Jaehyuk Choi

  • 986 Citations
20032022
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Research Output 2003 2019

  • 986 Citations
  • 30 Article
  • 8 Review article
  • 3 Comment/debate
  • 1 Letter
2019
3 Citations (Scopus)

Celastrol-loaded PEG-: B -PPS nanocarriers as an anti-inflammatory treatment for atherosclerosis

Allen, S. D., Liu, Y. G., Kim, T., Bobbala, S., Yi, S., Zhang, X., Choi, J. & Scott, E. A., Feb 1 2019, In : Biomaterials Science. 7, 2, p. 657-668 12 p.

Research output: Contribution to journalArticle

Micelles
Polyethylene glycols
Anti-Inflammatory Agents
Polypropylenes
Polydispersity
3 Citations (Scopus)

The coincidence between increasing age, immunosuppression, and the incidence of patients with glioblastoma

Ladomersky, E., Scholtens, D. M., Kocherginsky, M., Hibler, E. A., Bartom, E. T., Otto-Meyer, S., Zhai, L., Lauing, K. L., Choi, J., Sosman, J. A., Wu, J. D., Zhang, B., Lukas, R. V. & Wainwright, D. A., Jan 1 2019, In : Frontiers in Pharmacology. 10, MAR, 200.

Research output: Contribution to journalArticle

Open Access
Glioblastoma
Immunosuppression
Immunotherapy
Central Nervous System
Incidence
2018
15 Citations (Scopus)

A dormant TIL phenotype defines non-small cell lung carcinomas sensitive to immune checkpoint blockers

Gettinger, S. N., Choi, J., Mani, N., Sanmamed, M. F., Datar, I., Sowell, R., Du, V. Y., Kaftan, E., Goldberg, S., Dong, W., Zelterman, D., Politi, K., Kavathas, P., Kaech, S., Yu, X., Zhao, H., Schlessinger, J., Lifton, R., Rimm, D. L., Chen, L. & 2 others, Herbst, R. S. & Schalper, K. A., Dec 1 2018, In : Nature communications. 9, 1, 3196.

Research output: Contribution to journalArticle

Open Access
Tumor-Infiltrating Lymphocytes
phenotype
Lymphocytes
lymphocytes
Non-Small Cell Lung Carcinoma
1 Citation (Scopus)

Are MicroRNAs Key to Developing Biomarkers for Cutaneous T-Cell Lymphoma?

Martinez-Escala, M. E. & Choi, J., Sep 1 2018, In : Journal of Investigative Dermatology. 138, 9, p. 1906-1908 3 p.

Research output: Contribution to journalComment/debate

Cutaneous T-Cell Lymphoma
T-cells
Biomarkers
MicroRNAs
Hematologic Neoplasms
14 Citations (Scopus)

Are there multiple cells of origin of Merkel cell carcinoma?

Sunshine, J. C., Jahchan, N. S., Sage, J. & Choi, J., Mar 1 2018, In : Oncogene. 37, 11, p. 1409-1416 8 p.

Research output: Contribution to journalReview article

Merkel cell polyomavirus
Merkel Cell Carcinoma
Keratinocytes
Neoplasms
Fibroblasts
39 Citations (Scopus)
Non-Small Cell Lung Carcinoma
Immunotherapy
Melanoma
Clinical Trials
CTLA-4 Antigen
10 Citations (Scopus)

Distinct Patterns of Acral Melanoma Based on Site and Relative Sun Exposure

Haugh, A. M., Zhang, B., Quan, V. L., Garfield, E. M., Bubley, J. A., Kudalkar, E., Verzi, A. E., Walton, K., VandenBoom, T., Merkel, E. A., Lee, C. Y., Tan, T., Isales, M. C., Kong, B. Y., Wenzel, A. T., Bunick, C. G., Choi, J., Sosman, J. A. & Gerami, P., Feb 1 2018, In : Journal of Investigative Dermatology. 138, 2, p. 384-393 10 p.

Research output: Contribution to journalArticle

Cyclin D1
Solar System
Aberrations
Sun
Melanoma
6 Citations (Scopus)

Genomic Analyses Identify Recurrent Alterations in Immune Evasion Genes in Diffuse Large B-Cell Lymphoma, Leg Type

Zhou, A., Louissaint, A., Wenzel, A., Yang, J., Martinez-Escala, M. E., Moy, A. P., Morgan, E. A., Paxton, C. N., Hong, B., Andersen, E. F., Guitart, J., Behdad, A., Cerroni, L., Weinstock, D. M. & Choi, J., Nov 1 2018, In : Journal of Investigative Dermatology. 138, 11, p. 2365-2376 12 p.

Research output: Contribution to journalArticle

Immune Evasion
Lymphoma, Large B-Cell, Diffuse
Neurology
Leg
Genes
3 Citations (Scopus)

Hemophagocytic lymphohistiocytosis in cutaneous T-cell lymphoma

Lee, D. E., Martinez-Escala, M. E., Serrano, L. M., Zhou, X. A., Kaplan, J. B., Pro, B., Choi, J. & Guitart, J., Jul 1 2018, In : JAMA Dermatology. 154, 7, p. 828-831 4 p.

Research output: Contribution to journalArticle

Hemophagocytic Lymphohistiocytosis
Cutaneous T-Cell Lymphoma
Subcutaneous Tissue
Stem Cell Transplantation
Therapeutics
10 Citations (Scopus)

Merkel cell carcinoma patients presenting without a primary lesion have elevated markers of immunity, higher tumor mutation burden, and improved survival

Vandeven, N., Lewis, C. W., Makarov, V., Riaz, N., Paulson, K. G., Hippe, D., Bestick, A., Doumani, R., Marx, T., Takagishi, S., Chan, T. A., Choi, J. & Nghiem, P., Feb 15 2018, In : Clinical Cancer Research. 24, 4, p. 963-971 9 p.

Research output: Contribution to journalArticle

Merkel Cell Carcinoma
Tumor Burden
Immunity
Mutation
Survival
9 Citations (Scopus)

Progression of undiagnosed cutaneous lymphoma after anti–tumor necrosis factor-alpha therapy

Martinez-Escala, M. E., Posligua, A. L., Wickless, H., Rutherford, A., Sable, K. A., Rubio-Gonzalez, B., Zhou, A., Kaplan, J. B., Pro, B., Choi, J., Querfeld, C., Rosen, S. T. & Guitart, J., Jun 1 2018, In : Journal of the American Academy of Dermatology. 78, 6, p. 1068-1076 9 p.

Research output: Contribution to journalArticle

Lymphoma
Necrosis
Skin
Cutaneous T-Cell Lymphoma
B-Cell Lymphoma
2017
10 Citations (Scopus)

CD8+ mycosis fungoides: A low-grade lymphoproliferative disorder

Martinez-Escala, M. E., Kantor, R. W., Cices, A., Zhou, A., Kaplan, J. B., Pro, B., Choi, J. & Guitart, J., Sep 1 2017, In : Journal of the American Academy of Dermatology. 77, 3, p. 489-496 8 p.

Research output: Contribution to journalArticle

Mycosis Fungoides
Lymphoproliferative Disorders
Surface Antigens
Observation
Pediatrics
3 Citations (Scopus)

Challenges and future of biomarker tests in the era of precision oncology: Can we rely on immunohistochemistry (IHC) or fluorescence in situ hybridization (FISH) to select the optimal patients for matched therapy?

Chae, Y. K., Arya, A., Chiec, L., Shah, H., Rosenberg, A., Patel, S., Raparia, K., Choi, J., Wainwright, D. A., Villaflor, V., Cristofanilli, M. & Giles, F., Jan 1 2017, In : Oncotarget. 8, 59, p. 100863-100898 36 p.

Research output: Contribution to journalReview article

Fluorescence In Situ Hybridization
Biomarkers
Immunohistochemistry
Molecular Targeted Therapy
Proto-Oncogene Proteins c-met
3 Citations (Scopus)

FISH Panel for Leukemic CTCL

Weed, J., Gibson, J., Lewis, J., Carlson, K., Foss, F., Choi, J., Li, P. & Girardi, M., Mar 1 2017, In : Journal of Investigative Dermatology. 137, 3, p. 751-753 3 p.

Research output: Contribution to journalArticle

Neoplasm DNA
Cutaneous T-Cell Lymphoma
Skin Neoplasms
Tumor Biomarkers
Mutation
2 Citations (Scopus)

Functional analysis of acquired CD28 mutations identified in cutaneous T cell lymphoma

Gmyrek, G. B., Pingel, J., Choi, J. & Green, J. M., Sep 1 2017, In : Cellular Immunology. 319, p. 28-34 7 p.

Research output: Contribution to journalArticle

Cutaneous T-Cell Lymphoma
T-Lymphocytes
Mutation
Cell Proliferation
Neoplasms
21 Citations (Scopus)

Genomic analysis of 220 CTCLs identifies a novel recurrent gain-of-function alteration in RLTPR (p.Q575E)

Park, J., Yang, J., Wenzel, A. T., Ramachandran, A., Lee, W. J., Daniels, J. C., Kim, J., Martinez-Escala, E., Amankulor, N., Pro, B., Guitart, J., Mendillo, M. L., Savas, J. N., Boggon, T. J. & Choi, J., Sep 21 2017, In : Blood. 130, 12, p. 1430-1440 11 p.

Research output: Contribution to journalArticle

Cutaneous T-Cell Lymphoma
T-cells
NF-kappa B
T-Cell Antigen Receptor
T-Lymphocytes
4 Citations (Scopus)

Photopheresis: Advances and Use in Systemic Sclerosis

Zhou, A. & Choi, J., Jun 1 2017, In : Current rheumatology reports. 19, 6, 31.

Research output: Contribution to journalReview article

Photopheresis
Systemic Scleroderma
Photosensitizing Agents
Graft Rejection
Graft vs Host Disease
15 Citations (Scopus)

Treatment of Hypereosinophilic Syndrome with Cutaneous Involvement with the JAK Inhibitors Tofacitinib and Ruxolitinib

King, B., Lee, A. I. & Choi, J., Apr 1 2017, In : Journal of Investigative Dermatology. 137, 4, p. 951-954 4 p.

Research output: Contribution to journalArticle

Piperidines
Pyrazoles
Hypereosinophilic Syndrome
Pyrimidines
Pyrroles
2016
1 Citation (Scopus)

A discordant cutaneous eruption in a neonatal twin

Damsky, W. E., Craiglow, B. G. & Choi, J., Apr 1 2016, In : JAMA Dermatology. 152, 4, p. 463-464 2 p.

Research output: Contribution to journalComment/debate

Cutaneous Candidiasis
Erythema
Newborn Infant
Skin
16 Citations (Scopus)

Cutaneous T-cell lymphoma (CTCL): Current practices in blood assessment and the utility of T-cell receptor (TCR)-Vβ chain restriction

Gibson, J. F., Huang, J., Liu, K. J., Carlson, K. R., Foss, F., Choi, J., Edelson, R., Hussong, J. W., Mohl, R., Hill, S. & Girardi, M., May 1 2016, In : Journal of the American Academy of Dermatology. 74, 5, p. 870-877 8 p.

Research output: Contribution to journalArticle

Cutaneous T-Cell Lymphoma
T-Cell Antigen Receptor
Lymphoma
Skin
CD4-CD8 Ratio
5 Citations (Scopus)

Defining the polyposis/colorectal cancer phenotype associated with the Ashkenazi GREM1 duplication: Counselling and management recommendations

ZIAI, JAMES., MATLOFF, ELLEN., CHOI, JAEHYUK., KOMBO, NINANI., MATERIN, MIGUEL. & BALE, ALLEN. E., Mar 7 2016, In : Genetics Research. 98, e5.

Research output: Contribution to journalArticle

Colonic Neoplasms
Counseling
Colorectal Neoplasms
Phenotype
Mutation
21 Citations (Scopus)

Genetics of Cutaneous T Cell Lymphoma: From Bench to Bedside

Damsky, W. E. & Choi, J., Jul 1 2016, In : Current Treatment Options in Oncology. 17, 7, 33.

Research output: Contribution to journalReview article

Cutaneous T-Cell Lymphoma
T-Lymphocytes
Neoplasms
Precision Medicine
Skin
46 Citations (Scopus)

Genomic characterization of sarcomatoid transformation in clear cell renal cell carcinoma

Bi, M., Zhao, S., Said, J. W., Merino, M. J., Adeniran, A. J., Xie, Z., Nawaf, C. B., Choi, J., Belldegrun, A. S., Pantuck, A. J., Kluger, H. M., Bilgövar, K., Lifton, R. P. & Shuch, B., Feb 23 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 8, p. 2170-2175 6 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Neoplasms
Nucleotides
Loss of Heterozygosity
Mutation
17 Citations (Scopus)

Identification of a gain-of-function stat3 mutation (p.Y640F) in lymphocytic variant hypereosinophilic syndrome

Walker, S., Wang, C., Walradt, T., Hong, B. S., Tanner, J. R., Levinsohn, J. L., Goh, G., Subtil, A., Lessin, S. R., Heymann, W. R., Vonderheid, E. C., King, B. A., Lifton, R. P. & Choi, J., Feb 18 2016, In : Blood. 127, 7, p. 948-951 4 p.

Research output: Contribution to journalLetter

36 Citations (Scopus)

IDH mutant gliomas escape natural killer cell immune surveillance by downregulation of NKG2D ligand expression

Zhang, X., Rao, A., Sette, P., Deibert, C., Pomerantz, A., Kim, W. J., Kohanbash, G., Chang, Y., Park, Y., Engh, J., Choi, J., Chan, T., Okada, H., Lotze, M., Grandi, P. & Amankulor, N., Oct 1 2016, In : Neuro-Oncology. 18, 10, p. 1402-1412 11 p.

Research output: Contribution to journalArticle

Glioma
Natural Killer Cells
Down-Regulation
Ligands
decitabine
119 Citations (Scopus)

Mutational landscape of MCPyV-positive and MCPyV-negative merkel cell carcinomas with implications for immunotherapy

Goh, G., Walradt, T., Markarov, V., Blom, A., Riaz, N., Doumani, R., Stafstrom, K., Moshiri, A., Yelistratova, L., Levinsohn, J., Chan, T. A., Nghiem, P., Lifton, R. P. & Choi, J., Jan 1 2016, In : Oncotarget. 7, 3, p. 3403-3415 13 p.

Research output: Contribution to journalArticle

Merkel cell polyomavirus
Merkel Cell Carcinoma
Immunotherapy
Mutation
Exome
10 Citations (Scopus)

Nonoverlapping Clinical and Mutational Patterns in Melanomas from the Female Genital Tract and Atypical Genital Nevi

Yélamos, O., Merkel, E. A., Sholl, L. M., Zhang, B., Amin, S. M., Lee, C. Y., Guitart, G. E., Yang, J., Wenzel, A. T., Bunick, C. G., Yazdan, P., Choi, J. & Gerami, P., Sep 1 2016, In : Journal of Investigative Dermatology. 136, 9, p. 1858-1865 8 p.

Research output: Contribution to journalArticle

Nevus
Aberrations
Melanoma
Tumors
Genes
29 Citations (Scopus)

Telomere Replication Stress Induced by POT1 Inactivation Accelerates Tumorigenesis

Pinzaru, A. M., Hom, R. A., Beal, A., Phillips, A. F., Ni, E., Cardozo, T., Nair, N., Choi, J., Wuttke, D. S., Sfeir, A. & Denchi, E. L., Jun 7 2016, In : Cell reports. 15, 10, p. 2170-2184 15 p.

Research output: Contribution to journalArticle

T-cells
Telomere
Carcinogenesis
Lymphoid Progenitor Cells
Elongation
2015
6 Citations (Scopus)

A primary melanoma and its asynchronous metastasis highlight the role of BRAF, CDKN2A, and TERT

Hosler, G. A., Davoli, T., Mender, I., Litzner, B., Choi, J., Kapur, P., Shay, J. W. & Wang, R. C., Jan 1 2015, In : Journal of Cutaneous Pathology. 42, 2, p. 108-117 10 p.

Research output: Contribution to journalArticle

Melanoma
Neoplasm Metastasis
Mutation
Atlases
Genome
158 Citations (Scopus)

Genomic landscape of cutaneous T cell lymphoma

Choi, J., Goh, G., Walradt, T., Hong, B. S., Bunick, C. G., Chen, K., Bjornson, R. D., Maman, Y., Wang, T., Tordoff, J., Carlson, K., Overton, J. D., Liu, K. J., Lewis, J. M., Devine, L., Barbarotta, L., Foss, F. M., Subtil, A., Vonderheid, E. C., Edelson, R. L. & 4 others, Schatz, D. G., Boggon, T. J., Girardi, M. & Lifton, R. P., Aug 27 2015, In : Nature Genetics. 47, 9, p. 1011-1019 9 p.

Research output: Contribution to journalArticle

Cutaneous T-Cell Lymphoma
Exome
RNA Sequence Analysis
T-Lymphocytes
Mutation
2014
14 Citations (Scopus)

Activation of GILZ gene by photoactivated 8-methoxypsoralen: Potential role of immunoregulatory dendritic cells in extracorporeal photochemotherapy

Futterleib, J. S., Feng, H., Tigelaar, R. E., Choi, J. & Edelson, R. L., Jan 1 2014, In : Transfusion and Apheresis Science. 50, 3, p. 379-387 9 p.

Research output: Contribution to journalArticle

Photopheresis
Methoxsalen
Leucine Zippers
Dendritic Cells
Glucocorticoids
30 Citations (Scopus)

Identification of PLX4032-resistance mechanisms and implications for novel RAF inhibitors

Choi, J., Landrette, S. F., Wang, T., Evans, P., Bacchiocchi, A., Bjornson, R., Cheng, E., Stiegler, A. L., Gathiaka, S., Acevedo, O., Boggon, T. J., Krauthammer, M., Halaban, R. & Xu, T., Mar 1 2014, In : Pigment Cell and Melanoma Research. 27, 2, p. 253-262 10 p.

Research output: Contribution to journalArticle

Mutation
Melanoma
Mutagenesis
Aberrations
Exome
2 Citations (Scopus)

Rapidly enlarging nodular plaque on the leg

Little, A. J., Subtil, A. & Choi, J., Jan 1 2014, In : JAMA Dermatology. 150, 10, p. 1107-1108 2 p.

Research output: Contribution to journalComment/debate

Facial Neoplasms
Extranodal NK-T-Cell Lymphoma
Skin Neoplasms
L-Lactate Dehydrogenase
Leg
2011
21 Citations (Scopus)

Pityriasis rubra pilaris: the clinical context of acantholysis and other histologic features

Ko, C. J., Milstone, L. M., Choi, J. & Mcniff, J. M., Dec 1 2011, In : International Journal of Dermatology. 50, 12, p. 1480-1485 6 p.

