James Mathew

  • 1463 Citations
1987 …2023

Research output per year

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Research Output

2020

Outstanding questions in transplantation: Tolerance

Leventhal, J. R. & Mathew, J. M., Feb 1 2020, In : American Journal of Transplantation. 20, 2, p. 348-354 7 p.

Research output: Contribution to journalReview article

2019

Author Correction: Varying levels of X chromosome coalescence in female somatic cells alters the balance of X-linked dosage compensation and is implicated in female-dominant systemic lupus erythematosus (Scientific Reports, (2019), 9, 1, (8011), 10.1038/s41598-019-44229-9)

Laskowski, A. I., Neems, D. S., Laster, K., Strojny-Okyere, C., Rice, E. L., Konieczna, I. M., Voss, J. H., Mathew, J. M., Leventhal, J. R., Ramsey-Goldman, R., Smith, E. D. & Kosak, S. T., Dec 1 2019, In : Scientific reports. 9, 1, 16145.

Research output: Contribution to journalComment/debate

Open Access

Mechanistic analyses in kidney transplant recipients prospectively randomized to two steroid free regimen-Low dose Tacrolimus with Everolimus versus standard dose Tacrolimus with Mycophenolate Mofetil

Traitanon, O., Mathew, J. M., Shetty, A., Bontha, S. V., Maluf, D. G., El Kassis, Y., Park, S. H., Han, J., Ansari, M. J., Leventhal, J. R., Mas, V. & Gallon, L., May 2019, In : PloS one. 14, 5, e0216300.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Varying levels of X chromosome coalescence in female somatic cells alters the balance of X-linked dosage compensation and is implicated in female-dominant systemic lupus erythematosus

Laskowski, A. I., Neems, D. S., Laster, K., Strojny-Okyere, C., Rice, E. L., Konieczna, I. M., Voss, J. H., Mathew, J. M., Leventhal, J. R., Ramsey-Goldman, R., Smith, E. D. & Kosak, S. T., Dec 1 2019, In : Scientific reports. 9, 1, 8011.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018

A Phase i Clinical Trial with Ex Vivo Expanded Recipient Regulatory T cells in Living Donor Kidney Transplants

Mathew, J. M., H-Voss, J., LeFever, A., Konieczna, I., Stratton, C., He, J., Huang, X., Gallon, L., Skaro, A., Ansari, M. J. & Leventhal, J. R., Dec 1 2018, In : Scientific reports. 8, 1, 7428.

Research output: Contribution to journalArticle

29 Scopus citations

Cellular and functional biomarkers of clinical transplant tolerance

Mathew, J. M., Ansari, M. J., Gallon, L. & Leventhal, J. R., May 2018, In : Human Immunology. 79, 5, p. 322-333 12 p.

Research output: Contribution to journalReview article

2 Scopus citations

Clinical transplant tolerance: Coming of age

Mathew, J. & Leventhal, J. R., May 1 2018, In : Human Immunology. 79, 5, p. 255-257 3 p.

Research output: Contribution to journalEditorial

1 Scopus citations

Generation and Characterization of Alloantigen-Specific Regulatory T Cells for Clinical Transplant Tolerance

Mathew, J. M., Voss, J. H., McEwen, S. T., Konieczna, I., Chakraborty, A., Huang, X., He, J., Gallon, L., Kornbluth, R. S. & Leventhal, J. R., Dec 1 2018, In : Scientific reports. 8, 1, 1136.

Research output: Contribution to journalArticle

10 Scopus citations

Intragraft Molecular Pathways Associated with Tolerance Induction in Renal Transplantation

Gallon, L., Mathew, J. M., Bontha, S. V., Dumur, C. I., Dalal, P., Nadimpalli, L., Maluf, D. G., Shetty, A. A., Ildstad, S. T., Leventhal, J. R. & Mas, V. R., Feb 2018, In : Journal of the American Society of Nephrology. 29, 2, p. 423-433 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Transcriptomic studies in tolerance: Lessons learned and the path forward

Kurian, S. M., Whisenant, T. C., Mathew, J., Miller, J. & Leventhal, J. R., May 2018, In : Human Immunology. 79, 5, p. 395-401 7 p.

