Grants per year
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Active
Prot #RIN‐PF‐302: An Open‐label Extension Study of Inhaled Treprostinil in Subjects with Idiopathic Pulmonary Fibrosis
Dematte D'Amico, J. E. (PD/PI)
United Therapeutics Corporation
8/18/23 → 8/18/26
Project: Research project
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Prot #GB44496: A Two‐Cohort, Phase II, Multicenter, Randomized, Double‐Blind, Parallel‐Group, Placebo‐Controlled Study Evaluating the Efficacy and Safety of Vixarelimab Compared with Placebo in Patients with Idiopathic Pulmonary Fibrosis and in Patients
Dematte D'Amico, J. E. (PD/PI)
PPD Investigator Services, LLC, Genentech, Inc
6/26/23 → 8/10/27
Project: Research project
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Prot #1366-0031: A Phase II, Randomised, Placebo-controlled, Double-blind, Parallel-group, Efficacy and Safety Study of at Least 48 Weeks of Oral BI 685509 Treatment in Adults with Early Progressive Diffuse Cutaneous Systemic Sclerosis
Dematte D'Amico, J. E. (PD/PI)
Boehringer Ingelheim Pharmaceuticals, Inc.
3/24/23 → 3/24/26
Project: Research project
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Molecular Biomarkers To Guide Therapy In The Systemic Sclerosis-Associated Interstitial Lung Disease
Misharin, A. (PD/PI) & Dematte D'Amico, J. E. (Co-PD/PI)
10/19/22 → 10/18/25
Project: Research project
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Idiopathic Pulmonary Fibrosis Prospective Outcomes (IPF-PRO) and Chronic Fibrosing Interstitial Lung Disease with Progressive Phenotype Prospective Outcomes (ILD-PRO) Registry
Dematte D'Amico, J. E. (PD/PI)
Duke University, Boehringer Ingelheim Pharmaceuticals, Inc.
8/21/20 → 8/21/25
Project: Research project
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Prot #IIS2017-10679: Identifying Unique Pathogenic Macrophages in Systemic Sclerosis-ILD using High Throughput Single-cell RNA-Seq
Gottardi, C. (PD/PI), Bhorade, S. M. (Co-PD/PI), Dematte D'Amico, J. E. (Co-Investigator), Hinchcliff, M. E. (Co-Investigator) & Lam, A. P. (Other)
Boehringer Ingelheim Pharmaceuticals, Inc.
12/28/17 → 12/28/24
Project: Research project
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Wnt-beta-catenin cross interactions in alveolar macrophages and epithelial cells in persistence of SSc-ILD
Dematte D'Amico, J. E. (PD/PI), Dematte D'Amico, J. E. (PD/PI), Gottardi, C. (PD/PI), Gottardi, C. (PD/PI), Hinchcliff, M. E. (PD/PI), Hinchcliff, M. E. (PD/PI), Lam, A. P. (PD/PI), Lam, A. P. (PD/PI), Berdnikovs, S. (Co-Investigator), Berdnikovs, S. (Co-Investigator), Budinger, G. S. (Co-Investigator), Budinger, G. S. (Co-Investigator), Dematte D'Amico, J. E. (Co-Investigator), Dematte D'Amico, J. E. (Co-Investigator), Hinchcliff, M. E. (Co-Investigator), Misharin, A. (Co-Investigator) & Misharin, A. (Co-Investigator)
National Heart, Lung, and Blood Institute
12/22/17 → 11/30/24
Project: Research project
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Finished
Prot #1199-0324: Study of Pulmonary Rehabilitation In Nintedanib Treated Patients with IPF: Improvements in Activity, Exercise Endurance Time, and QoL
Dematte D'Amico, J. E. (PD/PI) & Bhorade, S. M. (Other)
Boehringer Ingelheim Pharmaceuticals, Inc.
2/28/19 → 2/28/22
Project: Research project
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Prot #ML30172: Scleroderma Lung Study III (SLS III): Combining the anti-fibrotic effects of pirfenidone (PFD) with mycophenolate (MMF) for treating scleroderma-related interstitial lung disease
Dematte D'Amico, J. E. (PD/PI)
University of California, Los Angeles, Genentech, Inc
1/24/18 → 1/24/24
Project: Research project
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Prot #1199.247: A double blind, randomized, placebo-controlled trial evaluating the efficacy and safety of nintedanib over 52 weeks in patients with Progressive Fibrosing Interstitial Lung Disease (PF-ILD)
Dematte D'Amico, J. E. (PD/PI)
Boehringer Ingelheim Pharmaceuticals, Inc.
8/16/17 → 2/16/24
Project: Research project
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Prot #EMR200017-014: A Phase II, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Trial to Evaluate the Efficacy and Safety of Abituzuma in Subjects with Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD)
Dematte D'Amico, J. E. (PD/PI)
Quintiles, Inc., EMD Serono Research & Development Institute, Inc.
9/12/16 → 9/12/19
Project: Research project
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Prot #1199.214: A double blind, randomised, placebo-controlled trial evaluating efficacy and safety of oral nintedanib treatment for at least 52 weeks in patients with ‘Systemic Sclerosis associated Interstitial Lung Disease’(SSc-ILD)
Dematte D'Amico, J. E. (PD/PI)
Boehringer Ingelheim Pharmaceuticals, Inc.
