Grants per year
Personal profile
Research Interests
The Liu lab studies the molecular mechanisms underlying cancer stem cells (CSCs) and metastasis through four ongoing interactive basic and translational research projects: (1) to understand CSCs in metastasis using cutting-edge single cell sequencing and CRISPR/Cas9 gene editing technologies; (2) to image CSC behavior and interactions with immune cells during metastasis using bioluminescence imaging and intravital imaging systems; (3) to target CSCs with novel therapeutics delivered by exosomes and nanoparticles; (4) to develop circulating tumor cells (CTCs) and circulating exosome-based biomarkers for cancer diagnosis, treatment monitoring, and prognosis.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Biomedical Sciences, PhD, University of Chicago
… → 2006
Medicine, MD, Air Force Medical University
… → 1995
Research interests keywords
- Breast Cancer
- Cancer Biology
- Cell Adhesion Mechanisms
- Cell Imaging
- Circulation
- Immune Regulation
- MicroRNA
- Nanotechnology
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Proteomic analysis and targeting of circulating tumor stem cell clusters in breast cancer
Liu, H. (PD/PI), Fang, D. (Other), Jia, Y. (Other) & Shah, A. N. (Other)
1/1/23 → 12/31/27
Project: Research project
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Clinical analysis and therapeutic development of exosomal ACE2
Liu, H. (PD/PI), Liu, H. (PD/PI), Zhang, H. (Co-Investigator) & Jia, Y. (Other)
National Institute of Allergy and Infectious Diseases
7/15/22 → 6/30/27
Project: Research project
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Molecular mechanisms underlying circulating tumor cell aggregation
Liu, H. (PD/PI), Liu, H. (PD/PI), Cristofanilli, M. (Co-Investigator) & Cristofanilli, M. (Co-Investigator)
4/11/20 → 3/31/25
Project: Research project
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How Circulating Melanoma Cells Usurp the Leukocyte Transmigration Mechanism for Successful Metastasis
Muller, W. A. (PD/PI), Muller, W. A. (PD/PI), Fu, T. (Co-Investigator), Fu, T. (Co-Investigator), Liu, H. (Co-Investigator) & Liu, H. (Co-Investigator)
4/1/19 → 3/31/25
Project: Research project
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Flexible Hybrid Cloud Infrastructure for Seamless Management of HuBMAP Resources
Liu, H. (PD/PI)
Carnegie Mellon University, Office of the Director, National Institutes of Health
5/31/22 → 8/27/22
Project: Research project
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Correction to: Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP) (Nature Cell Biology, (2023), 25, 8, (1089-1100), 10.1038/s41556-023-01194-w)
HuBMAP Consortium, May 2024, In: Nature Cell Biology. 26, 5, p. 839 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access1 Scopus citations -
Multi-omic features and clustering phenotypes of circulating tumor cells associated with metastasis and clinical outcomes
Singh, A., Liu, H. & El-Shennawy, L., 2024, (Accepted/In press) International Review of Cell and Molecular Biology. Elsevier Inc, (International Review of Cell and Molecular Biology).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Northwestern University resource and education development initiatives to advance collaborative artificial intelligence across the learning health system
Luo, Y., Mao, C., Sanchez-Pinto, L. N., Ahmad, F. S., Naidech, A., Rasmussen, L., Pacheco, J. A., Schneider, D., Mithal, L. B., Dresden, S., Holmes, K., Carson, M., Shah, S. J., Khan, S., Clare, S., Wunderink, R. G., Liu, H., Walunas, T., Cooper, L. & Yue, F. & 14 others, , Jul 2024, In: Learning Health Systems. 8, 3, e10417.Research output: Contribution to journal › Article › peer-review
Open Access -
PRL2 Phosphatase Promotes Oncogenic KIT Signaling in Leukemia Cells through Modulating CBL Phosphorylation
Chen, H., Bai, Y., Kobayashi, M., Xiao, S., Barajas, S., Cai, W., Chen, S., Miao, J., Meke, F. N., Yao, C., Yang, Y., Strube, K., Satchivi, O., Sun, J., Ronnstrand, L., Croop, J. M., Boswell, H. S., Jia, Y., Liu, H. & Li, L. S. & 10 others, , Jan 2024, In: Molecular Cancer Research. 22, 1, p. 94-103 10 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP)
HuBMAP Consortium, Aug 2023, In: Nature Cell Biology. 25, 8, p. 1089-1100 12 p.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations