Grants per year
Personal profile
Research Interests
The Liu lab studies the molecular mechanisms underlying cancer stem cells (CSCs) and metastasis through four ongoing interactive basic and translational research projects: (1) to understand CSCs in metastasis using cutting-edge single cell sequencing and CRISPR/Cas9 gene editing technologies; (2) to image CSC behavior and interactions with immune cells during metastasis using bioluminescence imaging and intravital imaging systems; (3) to target CSCs with novel therapeutics delivered by exosomes and nanoparticles; (4) to develop circulating tumor cells (CTCs) and circulating exosome-based biomarkers for cancer diagnosis, treatment monitoring, and prognosis.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Biomedical Sciences, PhD, University of Chicago
… → 2006
Medicine, MD, Air Force Medical University
… → 1995
Research interests keywords
- Breast Cancer
- Cancer Biology
- Cell Adhesion Mechanisms
- Cell Imaging
- Circulation
- Immune Regulation
- MicroRNA
- Nanotechnology
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Novel functions of PlexinB2 in circulating tumor cell clusters
Liu, H. (PD/PI), Gradishar, W. J. (Co-Investigator) & Jia, Y. (Other)
2/21/25 → 1/31/30
Project: Research project
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Liu - Develop a novel therapy with immuno- and onco-targeting dual efficacies to treat the triple negative breast cancer
Liu, H. (PD/PI)
1/1/25 → 12/31/29
Project: Research project
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Spatiotemporal analyses of human tumor-immune interactome
Liu, H. (PD/PI) & Cooper, L. A. D. (Co-Investigator)
6/1/24 → 5/31/27
Project: Research project
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Proteomic analysis and targeting of circulating tumor stem cell clusters in breast cancer
Liu, H. (PD/PI), Fang, D. (Other), Jia, Y. (Other) & Shah, A. N. (Other)
1/1/23 → 12/31/27
Project: Research project
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Clinical analysis and therapeutic development of exosomal ACE2
Liu, H. (PD/PI), Liu, H. (PD/PI), Zhang, H. (Co-Investigator) & Jia, Y. (Other)
National Institute of Allergy and Infectious Diseases
7/15/22 → 6/30/27
Project: Research project
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Circulation tumor cell isolation and enrichment technologies
Zhang, Y., Scholten, D., Qiang, W., Platanias, L. C., Gradishar, W. J., Kelley, S. O. & Liu, H., 2025, (Accepted/In press) International Review of Cell and Molecular Biology. Elsevier Inc, (International Review of Cell and Molecular Biology).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Polycomb group protein Mel18 inhibits hematopoietic stem cell self-renewal through repressing the transcription of self-renewal and proliferation genes
Cai, W., Liu, X., Barajas, S., Xiao, S., Vemula, S., Chen, H., Yang, Y., Bochers, C., Henley, D., Liu, S., Jia, Y., Hong, M., Mays, T. M., Capitano, M. L., Liu, H., Ji, P., Gao, Z., Pasini, D., Wan, J. & Yue, F. & 4 others, , Feb 2025, In: Leukemia. 39, 2, p. 296-307 12 p., 550.Research output: Contribution to journal › Article › peer-review
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Robust collection and processing for label-free single voxel proteomics
Kitata, R. B., Velickovic, M., Xu, Z., Zhao, R., Scholten, D., Chu, R. K., Orton, D. J., Chrisler, W. B., Zhang, T., Mathews, J. V., Bumgarner, B. M., Gursel, D. B., Moore, R. J., Piehowski, P. D., Liu, T., Smith, R. D., Liu, H., Wasserfall, C. H., Tsai, C. F. & Shi, T., Dec 2025, In: Nature communications. 16, 1, 547.Research output: Contribution to journal › Article › peer-review
Open Access -
Targeted intracellular delivery of molecular cargo to hypoxic human breast cancer stem cells
Makela, A. V., Tundo, A., Liu, H., Schneider, D., Hermiston, T., Khodakivskyi, P., Goun, E. & Contag, C. H., 2025, (Accepted/In press) In: Cancer Communications.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Correction to: Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP) (Nature Cell Biology, (2023), 25, 8, (1089-1100), 10.1038/s41556-023-01194-w)
HuBMAP Consortium, May 2024, In: Nature Cell Biology. 26, 5, p. 839 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access1 Scopus citations