Grants per year
Personal profile
Research Interests
Research interests: role of mitochondria and metabolism in cardiovascular disease; cellular iron regulation. Clinical interests: general and preventive cardiology.
Certifications and Licenses
Cardiovascular Disease |
Training Experience
2001 | Residency, Johns Hopkins Hospital |
2004 | Fellowship, Johns Hopkins Hospital |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Medicine, MD, Vanderbilt University
… → 1998
Molecular Physiology, PhD, Vanderbilt University
… → 1996
Research interests keywords
- Cardiology
- Cardiovascular Diseases
- Heart Disease
- Intracellular Transport
- Metabolism
- Molecular Biology
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Collaborations and top research areas from the last five years
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Medical Scientist Training Program
Ardehali, H. (PD/PI), Hauser, A. R. (PD/PI), Hauser, A. R. (PD/PI), Brown, M. A. (Other), Brown, M. A. (Other), Kalb, R. G. (Other) & Kalb, R. G. (Other)
National Institute of General Medical Sciences
7/1/22 → 6/30/27
Project: Research project
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Role of mRNA-binding protein tristetraprolin in cardiac mRNA regulation and the development of heart failure
Ardehali, H. (PD/PI) & Ardehali, H. (PD/PI)
National Heart, Lung, and Blood Institute
12/15/21 → 11/30/25
Project: Research project
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CardioExcyte 96 System for Pharmacology Research at Northwestern University
George, A. L. (PD/PI), Abdulkadir, S. A. (Other), Ardehali, H. (Other), Arora, R. K. (Other), Burridge, P. (Other), Kearney, J. A. (Other), McNally, E. M. (Other), Schiltz, G. E. (Other), Silverman, R. B. (Other), Watterson, D. M. (Other) & Wilsbacher, L. D. (Other)
Office of the Director, National Institutes of Health
6/15/20 → 6/30/25
Project: Research project
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Mechanistic insights into the role of mitochondrial iron in doxorubicin-induced cardiomyopathy using human induced pluripotent stem cells
Ardehali, H. (PD/PI), Ardehali, H. (PD/PI), Burridge, P. (Co-Investigator) & Burridge, P. (Co-Investigator)
National Heart, Lung, and Blood Institute
3/15/20 → 2/28/25
Project: Research project
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Targeted Approaches for Prevention and Treatment of Anthracycline-Induced Cardiotoxicity
Ardehali, H. (PD/PI) & Ardehali, H. (PD/PI)
1/1/20 → 12/31/24
Project: Research project
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Intravenous Iron Repletion for Patients With Heart Failure and Iron Deficiency: JACC State-of-the-Art Review
Cheema, B., Chokshi, A., Orimoloye, O. & Ardehali, H., Jun 25 2024, In: Journal of the American College of Cardiology. 83, 25, p. 2674-2689 16 p.Research output: Contribution to journal › Review article › peer-review
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DNA Damage and Nuclear Morphological Changes in Cardiac Hypertrophy Are Mediated by SNRK Through Actin Depolymerization
Stanczyk, P. J., Tatekoshi, Y., Shapiro, J. S., Nayudu, K., Chen, Y., Zilber, Z., Schipma, M., De Jesus, A., Mahmoodzadeh, A., Akrami, A., Chang, H. C. & Ardehali, H., Nov 14 2023, In: Circulation. 148, 20, p. 1582-1592 11 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Ferric derisomaltose therapy and heart failure: implications and molecular insights
Sawicki, K. T. & Ardehali, H., Jan 2023, In: Nature Cardiovascular Research. 2, 1, p. 3-5 3 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access1 Scopus citations -
Iron drives anabolic metabolism through active histone demethylation and mTORC1
Shapiro, J. S., Chang, H. C., Tatekoshi, Y., Zhao, Z., Waxali, Z. S., Hong, B. J., Chen, H., Geier, J. A., Bartom, E. T., De Jesus, A., Nejad, F. K., Mahmoodzadeh, A., Sato, T., Ramos-Alonso, L., Romero, A. M., Martinez-Pastor, M. T., Jiang, S. C., Sah-Teli, S. K., Li, L. & Bentrem, D. & 8 others, , Oct 2023, In: Nature Cell Biology. 25, 10, p. 1478-1494 17 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Iron Metabolism in Cardiovascular Disease: Physiology, Mechanisms, and Therapeutic Targets
Sawicki, K. T., De Jesus, A. & Ardehali, H., Feb 3 2023, In: Circulation research. 132, 3, p. 379-396 18 p.Research output: Contribution to journal › Review article › peer-review
Open Access31 Scopus citations