Grants per year
Personal profile
Research Interests
My primary research interests are in molecular mechanisms of gene regulation, particularly those involved in neural development and neural degeneration. My lab is focusing on two areas, RNA regulation and mechanisms underlying cell migration with particular interest in molecular/cellular mechanisms underlying neurodevelopmental disorders, cancer invasion/metastasis and neurodegenerative diseases.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Cancer Biology, Stanford University
… → 1991
MD, Medicine, Shanghai Second Medical University
… → 1986
Research interests keywords
- Aging
- Alzheimer's Disease
- Amyloidosis
- Lung Cancer / Chest Cancer
- Neuro-Oncology
- Neurogenetics
- Neurology
- Pancreatic Cancer
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Collaborations and top research areas from the last five years
Grants
- 23 Finished
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Mitochondrial Stress Response in FUS proteinopathy and related dementia
Kessler, J., Fushimi, K., Kiskinis, E. & Wu, J.
9/30/19 → 9/30/22
Project: Research project
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RNA binding protein networks in tau pathogenesis
Vassar, R. J., Fushimi, K. & Wu, J.
9/30/19 → 8/31/20
Project: Research project
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The Role of Mitochondria in TDP-43 Proteinopathy
Wu, J., Fushimi, K., Kiskinis, E. & Ozdinler, H.
National Institute of Neurological Disorders and Stroke
9/30/18 → 6/30/23
Project: Research project
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Biostation CT (Cell Tracker)
Rappoport, J. Z., Arvanitis, C., Burridge, P., Chandel, N., George, A. L., Getsios, S., Green, K. J., Horiuchi, D., Kessler, J., Lavker, R. M., Mazar, A. P., McNally, E. M., Paller, A., Shilatifard, A., Swanson, G. T. & Wu, J.
Office of the Director, National Institutes of Health
4/1/17 → 3/31/18
Project: Research project
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Regulation of tau expression in Alzheimer’s disease and aging
Icahn School of Medicine at Mount Sinai, National Institute on Aging
7/15/16 → 3/31/21
Project: Research project
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Neuronal guidance genes in health and diseases
Yuasa-Kawada, J., Kinoshita-Kawada, M., Tsuboi, Y. & Wu, J. Y., Apr 2023, In: Protein and Cell. 14, 4, p. 238-261 24 p.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
Super-resolution SRS microscopy with A-PoD
Jang, H., Li, Y., Fung, A. A., Bagheri, P., Hoang, K., Skowronska-Krawczyk, D., Chen, X., Wu, J. Y., Bintu, B. & Shi, L., Mar 2023, In: Nature Methods. 20, 3, p. 448-458 11 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Detection of orthologous exons and isoforms using EGIO
Ma, J., Wu, J. Y. & Zhu, L., Oct 1 2022, In: Bioinformatics. 38, 19, p. 4474-4480 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
MICAL2PV suppresses the formation of tunneling nanotubes and modulates mitochondrial trafficking
Wang, F., Chen, X., Cheng, H., Song, L., Liu, J., Caplan, S., Zhu, L. & Wu, J. Y., Jul 5 2021, In: EMBO Reports. 22, 7, e52006.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Tongue as a first-line immune organ?
Wu, J. Y., Mar 2021, In: Protein and Cell. 12, 3, p. 162-164 3 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access1 Scopus citations
Datasets
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2GNC : Crystal structure of srGAP1 SH3 domain in the slit-robo signaling pathway
Li, X. (Contributor), Liu, Y. (Contributor), Gao, F. (Contributor), Bartlam, M. (Contributor), Wu, J. (Contributor) & Rao, Z. (Contributor), RCSB-PDB, 2006
DOI: 10.2210/pdb2gnc/pdb, https://www.rcsb.org/structure/2GNC
Dataset