Grants per year
Personal profile
Research Interests
The Liu lab studies the molecular mechanisms underlying cancer stem cells (CSCs) and metastasis through four ongoing interactive basic and translational research projects: (1) to understand CSCs in metastasis using cutting-edge single cell sequencing and CRISPR/Cas9 gene editing technologies; (2) to image CSC behavior and interactions with immune cells during metastasis using bioluminescence imaging and intravital imaging systems; (3) to target CSCs with novel therapeutics delivered by exosomes and nanoparticles; (4) to develop circulating tumor cells (CTCs) and circulating exosome-based biomarkers for cancer diagnosis, treatment monitoring, and prognosis.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Biomedical Sciences, PhD, The University of Chicago
… → 2006
Medicine, MD, Fourth Military Medical University
… → 1995
Research interests keywords
- Breast Cancer
- Cancer Biology
- Cell Adhesion Mechanisms
- Cell Imaging
- Circulation
- Immune Regulation
- MicroRNA
- Nanotechnology
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Proteomic analysis and targeting of circulating tumor stem cell clusters in breast cancer
Liu, H., Fang, D., Jia, Y. & Shah, A. N.
1/1/23 → 12/31/27
Project: Research project
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Clinical analysis and therapeutic development of exosomal ACE2
Liu, H., Ison, M. G. & Zhang, H.
National Institute of Allergy and Infectious Diseases
7/15/22 → 6/30/27
Project: Research project
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A streamlined platform for phosphoproteome mapping of human tissues
Liu, H., Arvanitis, C. & Wei, J.
Battelle Memorial Institute, Pacific Northwest National Laboratory, National Cancer Institute
11/23/20 → 8/31/24
Project: Research project
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Molecular mechanisms underlying circulating tumor cell aggregation
Liu, H. & Cristofanilli, M.
4/11/20 → 3/31/25
Project: Research project
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Imager/scanner subproject Molecular mechanisms underlying circulating tumor cell aggregation
4/11/20 → 3/31/25
Project: Research project
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Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP)
HuBMAP Consortium, Aug 2023, In: Nature Cell Biology. 25, 8, p. 1089-1100 12 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
PRL2 phosphatase enhances oncogenic FLT3 signaling via dephosphorylation of the E3 ubiquitin ligase CBL at tyrosine 371
Chen, H., Bai, Y., Kobayashi, M., Xiao, S., Cai, W., Barajas, S., Chen, S., Miao, J., Meke, F. N., Vemula, S., Ropa, J. P., Croop, J. M., Boswell, H. S., Wan, J., Jia, Y., Liu, H., Li, L. S., Altman, J. K., Eklund, E. A., Ji, P., & 6 others, Jan 19 2023, In: Blood. 141, 3, p. 244-259 16 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Unique molecular signatures sustained in circulating monocytes and regulatory T cells in convalescent COVID-19 patients
Hoffmann, A. D., Weinberg, S. E., Swaminathan, S., Chaudhuri, S., Almubarak, H. F., Schipma, M. J., Mao, C., Wang, X., El-Shennawy, L., Dashzeveg, N. K., Wei, J., Mehl, P. J., Shihadah, L. J., Wai, C. M., Ostiguin, C., Jia, Y., D'Amico, P., Wang, N. R., Luo, Y., Demonbreun, A. R., & 3 others, Jul 2023, In: Clinical Immunology. 252, 109634.Research output: Contribution to journal › Article › peer-review
Open Access -
Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2
El-Shennawy, L., Hoffmann, A. D., Dashzeveg, N. K., McAndrews, K. M., Mehl, P. J., Cornish, D., Yu, Z., Tokars, V. L., Nicolaescu, V., Tomatsidou, A., Mao, C., Felicelli, C. J., Tsai, C. F., Ostiguin, C., Jia, Y., Li, L., Furlong, K., Wysocki, J., Luo, X., Ruivo, C. F., & 16 others, Dec 2022, In: Nature communications. 13, 1, 405.Research output: Contribution to journal › Article › peer-review
Open Access60 Scopus citations -
Ductal Carcinoma In Situ of Breast: From Molecular Etiology to Therapeutic Management
Hophan, S. L., Odnokoz, O., Liu, H., Luo, Y., Khan, S., Gradishar, W., Zhou, Z., Badve, S., Torres, M. A. & Wan, Y., Apr 1 2022, In: Endocrinology (United States). 163, 4, bqac027.Research output: Contribution to journal › Review article › peer-review
3 Scopus citations