Irina V Balyasnikova

  • 2505 Citations
1994 …2023
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Personal profile

Research Interests

My research focus is on the development of novel targeted approaches for the treatment of malignant brain tumors. In particular, I am interested in developing and utilizing antibodies and genetically engineered variants against tumor-specific antigens in order to enhance and deliver therapeutics specifically to brain and other tumors. Another area of my interest is in the development of stem cells as therapeutic carriers. It includes investigation of various routes of delivery, mechanism of migration of stem cells and non-invasive tracking of therapeutic stem cell to solid brain tumors and metastatic lesions.

Training Experience

1997Postdoctoral Fellowship, University of Pennsylvania
2000Postdoctoral Fellowship, University of Illinois, Chicago

Education/Academic qualification

PhD, National Cardiology Research Center, Moscow, Russia

… → 1994

Research interests

  • Biologic Therapies
  • Brain Cancer / Nervous System Cancer
  • Molecular Imaging

Fingerprint Dive into the research topics where Irina V Balyasnikova is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 20 Similar Profiles
Peptidyl-Dipeptidase A Medicine & Life Sciences
Glioma Medicine & Life Sciences
Monoclonal Antibodies Medicine & Life Sciences
Brain Neoplasms Medicine & Life Sciences
Glioblastoma Medicine & Life Sciences
Neural Stem Cells Medicine & Life Sciences
Epitopes Medicine & Life Sciences
Epitope Mapping Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2015 2023

Antigen Receptors
Glioblastoma
Cell- and Tissue-Based Therapy
T-Cell Antigen Receptor
Glioma
Glioblastoma
Cell- and Tissue-Based Therapy
T-Lymphocytes
Therapeutics
varespladib methyl

Research Output 1994 2019

  • 2505 Citations
  • 77 Article
  • 2 Comment/debate
  • 2 Review article

Pharmacologic modulation of nasal epithelium augments neural stem cell targeting of glioblastoma

Spencer, D., Yu, D., Morshed, R. A., Li, G., Pituch, K. C., Gao, D. X., Bertolino, N., Procissi, D., Lesniak, M. S. & Balyasnikova, I. V., Jan 1 2019, In : Theranostics. 9, 7, p. 2071-2083 13 p.

Research output: Contribution to journalArticle

Open Access
Neural Stem Cells
Nasal Mucosa
Glioblastoma
Methimazole
Oncolytic Virotherapy
1 Citation (Scopus)
Glioblastoma
Tretinoin
Genetic Markers
African Americans
Glioma
3 Citations (Scopus)

A Dendritic Cell-Targeted Adenoviral Vector Facilitates Adaptive Immune Response Against Human Glioma Antigen (CMV-IE) and Prolongs Survival in a Human Glioma Tumor Model

Kim, J. W., Kane, J. R., Panek, W. K., Young, J. S., Rashidi, A., Yu, D., Kanojia, D., Hasan, T., Miska, J. M., Gómez-Lim, M. A., Ulasov, I., Balyasnikova, I. V., Ahmed, A. U., Wainwright, D. A. & Lesniak, M. S., Oct 14 2018, In : Neurotherapeutics. 15, 4, p. 1127-1138 12 p.

Research output: Contribution to journalArticle

Adaptive Immunity
Glioma
Dendritic Cells
Antigens
Survival
7 Citations (Scopus)

Adoptive Transfer of IL13Rα2-Specific Chimeric Antigen Receptor T Cells Creates a Pro-inflammatory Environment in Glioblastoma

Pituch, K. C., Miska, J. M., Krenciute, G., Panek, W. K., Li, G., Rodriguez-Cruz, T., Wu, M., Han, Y., Lesniak, M. S., Gottschalk, S. & Balyasnikova, I. V., Apr 4 2018, In : Molecular Therapy. 26, 4, p. 986-995 10 p.

Research output: Contribution to journalArticle

Adoptive Transfer
Glioblastoma
T-Cell Antigen Receptor
Glioma
Antigen Receptors
4 Citations (Scopus)

Intranasal delivery of stem cell-based therapies for the treatment of brain malignancies

Li, G., Bonamici, N., Dey, M., Lesniak, M. S. & Balyasnikova, I. V., Feb 1 2018, In : Expert Opinion on Drug Delivery. 15, 2, p. 163-172 10 p.

Research output: Contribution to journalReview article

Cell- and Tissue-Based Therapy
Stem Cells
Brain
Neoplasms
Brain Neoplasms