Grants per year
- 1 - 25 out of 52 results
Search results
-
Active
Prot #RIN‐PF‐302: An Open‐label Extension Study of Inhaled Treprostinil in Subjects with Idiopathic Pulmonary Fibrosis
Bemiss, B. (PD/PI) & Dematte D'Amico, J. E. (PD/PI)
United Therapeutics Corporation
8/18/23 → 8/18/26
Project: Research project
-
Prot #GB44496: A Two‐Cohort, Phase II, Multicenter, Randomized, Double‐Blind, Parallel‐Group, Placebo‐Controlled Study Evaluating the Efficacy and Safety of Vixarelimab Compared with Placebo in Patients with Idiopathic Pulmonary Fibrosis and in Patients
Bemiss, B. (PD/PI) & Dematte D'Amico, J. E. (PD/PI)
PPD Investigator Services, LLC, Genentech, Inc
6/26/23 → 8/10/27
Project: Research project
-
Prot #1366-0031: A Phase II, Randomised, Placebo-controlled, Double-blind, Parallel-group, Efficacy and Safety Study of at Least 48 Weeks of Oral BI 685509 Treatment in Adults with Early Progressive Diffuse Cutaneous Systemic Sclerosis
Dematte D'Amico, J. E. (PD/PI)
Boehringer Ingelheim Pharmaceuticals, Inc.
3/24/23 → 3/24/26
Project: Research project
-
Molecular Biomarkers To Guide Therapy In The Systemic Sclerosis-Associated Interstitial Lung Disease
Misharin, A. (PD/PI) & Dematte D'Amico, J. E. (Co-PD/PI)
10/19/22 → 10/18/25
Project: Research project
-
Prot #RIN-PF-301: A Randomized, Double-blind, Placebo-controlled, Phase 3 Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects with Idiopathic Pulmonary Fibrosis
Bemiss, B. (PD/PI) & Dematte D'Amico, J. E. (PD/PI)
United Therapeutics Corporation
4/28/22 → 4/30/26
Project: Research project
-
Idiopathic Pulmonary Fibrosis Prospective Outcomes (IPF-PRO) and Chronic Fibrosing Interstitial Lung Disease with Progressive Phenotype Prospective Outcomes (ILD-PRO) Registry
Bemiss, B. (PD/PI), Dematte D'Amico, J. E. (PD/PI) & Dematte D'Amico, J. E. (PD/PI)
Duke University, Boehringer Ingelheim Pharmaceuticals, Inc.
8/21/20 → 8/21/28
Project: Research project
-
Finished
-
Prot #1199-0324: Study of Pulmonary Rehabilitation In Nintedanib Treated Patients with IPF: Improvements in Activity, Exercise Endurance Time, and QoL
Dematte D'Amico, J. E. (PD/PI) & Bhorade, S. M. (Other)
Boehringer Ingelheim Pharmaceuticals, Inc.
2/28/19 → 2/28/22
Project: Research project
-
Prot #ML30172: Scleroderma Lung Study III (SLS III): Combining the anti-fibrotic effects of pirfenidone (PFD) with mycophenolate (MMF) for treating scleroderma-related interstitial lung disease
Dematte D'Amico, J. E. (PD/PI)
University of California, Los Angeles, Genentech, Inc
1/24/18 → 1/24/24
Project: Research project
-
Prot #IIS2017-10679: Identifying Unique Pathogenic Macrophages in Systemic Sclerosis-ILD using High Throughput Single-cell RNA-Seq
Gottardi, C. J. (PD/PI), Bhorade, S. M. (Co-PD/PI), Dematte D'Amico, J. E. (Co-Investigator), Hinchcliff, M. E. (Co-Investigator) & Lam, A. P. (Other)
Boehringer Ingelheim Pharmaceuticals, Inc.
12/28/17 → 12/28/24
Project: Research project
-
Wnt-beta-catenin cross interactions in alveolar macrophages and epithelial cells in persistence of SSc-ILD
Dematte D'Amico, J. E. (PD/PI), Dematte D'Amico, J. E. (PD/PI), Gottardi, C. J. (PD/PI), Gottardi, C. J. (PD/PI), Hinchcliff, M. E. (PD/PI), Hinchcliff, M. E. (PD/PI), Lam, A. P. (PD/PI), Lam, A. P. (PD/PI), Berdnikovs, S. (Co-Investigator), Berdnikovs, S. (Co-Investigator), Budinger, G. S. (Co-Investigator), Budinger, G. S. (Co-Investigator), Dematte D'Amico, J. E. (Co-Investigator), Dematte D'Amico, J. E. (Co-Investigator), Hinchcliff, M. E. (Co-Investigator), Misharin, A. (Co-Investigator) & Misharin, A. (Co-Investigator)
National Heart, Lung, and Blood Institute
12/22/17 → 11/30/24
Project: Research project
-
Prot #1199.247: A double blind, randomized, placebo-controlled trial evaluating the efficacy and safety of nintedanib over 52 weeks in patients with Progressive Fibrosing Interstitial Lung Disease (PF-ILD)
Dematte D'Amico, J. E. (PD/PI)
Boehringer Ingelheim Pharmaceuticals, Inc.
8/16/17 → 2/16/24
Project: Research project
-
Prot #EMR200017-014: A Phase II, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Trial to Evaluate the Efficacy and Safety of Abituzuma in Subjects with Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD)
Dematte D'Amico, J. E. (PD/PI)
Quintiles, Inc., EMD Serono Research & Development Institute, Inc.
