Jaime N Guzman-Lucero

  • 2620 Citations
20032021
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Personal profile

Training Experience

2009Postdoctoral Fellowship, Northwestern University Feinberg School of Medicine

Education/Academic qualification

PhD, Universidad Nacional Autonoma de Mexico

… → 2004

MD, Universidad Nacional Autonoma de Mexico

… → 1998

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Parkinson Disease Medicine & Life Sciences
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Grants 2007 2021

Parkinson Disease
Levodopa
Dopaminergic Neurons
Dyskinesias
Substantia Nigra
Subthalamic Nucleus
Nerve Degeneration
Dopaminergic Neurons
Parkinson Disease
National Institute of Neurological Disorders and Stroke
Levodopa
Parkinson Disease
Dyskinesias
Dopaminergic Neurons
Muscarinic M4 Receptors

Research Output 2003 2018

  • 2620 Citations
  • 18 Article
  • 4 Review article
  • 2 Chapter
  • 1 Comment/debate
6 Citations

Systemic isradipine treatment diminishes calcium-dependent mitochondrial oxidant stress

Guzman-Lucero, J. N., Ilijic, E., Yang, B., Sanchez-Padilla, J., Wokosin, D. L., Galtieri, D., Kondapalli, J., Schumacker, P. T. & Surmeier Jr, D. J., Jun 1 2018, In : Journal of Clinical Investigation. 128, 6, p. 2266-2280 15 p.

Research output: Contribution to journalArticle

Isradipine
Dopaminergic Neurons
Oxidants
Calcium
Mitochondrial Degradation
4 Citations

Cryopreservation Maintains Functionality of Human iPSC Dopamine Neurons and Rescues Parkinsonian Phenotypes In Vivo

Wakeman, D. R., Hiller, B. M., Marmion, D. J., McMahon, C. W., Corbett, G. T., Mangan, K. P., Ma, J., Little, L. E., Xie, Z., Perez-Rosello, T., Guzman-Lucero, J. N., Surmeier Jr, D. J. & Kordower, J. H., Jul 11 2017, In : Stem Cell Reports. 9, 1, p. 149-161 13 p.

Research output: Contribution to journalArticle

Dopaminergic Neurons
Cryopreservation
Neurons
Dopamine
Mesencephalon
47 Citations

Mitochondrial oxidant stress in locus coeruleus is regulated by activity and nitric oxide synthase

Sanchez-Padilla, J., Guzman-Lucero, J. N., Ilijic, E., Kondapalli, J., Galtieri, D. J., Yang, B., Schieber, S., Oertel, W., Wokosin, D. L., Schumacker, P. T. & Surmeier Jr, D. J., Jan 1 2014, In : Nature Neuroscience. 17, 6, p. 832-840 9 p.

Research output: Contribution to journalArticle

Locus Coeruleus
Oxidants
Nitric Oxide Synthase
Neurons
Parkinson Disease
86 Citations

Calcium entry and α-synuclein inclusions elevate dendritic mitochondrial oxidant stress in dopaminergic neurons

Dryanovski, D. I., Guzman-Lucero, J. N., Xie, Z., Galteri, D. J., Volpicelli-Daley, L. A., Lee, V. M. Y., Miller, R. J., Schumacker, P. T. & Surmeier Jr, D. J., Jun 17 2013, In : Journal of Neuroscience. 33, 24, p. 10154-10164 11 p.

Research output: Contribution to journalArticle

alpha-Synuclein
Dopaminergic Neurons
Oxidants
Dendrites
Calcium