If you made any changes in Pure, your changes will be visible here soon.

Personal profile

Research Interests

Dr. Dong’s laboratory has focused on a continuous and integrated program of investigating genetic alterations and environmental effects on neurodevelopment and aging, and their relevance to the pathogenesis of neurodegenerative and neuropsychiatric disorders, particularly Alzheimer’s disease. Ongoing NIH funded projects to discover novel molecular genetics and epigenetic mechanisms underlying neuropsychological disorders, using human antemortem clinical assessments and postmortem tissues, as well as animal models. The findings from the translational work will help in the development of new therapeutic strategies to slow disease onset and prevent progression.

Education/Academic qualification

PhD, West China University

… → 1992

MD, Zhunyi Medical College

… → 1983

Research interests

  • Aging
  • Alzheimer's Disease
  • Cognitive Neuroscience
  • Dementia
  • Neurobiology
  • Neurogenetics
  • Neuroscience
  • Psychiatry

Fingerprint Dive into the research topics where Hongxin Dong is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 15 Similar Profiles
Alzheimer Disease Medicine & Life Sciences
Hippocampus Medicine & Life Sciences
Spinal Cord Medicine & Life Sciences
Kainic Acid Medicine & Life Sciences
Corticotropin-Releasing Hormone Medicine & Life Sciences
Dementia Medicine & Life Sciences
Amyloid Medicine & Life Sciences
Brain Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2006 2023

Behavioral Symptoms
Alzheimer Disease
Endoplasmic Reticulum-Associated Degradation
Sex Characteristics
Alzheimer Disease
Corticotropin-Releasing Hormone
Transgenic Mice
Sex Characteristics
Alzheimer Disease
Corticotropin-Releasing Hormone
Transgenic Mice
Histone Code
Antipsychotic Agents
Histone Deacetylase Inhibitors
Drug-Related Side Effects and Adverse Reactions

Research Output 1998 2019

  • 2308 Citations
  • 47 Article
  • 10 Review article
  • 2 Comment/debate
  • 1 Editorial

Editorial: Stress and its impact on Alzheimer's Disease

Dong, H. & Csernansky, J. G., Feb 1 2019, In : Neurobiology of Stress. 10, 100167.

Research output: Contribution to journalEditorial

Open Access
Alzheimer Disease
2 Citations (Scopus)

Serotonergic system, cognition, and BPSD in Alzheimer's disease

Chakraborty, S., Lennon, J. C., Malkaram, S. A., Zeng, Y., Fisher, D. W. & Dong, H., Jun 21 2019, In : Neuroscience Letters. 704, p. 36-44 9 p.

Research output: Contribution to journalReview article

Behavioral Symptoms
Alzheimer Disease

The hyperactivity-impulsivity-irritiability-disinhibition-aggression-agitation domain in Alzheimer's disease: Current management and future directions

Keszycki, R. M., Fisher, D. W. & Dong, H., Jan 1 2019, In : Frontiers in Pharmacology. 10, SEP, 1109.

Research output: Contribution to journalReview article

Open Access
Impulsive Behavior
Disease Management
Alzheimer Disease
Behavioral Symptoms

The link between chronic pain and Alzheimer's disease

Cao, S., Fisher, D. W., Yu, T. & Dong, H., Nov 6 2019, In : Journal of neuroinflammation. 16, 1, 204.

Research output: Contribution to journalReview article

Open Access
Chronic Pain
Alzheimer Disease
Chronic Disease
Locus Coeruleus
Neurodegenerative Diseases
10 Citations (Scopus)

Axonal organization defects in the hippocampus of adult conditional BACE1 knockout mice

Ou-Yang, M. H., Kurz, J. E., Nomura, T., Popovic, J., Rajapaksha, T. W., Dong, H., Contractor, A., Chetkovich, D. M., Tourtellotte, W. G. & Vassar, R., Sep 19 2018, In : Science translational medicine. 10, 459, eaao5620.

Research output: Contribution to journalArticle

Knockout Mice
Alzheimer Disease