• 9208 Citations
1989 …2019

Research output per year

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Personal profile

Research Interests

My primary research interests are in molecular mechanisms of gene regulation, particularly those involved in neural development and neural degeneration. My lab is focusing on two areas, RNA regulation and mechanisms underlying cell migration with particular interest in molecular/cellular mechanisms underlying neurodevelopmental disorders, cancer invasion/metastasis and neurodegenerative diseases.

Education/Academic qualification

PhD, Stanford University

… → 1991

MD, Shanghai Second Medical University

… → 1986

Research interests

  • Aging
  • Alzheimer's Disease
  • Amyloidosis
  • Lung Cancer / Chest Cancer
  • Neuro-Oncology
  • Neurogenetics
  • Neurology
  • Pancreatic Cancer

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  • Pilot 1 Year 01

    Wu, J.

    National Cancer Institute


    Project: Research project

  • Research Output

    A crucial role for Arf6 in the response of commissural axons to Slit

    Kinoshita-Kawada, M., Hasegawa, H., Hongu, T., Yanagi, S., Kanaho, Y., Masai, I., Mishima, T., Chen, X., Tsuboi, Y., Rao, Y., Yuasa-Kawada, J. & Wu, J. Y., Feb 1 2019, In : Development (Cambridge). 146, 3, dev172106.

    Research output: Contribution to journalArticle

  • 4 Scopus citations

    Reduced USP33 expression in gastric cancer decreases inhibitory effects of Slit2-Robo1 signalling on cell migration and EMT

    Xia, Y., Wang, L., Xu, Z., Kong, R., Wang, F., Yin, K., Xu, J., Li, B., He, Z., Wang, L., Xu, H., Zhang, D., Yang, L., Wu, J. Y. & Xu, Z., May 2019, In : Cell Proliferation. 52, 3, e12606.

    Research output: Contribution to journalArticle

    Open Access
  • 7 Scopus citations

    TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response

    Wang, P., Deng, J., Dong, J., Liu, J., Bigio, E. H., Mesulam, M., Wang, T., Sun, L., Wang, L., Lee, A. Y. L., McGee, W. A., Chen, X., Fushimi, K., Zhu, L. & Wu, J. Y., May 2019, In : PLoS genetics. 15, 5, e1007947.

    Research output: Contribution to journalArticle

    Open Access
  • 16 Scopus citations

    FUS interacts with ATP synthase beta subunit and induces mitochondrial unfolded protein response in cellular and animal models

    Deng, J., Wang, P., Chen, X., Cheng, H., Liu, J., Fushimi, K., Zhu, L. & Wu, J. Y., Oct 9 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 41, p. E9678-E9686

    Research output: Contribution to journalArticle

  • 13 Scopus citations

    Measure and model a 3-D space-variant PSF for fluorescence microscopy image deblurring

    Chen, Y., Chen, M., Zhu, L., Wu, J. Y., Du, S. & Li, Y., May 28 2018, In : Optics Express. 26, 11, p. 14375-14391 17 p.

    Research output: Contribution to journalArticle

  • 3 Scopus citations