13 p.

Research output: Contribution to journal › Article

Bacterial Pneumonia
Pneumonia
Macrophages
Bronchoalveolar Lavage Fluid
Alveolar Macrophages
7 Citations (Scopus)

Single-cell transcriptomic analysis of human lung provides insights into the pathobiology of pulmonary fibrosis

Reyfman, P. A., Walter, J. M., Joshi, N., Anekalla, K. R., McQuattie-Pimentel, A. C., Chiu, S., Fernandez, R., Akbarpour, M., Chen, C. I., Ren, Z., Verma, R., Abdala-Valencia, H., Nam, K., Chi, M., Han, S. H., Gonzalez-Gonzalez, F. J., Soberanes, S., Watanabe, S., Williams, K. J. N., Flozak, A. S. & 29 othersNicholson, T. T., Morgan, V. K., Winter, D. R., Hinchcliff, M., Hrusch, C. L., Guzy, R. D., Bonham, C. A., Sperling, A. I., Bag, R., Hamanaka, R. B., Mutlu, G. M., Yeldandi, A. V., Marshall, S. A., Shilatifard, A., Amaral, L. A. N., Perlman, H., Sznajder, J. I., Christine Argento, A., Gillespie, C. T., Dematte, J., Jain, M., Singer, B. D., Ridge, K. M., Lam, A. P., Bharat, A., Bhorade, S. M., Gottardi, C., Budinger, GR. S. & Misharin, A. V., Jun 15 2019, In : American journal of respiratory and critical care medicine. 199, 12, p. 1517-1536 20 p.

Research output: Contribution to journal › Article

Open Access
Single-Cell Analysis
Pulmonary Fibrosis
Lung
RNA Sequence Analysis
Alveolar Macrophages

Transcriptional consequences of impaired immune cell responses induced by cystic fibrosis plasma characterized via dual RNA sequencing

Ideozu, J. E., Rangaraj, V., Abdala-Valencia, H., Zhang, X., Kandpal, M., Sala, M. A., Davuluri, R. V. & Levy, H., Jan 1 2019, In : BMC Medical Genomics. 12, 1, 66.

Research output: Contribution to journal › Article

Open Access
RNA Sequence Analysis
Cystic Fibrosis
MicroRNAs
Phenotype
Blood Cells