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2020

Disordered chromatin packing regulates phenotypic plasticity

Virk, R. K. A., Wu, W., Almassalha, L. M., Bauer, G. M., Li, Y., VanDerway, D., Frederick, J., Zhang, D., Eshein, A., Roy, H. K., Szleifer, I. & Backman, V., Jan 8 2020, In : Science Advances. 6, 2, eaax6232.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Dynamic Crowding Regulates Transcription

Shim, A. R., Nap, R. J., Huang, K., Almassalha, L. M., Matusda, H., Backman, V. & Szleifer, I., May 5 2020, In : Biophysical Journal. 118, 9, p. 2117-2129 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

Physical and data structure of 3D genome

Huang, K., Li, Y., Shim, A. R., Virk, R. K. A., Agrawal, V., Eshein, A., Nap, R. J., Almassalha, L. M., Backman, V. & Szleifer, I., Jan 10 2020, In : Science Advances. 6, 2, eaay4055.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Voltage-Triggered Structural Switching of Polyelectrolyte-Modified Nanochannels

Perez Sirkin, Y. A., Szleifer, I. & Tagliazucchi, M., Jan 1 2020, (Accepted/In press) In : Macromolecules.

Research output: Contribution to journalArticle

1 Scopus citations
2019

Adsorption and insertion of polyarginine peptides into membrane pores: The trade-off between electrostatics, acid-base chemistry and pore formation energy

Ramírez, P. G., Del Pópolo, M. G., Vila, J. A., Szleifer, I. & Longo, G. S., Sep 15 2019, In : Journal of Colloid And Interface Science. 552, p. 701-711 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Classification of RNA backbone conformations into rotamers using 13C' chemical shifts: Exploring how far we can go

Icazatti, A. A., Loyola, J. M., Szleifer, I., Vila, J. A. & Martin, O. A., 2019, In : PeerJ. 2019, 10, 7904.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Effect of collagenase–gelatinase ratio on the mechanical properties of a collagen fibril: a combined Monte Carlo–molecular dynamics study

Powell, B., Malaspina, D. C., Szleifer, I. G. & Dhaher, Y. Y., Dec 1 2019, In : Biomechanics and Modeling in Mechanobiology. 18, 6, p. 1809-1819 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Effect of Polymer Surface Modification of Superparamagnetic Iron Oxide Nanoparticle Dispersions in High Salinity Environments

Yu, J., Nap, R. J., Szleifer, I. & Wong, J. Y., Dec 3 2019, In : Langmuir. 35, 48, p. 15864-15871 8 p.

Research output: Contribution to journalArticle

Multimodal interference-based imaging of nanoscale structure and macromolecular motion uncovers UV induced cellular paroxysm

Gladstein, S., Almassalha, L. M., Cherkezyan, L., Chandler, J. E., Eshein, A., Eid, A., Zhang, D., Wu, W., Bauer, G. M., Stephens, A. D., Morochnik, S., Subramanian, H., Marko, J. F., Ameer, G. A., Szleifer, I. & Backman, V., Dec 1 2019, In : Nature communications. 10, 1, 1652.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Nanocompartmentalization of the Nuclear Pore Lumen

Huang, K., Tagliazucchi, M., Park, S. H., Rabin, Y. & Szleifer, I., Jan 1 2019, (Accepted/In press) In : Biophysical Journal.

Research output: Contribution to journalArticle

PH-Dependent structure of water-exposed surfaces of CdSe quantum dots

Westmoreland, D. E., Nap, R. J., Arcudi, F., Szleifer, I. & Weiss, E. A., Jan 1 2019, In : Chemical Communications. 55, 38, p. 5435-5438 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Preservation of cellular nano-architecture by the process of chemical fixation for nanopathology

Zhou, X., Gladstein, S., Almassalha, L. M., Li, Y., Eshein, A., Cherkezyan, L., Viswanathan, P., Subramanian, H., Szleifer, I. & Backman, V., Jul 1 2019, In : PloS one. 14, 7, e0219006.

