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Ikuo Hirano

  • 10345 Citations
1992 …2023

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Personal profile

Research Interests

Dr. Hirano is Professor of Medicine at Northwestern University Feinberg School of Medicine. He attended college at Yale University, medical school at the University of Pennsylvania and completed his medical residency and GI fellowship at Beth Israel Hospital in Boston. He took a faculty position at the West Roxbury VA Medical Center and Harvard Medical School working in esophageal swallowing physiology before coming to Northwestern in 1998. He is currently serving as Vice-Chair for the American Gastroenterological Association’s Esophageal, Gastric and Duodenal (EGD) section, site principal investigator for the Consortium of Eosinophilic Gastrointestinal disease Researchers (CEGIR) and the educational co-chair for International Gastrointestinal Eosinophil Researchers (TIGERS). Dr. Hirano has written over 150 scientific papers and textbook chapters that focus on esophageal and swallowing disorders. He has active grant support from the NIH and FDA. Dr. Hirano is on the editorial board for Clinical Gastroenterology and Hepatology. He received the Northwestern University School of Medicine Award for Outstanding Achievement in Gastroenterology in 2002 and Distinguished Service Award in 2013. Dr. Hirano has been recognized as one of the Chicago area’s “Top Doctors” by the Chicago Consumer’s Checkbook and by Best Doctors in America.

Eosinophilic Esophagitis, Eosinophilic Gastroenteritis, Swallowing disorders

Eosinophilic Esophagitis, Eosinophilic Gastroenteritis, Esophageal motility disorders, Gastroesophageal reflux disease, Swallowing disorders

Certifications and Licenses

Gastroenterology

Training Experience

1992Residency, Beth Israel Deaconess Medical Center, Boston
1995Fellowship, Beth Israel Deaconess Medical Center, Boston

Education/Academic qualification

MD, University of Pennsylvania

… → 1990

Research interests

  • Digestive System (including gallbladder and liver)

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Grants

Prot#18-0431: A Multi-Center, Randomized, Double-Blind, Parallel-Arm, Placebo-Controlled Trial of Mepolizumab for Treatment of Adults and Adolescents with Active Eosinophilic Esophagitis and Dysphagia-Predominant Symptoms

Hirano, I.

University of North Carolina at Chapel Hill, GlaxoSmithKline LLC

2/18/20 → 2/18/23

Project: Research project

Protocol R668-EE-1774: A Phase 3, Randomized, 3-Part Study To Investigate The Efficacy And Safety Of Dupilumab In Adult And Adolescent Patients With Eosinophilic Esophagitis.

Hirano, I.

inVentiv Health Clinical, Regeneron Pharmaceuticals, Inc.

5/1/19 → 5/1/22

Project: Research project

Protocol Title: AK002-003X : A Phase 2, Multicenter, Open-Label, Extension Study to Evaluate the Safety and Tolerability of AK002 in Patients with Eosinophilic Gastritis and/or Eosinophilic Gastroenteritis

Hirano, I.

Allakos, Inc.

3/19/19 → 3/19/22

Project: Research project

Prot#AK002-003: A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study To Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamic Effect of AK002 in Patients with Eosinophilic Gastritis (EG) and/or Eosinophilic Gastroenteritis

Hirano, I.

Allakos, Inc.

8/27/18 → 8/27/21

Project: Research project

Disordered Tissue Biomechanics as a Driver of Esophageal Disease

Budinger, G. S., Carlson, D. A., Ciolino, J. D., Espinosa, H. D., Gonsalves, N. P., Hinchcliff, M. E., Hirano, I., Kahrilas, P. J., Pandolfino, J. E., Passman, R. S., Patankar, N. A., Taft, T. N., Tetreault, M. & Yang, G.

National Institute of Diabetes, Digestive and Kidney Diseases

7/15/18 → 6/30/23

Project: Research project

    • Research Output

    Advancing patient care through the Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR)

    Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR), Jan 2020, In : Journal of Allergy and Clinical Immunology. 145, 1, p. 28-37 10 p.

    Research output: Contribution to journal › Article

    • Approaches and Challenges to Management of Pediatric and Adult Patients With Eosinophilic Esophagitis

    Hirano, I. & Furuta, G. T., Mar 2020, In : Gastroenterology. 158, 4, p. 840-851 12 p.

    Research output: Contribution to journal › Review article

    Open Access

    • Clinical relevance of esophageal subepithelial activity in eosinophilic esophagitis

    Hirano, I., Mar 1 2020, In : Journal of Gastroenterology. 55, 3, p. 249-260 12 p.

    Research output: Contribution to journal › Review article

    Open Access

    • Efficacy of Dupilumab in a Phase 2 Randomized Trial of Adults With Active Eosinophilic Esophagitis

    Hirano, I., Dellon, E. S., Hamilton, J. D., Collins, M. H., Peterson, K., Chehade, M., Schoepfer, A. M., Safroneeva, E., Rothenberg, M. E., Falk, G. W., Assouline-Dayan, Y., Zhao, Q., Chen, Z., Swanson, B. N., Pirozzi, G., Mannent, L., Graham, N. M. H., Akinlade, B., Stahl, N., Yancopoulos, G. D. & 1 others, Radin, A., Jan 2020, In : Gastroenterology. 158, 1, p. 111-122.e10

    Research output: Contribution to journal › Article

    Open Access
    • 8 Scopus citations

    Emerging therapies for eosinophilic esophagitis

    Greuter, T., Hirano, I. & Dellon, E. S., Jan 2020, In : Journal of Allergy and Clinical Immunology. 145, 1, p. 38-45 8 p.

    Research output: Contribution to journal › Article

    • 2 Scopus citations