Research output: Contribution to journalReview article

2 Scopus citations

Updated follow-up of a tolerance protocol in HLA-identical renal transplant pairs given donor hematopoietic stem cells

Leventhal, J. R., Miller, J., Mathew, J. M., Kurian, S., Tambur, A. R., Friedewald, J., Charrette, J. & Abecassis, M. M., May 2018, In : Human Immunology. 79, 5, p. 277-282 6 p.

Research output: Contribution to journalReview article

4 Scopus citations
2016

Immunoregulatory effects of everolimus on in vitro alloimmune responses

Levitsky, J., Miller, J., Huang, X., Gallon, L., Leventhal, J. R. & Mathew, J. M., Jun 1 2016, In : PloS one. 11, 6, e0156535.

Research output: Contribution to journalArticle

7 Scopus citations

Low incidence of acute rejection in hepatitis B virus positive liver transplant recipients and the impact of hepatitis B immunoglobulin

Veerappan, A., VanWagner, L. B., Mathew, J. M., Huang, X., Miller, J., Lapin, B. & Levitsky, J., Apr 1 2016, In : Human Immunology. 77, 4, p. 367-374 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Nonchimeric HLA-identical renal transplant tolerance: Regulatory immunophenotypic/genomic biomarkers

Leventhal, J. R., Mathew, J. M., Salomon, D. R., Kurian, S. M., Friedewald, J. J., Gallon, L., Konieczna, I., Tambur, A. R., Charette, J., Levitsky, J., Jie, C., Kanwar, Y. S., Abecassis, M. M. & Miller, J., Jan 1 2016, In : American Journal of Transplantation. 16, 1, p. 221-234 14 p.

Research output: Contribution to journalArticle

30 Scopus citations
2015

Cellular and molecular immune profiles in renal transplant recipients after conversion from tacrolimus to sirolimus

Gallon, L., Traitanon, O., Sustento-Reodica, N., Leventhal, J., Ansari, M. J., Gehrau, R. C., Ariyamuthu, V., De Serres, S. A., Alvarado, A., Chhabra, D., Mathew, J. M., Najafian, N. & Mas, V., Apr 8 2015, In : Kidney international. 87, 4, p. 828-838 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

Differential Effects of Calcineurin and Mammalian Target of Rapamycin Inhibitors on Alloreactive Th1, Th17, and Regulatory T Cells

Gallon, L., Traitanon, O., Yu, Y., Shi, B., Leventhal, J. R., Miller, J., Mas, V., L, X. & Mathew, J. M., Sep 1 2015, In : Transplantation. 99, 9, p. 1774-1784 11 p.

Research output: Contribution to journalArticle

29 Scopus citations

Differential effects of tacrolimus versus sirolimus on the proliferation, activation and differentiation of human B cells

Traitanon, O., Mathew, J. M., Monica, G. L., Xu, L., Mas, V. & Gallon, L., Jun 18 2015, In : PloS one. 10, 6, e0129658.

Research output: Contribution to journalArticle

23 Scopus citations

Immune reconstitution/immunocompetence in recipients of kidney plus hematopoietic stem/facilitating cell transplants

Leventhal, J. R., Elliott, M. J., Yolcu, E. S., Bozulic, L. D., Tollerud, D. J., Mathew, J. M., Konieczna, I., Ison, M. G., Galvin, J., Mehta, J., Badder, M. D., Abecassis, M. M. I., Miller, J., Gallon, L. & Ildstad, S. T., Feb 13 2015, In : Transplantation. 99, 2, p. 288-298 11 p.

Research output: Contribution to journalArticle

72 Scopus citations

Role of innate and acquired immune mechanisms in clinical intestinal transplant rejection

Mathew, J. M., Tryphonopoulos, P., Defaria, W., Ruiz, P., Miller, J., Barrett, T. A., Tzakis, A. G. & Kato, T., Jun 6 2015, In : Transplantation. 99, 6, p. 1273-1281 9 p.

Research output: Contribution to journalArticle

6 Scopus citations
2014

Defining the alloreactive T cell repertoire using high-throughput sequencing of mixed lymphocyte reaction culture

Emerson, R. O., Mathew, J. M., Konieczna, I. M., Robins, H. S. & Leventhal, J. R., Nov 3 2014, In : PloS one. 9, 11, e111943.

Research output: Contribution to journalArticle

22 Scopus citations
2013

Genomic biomarkers correlate with HLA-identical renal transplant tolerance

Leventhal, J. R., Mathew, J. M., Salomon, D. R., Kurian, S. M., Suthanthiran, M., Tambur, A., Friedewald, J., Gallon, L., Charette, J., Levitsky, J., Kanwar, Y., Abecassis, M. & Miller, J., Sep 1 2013, In : Journal of the American Society of Nephrology. 24, 9, p. 1376-1385 10 p.

Research output: Contribution to journalArticle

44 Scopus citations

HLA identical non-chimeric and HLA disparate chimeric renal transplant tolerance.

Leventhal, J. R., Mathew, J. M., Ildstad, S., Salomon, D. R., Kurian, S. M., Suthanthiran, M., Tambur, A., Friedewald, J., Gallon, L., Charette, J., Levitsky, J., Kanwar, Y., Abecassis, M. & Miller, J., Jan 1 2013, In : Clinical transplants. p. 145-156 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Inhibitory effects of belatacept on allospecific regulatory T-cell generation in humans

Levitsky, J., Miller, J., Huang, X., Chandrasekaran, D., Chen, L. & Mathew, J. M., Oct 27 2013, In : Transplantation. 96, 8, p. 689-696 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Systemic immunoregulatory and proteogenomic effects of tacrolimus to sirolimus conversion in liver transplant recipients

Levitsky, J., Mathew, J. M., Abecassis, M., Tambur, A., Leventhal, J., Chandrasekaran, D., Herrera, N., Al-Saden, P., Gallon, L., Abdul-Nabi, A., Yang, G. Y., Kurian, S. M., Salomon, D. R. & Miller, J., Jan 1 2013, In : Hepatology. 57, 1, p. 239-248 10 p.

Research output: Contribution to journalArticle

27 Scopus citations
2012

Favorable effects of alemtuzumab on allospecific regulatory T-cell generation

Levitsky, J., Leventhal, J. R., Miller, J., Huang, X., Chen, L., Chandrasekaran, D., Tambur, A. R. & Mathew, J. M., Feb 1 2012, In : Human Immunology. 73, 2, p. 141-149 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Spontaneous operational tolerance in kidney transplant recipients

Leventhal, J., Levitsky, J., Abecassis, M. M., Mathew, J., Tambur, A., Miller, J. & Ildstad, S., May 1 2012, In : American Journal of Transplantation. 12, 5, 1 p.

Research output: Contribution to journalLetter

4 Scopus citations
9 Scopus citations
2011

Allospecific regulatory effects of sirolimus and tacrolimus in the human mixed lymphocyte reaction

Levitsky, J., Gallon, L., Miller, J., Tambur, A. R., Leventhal, J., Flaa, C., Huang, X., Sarraj, B., Wang, E. & Mathew, J. M., Jan 27 2011, In : Transplantation. 91, 2, p. 199-206 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Common gamma chain cytokines promote rapid in vitro expansion of allo-specific human CD8 + suppressor T cells

Yu, Y., Zitzner, J. R., Houlihan, J., Herrera, N., Xu, L., Miller, J., Mathew, J. M., Tambur, A. R. & Luo, X., Dec 14 2011, In : PloS one. 6, 12, e28948.

Research output: Contribution to journalArticle

10 Scopus citations

Microchimerism in promoting graft acceptance in clinical transplantation

Mathew, J. M., Leventhal, J. R. & Miller, J., Aug 1 2011, In : Current opinion in organ transplantation. 16, 4, p. 345-352 8 p.

Research output: Contribution to journalReview article

5 Scopus citations
3 Scopus citations
2010

Immune "tolerance profiles" in donor bone marrow infused kidney transplant patients using multiple ex vivo functional assays

Mathew, J. M., Ciancio, G., Burke, G. W., Garcia-Morales, R. O., Rosen, A., Wang, E., Gomez, C. I., Blomberg, B. B., Fuller, L., Esquenazi, V., Ricordi, C. & Miller, J., Jun 1 2010, In : Human Immunology. 71, 6, p. 566-576 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

Interleukin-10 delivery via mesenchymal stem cells: A novel gene therapy approach to prevent lung ischemia-reperfusion injury

Manning, E., Pham, S., Li, S., Vazquez-Padron, R. I., Mathew, J., Ruiz, P. & Salgar, S. K., Jun 1 2010, In : Human Gene Therapy. 21, 6, p. 713-727 15 p.

Research output: Contribution to journalArticle

58 Scopus citations
2009

Immunopathology of Organ Transplantation

Mathew, JM. & Ruiz, P., 2009, Transplantation Pathology. Ruiz, P. (ed.). New York: Cambridge University Press, p. 1-25

Research output: Chapter in Book/Report/Conference proceedingChapter

Immunoregulatory profiles in liver transplant recipients on different immunosuppressive agents

Levitsky, J., Miller, J., Wang, E., Rosen, A., Flaa, C., Abecassis, M., Mathew, J. & Tambur, A., Mar 1 2009, In : Human Immunology. 70, 3, p. 146-150 5 p.

Research output: Contribution to journalArticle

20 Scopus citations

The human "treg MLR": Immune monitoring for FOXP3+ T regulatory cell generation

Levitsky, J., Miller, J., Leventhal, J., Huang, X., Flaa, C., Wang, E., Tambur, A., Burt, R. K., Gallon, L. & Mathew, J. M., Dec 1 2009, In : Transplantation. 88, 11, p. 1303-1311 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

Tolerance versus immunosuppression: A perspective

Miller, J., Levitsky, J., Mathew, J. & Ciancio, G., Feb 1 2009, In : American Journal of Transplantation. 9, 2, 1 p.

Research output: Contribution to journalLetter

1 Scopus citations
2008

Evaluation of the tolerogenic effects of donor bone marrow cells using a severe combined immunodeficient mouse-human islet transplant model

Mathew, J. M., Blomberg, B., Ricordi, C., Esquenazi, V. & Miller, J., Oct 1 2008, In : Human Immunology. 69, 10, p. 605-613 9 p.

Research output: Contribution to journalArticle

2 Scopus citations
2007

FoxP3 mRNA transcripts and regulatory cells in renal transplant recipients 10 years after donor marrow infusion

Cirocco, R. E., Carreño, M. R., Mathew, J. M., Garcia-Morales, R. O., Fuller, L., Esquenazi, V., Ciancio, G., Burke, G. W., Gaynor, J. J., Blomberg, B. B., Rosen, A., Kleiner, G., Ricordi, C. & Miller, J., Jun 1 2007, In : Transplantation. 83, 12, p. 1611-1619 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

Inhibition of NF-κB during human dendritic cell differentiation generates anergy and regulatory T-cell activity for one but not two human leukocyte antigen DR mismatches

Hernandez, A., Burger, M., Blomberg, B. B., Ross, W. A., Gaynor, J. J., Lindner, I., Cirocco, R., Mathew, J. M., Carreno, M., Jin, Y., Lee, K. P., Esquenazi, V. & Miller, J., Sep 1 2007, In : Human Immunology. 68, 9, p. 715-729 15 p.

Research output: Contribution to journalArticle

20 Scopus citations

Killer cell immunoglobulin-like receptor polymorphisms in HLA-identical kidney transplant recipients: Lack of 2DL2 and 2DS2 may be associated with poor graft function

Cirocco, R. E., Mathew, J. M., Burke, G. W., Esquenazi, V. & Miller, J., Apr 1 2007, In : Tissue Antigens. 69, SUPPL. 1, p. 123-124 2 p.

