Grants per year
Personal profile
Research Interests
DNA and proteins are non-randomly localized within the nucleus of the cell. The Brickner lab studies how cells control the position of genes within the nucleus, and how gene positioning affects gene expression. When genes are activated or repressed, their position in the nucleus often changes. The lab has identified DNA "zip codes" in the promoters of genes that control their positioning, transcription and, through an epigenetic mechanism, chromatin structure.
Education/Academic qualification
Biochemistry, PhD, Stanford University
1992 → 1998
Biological Sciences, BA, University of California at Santa Barbara
1988 → 1992
Fingerprint Dive into the research topics where Jason H Brickner is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Nuclear Pore
Medicine & Life Sciences
Genes
Medicine & Life Sciences
Yeasts
Medicine & Life Sciences
Epigenomics
Medicine & Life Sciences
Yeast
Chemical Compounds
Genome
Medicine & Life Sciences
Chromatin
Medicine & Life Sciences
Porins
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2006 2021
DNA zip codes and the spatial organization of the yeast genome
National Institute of General Medical Sciences
9/1/17 → 7/31/21
Project: Research project
Yeasts
Genome
DNA
Genes
Transcription Factors
Equipment supplement for Defining the molecular and cellular mechanism of epigenetic transcriptional memory
National Institute of General Medical Sciences
8/1/16 → 7/31/20
Project: Research project
Epigenomics
Equipment and Supplies
Genes
Nuclear Pore
Porins
Defining the molecular and cellular mechanism of epigenetic transcriptional memory
National Institute of General Medical Sciences
8/1/16 → 7/31/20
Project: Research project
Epigenomics
Genes
Nuclear Pore
Porins
Yeasts
Outreach Pilot 02 (Brickner)
Brickner, J. H. & O'Halloran, T. V.
5/19/15 → 4/30/20
Project: Research project
Oncology
Subproject for Cellular and Molecular Basis of Disease Training Program
Brickner, J. H. & Carthew, R. W.
National Institute of General Medical Sciences
7/1/16 → 6/30/18
Project: Research project
Research Output 1994 2019
1
Citation
(Scopus)
The Role of Transcription Factors and Nuclear Pore Proteins in Controlling the Spatial Organization of the Yeast Genome
Brickner, D. G., Randise-Hinchliff, C., Corbin, M. L., Liang, J. M., Kim, S., Sump, B., D'Urso, A., Kim, S. H., Satomura, A., Schmit, H., Coukos, R., Hwang, S., Watson, R. & Brickner, J. H., Jun 17 2019, In : Developmental Cell. 49, 6, p. 936-947.e4Research output: Contribution to journal › Article
Nuclear Pore
Porins
Nuclear Proteins
Yeast
Transcription Factors
Nuclear pore complex in genome organization and gene expression in yeast
Randise-Hinchliff, C. & Brickner, J. H., Jan 1 2018, Nuclear Pore Complexes in Genome Organization, Function and Maintenance. Springer International Publishing, p. 87-109 23 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
Nuclear Pore
Gene expression
Yeast
Genes
Yeasts
36
Citations
(Scopus)
Epigenetic transcriptional memory
D’Urso, A. & Brickner, J. H., Jun 1 2017, In : Current Genetics. 63, 3, p. 435-439 5 p.Research output: Contribution to journal › Review article
Epigenomics
Viverridae
Chromatin
Gene Expression
RNA Polymerase II
4
Citations
(Scopus)
Epigenetic transcriptional memory of GAL genes depends on growth in glucose and the tup1 transcription factor in saccharomyces cerevisiae
Sood, V., Cajigas-Rodriguez, I., D’Urso, A., Light, W. H. & Brickner, J. H., Jan 1 2017, In : Genetics. 206, 4, p. 1895-1907 13 p.Research output: Contribution to journal › Article
Epigenomics
Saccharomyces cerevisiae
Transcription Factors
Glucose
Growth
6
Citations
(Scopus)
Genetic and epigenetic control of the spatial organization of the genome
Brickner, J., Feb 1 2017, In : Molecular biology of the cell. 28, 3, p. 364-369 6 p.Research output: Contribution to journal › Review article
Epigenomics
Genome
DNA-Binding Proteins
Chromatin
Chromosomes