Research output: Contribution to journalArticle

Open Access
2018

13Check_RNA: A tool to evaluate 13 C chemical shift assignments of RNA

Icazatti, A. A., Martin, O. A., Villegas, M., Szleifer, I. & Vila, J. A., 2018, In : Bioinformatics. 34, 23, p. 4124-4126 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

A thermoresponsive, citrate-based macromolecule for bone regenerative engineering

Morochnik, S., Zhu, Y., Duan, C., Cai, M., Reid, R. R., He, T. C., Koh, J., Szleifer, I. & Ameer, G. A., Jun 2018, In : Journal of Biomedical Materials Research - Part A. 106, 6, p. 1743-1752 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Competitive calcium ion binding to end-tethered weak polyelectrolytes

Nap, R. J., Park, S. H. & Szleifer, I., Jan 1 2018, In : Soft Matter. 14, 12, p. 2365-2378 14 p.

Research output: Contribution to journalArticle

14 Scopus citations

Covalent-supramolecular hybrid polymers as muscle-inspired anisotropic actuators

Chin, S. M., Synatschke, C. V., Liu, S., Nap, R. J., Sather, N. A., Wang, Q., Álvarez, Z., Edelbrock, A. N., Fyrner, T., Palmer, L. C., Szleifer, I., Olvera De La Cruz, M. & Stupp, S. I., Dec 1 2018, In : Nature communications. 9, 1, 2395.

Research output: Contribution to journalArticle

39 Scopus citations
5 Scopus citations
8 Scopus citations

Insights into the Role of Counterions on Polyelectrolyte-Modified Nanopore Accessibility

Silies, L., Gonzalez Solveyra, E., Szleifer, I. & Andrieu-Brunsen, A., May 22 2018, In : Langmuir. 34, 20, p. 5943-5953 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

In silico study of principal sex hormone effects on post-injury synovial inflammatory response

Powell, B., Szleifer, I. G. & Dhaher, Y. Y., Dec 2018, In : PloS one. 13, 12, e0209582.

Research output: Contribution to journalArticle

1 Scopus citations

Modulation of Polyelectrolyte Adsorption on Nanoparticles and Nanochannels by Surface Curvature

Gilles, F. M., Boubeta, F. M., Azzaroni, O., Szleifer, I. & Tagliazucchi, M., Mar 29 2018, In : Journal of Physical Chemistry C. 122, 12, p. 6669-6677 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Routes for nanoparticle translocation through polymer-brush-modified nanopores

Tagliazucchi, M., Huang, K. & Szleifer, I., Jun 14 2018, In : Journal of Physics Condensed Matter. 30, 27, 274006.

Research output: Contribution to journalArticle

5 Scopus citations

The interplay of nanointerface curvature and calcium binding in weak polyelectrolyte-coated nanoparticles

Nap, R. J., Gonzalez Solveyra, E. & Szleifer, I., May 2018, In : Biomaterials Science. 6, 5, p. 1048-1058 11 p.

Research output: Contribution to journalArticle

9 Scopus citations
2017

Behavior of ligand binding assays with crowded surfaces: Molecular model of antigen capture by antibody-conjugated nanoparticles

Malaspina, D. C., Longo, G. & Szleifer, I., Sep 2017, In : PloS one. 12, 9, e0185518.

Research output: Contribution to journalArticle

10 Scopus citations

Colocalization of cellular nanostructure using confocal fluorescence and partial wave spectroscopy

Chandler, J. E., Stypula-Cyrus, Y., Almassalha, L., Bauer, G., Bowen, L., Subramanian, H., Szleifer, I. & Backman, V., Mar 1 2017, In : Journal of Biophotonics. 10, 3, p. 377-384 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Design of Multifunctional Nanogate in Response to Multiple External Stimuli Using Amphiphilic Diblock Copolymer

Huang, K. & Szleifer, I., May 10 2017, In : Journal of the American Chemical Society. 139, 18, p. 6422-6430 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

Macrogenomic engineering via modulation of the scaling of chromatin packing density

Almassalha, L. M., Bauer, G. M., Wu, W., Cherkezyan, L., Zhang, D., Kendra, A., Gladstein, S., Chandler, J. E., Vanderway, D., Seagle, B. L. L., Ugolkov, A., Billadeau, D. D., O'Halloran, T. V., Mazar, A. P., Roy, H. K., Szleifer, I., Shahabi, S. & Backman, V., Nov 1 2017, In : Nature Biomedical Engineering. 1, 11, p. 902-913 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

