Research Output per year
Research Output per year
Personal profile
Research Interests
Dr. Hirai's research interest focus on Lung and vascular progenitor cells/stem cells and the molecular mechanisms of Lung and vascular disease.
Dr. Hirai joined Northwestern University in July 2018 from University of Michigan, Ann Arbor. Dr. Hirai completed his postdoctoral training in Molecular pharmacology and Stem cell biology at Northwestern University, Chicago and University of Minnesota, Twin Cities.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Tokyo Medical and Dental University
… → 2003
Research interests
- Biotechnology
- Cardiovascular Diseases
- Cell Biology
- Lung Injury
- Stem Cells
- Vascular Biology
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The sodium/glucose cotransporters as potential therapeutic targets for CF lung diseases revealed by human lung organoid swelling assay
Hirai, H., Liang, X., Sun, Y., Zhang, Y., Zhang, J., Chen, Y. E., Mou, H., Zhao, Y. & Xu, J., Mar 10 2022, In: Molecular Therapy - Methods and Clinical Development. 24, p. 11-19 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Efficient Gene Editing at Major CFTR Mutation Loci
Ruan, J., Hirai, H., Yang, D., Ma, L., Hou, X., Jiang, H., Wei, H., Rajagopalan, C., Mou, H., Wang, G., Zhang, J., Li, K., Chen, Y. E., Sun, F. & Xu, J., Jun 7 2019, In: Molecular Therapy - Nucleic Acids. 16, p. 73-81 9 p.Research output: Contribution to journal › Article › peer-review
Open Access44 Scopus citations -
Direct reprogramming of fibroblasts into smooth muscle-like cells with defined transcription factors-brief report
Hirai, H., Yang, B., Garcia-Barrio, M. T., Rom, O., Ma, P. X., Zhang, J. & Chen, Y. E., 2018, In: Arteriosclerosis, thrombosis, and vascular biology. 38, 9, p. 2191-2197 7 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Generation of induced pluripotent stem cells from Chinese hamster embryonic fibroblasts
Pei, H., Fu, H. Y., Cho, D. S., Hu, W. S., Pei, H., Cho, D. S., O'Brien, T. D., Dutton, J., Hu, W. S., Pei, H., Hirai, H., Verfaillie, C. M. & O'Brien, T. D., May 1 2017, In: Stem Cell Research. 21, p. 132-136 5 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Yes-Associated Protein Inhibits Transcription of Myocardin and Attenuates Differentiation of Vascular Smooth Muscle Cell from Cardiovascular Progenitor Cell Lineage
wang, L., Qiu, P., Jiao, J., Hirai, H., Xiong, W., Zhang, J., Zhu, T., Ma, P. X., Chen, Y. E. & Yang, B., Feb 1 2017, In: Stem Cells. 35, 2, p. 351-361 11 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations