Jaime N Guzman-Lucero

  • 3030 Citations
20032021

Research output per year

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Research Output

  • 3030 Citations
  • 19 Article
  • 4 Review article
  • 2 Chapter
  • 1 Comment/debate
2019

Mutant huntingtin enhances activation of dendritic Kv4 K+ channels in striatal spiny projection neurons

Carrillo-Reid, L., Day, M., Xie, Z., Melendez, A. E., Kondapalli, J., Plotkin, J. L., Wokosin, D. L., Chen, Y., Kress, G. J., Kaplitt, M., Ilijic, E., Guzman, J. N., Chan, C. S. & Surmeier, D. J., Apr 2019, In : eLife. 8, e40818.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018

Systemic isradipine treatment diminishes calcium-dependent mitochondrial oxidant stress

Guzman, J. N., Ilijic, E., Yang, B., Sanchez-Padilla, J., Wokosin, D., Galtieri, D., Kondapalli, J., Schumacker, P. T. & Surmeier, D. J., Jun 1 2018, In : Journal of Clinical Investigation. 128, 6, p. 2266-2280 15 p.

Research output: Contribution to journalArticle

25 Scopus citations
2017

Cryopreservation Maintains Functionality of Human iPSC Dopamine Neurons and Rescues Parkinsonian Phenotypes In Vivo

Wakeman, D. R., Hiller, B. M., Marmion, D. J., McMahon, C. W., Corbett, G. T., Mangan, K. P., Ma, J., Little, L. E., Xie, Z., Perez-Rosello, T., Guzman, J. N., Surmeier, D. J. & Kordower, J. H., Jul 11 2017, In : Stem cell reports. 9, 1, p. 149-161 13 p.

Research output: Contribution to journalArticle

22 Scopus citations
2015

Corrigendum: Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1(Nature (2010) 468 (696-700) 10.1038/nature09536)

Guzman, J. N., Sanchez-Padilla, J., Wokosin, D., Kondapalli, J., Ilijic, E., Schumacker, P. T. & Surmeier, D. J., May 20 2015, In : Nature. 521, 7552, 1 p.

Research output: Contribution to journalComment/debate

2 Scopus citations
2014

Mitochondrial oxidant stress in locus coeruleus is regulated by activity and nitric oxide synthase

Sanchez-Padilla, J., Guzman, J. N., Ilijic, E., Kondapalli, J., Galtieri, D. J., Yang, B., Schieber, S., Oertel, W., Wokosin, D., Schumacker, P. T. & Surmeier, D. J., Jun 2014, In : Nature Neuroscience. 17, 6, p. 832-840 9 p.

Research output: Contribution to journalArticle

64 Scopus citations
2013

Calcium entry and α-synuclein inclusions elevate dendritic mitochondrial oxidant stress in dopaminergic neurons

Dryanovski, D. I., Guzman, J. N., Xie, Z., Galteri, D. J., Volpicelli-Daley, L. A., Lee, V. M. Y., Miller, R. J., Schumacker, P. T. & James Surmeier, D., Jun 17 2013, In : Journal of Neuroscience. 33, 24, p. 10154-10164 11 p.

Research output: Contribution to journalArticle

108 Scopus citations
2012

Calcium entry induces mitochondrial oxidant stress in vagal neurons at risk in Parkinson's disease

Goldberg, J. A., Guzman, J. N., Estep, C. M., Ilijic, E., Kondapalli, J., Sanchez-Padilla, J. & Surmeier, D. J., Oct 1 2012, In : Nature Neuroscience. 15, 10, p. 1414-1421 8 p.

Research output: Contribution to journalArticle

85 Scopus citations

Calcium influx, free radicals, and aging: A metabolic burden linked to neuronal loss in Parkinson’s disease

Sanchez-Padilla, J., Guzman-Lucero, J. N. & Surmeier Jr, D. J., Jan 1 2012, Parkinson's Disease, Second Edition. CRC Press, p. 1097-1104 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Physiological phenotype and vulnerability in Parkinson's disease

Surmeier, D. J., Guzman, J. N., Sanchez, J. & Schumacker, P. T., Jul 2012, In : Cold Spring Harbor Perspectives in Medicine. 2, 7, a009290.

Research output: Contribution to journalReview article

68 Scopus citations
2011

HCN channelopathy in external globus pallidus neurons in models of Parkinson's disease

Chan, C. S., Glajch, K. E., Gertler, T. S., Guzman, J. N., Mercer, J. N., Lewis, A. S., Goldberg, A. B., Tkatch, T., Shigemoto, R., Fleming, S. M., Chetkovich, D. M., Osten, P., Kita, H. & Surmeier, D. J., Jan 2011, In : Nature Neuroscience. 14, 1, p. 85-94 10 p.