Mechanical properties of a collagen fibril under simulated degradation

Malaspina, D. C., Szleifer, I. G. & Dhaher, Y. Y., Nov 1 2017, In : Journal of the Mechanical Behavior of Biomedical Materials. 75, p. 549-557 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Structural behavior of competitive temperature and pH-responsive tethered polymer layers

Morochnik, S., Nap, R. J., Ameer, G. A. & Szleifer, I., 2017, In : Soft Matter. 13, 37, p. 6322-6331 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

The effects of chemical fixation on the cellular nanostructure

Li, Y., Almassalha, L. M., Chandler, J. E., Zhou, X., Stypula-Cyrus, Y. E., Hujsak, K. A., Roth, E. W., Bleher, R., Subramanian, H., Szleifer, I., Dravid, V. P. & Backman, V., Sep 15 2017, In : Experimental Cell Research. 358, 2, p. 253-259 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

The global relationship between chromatin physical topology, fractal structure, and gene expression

Almassalha, L. M., Tiwari, A., Ruhoff, P. T., Stypula-Cyrus, Y., Cherkezyan, L., Matsuda, H., Dela Cruz, M. A., Chandler, J. E., White, C., Maneval, C., Subramanian, H., Szleifer, I., Roy, H. K. & Backman, V., Jan 24 2017, In : Scientific reports. 7, 41061.

Research output: Contribution to journalArticle

32 Scopus citations
2016

Anisotropic surface functionalization of Au nanorods driven by molecular architecture and curvature effects

Solveyra, E. G., Tagliazucchi, M. & Szleifer, I., 2016, In : Faraday Discussions. 191, p. 351-372 22 p.

Research output: Contribution to journalArticle

7 Scopus citations

Controlling swelling/deswelling of stimuli-responsive hydrogel nanofilms in electric fields

Longo, G. S., Olvera De La Cruz, M. & Szleifer, I., Jan 1 2016, In : Soft Matter. 12, 40, p. 8359-8366 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Controlling the hydration rate of a hydrophilic matrix in the core of an intravaginal ring determines antiretroviral release

Teller, R. S., Malaspina, D. C., Rastogi, R., Clark, J. T., Szleifer, I. G. & Kiser, P., Feb 28 2016, In : Journal of Controlled Release. 224, p. 176-183 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Differential mechanisms of tenofovir and tenofovir disoproxil fumarate cellular transport and implications for topical preexposure prophylaxis

Taneva, E., Crooker, K., Park, S. H., Su, J. T., Ott, A., Cheshenko, N., Szleifer, I., Kiser, P. F., Frank, B., Mesquita, P. M. M. & Herold, B. C., Mar 2016, In : Antimicrobial agents and chemotherapy. 60, 3, p. 1667-1675 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Dynamics of dissipative self-assembly of particles interacting through oscillatory forces

Tagliazucchi, M. & Szleifer, I., Jan 1 2016, In : Faraday Discussions. 186, p. 399-418 20 p.

Research output: Contribution to journalArticle

9 Scopus citations

Enhanced binding of antibodies generated during chronic HIV infection to mucus component MUC16

Gunn, B. M., Shansab, M., Schneider, J. R., Bastian, A. R., Fahrbach, K. M., SmithIV, A. D., Mahan, A. E., Karim, M. M., Licht, A. F., Zvonar, I., Tedesco, J., Anderson, M. R., Chapel, A., Suscovich, T. J., Malaspina, D. C., Streeck, H., Walker, B. D., Kim, A., Lauer, G., Altfeld, M. & 6 others, Pillai, S., Szleifer, I., Kelleher, N. L., Kiser, P. F., Hope, T. J. & Alter, G., Nov 1 2016, In : Mucosal Immunology. 9, 6, p. 1549-1558 10 p.

Research output: Contribution to journalArticle

29 Scopus citations

Ionic Conductance of Polyelectrolyte-Modified Nanochannels: Nanoconfinement Effects on the Coupled Protonation Equilibria of Polyprotic Brushes

Gilles, F. M., Tagliazucchi, M., Azzaroni, O. & Szleifer, I., Mar 17 2016, In : Journal of Physical Chemistry C. 120, 9, p. 4789-4798 10 p.