2/11/16 → 11/30/21
Project: Research project
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Prot #PSSc-001: An Open-Label, Randomized, Phase 2 Study of the Safety and Tolerability of Pirfenidone when Administered to Patients with Systemic Sclerosis−Related Interstitial Lung Disease; The LOTUSS Trial: An Open-Label, RandOmized, Phase 2 STUdy of t
Dematte D'Amico, J. E. (PD/PI)
9/5/13 → 9/5/16
Project: Research project
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Prot# ACE114622: A Two Part Study to Investigate the Safety, Tolerability, Pharmacokinetics and Parmacodynamics of GSK2586881 in Patients with Acute Lung Injury
Wunderink, R. G. (PD/PI), Dematte D'Amico, J. E. (Co-PD/PI) & Weiss, C. H. (Co-PD/PI)
5/8/12 → 10/10/14
Project: Research project
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Prot# AC-063B201: A Phase 2, Multi-center, Double-blind, Randomized, Placebo-controlled Study to Evaluate the Effects of Inhaled Iloprost on Endurance Time During Cardiopulmonary Exercise Testing in Patients with Pulmonary Hypertension Secondary to Chroni
Cuttica, M. J. (PD/PI), Dematte D'Amico, J. E. (Co-PD/PI), Kalhan, R. (Co-PD/PI), Rosenberg, S. R. (Co-PD/PI) & Shah, S. J. (Co-PD/PI)
3/19/12 → 3/19/15
Project: Research project
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PKD11791: A Randomized, Double-blind, Placebo-Controlled Trial to Assess the Pharmacokinetics, Pharmacodynamics and Safety of a Single Dose of SAR279356 in Patients Hospitalized in Intensive Care Unit and on Mechanical Ventilation
Wunderink, R. G. (PD/PI), Dematte D'Amico, J. E. (Co-PD/PI) & Prickett, M. (Co-PD/PI)
10/27/11 → 10/27/14
Project: Research project
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Prot#RIN-PH-403: A Postmarketing Observational Study to Assess Respiratory Tract Adverse Events in Pulmonary Arterial Hypertension Patients Treated with Tyvaso (Treprostinil) Inhalation Solution
Cuttica, M. J. (PD/PI), Dematte D'Amico, J. E. (Co-PD/PI) & Shah, S. J. (Co-PD/PI)
United Therapeutics Corporation
9/29/11 → 2/28/15
Project: Research project
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(TERMINATED 05/01/2012) Prot# BA-I-H-0903: Randomized, Multi-Centre, Controlled Clinical Study on the Effect of the S.A.F.E. bt Therapy on Disease Severity and Inflammation in Mechanically-Ventilated Subjects due to Severe Sepsis
Wunderink, R. G. (PD/PI), Cuttica, M. J. (Co-PD/PI), Dematte D'Amico, J. E. (Co-PD/PI), Ghossein, C. (Co-PD/PI) & Weiss, C. H. (Co-PD/PI)
Theorem Clinical Research, SAFE bt, INC.
6/10/11 → 6/10/14
Project: Research project
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Prot#BSTE-0409: Rapid Evaluation of Acute Kidney Injury with NGAL in Acutely Ill Patients in the ICU (REAL-ICU)
Wunderink, R. G. (PD/PI), Dematte D'Amico, J. E. (Co-PD/PI) & Weiss, C. H. (Co-PD/PI)
4/20/11 → 4/19/14
Project: Research project
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Prot# PAB05: Estimation of the Incidence of Ventilator-Associated Pneumonia Caused by Pseudomonas aeruginosa (VAP-Pa)
Wunderink, R. G. (PD/PI), Dematte D'Amico, J. E. (Co-PD/PI) & Weiss, C. H. (Co-PD/PI)
Clinical Financial Services, LLC, Sanofi Pasteur Limited
3/21/11 → 3/21/14
Project: Research project
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AGMT 02/10/11: CONFRONT PAH: CombinatiON up-FRON t Therapy for PAH-A Phase 4, Randomized, Multicenter Study of Inhaled Treprostinil in Treatment-naive Pulmonary Arterial Hypertension Patients Starting on Tadalafil
Cuttica, M. J. (PD/PI), Dematte D'Amico, J. E. (Co-PD/PI) & Shah, S. J. (Co-PD/PI)
United Therapeutics Corporation
2/10/11 → 2/10/17
Project: Research project
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Prot# AC-063A402: A Phase IIIb, Multicenter, Open-Label Study of Patients with Pulmonary Arterial Hypertension Treated with Iloprost (Inhalation) Evaluating Safety and Inhalation Times When Converting from Power Disc-6 to Power Disc-15 With the I-Neb AAD
Dematte D'Amico, J. E. (PD/PI), Cuttica, M. J. (Co-PD/PI) & Shah, S. J. (Co-PD/PI)
Paragon Biomedical, Inc., Actelion Ltd.
5/14/09 → 5/14/12
Project: Research project