Grants per year
Personal profile
Research Interests
Dr. Dong’s laboratory has focused on a continuous and integrated program of investigating genetic alterations and environmental effects on neurodevelopment and aging, and their relevance to the pathogenesis of neurodegenerative and neuropsychiatric disorders, particularly Alzheimer’s disease. Ongoing NIH funded projects to discover novel molecular genetics and epigenetic mechanisms underlying neuropsychological disorders, using human antemortem clinical assessments and postmortem tissues, as well as animal models. The findings from the translational work will help in the development of new therapeutic strategies to slow disease onset and prevent progression.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Neurobiology, West China University
… → 1992
MD, Medicine, Zhunyi Medical College
… → 1983
Research interests keywords
- Aging
- Alzheimer's Disease
- Cognitive Neuroscience
- Dementia
- Neurobiology
- Neurogenetics
- Neuroscience
- Psychiatry
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Estrogen, Astrocyte Reactivity, and Sex Differences in Alzheimer's Disease
Bulun, S. E., Dong, H., Zhao, H. & Mesulam, M.
4/1/23 → 3/31/26
Project: Research project
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Epigenetic Regulation in Aging and Alzheimer's Disease
Dong, H., Carvill, G. L., Csernansky, J. G. & Geula, C.
12/15/22 → 11/30/27
Project: Research project
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Predoctoral and Postdoctoral Training Program in Aging and Dementia
Vassar, R. J., Weintraub, S., Allada, R., Bevan, M. D., Caraveo Piso, G., Carvill, G. L., Chan, S., Contractor, A., Disterhoft, J. F., Dombeck, D. A., Dong, H., Ferreira, A. B., Flanagan, M. E., Gefen, T. D., Geula, C., Gratton, C., He, C., Kahnt, T., Kalb, R. G., Kennedy, A., Kessler, J., Kiskinis, E., Klein, W. L., Kozorovitskiy, Y., Krainc, D., Li, L., Mazzulli, J., Mesulam, M., Miller, R. J., Morimoto, R. I., Opal, P., Ozdinler, H., Paller, K., Parisiadou, L., Penzes, P., Pinto, L., Prakriya, M., Reber, P. J., Roberts, A. L., Rogalski, E., Savas, J. N., Surmeier Jr, D. J., Swanson, G. T., Voss, J. L., Zee, P. C. & Zelano, C.
5/1/22 → 4/30/27
Project: Research project
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Concordance of TDP-43 Inclusions with Cortical Atrophy and Clinical Phenotype
Geula, C., Bigio, E. H., Dong, H., Mesulam, M., Vassar, R. J. & Zhang, H.
National Institute of Neurological Disorders and Stroke
4/1/20 → 3/31/25
Project: Research project
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Characterization of apathy-like behaviors in the 5xFAD mouse model of Alzheimer's disease
Keszycki, R., Rodriguez, G., Dunn, J. T., Locci, A., Orellana, H., Haupfear, I., Dominguez, S., Fisher, D. W. & Dong, H., Jun 2023, In: Neurobiology of Aging. 126, p. 113-122 10 p.Research output: Contribution to journal › Article › peer-review
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Histone deacetylase 1 regulates haloperidol-induced motor side effects in aged mice
McClarty, B. M., Chakraborty, S., Rodriguez, G. & Dong, H., Jun 5 2023, In: Behavioural Brain Research. 447, 114420.Research output: Contribution to journal › Article › peer-review
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Histone deacetylase inhibitors mitigate antipsychotic risperidone-induced motor side effects in aged mice and in a mouse model of Alzheimer’s disease
Rodriguez, G., Fisher, D. W., McClarty, B., Montalvo-Ortiz, J., Cui, Q., Chan, C. S. & Dong, H., Jan 6 2023, In: Frontiers in Psychiatry. 13, 1020831.Research output: Contribution to journal › Article › peer-review
Open Access -
Multisite chronic pain: a risk factor for dementia
Dong, H., Jun 2023, In: Nature Reviews Neurology. 19, 6, p. 331-332 2 p.Research output: Contribution to journal › Comment/debate › peer-review
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Population-attributable fractions of risk factors for all-cause dementia in China rural and urban areas: a cross-sectional study
Hu, F. F., Cheng, G. R., Liu, D., Liu, Q., Gan, X. G., Li, L., Wang, X. D., Zhang, B., An, L. N., Chen, C., Zou, M. J., Xu, L., Ou, Y. M., Chen, Y. S., Li, J. Q., Wei, Z., Wang, Y. Y., Wu, Q., Chen, X. X., Yang, X. F., & 18 others, Jun 2022, In: Journal of Neurology. 269, 6, p. 3147-3158 12 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations
Datasets
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Brain aromatase and the regulation of sexual activity in male mice
Brooks, D. C. (Contributor), Coon, J. S. V. (Contributor), Ercan, C. M. (Contributor), Xu, X. (Contributor), Dong, H. (Contributor), Levine, J. E. (Contributor), Bulun, S. E. (Contributor), Zhao, H. (Contributor), Coon V, J. S. (Contributor) & Levine, J. E. (Contributor), ZENODO, Sep 18 2020
DOI: 10.5061/dryad.5mkkwh72t, https://zenodo.org/record/4069415
Dataset
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Brain aromatase and the regulation of sexual activity in male mice
Brooks, D. C. (Creator), Coon, J. S. V. (Contributor), Ercan, C. M. (Creator), Xu, X. (Creator), Dong, H. (Creator), Levine, J. E. (Creator), Bulun, S. E. (Creator), Zhao, H. (Creator), Coon V, J. S. (Creator), Dong, H. (Creator), Levine, J. E. (Creator) & Zhao, H. (Creator), Dryad, 2020
DOI: 10.5061/dryad.5mkkwh72t, https://datadryad.org/stash/dataset/doi:10.5061/dryad.5mkkwh72t
Dataset