James P Chandler

Professor, Neurological Surgery
Lavin/Fates Professor of Neurological Surgery, Neurological Surgery
Professor, Neurology
Professor, Otolaryngology

Phone312/695-1065
Emailj-chandler@northwestern.edu

1408 Citations

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Personal profile

Research Interests

Brain tumors / neuro-oncology, Spine diseases, Stereotactic radiosurgery

Certifications and Licenses

Neurological Surgery

Training Experience

1996	Fellowship, Sao Paulo Neurological Institute, Brazil
1996	Residency, Northwestern University, McGaw Medical Center (Northwestern Memorial Hospital)
1997	Fellowship, Georgetown University Hospital

Education/Academic qualification

MD, University of Maryland

… → 1990

Research interests

Acoustic Neuroma
Brain Injury
Cancer Biology
Interventional Neurosurgery
Neuro-Oncology
Neurobiology
Neurosurgery
Skull Base Surgery

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Neoplasm Metastasis Medicine & Life Sciences

temozolomide Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2004 2023

3 Active
15 Finished

SPORE for Translational Approaches to Brain Cancer

Ahmed, A. U., Balyasnikova, I. V., Bartom, E. T., Brat, D. J., Chandler, J. P., Cheng, S., Horbinski, C. M., Hu, B., James, C. D., Kumthekar, P. U., Leikin, R. G., Lesniak, M. S., Liu, B. P., Lukas, R. V., Mirkin, C. A., Platanias, L. C., Sachdev, S., Scholtens, D. M., Stegh, A. H., Stupp, R. & Wainwright, D. A.

National Cancer Institute

8/17/18 → 7/31/23

Project: Research project

Brain Neoplasms

Glioblastoma

Therapeutics

Neoplasms

Survival

DRUG ICT-107-301-STING (Study of Immunotherapy in Newly Diagnosed Glioblastoma): A Phase III randomized double-blind, controlled study of ICT-107 with maintenance temozolomide (TMZ) in newly diagnosed glioblastoma following resection and concomitant TMZ c

Chandler, J. P.

Novella Clinical, LLC, ImmunoCellular Therapeutics, Ltd.

12/1/16 → 12/1/19

Project: Research project

Institutional Membership-Alliance for Clinical Trials in Oncology

Bentrem, D. J., Chandler, J. P., DeCamp Jr, M. M., Halverson, A. L., Hoffman Marymont, M., Khan, S. A., Kumthekar, P. U., Mao, Q. & Raizer, J. J.

Alliance for Clinical Trials in Oncology, National Cancer Institute

6/26/13 → 4/30/23

Project: Research project

National Cancer Institute (U.S.)

Organized Financing

Clinical Trials

Prot # ICT-107-201: A Randomized, Double-blind, Controlled Phase IIb Study of the Safety and Efficacy of ICT-107 in Newly Diagnosed Patients with Glioblastoma Multiforme (GBM) Following Resection and Chemoradiation

Chandler, J. P. & Raizer, J. J.

Aptiv Solutions, ImmunoCellular Therapeutics, Ltd.

7/19/11 → 7/19/17

Project: Research project

Analysis of Out-of-Pocket Costs of Care and Quality of Life Concordance for Patient with Malignant Gliomas and Their Caregivers

Chandler, J. P. & Raizer, J. J.

American Brain Tumor Association

8/1/08 → 3/9/12

Project: Research project

Research Output 1996 2019

1408 Citations
56 Article
12 Chapter
5 Review article
2 Comment/debate
1 More
- 1 Letter

1 Citation (Scopus)

Race influences survival in glioblastoma patients with KPS ≥ 80 and associates with genetic markers of retinoic acid metabolism

Wu, M., Miska, J. M., Xiao, T., Zhang, P., Kane, J. R., Balyasnikova, I. V., Chandler, J. P., Horbinski, C. M. & Lesniak, M. S., Apr 15 2019, In : Journal of Neuro-Oncology. 142, 2, p. 375-384 10 p.

Research output: Contribution to journal › Article

Glioblastoma

Tretinoin

Genetic Markers

African Americans

Glioma

Stereotactic radiosurgery for the treatment of brain metastasis from gastrointestinal primary cancers

Paudel, N., Helenowski, I., Kane, L., Sachdev, S., Bloch, O., Tate, M. C., Chandler, J. P. & Kruser, T. J., Jan 1 2019, In : Journal of Radiosurgery and SBRT. 6, 1, p. 27-34 8 p.

Research output: Contribution to journal › Article

Gastrointestinal Neoplasms

Radiosurgery

Neoplasm Metastasis

Brain

Therapeutics

5 Citations (Scopus)

Endoscopic Approach to Clival Chordomas: The Northwestern Experience

Rahme, R. J., Arnaout, O. M., Sanusi, O. R., Kesavabhotla, K. & Chandler, J. P., Feb 1 2018, In : World neurosurgery. 110, p. e231-e238

Research output: Contribution to journal › Article

Chordoma

Tumor Burden

Recurrence

Adjuvant Radiotherapy

Retreatment

13 Citations (Scopus)

Gross total resection and adjuvant radiotherapy most significant predictors of improved survival in patients with atypical meningioma

Rydzewski, N. R., Lesniak, M. S., Chandler, J. P., Kalapurakal, J. A., Pollom, E., Tate, M. C., Bloch, O., Kruser, T., Dalal, P. & Sachdev, S., Feb 15 2018, In : Cancer. 124, 4, p. 734-742 9 p.

Research output: Contribution to journal › Article

Adjuvant Radiotherapy

Meningioma

Survival

Radiotherapy

Neoplasms

Postoperative stereotactic radiosurgery for patients with resected brain metastases: a volumetric analysis

Patel, R. A., Lock, D., Helenowski, I. B., Chandler, J. P., Tate, M. C., Bloch, O., Sachdev, S. & Kruser, T. J., Nov 15 2018, In : Journal of Neuro-Oncology. 140, 2, p. 395-401 7 p.

Research output: Contribution to journal › Article

Radiosurgery

Neoplasm Metastasis

Recurrence

Multivariate Analysis

Brain