9/12/16 → 9/12/19
Project: Research project
-
Prot #1199.214: A double blind, randomised, placebo-controlled trial evaluating efficacy and safety of oral nintedanib treatment for at least 52 weeks in patients with ‘Systemic Sclerosis associated Interstitial Lung Disease’(SSc-ILD)
Dematte D'Amico, J. E. (PD/PI)
Boehringer Ingelheim Pharmaceuticals, Inc.
2/11/16 → 11/30/21
Project: Research project
-
Prot #PSSc-001: An Open-Label, Randomized, Phase 2 Study of the Safety and Tolerability of Pirfenidone when Administered to Patients with Systemic Sclerosis−Related Interstitial Lung Disease; The LOTUSS Trial: An Open-Label, RandOmized, Phase 2 STUdy of t
Dematte D'Amico, J. E. (PD/PI)
9/5/13 → 9/5/16
Project: Research project
-
Prot# ACE114622: A Two Part Study to Investigate the Safety, Tolerability, Pharmacokinetics and Parmacodynamics of GSK2586881 in Patients with Acute Lung Injury
Wunderink, R. G. (PD/PI), Dematte D'Amico, J. E. (Co-PD/PI) & Weiss, C. H. (Co-PD/PI)
5/8/12 → 10/10/14
Project: Research project
-
Prot# AC-063B201: A Phase 2, Multi-center, Double-blind, Randomized, Placebo-controlled Study to Evaluate the Effects of Inhaled Iloprost on Endurance Time During Cardiopulmonary Exercise Testing in Patients with Pulmonary Hypertension Secondary to Chroni
Cuttica, M. J. (PD/PI), Dematte D'Amico, J. E. (Co-PD/PI), Kalhan, R. (Co-PD/PI), Rosenberg, S. R. (Co-PD/PI) & Shah, S. J. (Co-PD/PI)
3/19/12 → 3/19/15
Project: Research project
-
PKD11791: A Randomized, Double-blind, Placebo-Controlled Trial to Assess the Pharmacokinetics, Pharmacodynamics and Safety of a Single Dose of SAR279356 in Patients Hospitalized in Intensive Care Unit and on Mechanical Ventilation
Wunderink, R. G. (PD/PI), Dematte D'Amico, J. E. (Co-PD/PI) & Prickett, M. (Co-PD/PI)
10/27/11 → 10/27/14
Project: Research project
-
Prot#RIN-PH-403: A Postmarketing Observational Study to Assess Respiratory Tract Adverse Events in Pulmonary Arterial Hypertension Patients Treated with Tyvaso (Treprostinil) Inhalation Solution
Cuttica, M. J. (PD/PI), Dematte D'Amico, J. E. (Co-PD/PI) & Shah, S. J. (Co-PD/PI)
United Therapeutics Corporation
9/29/11 → 2/28/15
Project: Research project
-
(TERMINATED 05/01/2012) Prot# BA-I-H-0903: Randomized, Multi-Centre, Controlled Clinical Study on the Effect of the S.A.F.E. bt Therapy on Disease Severity and Inflammation in Mechanically-Ventilated Subjects due to Severe Sepsis
Wunderink, R. G. (PD/PI), Cuttica, M. J. (Co-PD/PI), Dematte D'Amico, J. E. (Co-PD/PI), Ghossein, C. (Co-PD/PI) & Weiss, C. H. (Co-PD/PI)
Theorem Clinical Research, SAFE bt, INC.
6/10/11 → 6/10/14
Project: Research project
-
Prot#BSTE-0409: Rapid Evaluation of Acute Kidney Injury with NGAL in Acutely Ill Patients in the ICU (REAL-ICU)
Wunderink, R. G. (PD/PI), Dematte D'Amico, J. E. (Co-PD/PI) & Weiss, C. H. (Co-PD/PI)
4/20/11 → 4/19/14
Project: Research project
-
Prot# PAB05: Estimation of the Incidence of Ventilator-Associated Pneumonia Caused by Pseudomonas aeruginosa (VAP-Pa)
Wunderink, R. G. (PD/PI), Dematte D'Amico, J. E. (Co-PD/PI) & Weiss, C. H. (Co-PD/PI)
Clinical Financial Services, LLC, Sanofi Pasteur Limited
3/21/11 → 3/21/14
Project: Research project
-
AGMT 02/10/11: CONFRONT PAH: CombinatiON up-FRON t Therapy for PAH-A Phase 4, Randomized, Multicenter Study of Inhaled Treprostinil in Treatment-naive Pulmonary Arterial Hypertension Patients Starting on Tadalafil
Cuttica, M. J. (PD/PI), Dematte D'Amico, J. E. (Co-PD/PI) & Shah, S. J. (Co-PD/PI)
United Therapeutics Corporation
2/10/11 → 2/10/17
Project: Research project
-
Prot# AC-063A402: A Phase IIIb, Multicenter, Open-Label Study of Patients with Pulmonary Arterial Hypertension Treated with Iloprost (Inhalation) Evaluating Safety and Inhalation Times When Converting from Power Disc-6 to Power Disc-15 With the I-Neb AAD
Dematte D'Amico, J. E. (PD/PI), Cuttica, M. J. (Co-PD/PI) & Shah, S. J. (Co-PD/PI)
Paragon Biomedical, Inc., Actelion Ltd.
5/14/09 → 5/14/12
Project: Research project