Grants per year
Personal profile
Research Interests
My research focus is on the development of novel targeted approaches for the treatment of malignant brain tumors. In particular, I am interested in developing and utilizing antibodies and genetically engineered variants against tumor-specific antigens in order to enhance and deliver therapeutics specifically to brain and other tumors. Another area of my interest is in the development of stem cells as therapeutic carriers. It includes investigation of various routes of delivery, mechanism of migration of stem cells and non-invasive tracking of therapeutic stem cell to solid brain tumors and metastatic lesions.
Training Experience
| 1997 | Postdoctoral Fellowship, University of Pennsylvania |
| 2000 | Postdoctoral Fellowship, University of Illinois, Chicago |
Expertise related to UN Sustainable Devlopment Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, National Cardiology Research Center, Moscow, Russia
… → 1994
Research interests
- Biologic Therapies
- Brain Cancer / Nervous System Cancer
- Molecular Imaging
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Understanding the Behavior of Novel IL13Ralpha2-directed T cell Engager for GBM
Balyasnikova, I. V., Horbinski, C. M., James, C. D., Stupp, R., Zhang, B. & Zhang, H.
National Institute of Neurological Disorders and Stroke
4/1/21 → 3/31/26
Project: Research project
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Development of B-cell-based vaccine for Glioblastoma
Lee Chang, C., Balyasnikova, I. V., James, C. D. & Miska, J. M.
3/15/21 → 2/28/26
Project: Research project
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IL13Rα2-directed SEA/E-120 for therapeutic T cells targeting to Glioblastoma
12/1/20 → 11/30/21
Project: Research project
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Genetic Approaches to Optimize CAR T cells for Glioblastoma Therapy
Balyasnikova, I. V., Horbinski, C. M. & Lesniak, M. S.
National Institute of Neurological Disorders and Stroke
9/30/18 → 8/31/23
Project: Research project
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Activation of 4-1BBL+ B cells with CD40 agonism and IFNγ elicits potent immunity against glioblastoma
Lee-Chang, C., Miska, J., Hou, D., Rashidi, A., Zhang, P., Burga, R. A., Jusúe, I. T., Xiao, T., Arrieta, V. A., Zhang, D. Y., Lopez-Rosas, A., Han, Y., Sonabend, A. M., Horbinski, C. M., Stupp, R., Balyasnikova, I. V. & Lesniak, M. S., Jan 4 2021, In: Journal of Experimental Medicine. 218, 1Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Interfering with Metabolic Profile of Triple-Negative Breast Cancers Using Rationally Designed Metformin Prodrugs
Babak, M. V., Chong, K. R., Rapta, P., Zannikou, M., Tang, H. M., Reichert, L., Chang, M. R., Kushnarev, V., Heffeter, P., Meier-Menches, S. M., Lim, Z. C., Yap, J. Y., Casini, A., Balyasnikova, I. V. & Ang, W. H., Jun 7 2021, In: Angewandte Chemie - International Edition. 60, 24, p. 13405-13413 9 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Labeling single domain antibody fragments with 18F using a novel residualizing prosthetic agent — N-succinimidyl 3-(1-(2-(2-(2-(2-[18F]fluoroethoxy)ethoxy)ethoxy)ethyl)-1H-1,2,3-triazol-4-yl)-5-(guanidinomethyl)benzoate
Zhou, Z., McDougald, D., Meshaw, R., Balyasnikova, I., Zalutsky, M. R. & Vaidyanathan, G., Sep 1 2021, In: Nuclear Medicine and Biology. 100-101, p. 24-35 12 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Liposomal Extravasation and Accumulation in Tumors as Studied by Fluorescence Microscopy and Imaging Depend on the Fluorescent Label
Wang, G., Zannikou, M., Lofchy, L., Li, Y., Gaikwad, H., Balyasnikova, I. V. & Simberg, D., Jul 27 2021, In: ACS nano. 15, 7, p. 11880-11890 11 p.Research output: Contribution to journal › Article › peer-review
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Mesenchymal stem cells successfully deliver oncolytic virotherapy to diffuse intrinsic pontine glioma
Chastkofsky, M. I., Pituch, K. C., Katagi, H., Zannikou, M., Ilut, L., Xiao, T., Han, Y., Sonabend, A. M., Curiel, D. T., Bonner, E. R., Nazarian, J., Horbinski, C. M., James, C. D., Saratsis, A. M., Hashizume, R., Lesniak, M. S. & Balyasnikova, I. V., Mar 2021, In: Clinical Cancer Research. 27, 6, p. 1766-1777 12 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations