Hiam Abdala-Valencia

  • 964 Citations
19992022
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Personal profile

Research Interests

Application of next generation sequencing technology and integrative “wet” lab approaches to basic and translational research of lung diseases, including but not limited to: asthma, COPD, pulmonary fibrosis, acute lung injury. Understanding systemic influences on lung biology in health and disease, such as impact of central metabolism and epigenetic control of developmental checkpoints

Education/Academic qualification

PhD, University of Nantes, France

… → 2001

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Grants 2012 2022

Research Output 1999 2019

  • 964 Citations
  • 45 Article
  • 3 Comment/debate
  • 3 Review article
  • 1 Letter

Erratum: Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis (Cell Metabolism (2019) 29(2) (335–347.e5), (S1550413118305862) (10.1016/j.cmet.2018.09.019))

Soberanes, S., Misharin, A., Jairaman, A., Morales-Nebreda, L., McQuattie-Pimentel, A. C., Cho, T., Hamanaka, R. B., Meliton, A. Y., Reyfman, P. A., Walter, J. M., Chen, C. I., Chi, M., Chiu, S., Gonzalez-Gonzalez, F. J., Antalek, M., Abdala-Valencia, H., Chiarella, S. E., Sun, K. A., Woods, P. S., Ghio, A. J. & 12 othersJain, M., Perlman, H. R., Ridge, K. M., Morimoto, R. I., Sznajder, J. I., Balch, W. E., Bhorade, S. M., Bharat, A., Prakriya, M., Chandel, N., Mutlu, G. M. & Budinger, GR. S., Feb 5 2019, In : Cell Metabolism. 29, 2, 1 p.

Research output: Contribution to journalComment/debate

Metformin
Air Pollution
Electron Transport
Names
Publications
6 Citations (Scopus)

Mitochondrial complex III is essential for suppressive function of regulatory T cells

Weinberg, S. E., Singer, B., Steinert, E. M., Martinez, C. A., Mehta, M. M., Martínez-Reyes, I., Gao, P., Helmin, K. A., Abdala-Valencia, H., Sena, L. A., Schumacker, P. T., Turka, L. A. & Chandel, N., Jan 24 2019, In : Nature. 565, 7740, p. 495-499 5 p.

Research output: Contribution to journalLetter

Electron Transport Complex III
Regulatory T-Lymphocytes
Electron Transport
T-Lymphocytes
Self Tolerance
1 Citation (Scopus)

Multidimensional assessment of the host response in mechanically ventilated patients with suspected pneumonia

Walter, J. M., Ren, Z., Yacoub, T., Reyfman, P. A., Shah, R. D., Abdala-Valencia, H., Nam, K., Morgan, V. K., Anekalla, K. R., Joshi, N., McQuattie-Pimentel, A. C., Chen, C. I., Chi, M., Han, S. H., Gonzalez-Gonzalez, F. J., Soberanes, S., Aillon, R. P., Watanabe, S., Williams, K. J. N., Lu, Z. & 13 othersPaonessa, J., Hountras, P., Breganio, M., Borkowski, N., Donnelly, H. K., Allen, J. P., Amaral, L. A. N., Bharat, A., Misharin, A. V., Bagheri, N., Hauser, A. R., Budinger, GR. S. & Wunderink, R. G., May 15 2019, In : American journal of respiratory and critical care medicine. 199, 10, p. 1225-1237 13 p.

Research output: Contribution to journalArticle

Bacterial Pneumonia
Pneumonia
Macrophages
Bronchoalveolar Lavage Fluid
Alveolar Macrophages
7 Citations (Scopus)

Single-cell transcriptomic analysis of human lung provides insights into the pathobiology of pulmonary fibrosis

Reyfman, P. A., Walter, J. M., Joshi, N., Anekalla, K. R., McQuattie-Pimentel, A. C., Chiu, S., Fernandez, R., Akbarpour, M., Chen, C. I., Ren, Z., Verma, R., Abdala-Valencia, H., Nam, K., Chi, M., Han, S. H., Gonzalez-Gonzalez, F. J., Soberanes, S., Watanabe, S., Williams, K. J. N., Flozak, A. S. & 29 othersNicholson, T. T., Morgan, V. K., Winter, D. R., Hinchcliff, M., Hrusch, C. L., Guzy, R. D., Bonham, C. A., Sperling, A. I., Bag, R., Hamanaka, R. B., Mutlu, G. M., Yeldandi, A. V., Marshall, S. A., Shilatifard, A., Amaral, L. A. N., Perlman, H., Sznajder, J. I., Christine Argento, A., Gillespie, C. T., Dematte, J., Jain, M., Singer, B. D., Ridge, K. M., Lam, A. P., Bharat, A., Bhorade, S. M., Gottardi, C., Budinger, GR. S. & Misharin, A. V., Jun 15 2019, In : American journal of respiratory and critical care medicine. 199, 12, p. 1517-1536 20 p.

Research output: Contribution to journalArticle

Open Access
Single-Cell Analysis
Pulmonary Fibrosis
Lung
RNA Sequence Analysis
Alveolar Macrophages
Open Access
RNA Sequence Analysis
Cystic Fibrosis
MicroRNAs
Phenotype
Blood Cells