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Jason H Brickner

  • 2363 Citations
19942019

Research output per year

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Personal profile

Research Interests

DNA and proteins are non-randomly localized within the nucleus of the cell.  The Brickner lab studies how cells control the position of genes within the nucleus, and how gene positioning affects gene expression.  When genes are activated or repressed, their position in the nucleus often changes.  The lab has identified DNA "zip codes" in the promoters of genes that control their positioning, transcription and, through an epigenetic mechanism, chromatin structure.

Education/Academic qualification

Biochemistry, PhD, Stanford University

1992 → 1998

Biological Sciences, BA, University of California at Santa Barbara

1988 → 1992

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Grants

DNA zip codes and the spatial organization of the yeast genome

Brickner, J. H.

National Institute of General Medical Sciences

9/1/17 → 7/31/21

Project: Research project

    • Equipment supplement for Defining the molecular and cellular mechanism of epigenetic transcriptional memory

    Brickner, J. H.

    National Institute of General Medical Sciences

    8/1/16 → 7/31/20

    Project: Research project

    • Defining the molecular and cellular mechanism of epigenetic transcriptional memory

    Brickner, J. H.

    National Institute of General Medical Sciences

    8/1/16 → 7/31/20

    Project: Research project

    • Outreach Pilot 02 (Brickner)

    Brickner, J. H. & O'Halloran, T. V.

    National Cancer Institute

    5/19/15 → 4/30/21

    Project: Research project

    • Subproject for Cellular and Molecular Basis of Disease Training Program

    Brickner, J. H. & Carthew, R. W.

    National Institute of General Medical Sciences

    7/1/16 → 6/30/18

    Project: Research project

    Research Output

    The Role of Transcription Factors and Nuclear Pore Proteins in Controlling the Spatial Organization of the Yeast Genome

    Brickner, D. G., Randise-Hinchliff, C., Corbin, M. L., Liang, J. M., Kim, S., Sump, B., D'Urso, A., Kim, S. H., Satomura, A., Schmit, H., Coukos, R., Hwang, S., Watson, R. & Brickner, J. H., Jun 17 2019, In : Developmental Cell. 49, 6, p. 936-947.e4

    Research output: Contribution to journal › Article

    • 5 Scopus citations

    Nuclear pore complex in genome organization and gene expression in yeast

    Randise-Hinchliff, C. & Brickner, J. H., Jan 1 2018, Nuclear Pore Complexes in Genome Organization, Function and Maintenance. Springer International Publishing, p. 87-109 23 p.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

    • 1 Scopus citations

    Epigenetic transcriptional memory

    D’Urso, A. & Brickner, J. H., Jun 1 2017, In : Current Genetics. 63, 3, p. 435-439 5 p.

    Research output: Contribution to journal › Review article

    • 44 Scopus citations

    Epigenetic transcriptional memory of GAL genes depends on growth in glucose and the tup1 transcription factor in saccharomyces cerevisiae

    Sood, V., Cajigas, I., D’Urso, A., Light, W. H. & Brickner, J. H., Jan 1 2017, In : Genetics. 206, 4, p. 1895-1907 13 p.

    Research output: Contribution to journal › Article

    • 8 Scopus citations

    Genetic and epigenetic control of the spatial organization of the genome

    Brickner, J., Feb 1 2017, In : Molecular biology of the cell. 28, 3, p. 364-369 6 p.

    Research output: Contribution to journal › Review article

    • 6 Scopus citations