Research output: Contribution to journalArticle

Pityriasis Rubra Pilaris
Acantholysis
Exfoliative Dermatitis
Psoriasis
Benign Familial Pemphigus
2008
13 Citations (Scopus)

Carpal tunnel syndrome associated with the use of aromatase inhibitors in breast cancer

Nishihori, T., Choi, J., DiGiovanna, M. P., Thomson, J. G., Kohler, P. C., McGurn, J. & Chung, G. G., Jan 1 2008, In : Clinical Breast Cancer. 8, 4, p. 362-365 4 p.

Research output: Contribution to journalArticle

Aromatase Inhibitors
Carpal Tunnel Syndrome
Breast Neoplasms
Nerve Compression Syndromes
Median Nerve
28 Citations (Scopus)

Cutaneous T-cell Lymphoma

Lansigan, F., Choi, J. & Foss, F. M., Oct 1 2008, In : Hematology/Oncology Clinics of North America. 22, 5, p. 979-996 18 p.

Research output: Contribution to journalReview article

Cutaneous T-Cell Lymphoma
Mycosis Fungoides
Lymphoproliferative Disorders
T-Lymphocytes
Skin
2007
2 Citations (Scopus)

Cutaneous T-cell lymphoma: Biologic targets for therapy

Choi, J. & Foss, F., Dec 1 2007, In : Current Hematologic Malignancy Reports. 2, 4, p. 272-277 6 p.

Research output: Contribution to journalReview article

Cutaneous T-Cell Lymphoma
Biological Therapy
Immunologic Monitoring
Christianity
Neoplasms
2006
4 Citations (Scopus)

Efficacy of low dose clofarabine in refractory precursor T- acute lymphoblastic leukemia

Choi, J. & Foss, F., Dec 1 2006, In : Yale Journal of Biology and Medicine. 79, 3-4, p. 169-172 4 p.

Research output: Contribution to journalArticle

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Refractory materials
T-Cell Leukemia
Transplants
Pediatrics
2005
19 Citations (Scopus)

Endothelial cells promote human immunodeficiency virus replication in nondividing memory T cells via Nef-, Vpr-, and T-cell receptor-dependent activation of NFAT

Choi, J., Walker, J., Talbert-Slagle, K., Wright, P., Pober, J. S. & Alexander, L., Sep 1 2005, In : Journal of virology. 79, 17, p. 11194-11204 11 p.

Research output: Contribution to journalArticle

Human immunodeficiency virus
Virus Replication
virus replication
T-Cell Antigen Receptor
endothelial cells
19 Citations (Scopus)

Human endothelial cells enhance human immunodeficiency virus type 1 replication in CD4+ T cells in a Nef-dependent manner in vitro and in vivo

Choi, J., Walker, J., Boichuk, S., Kirkiles-Smith, N., Torpey, N., Pober, J. S. & Alexander, L., Jan 1 2005, In : Journal of virology. 79, 1, p. 264-276 13 p.

Research output: Contribution to journalArticle

Virus Replication
Human immunodeficiency virus 1
endothelial cells
HIV-1
Endothelial Cells
2004
149 Citations (Scopus)

T lymphocyte-endothelial cell interactions

Choi, J., Enis, D. R., Koh, K. P., Shiao, S. L. & Pober, J. S., Jun 7 2004, In : Annual Review of Immunology. 22, p. 683-709 27 p.

Research output: Contribution to journalReview article

Cell Communication
Endothelial Cells
T-Lymphocytes
Antigen Presentation
HLA Antigens
2003
50 Citations (Scopus)

Inhibition of phosphatidylinositol 3-kinase sensitizes vascular endothelial cells to cytokine-initiated cathepsin-dependent apoptosis

Madge, L. A., Li, J. H., Choi, J. & Pober, J. S., Jun 6 2003, In : Journal of Biological Chemistry. 278, 23, p. 21295-21306 12 p.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Cathepsins
Endothelial cells
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
Cycloheximide