Research output: Contribution to journalArticle

104 Scopus citations

Optical approaches to studying the basal ganglia

Plotkin, J. L., Guzman, J. N., Schwarz, N., Kress, G., Wokosin, D. L. & Surmeier, D. J., Oct 24 2011, Animal Models of Movement Disorders: Volume I. Lane, E. & Dunnett, S. (eds.). p. 191-220 30 p. (Neuromethods; vol. 61).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations
125 Scopus citations

The origins of oxidant stress in parkinson's disease and therapeutic strategies

Surmeier Jr, D. J., Guzman-Lucero, J. N., Sanchez-Padilla, J. & Goldberg, J. A., Apr 1 2011, In : Antioxidants and Redox Signaling. 14, 7, p. 1289-1301 13 p.

Research output: Contribution to journalReview article

92 Scopus citations
131 Scopus citations
2010

Calcium, cellular aging, and selective neuronal vulnerability in Parkinson's disease

Surmeier, D. J., Guzman, J. N. & Sanchez-Padilla, J., Feb 2010, In : Cell Calcium. 47, 2, p. 175-182 8 p.

Research output: Contribution to journalReview article

128 Scopus citations

Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1

Guzman-Lucero, J. N., Sanchez-Padilla, J., Wokosin, D. L., Kondapalli, J., Ilijic, E., Schumacker, P. T. & Surmeier Jr, D. J., Dec 2 2010, In : Nature. 468, 7324, p. 696-700 5 p.

Research output: Contribution to journalArticle

462 Scopus citations

Thalamic gating of corticostriatal signaling by cholinergic interneurons

Ding, J. B., Guzman-Lucero, J. N., Peterson, J. D., Goldberg, J. A. & Surmeier Jr, D. J., Jul 1 2010, In : Neuron. 67, 2, p. 294-307 14 p.

Research output: Contribution to journalArticle

257 Scopus citations

What causes the death of dopaminergic neurons in Parkinson's disease?

Surmeier Jr, D. J., Guzman-Lucero, J. N., Sanchez-Padilla, J. & Goldberg, J. A., Aug 13 2010, In : Progress in Brain Research. 183, C, p. 59-77 19 p.

Research output: Contribution to journalArticle

71 Scopus citations
2009

Robust pacemaking in substantia nigra dopaminergic neurons

Guzman, J. N., Sánchez-Padilla, J., Chan, C. S. & Surmeier, D. J., Sep 2 2009, In : Journal of Neuroscience. 29, 35, p. 11011-11019 9 p.

Research output: Contribution to journalArticle

209 Scopus citations
2008

Presynaptic modulation by somatostatin in the neostriatum

Lopez-Huerta, V. G., Tecuapetla, F., Guzman, J. N., Bargas, J. & Galarraga, E., Aug 1 2008, In : Neurochemical Research. 33, 8, p. 1452-1458 7 p.

Research output: Contribution to journalArticle

20 Scopus citations
2007

'Rejuvenation' protects neurons in mouse models of Parkinson's disease

Chan, S., Guzman-Lucero, J. N., Ilijic, E., Mercer, J. N., Rick, C., Tkatch, T., Meredith, G. E. & Surmeier Jr, D. J., Jun 28 2007, In : Nature. 447, 7148, p. 1081-1086 6 p.

Research output: Contribution to journalArticle

560 Scopus citations
2006

RGS4-dependent attenuation of M4 autoreceptor function in striatal cholinergic interneurons following dopamine depletion

Ding, J., Guzman, J. N., Tkatch, T., Chen, S., Goldberg, J. A., Ebert, P. J., Levitt, P., Wilson, C. J., Hamm, H. E. & Surmeier, D. J., Jun 16 2006, In : Nature Neuroscience. 9, 6, p. 832-842 11 p.

Research output: Contribution to journalArticle

153 Scopus citations
2005

Cholinergic control of firing pattern and neurotransmission in rat neostriatal projection neurons: Role of CaV2.1 and CaV2.2 Ca2+ channels

Perez-Rosello, T., Figueroa, A., Salgado, H., Vilchis, C., Tecuapetla, F., Guzman, J. N., Galarraga, E. & Bargas, J., May 1 2005, In : Journal of neurophysiology. 93, 5, p. 2507-2519 13 p.

Research output: Contribution to journalArticle

85 Scopus citations

Different inhibitory inputs onto neostriatal projection neurons as revealed by field stimulation

Tecuapetla, F., Carrillo-Reid, L., Guzmán, J. N., Galarraga, E. & Bargas, J., Feb 1 2005, In : Journal of neurophysiology. 93, 2, p. 1119-1126 8 p.

Research output: Contribution to journalArticle

30 Scopus citations
2003

Dopaminergic modulation of axon collaterals interconnecting spiny neurons of the rat striatum

Guzmán, J. N., Hernández, A., Galarraga, E., Tapia, D., Laville, A., Vergara, R., Aceves, J. & Bargas, J., Oct 1 2003, In : Journal of Neuroscience. 23, 26, p. 8931-8940 10 p.

Research output: Contribution to journalArticle

130 Scopus citations

Spontaneous voltage oscillations in striatal projection neurons in a rat corticostriatal slice

Vergara, R., Rick, C., Hernández-López, S., Laville, J. A., Guzman, J. N., Galarraga, E., Surmeier, D. J. & Bargas, J., Nov 15 2003, In : Journal of Physiology. 553, 1, p. 169-182 14 p.

Research output: Contribution to journalArticle

97 Scopus citations