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Irina V Balyasnikova

  • 2730 Citations
1994 …2023

Research output per year

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Personal profile

Research Interests

My research focus is on the development of novel targeted approaches for the treatment of malignant brain tumors. In particular, I am interested in developing and utilizing antibodies and genetically engineered variants against tumor-specific antigens in order to enhance and deliver therapeutics specifically to brain and other tumors. Another area of my interest is in the development of stem cells as therapeutic carriers. It includes investigation of various routes of delivery, mechanism of migration of stem cells and non-invasive tracking of therapeutic stem cell to solid brain tumors and metastatic lesions.

Training Experience

1997Postdoctoral Fellowship, University of Pennsylvania
2000Postdoctoral Fellowship, University of Illinois, Chicago

Education/Academic qualification

PhD, National Cardiology Research Center, Moscow, Russia

… → 1994

Research interests

  • Biologic Therapies
  • Brain Cancer / Nervous System Cancer
  • Molecular Imaging

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Grants

Neural Stem Cell Carriers for Glioblastoma Immunotherapy

Balyasnikova, I. V., Horbinski, C. M. & James, C. D.

National Institute of Neurological Disorders and Stroke

6/1/19 → 5/31/21

Project: Research project

Genetic Approaches to Optimize CAR T cells for Glioblastoma Therapy

Balyasnikova, I. V., Horbinski, C. M. & Lesniak, M. S.

National Institute of Neurological Disorders and Stroke

9/30/18 → 8/31/23

Project: Research project

    • Non-invasive immunoPET imaging for the detection of HER2+ status in preclinical model of brain metastases of breast cancer.

    Balyasnikova, I. V.

    Northwestern Memorial Hospital

    9/1/18 → 8/31/20

    Project: Research project

    • SPORE for Translational Approaches to Brain Cancer

    Ahmed, A. U., Balyasnikova, I. V., Bartom, E. T., Brat, D. J., Chandler, J. P., Cheng, S., Horbinski, C. M., Hu, B., James, C. D., Kumthekar, P. U., Leikin, R. G., Lesniak, M. S., Liu, B. P., Lukas, R. V., Platanias, L. C., Sachdev, S., Scholtens, D. M., Stegh, A. H., Stupp, R. & Wainwright, D. A.

    National Cancer Institute

    8/17/18 → 7/31/23

    Project: Research project

    • C-081: The Connectome of Newly Born Neurons

    Balyasnikova, I. V.

    Searle Funds at The Chicago Community Trust

    1/1/17 → 12/31/21

    Project: Research project

    Research Output

    • 2730 Citations
    • 80 Article
    • 3 Review article
    • 2 Comment/debate

    Current state of clinical trials in breast cancer brain metastases

    Fares, J., Kanojia, D., Cordero, A., Rashidi, A., Miska, J. M., Schwartz, C. W., Savchuk, S., Ahmed, A. U., Balyasnikova, I. V., Cristofanilli, M., Gradishar, W. J. & Lesniak, M. S., Sep 20 2019, In : Neuro-Oncology Practice. 6, 5, p. 392-401 10 p.

    Research output: Contribution to journal › Article

    • 6 Scopus citations

    Diagnostic Clinical Trials in Breast Cancer Brain Metastases: Barriers and Innovations

    Fares, J., Kanojia, D., Rashidi, A., Ahmed, A. U., Balyasnikova, I. V. & Lesniak, M. S., Dec 2019, In : Clinical breast cancer. 19, 6, p. 383-391 9 p.

    Research output: Contribution to journal › Review article

    • 3 Scopus citations

    Myeloid-derived suppressive cells promote B cell-mediated immunosuppression via transfer of PD-L1 in glioblastoma

    Lee-Chang, C., Rashidi, A., Miska, J., Zhang, P., Pituch, K. C., Hou, D., Xiao, T., Fischietti, M., Kang, S. J., Appin, C. L., Horbinski, C., Platanias, L. C., Lopez-Rosas, A., Han, Y., Balyasnikova, I. V. & Lesniak, M. S., Jan 1 2019, In : Cancer Immunology Research. 7, 12, p. 1928-1943 16 p.

    Research output: Contribution to journal › Article

    • 3 Scopus citations

    Pharmacologic modulation of nasal epithelium augments neural stem cell targeting of glioblastoma

    Spencer, D., Yu, D., Morshed, R. A., Li, G., Pituch, K. C., Gao, D. X., Bertolino, N., Procissi, D., Lesniak, M. S. & Balyasnikova, I. V., Jan 1 2019, In : Theranostics. 9, 7, p. 2071-2083 13 p.

    Research output: Contribution to journal › Article

    Open Access
    • 1 Scopus citations

    Race influences survival in glioblastoma patients with KPS ≥ 80 and associates with genetic markers of retinoic acid metabolism

    Wu, M., Miska, J., Xiao, T., Zhang, P., Kane, J. R., Balyasnikova, I. V., Chandler, J. P., Horbinski, C. M. & Lesniak, M. S., Apr 15 2019, In : Journal of Neuro-Oncology. 142, 2, p. 375-384 10 p.

    Research output: Contribution to journal › Article

    • 2 Scopus citations