Grants per year
Personal profile
Research Interests
My research focus is on the development of novel targeted approaches for the treatment of malignant brain tumors. In particular, I am interested in developing and utilizing antibodies and genetically engineered variants against tumor-specific antigens in order to enhance and deliver therapeutics specifically to brain and other tumors. Another area of my interest is in the development of stem cells as therapeutic carriers. It includes investigation of various routes of delivery, mechanism of migration of stem cells and non-invasive tracking of therapeutic stem cell to solid brain tumors and metastatic lesions.
Training Experience
| 1997 | Postdoctoral Fellowship, University of Pennsylvania |
| 2000 | Postdoctoral Fellowship, University of Illinois, Chicago |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Cardiology, National Cardiology Research Center, Moscow, Russia
… → 1994
Research interests keywords
- Biologic Therapies
- Brain Cancer / Nervous System Cancer
- Molecular Imaging
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Project 2
Avery, R. J., Balyasnikova, I. V., Heimberger, A. B., Lukas, R. V., Procissi, D. & Sonabend Worthalter, A. M.
8/1/23 → 7/31/28
Project: Research project
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Nano-therapeutics Reprogramming of Immunosuppressive Myeloid Cells Potentiate Radiotherapy for Glioblastoma
Zhang, P., Zhang, P., Balyasnikova, I. V., Balyasnikova, I. V., Miska, J. M. & Miska, J. M.
7/26/22 → 6/30/27
Project: Research project
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Understanding the Behavior of Novel IL13Ralpha2-directed T cell Engager for GBM
Balyasnikova, I. V., Balyasnikova, I. V., Horbinski, C. M., Horbinski, C. M., James, C. D., James, C. D., Stupp, R., Stupp, R., Zhang, B., Zhang, H., Zhang, B. & Zhang, H.
National Institute of Neurological Disorders and Stroke
4/1/21 → 3/31/26
Project: Research project
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Development of B-cell-based vaccine for Glioblastoma
Lee Chang, C., Lee Chang, C., Balyasnikova, I. V., Balyasnikova, I. V., James, C. D., James, C. D., Miska, J. M. & Miska, J. M.
3/15/21 → 2/28/26
Project: Research project
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A Case Study of Chimeric Antigen Receptor T Cell Function: Donor Therapeutic Differences in Activity and Modulation with Verteporfin
Liang, J., Fang, D., Gumin, J., Najem, H., Sooreshjani, M., Song, R., Sabbagh, A., Kong, L. Y., Duffy, J., Balyasnikova, I. V., Pollack, S. M., Puduvalli, V. K. & Heimberger, A. B., Feb 2023, In: Cancers. 15, 4, 1085.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Bi-Specific Killer Cell Engager Enhances NK Cell Activity against Interleukin-13 Receptor Alpha-2 Positive Gliomas
Pawlowski, K. D., Duffy, J. T., Tiwari, A., Zannikou, M. & Balyasnikova, I. V., Jul 2023, In: Cells. 12, 13, 1716.Research output: Contribution to journal › Article › peer-review
Open Access -
Endoplasmic Reticulum Stress in the Brain Tumor Immune Microenvironment
Petrosyan, E., Fares, J., Fernandez, L. G., Yeeravalli, R., Dmello, C., Duffy, J. T., Zhang, P., Lee-Chang, C., Miska, J., Ahmed, A. U., Sonabend, A. M., Balyasnikova, I. V., Heimberger, A. B. & Lesniak, M. S., May 1 2023, In: Molecular Cancer Research. 21, 5, p. 389-396 8 p.Research output: Contribution to journal › Review article › peer-review
3 Scopus citations -
IL15 modification enables CAR T cells to act as a dual targeting agent against tumor cells and myeloid-derived suppressor cells in GBM
Zannikou, M., Duffy, J. T., Levine, R. N., Seblani, M., Liu, Q., Presser, A., Arrieta, V. A., Chen, C. J., Sonabend, A. M., Horbinski, C. M., Lee-Chang, C., Miska, J., Lesniak, M. S., Gottschalk, S. & Balyasnikova, I. V., Feb 9 2023, In: Journal for immunotherapy of cancer. 11, 2, e006239.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Modeling glioblastoma complexity with organoids for personalized treatments
Pawlowski, K. D., Duffy, J. T., Babak, M. V. & Balyasnikova, I. V., Apr 2023, In: Trends in Molecular Medicine. 29, 4, p. 282-296 15 p.Research output: Contribution to journal › Review article › peer-review
5 Scopus citations
Datasets
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CCDC 1939307: Experimental Crystal Structure Determination
Babak, M. V. (Contributor), Chong, K. R. (Contributor), Rapta, P. (Contributor), Zannikou, M. (Contributor), Tang, H. M. (Contributor), Reichert, L. (Contributor), Chang, M. R. (Contributor), Kushnarev, V. (Contributor), Heffeter, P. (Contributor), Meier-Menches, S. M. (Contributor), Lim, Z. C. (Contributor), Yap, J. Y. (Contributor), Casini, A. (Contributor), Balyasnikova, I. V. (Contributor), Ang, W. H. (Contributor) & Meier‐Menches, S. M. (Contributor), Cambridge Crystallographic Data Centre, 2022
DOI: 10.5517/ccdc.csd.cc23309k, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc23309k&sid=DataCite
Dataset
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CCDC 1939306: Experimental Crystal Structure Determination
Babak, M. V. (Contributor), Chong, K. R. (Contributor), Rapta, P. (Contributor), Zannikou, M. (Contributor), Tang, H. M. (Contributor), Reichert, L. (Contributor), Chang, M. R. (Contributor), Kushnarev, V. (Contributor), Heffeter, P. (Contributor), Meier-Menches, S. M. (Contributor), Lim, Z. C. (Contributor), Yap, J. Y. (Contributor), Casini, A. (Contributor), Balyasnikova, I. V. (Contributor), Ang, W. H. (Contributor) & Meier‐Menches, S. M. (Contributor), Cambridge Crystallographic Data Centre, 2022
DOI: 10.5517/ccdc.csd.cc23308j, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc23308j&sid=DataCite
Dataset