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Isabelle Caroline Le Poole

  • 3795 Citations
1992 …2021
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Personal profile

Education/Academic qualification

PhD, Amsterdam University (the Netherlands)

… → 1993

MSc, Utrecht University

… → 1987

Fingerprint Dive into the research topics where Isabelle Caroline Le Poole is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 4 Similar Profiles
Vitiligo Medicine & Life Sciences
Melanocytes Medicine & Life Sciences
Melanoma Medicine & Life Sciences
Skin Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
T-cells Chemical Compounds
Neoplasms Medicine & Life Sciences
Keratinocytes Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2017 2021

5-laser 30-parameter FACSymphony-S6 SORP Cell Sorter from BD Biosciences

Abecassis, M. M., Bharat, A., Budinger, G. S., D'Aquila, R. T., Hope, T. J., Kato, A., Le Poole, I. C., Lesniak, M. S., Luo, X., Misharin, A., Perlman, H. R., Schleimer, R. P., Singer, B., Swaminathan, S., Sznajder, J. I., Tetreault, M., Thorp, E. B. & Wunderink, R. G.

Office of the Director, National Institutes of Health

8/8/19 → 8/7/20

Project: Research project

S 6
Lasers
Translational Medical Research
Health
Therapeutics

Understanding skin rash secondary to checkpoint inhibitor immunotherapy-ATF

Le Poole, I. C.

Melanoma Research Foundation

2/1/19 → 2/1/20

Project: Research project

TOWARDS CHIMERIC ANTIGEN RECEPTOR TRANSGENIC T CELL THERAPY FOR TUBEROUS SCLEROSIS COMPLEX

Le Poole, I. C.

U.S. Army Medical Research and Materiel Command

9/1/18 → 8/31/21

Project: Research project

Antigen Receptors
Tuberous Sclerosis
Cell- and Tissue-Based Therapy
Immunotherapy
Sirolimus

SBIR Phase II - Radikal Therapeutics

Le Poole, I. C.

Radikal Therapeutics Inc, National Institute of Arthritis and Musculoskeletal and Skin Diseases

9/22/17 → 8/31/20

Project: Research project

Vitiligo
Swine
Clinical Trials
Skin
Therapeutics

Separating autoimmunity and anti-tumor immunity

Le Poole, I. C.

National Cancer Institute

8/4/17 → 7/31/20

Project: Research project

Autoimmunity
Immunity
Neoplasms
Dendritic Cells
T-Lymphocytes

Research Output 1992 2019

Molecular properties of gp100-reactive T-cell receptors drive the cytokine profile and antitumor efficacy of transgenic host T cells

Eby, J. M., Smith, A. R., Riley, T. P., Cosgrove, C., Ankney, C. M., Henning, S. W., Paulos, C. M., Garrett-Mayer, E., Luiten, R. M., Nishimura, M. I., Baker, B. M. & Le Poole, I. C., Jan 1 2019, In : Pigment Cell and Melanoma Research. 32, 1, p. 68-78 11 p.

Research output: Contribution to journal › Article

T-cells
T-Cell Antigen Receptor
T-Lymphocytes
Tumors
Interleukin-17
4 Citations (Scopus)

The convergence theory for vitiligo: A reappraisal

Kundu, R. V., Mhlaba, J. M., Rangel, S. M. & Le Poole, I. C., Jun 1 2019, In : Experimental Dermatology. 28, 6, p. 647-655 9 p.

Research output: Contribution to journal › Review article

Open Access
Vitiligo
T-cells
Skin
Radiation
Melanocytes

Transgenerational transfer of gene-modified T cells

Cosgrove, C., Dellacecca, E. R., Van Den Berg, J. H., Haanen, J. B., Nishimura, M. I., Le Poole, I. C. & Bergmans, H. E. N., Jul 15 2019, In : Journal for ImmunoTherapy of Cancer. 7, 1, 186.

Research output: Contribution to journal › Article

Open Access
T-Lymphocytes
Genes
Mothers
Antigens
Cell Shape
7 Citations (Scopus)

Clinical and immunologic evaluation of three metastatic melanoma patients treated with autologous melanoma-reactive TCR-transduced T cells

Moore, T., Wagner, C. R., Scurti, G. M., Hutchens, K. A., Godellas, C., Clark, A. L., Kolawole, E. M., Hellman, L. M., Singh, N. K., Huyke, F. A., Wang, S. Y., Calabrese, K. M., Embree, H. D., Orentas, R., Shirai, K., Dellacecca, E., Garrett-Mayer, E., Li, M., Eby, J. M., Stiff, P. J. & 6 others, Evavold, B. D., Baker, B. M., Le Poole, I. C., Dropulic, B., Clark, J. I. & Nishimura, M. I., Feb 1 2018, In : Cancer Immunology, Immunotherapy. 67, 2, p. 311-325 15 p.

Research output: Contribution to journal › Article

Melanoma
T-Lymphocytes
Interleukin-2
Vitiligo
Monophenol Monooxygenase

Correction to: Clinical and immunologic evaluation of three metastatic melanoma patients treated with autologous melanoma-reactive TCR-transduced T cells (Cancer Immunology, Immunotherapy, (2018), 67, 2, (311-325), 10.1007/s00262-017-2073-0)

Moore, T., Wagner, C. R., Scurti, G. M., Hutchens, K. A., Godellas, C., Clark, A. L., Kolawole, E. M., Hellman, L. M., Singh, N. K., Huyke, F. A., Wang, S. Y., Calabrese, K. M., Embree, H. D., Orentas, R., Shirai, K., Dellacecca, E., Garrett-Mayer, E., Li, M., Eby, J. M., Stiff, P. J. & 6 others, Evavold, B. D., Baker, B. M., Le Poole, I. C., Dropulic, B., Clark, J. I. & Nishimura, M. I., Feb 1 2018, In : Cancer Immunology, Immunotherapy. 67, 2, 1 p.

Research output: Contribution to journal › Comment/debate

HLA-A2 Antigen
Monophenol Monooxygenase
Allergy and Immunology
Immunotherapy
Interleukin-2