Research output: Contribution to journalArticle

6 Scopus citations

Transplantation of the spleen: Effect of splenic allograft in human multivisceral transplantation

Kato, T., Tzakis, A. G., Selvaggi, G., Gaynor, J. J., Takahashi, H., Mathew, J., Garcia-Morales, R., Hernandez, E., David, A., Nishida, S., Levi, D., Moon, J., Island, E., Kleiner, G. & Ruiz, P., Sep 1 2007, In : Annals of surgery. 246, 3, p. 436-444 9 p.

Research output: Contribution to journalArticle

44 Scopus citations
2005

Abrogation of the alloreactive responses of cadaveric donor intestinal lymphocytes by intraoperative campath-1H exposure

Mathew, J. M., DeFaria, W., Kato, T., Blomberg, B., Carreno, M., Santiago, S., Weppler, D., Esquenazi, V., Miller, J. & Tzakis, A. G., Mar 2005, In : Transplantation proceedings. 37, 2, p. 1375-1378 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

A randomized trial of three renal transplant induction antibodies: Early comparison of tacrolimus, mycophenolate mofetil, and steroid dosing, and newer immune-monitoring

Ciancio, G., Burke, G. W., Gaynor, J. J., Carreno, M. R., Cirocco, R. E., Mathew, J. M., Mattiazzi, A., Cordovilla, T., Roth, D., Kupin, W., Rosen, A., Esquenazi, V., Tzakis, A. G. & Miller, J., Aug 27 2005, In : Transplantation. 80, 4, p. 457-465 9 p.

Research output: Contribution to journalArticle

176 Scopus citations
2004

Donor bone marrow infusion in deceased and living donor renal transplantation

Ciancio, G., Burke, G. W., Moon, J., Garcia-Morales, R., Rosen, A., Esquenazi, V., Mathew, J., Jin, Y. & Miller, J., Dec 31 2004, In : Yonsei medical journal. 45, 6, p. 998-1003 6 p.

Research output: Contribution to journalReview article

11 Scopus citations

Toward tolerance to human organ transplants: A few additional corollaries and questions

Miller, J., Mathew, J. M. & Esquenazi, V., Mar 27 2004, In : Transplantation. 77, 6, p. 940-942 3 p.

Research output: Contribution to journalReview article

12 Scopus citations
2003

A novel micro-cell-mediated lympholytic assay for the evaluation of regulatory cells in human alloreactive CTL responses

Mathew, J. M., Blomberg, B., Fuller, L., Burke, G. W., Ciancio, G., Kenyon, N., Ricordi, C., Tzakis, A. G., Esquenazi, V. & Miller, J., Jan 15 2003, In : Journal of Immunological Methods. 272, 1-2, p. 67-80 14 p.

Research output: Contribution to journalArticle

7 Scopus citations

Human donor bone marrow cells induce in vitro "suppressor T cells" that functionally suppress autologous B cells

Carreno, M. R., Fuller, L., Mathew, J. M., Ciancio, G., Burke, G. W., Esquenazi, V., Ricordi, C., Tzakis, A. G. & Miller, J., Jan 1 2003, In : Human Immunology. 64, 1, p. 21-30 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Immune responses and their regulation by donor bone marrow cells in clinical organ transplantation

Mathew, J. M., Garcia-Morales, R. O., Carreno, M., Jin, Y., Fuller, L., Blomberg, B., Cirocco, R., Burke, G. W., Ciancio, G., Ricordi, C., Esquenazi, V., Tzakis, A. G. & Miller, J., Jan 1 2003, In : Transplant Immunology. 11, 3-4, p. 307-321 15 p.

Research output: Contribution to journalArticle

37 Scopus citations

Micro-CML assay

Mathew, J. M., Dec 1 2003, In : Modern Aspects of Immunobiology. 3, 2, 1 p.

Research output: Contribution to journalComment/debate