• 8904 Citations
1983 …2024
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Personal profile

Research Interests

Asthma, Chronic obstructive pulmonary disease (COPD), Interstitial lung disease

Certifications and Licenses

Pulmonary Disease
Internal Medicine

Training Experience

1980Internship, Rambam Medical Center, Israel
1982Residency, Rambam Medical Center, Israel
1986Fellowship, University of Chicago Hospitals

Education/Academic qualification

MD, Israel Institute of Technology

… → 1978

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Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 1992 2024

Hypercapnia
Lung
Chronic Obstructive Pulmonary Disease
Lung Diseases
Smooth Muscle
Acute Lung Injury
Ubiquitination
Lung Injury
Influenza A virus
Human Influenza
Lung
Human Influenza
Influenza A virus
Alveolar Macrophages
Lung Injury
Lung
Human Influenza
Influenza A virus
Alveolar Macrophages
Lung Injury

Research Output 1983 2019

Erratum: Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis (Cell Metabolism (2019) 29(2) (335–347.e5), (S1550413118305862) (10.1016/j.cmet.2018.09.019))

Soberanes, S., Misharin, A., Jairaman, A., Morales-Nebreda, L., McQuattie-Pimentel, A. C., Cho, T., Hamanaka, R. B., Meliton, A. Y., Reyfman, P. A., Walter, J. M., Chen, C. I., Chi, M., Chiu, S., Gonzalez-Gonzalez, F. J., Antalek, M., Abdala-Valencia, H., Chiarella, S. E., Sun, K. A., Woods, P. S., Ghio, A. J. & 12 othersJain, M., Perlman, H. R., Ridge, K. M., Morimoto, R. I., Sznajder, J. I., Balch, W. E., Bhorade, S. M., Bharat, A., Prakriya, M., Chandel, N., Mutlu, G. M. & Budinger, G. R. S., Feb 5 2019, In : Cell Metabolism. 29, 2, 1 p.

Research output: Contribution to journalComment/debate

Metformin
Air Pollution
Electron Transport
Names
Publications

Influenza A virus infection induces muscle wasting via IL-6 regulation of the E3 ubiquitin ligase atrogin-1

Radigan, K. A., Nicholson, T. T., Welch, L. C., Chi, M., Amarelle, L., Angulo, M., Shigemura, M., Shigemura, A., Runyan, C. E., Morales-Nebreda, L., Perlman, H. R., Ceco, E., Lecuona, E., Dada, L., Misharin, A., Mutlu, G. M., Sznajder, J. I. & Budinger, GR. S., Jan 15 2019, In : Journal of Immunology. 202, 2, p. 484-493 10 p.

Research output: Contribution to journalArticle

Ubiquitin-Protein Ligases
Influenza A virus
Virus Diseases
Interleukin-6
Human Influenza
4 Citations (Scopus)

Future research directions in pneumonia

Dela Cruz, C. S., Wunderink, R. G., Christiani, D. C., Cormier, S. A., Crothers, K., Doerschuk, C. M., Evans, S. E., Goldstein, D. R., Khatri, P., Kobzik, L., Kolls, J. K., Levy, B. D., Metersky, M. L., Niederman, M. S., Nusrat, R., Orihuela, C. J., Peyrani, P., Prince, A. S., Ramírez, J. A., Ridge, K. M. & 9 othersSethi, S., Suratt, B. T., Sznajder, J. I., Tsalik, E. L., Walkey, A. J., Yende, S., Aggarwal, N. R., Caler, E. V. & Mizgerd, J. P., Jul 15 2018, In : American journal of respiratory and critical care medicine. 198, 2, p. 256-263 8 p.

Research output: Contribution to journalArticle

Pneumonia
Lung
Direction compound
National Heart, Lung, and Blood Institute (U.S.)
Adult Respiratory Distress Syndrome
1 Citation (Scopus)
Hypercapnia
Nucleosomes
Lipid Metabolism
Epithelial Cells
Carbon Monoxide
1 Citation (Scopus)

Hypercapnia increases airway smooth muscle contractility via caspase-7-mediated miR-133a-RhoA signaling

Shigemura, M., Lecuona, E., Angulo, M., Homma, T., Rodríguez, D. A., Gonzalez-Gonzalez, F. J., Welch, L. C., Amarelle, L., Kim, S., Kaminski, N., Budinger, GR. S., Solway, J. & Sznajder, J. I., Sep 5 2018, In : Science Translational Medicine. 10, 457, aat1662.

Research output: Contribution to journalArticle

Caspase 7
Hypercapnia
MicroRNAs
Smooth Muscle
Chronic Obstructive Pulmonary Disease