Hiroyuki Hirai

  • 766 Citations

Research output per year

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Personal profile

Research Interests

Dr. Hirai's research interest focus on Lung and vascular progenitor cells/stem cells and the molecular mechanisms of Lung and vascular disease.

Dr. Hirai joined Northwestern University in July 2018 from University of Michigan, Ann Arbor. Dr. Hirai completed his postdoctoral training in Molecular pharmacology and Stem cell biology at Northwestern University, Chicago and University of Minnesota, Twin Cities.

Education/Academic qualification

PhD, Tokyo Medical and Dental University

… → 2003

Research interests

  • Biotechnology
  • Cardiovascular Diseases
  • Cell Biology
  • Lung Injury
  • Stem Cells
  • Vascular Biology

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Research Output

  • 766 Citations
  • 23 Article
  • 2 Review article
  • 1 Letter

Efficient Gene Editing at Major CFTR Mutation Loci

Ruan, J., Hirai, H., Yang, D., Ma, L., Hou, X., Jiang, H., Wei, H., Rajagopalan, C., Mou, H., Wang, G., Zhang, J., Li, K., Chen, Y. E., Sun, F. & Xu, J., Jun 7 2019, In : Molecular Therapy - Nucleic Acids. 16, p. 73-81 9 p.

Research output: Contribution to journalArticle

Open Access
  • 13 Scopus citations

    Direct reprogramming of fibroblasts into smooth muscle-like cells with defined transcription factors-brief report

    Hirai, H., Yang, B., Garcia-Barrio, M. T., Rom, O., Ma, P. X., Zhang, J. & Chen, Y. E., Jan 1 2018, In : Arteriosclerosis, thrombosis, and vascular biology. 38, 9, p. 2191-2197 7 p.

    Research output: Contribution to journalArticle

  • 6 Scopus citations

    Generation of induced pluripotent stem cells from Chinese hamster embryonic fibroblasts

    Pei, H., Fu, H. Y., Cho, D. S., Hu, W. S., Pei, H., Cho, D. S., O'Brien, T. D., Dutton, J., Hu, W. S., Pei, H., Hirai, H., Verfaillie, C. M. & O'Brien, T. D., May 1 2017, In : Stem Cell Research. 21, p. 132-136 5 p.

    Research output: Contribution to journalArticle

  • Yes-Associated Protein Inhibits Transcription of Myocardin and Attenuates Differentiation of Vascular Smooth Muscle Cell from Cardiovascular Progenitor Cell Lineage

    wang, L., Qiu, P., Jiao, J., Hirai, H., Xiong, W., Zhang, J., Zhu, T., Ma, P. X., Chen, Y. E. & Yang, B., Feb 1 2017, In : Stem Cells. 35, 2, p. 351-361 11 p.

    Research output: Contribution to journalArticle

  • 9 Scopus citations

    Differentiation defect in neural crest-derived smooth muscle cells in patients with aortopathy associated with bicuspid aortic valves

    Jiao, J., Xiong, W., Wang, L., Yang, J., Qiu, P., Hirai, H., Shao, L., Milewicz, D., Chen, Y. E. & Yang, B., Aug 2016, In : EBioMedicine. 10, p. 282-290 9 p.

    Research output: Contribution to journalArticle

  • 29 Scopus citations