Research output: Contribution to journalArticle

26 Scopus citations

Label-free imaging of the native, living cellular nanoarchitecture using partial-wave spectroscopic microscopy

Almassalha, L. M., Bauer, G. M., Chandler, J. E., Gladstein, S., Cherkezyan, L., Stypula-Cyrus, Y., Weinberg, S., Zhang, D., Ruhoff, P. T., Roy, H. K., Subramanian, H., Chandel, N. S., Szleifer, I. & Backman, V., Oct 18 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 42, p. E6372-E6381

Research output: Contribution to journalArticle

31 Scopus citations

Using electron microscopy to calculate optical properties of biological samples

Wu, W., Radosevich, A. J., Eshein, A., Nguyen, T. Q., Yi, J., Cherkezyan, L., Roy, H. K., Szleifer, I. & Backman, V., Nov 1 2016, In : Biomedical Optics Express. 7, 11, p. 4749-4762 14 p., #275078.

Research output: Contribution to journalArticle

7 Scopus citations
2015

How Does Confinement Change Ligand-Receptor Binding Equilibrium? Protein Binding in Nanopores and Nanochannels

Tagliazucchi, M. & Szleifer, I. G., Oct 7 2015, In : Journal of the American Chemical Society. 137, 39, p. 12539-12551 13 p.

Research output: Contribution to journalArticle

26 Scopus citations

Lysozyme adsorption in pH-responsive hydrogel thin-films: the non-trivial role of acid-base equilibrium

Narambuena, C. F., Longo, G. S. & Szleifer, I., Jul 9 2015, In : Soft Matter. 11, 33, p. 6669-6679 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Membrane curvature enables N-Ras lipid anchor sorting to liquid-ordered membrane phases

Larsen, J. B., Jensen, M. B., Bhatia, V. K., Pedersen, S. L., Bjørnholm, T., Iversen, L., Uline, M., Szleifer, I., Jensen, K. J., Hatzakis, N. S. & Stamou, D., Mar 2015, In : Nature Chemical Biology. 11, 3, p. 192-194 3 p.

Research output: Contribution to journalArticle

65 Scopus citations

Mesoporous hybrid thin film membranes with PMETAC@Silica architectures: Controlling ionic gating through the tuning of polyelectrolyte density

Andrieu-Brunsen, A., Micoureau, S., Tagliazucchi, M., Szleifer, I., Azzaroni, O. & Soler-Illia, G. J. A. A., Feb 10 2015, In : Chemistry of Materials. 27, 3, p. 808-821 14 p.

Research output: Contribution to journalArticle

29 Scopus citations

Molecular and Thermodynamic Factors Explain the Passivation Properties of Poly(ethylene glycol)-Coated Substrate Surfaces against Fluorophore-Labeled DNA Oligonucleotides

Ren, C. L., Schlapak, R., Hager, R., Szleifer, I. G. & Howorka, S., Oct 27 2015, In : Langmuir. 31, 42, p. 11491-11501 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Molecular Design of Antifouling Polymer Brushes Using Sequence-Specific Peptoids

Lau, K. H. A., Sileika, T. S., Park, S. H., Sousa, A. M. L., Burch, P., Szleifer, I. & Messersmith, P. B., Jan 1 2015, In : Advanced Materials Interfaces. 2, 1, 1400225.

Research output: Contribution to journalArticle

42 Scopus citations

Molecular Dynamics Simulation of Ice Indentation by Model Atomic Force Microscopy Tips

Gelman Constantin, J., Carignano, M. A., Corti, H. R. & Szleifer, I. G., Nov 9 2015, In : Journal of Physical Chemistry C. 119, 48, p. 27118-27124 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Molecular dynamics simulations of anchored viral peptide interactions

Yacoub, T. J. & Szleifer, I., Jun 1 2015, In : Biointerphases. 10, 2, 029513.

Research output: Contribution to journalArticle

Salt Pumping by Voltage-Gated Nanochannels

Tagliazucchi, M. & Szleifer, I. G., Aug 25 2015, In : Journal of Physical Chemistry Letters. 6, 18, p. 3534-3539 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

The role of steric interactions in dispersion of carbon nanotubes by poly(3-alkyl thiophenes) in organic solvents

Bar-Hen, A., Bounioux, C., Yerushalmi-Rozen, R., Gonzalez Solveyra, E. & Szleifer, I., Aug 5 2015, In : Journal of Colloid And Interface Science. 452, p. 62-68 7 p.

Research output: Contribution to journalArticle

11 Scopus citations