Grants per year
Personal profile
Research Interests
My research focus is on the development of novel targeted approaches for the treatment of malignant brain tumors. In particular, I am interested in developing and utilizing antibodies and genetically engineered variants against tumor-specific antigens in order to enhance and deliver therapeutics specifically to brain and other tumors. Another area of my interest is in the development of stem cells as therapeutic carriers. It includes investigation of various routes of delivery, mechanism of migration of stem cells and non-invasive tracking of therapeutic stem cell to solid brain tumors and metastatic lesions.
Training Experience
| 1997 | Postdoctoral Fellowship, University of Pennsylvania |
| 2000 | Postdoctoral Fellowship, University of Illinois, Chicago |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, National Cardiology Research Center, Moscow, Russia
… → 1994
Research interests
- Biologic Therapies
- Brain Cancer / Nervous System Cancer
- Molecular Imaging
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Nano-therapeutics Reprogramming of Immunosuppressive Myeloid Cells Potentiate Radiotherapy for Glioblastoma
Zhang, P., Balyasnikova, I. V. & Miska, J. M.
7/26/22 → 6/30/27
Project: Research project
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Understanding the Behavior of Novel IL13Ralpha2-directed T cell Engager for GBM
Balyasnikova, I. V., Horbinski, C. M., James, C. D., Stupp, R., Zhang, B. & Zhang, H.
National Institute of Neurological Disorders and Stroke
4/1/21 → 3/31/26
Project: Research project
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Development of B-cell-based vaccine for Glioblastoma
Lee Chang, C., Balyasnikova, I. V., James, C. D. & Miska, J. M.
3/15/21 → 2/28/26
Project: Research project
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IL13Rα2-directed SEA/E-120 for therapeutic T cells targeting to Glioblastoma
12/1/20 → 12/31/22
Project: Research project
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Combination of tucatinib and neural stem cells secreting anti-HER2 antibody prolongs survival of mice with metastatic brain cancer
Cordero, A., Ramsey, M. D., Kanojia, D., Fares, J., Petrosyan, E., Schwartz, C. W., Burga, R., Zhang, P., Rashidi, A., Castro, B., Xiao, T., Lee-Chang, C., Miska, J., Balyasnikova, I. V., Ahmed, A. U. & Lesniak, M. S., Jan 4 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 1, e2112491119.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Indocarbocyanine nanoparticles extravasate and distribute better than liposomes in brain tumors
Balyasnikova, I. V., Zannikou, M., Wang, G., Li, Y., Duffy, J. T., Levine, R. N., Seblani, M., Gaikwad, H. & Simberg, D., Sep 2022, In: Journal of Controlled Release. 349, p. 413-424 12 p.Research output: Contribution to journal › Article › peer-review
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New Approaches to Glioblastoma
Khasraw, M., Fujita, Y., Lee-Chang, C., Balyasnikova, I. V., Najem, H. & Heimberger, A. B., 2022, In: Annual review of medicine. 73, p. 279-292 14 p.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
Activation of 4-1BBL+ B cells with CD40 agonism and IFNγ elicits potent immunity against glioblastoma
Lee-Chang, C., Miska, J., Hou, D., Rashidi, A., Zhang, P., Burga, R. A., Jusúe, I. T., Xiao, T., Arrieta, V. A., Zhang, D. Y., Lopez-Rosas, A., Han, Y., Sonabend, A. M., Horbinski, C. M., Stupp, R., Balyasnikova, I. V. & Lesniak, M. S., Jan 4 2021, In: Journal of Experimental Medicine. 218, 1Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
Interfering with Metabolic Profile of Triple-Negative Breast Cancers Using Rationally Designed Metformin Prodrugs
Babak, M. V., Chong, K. R., Rapta, P., Zannikou, M., Tang, H. M., Reichert, L., Chang, M. R., Kushnarev, V., Heffeter, P., Meier-Menches, S. M., Lim, Z. C., Yap, J. Y., Casini, A., Balyasnikova, I. V. & Ang, W. H., Jun 7 2021, In: Angewandte Chemie - International Edition. 60, 24, p. 13405-13413 9 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations