Research Output per year
Research Output per year
Personal profile
Research Interests
Dr. Hirai's research interest focus on Lung and vascular progenitor cells/stem cells and the molecular mechanisms of Lung and vascular disease.
Dr. Hirai joined Northwestern University in July 2018 from University of Michigan, Ann Arbor. Dr. Hirai completed his postdoctoral training in Molecular pharmacology and Stem cell biology at Northwestern University, Chicago and University of Minnesota, Twin Cities.
Education/Academic qualification
PhD, Tokyo Medical and Dental University
… → 2003
Research interests
- Biotechnology
- Cardiovascular Diseases
- Cell Biology
- Lung Injury
- Stem Cells
- Vascular Biology
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Research Output
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Efficient Gene Editing at Major CFTR Mutation Loci
Ruan, J., Hirai, H., Yang, D., Ma, L., Hou, X., Jiang, H., Wei, H., Rajagopalan, C., Mou, H., Wang, G., Zhang, J., Li, K., Chen, Y. E., Sun, F. & Xu, J., Jun 7 2019, In: Molecular Therapy - Nucleic Acids. 16, p. 73-81 9 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
Generation of induced pluripotent stem cells from Chinese hamster embryonic fibroblasts
Pei, H., Fu, H. Y., Cho, D. S., Hu, W. S., Pei, H., Cho, D. S., O'Brien, T. D., Dutton, J., Hu, W. S., Pei, H., Hirai, H., Verfaillie, C. M. & O'Brien, T. D., May 1 2017, In: Stem Cell Research. 21, p. 132-136 5 p.Research output: Contribution to journal › Article › peer-review
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Yes-Associated Protein Inhibits Transcription of Myocardin and Attenuates Differentiation of Vascular Smooth Muscle Cell from Cardiovascular Progenitor Cell Lineage
wang, L., Qiu, P., Jiao, J., Hirai, H., Xiong, W., Zhang, J., Zhu, T., Ma, P. X., Chen, Y. E. & Yang, B., Feb 1 2017, In: Stem Cells. 35, 2, p. 351-361 11 p.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Differentiation defect in neural crest-derived smooth muscle cells in patients with aortopathy associated with bicuspid aortic valves
Jiao, J., Xiong, W., Wang, L., Yang, J., Qiu, P., Hirai, H., Shao, L., Milewicz, D., Chen, Y. E. & Yang, B., Aug 2016, In: EBioMedicine. 10, p. 282-290 9 p.Research output: Contribution to journal › Article › peer-review
35 Scopus citations -
Genome-wide identification and analysis of mRNA expression in fibroblasts, ES cells, and iPS cells
Hirai, H. & Kikyo, N., Mar 1 2016, In: Genomics Data. 7, p. 171-172 2 p.Research output: Contribution to journal › Article › peer-review