• 3906 Citations
1969 …2018

Research output per year

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Personal profile

Research Interests

My research interest has been focused on pharmacology and biophysics of ion channel functions, which are either activated by voltage changes or mediated by ligand receptor binding. Drugs of interest include, but not limited to, general anesthetics, local anesthestics, ethanol and drugs used to the treatment of Alzeheimer's diseases.

Training Experience

1973Postdoctoral Fellowship, Duke University
1976Postdoctoral Fellowship, Duke University

Education/Academic qualification

PhD, University of Missouri

… → 1971

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Grants

Research Output

  • 3906 Citations
  • 136 Article
  • 2 Review article
  • 1 Comment/debate

Blockade of the K ATP channel Kir6.2 by memantine represents a novel mechanism relevant to Alzheimer's disease therapy

Moriguchi, S., Ishizuka, T., Yabuki, Y., Shioda, N., Sasaki, Y., Tagashira, H., Yawo, H., Yeh, J. Z., Sakagami, H., Narahashi, T. & Fukunaga, K., Feb 1 2018, In : Molecular Psychiatry. 23, 2, p. 211-221 11 p.

Research output: Contribution to journalArticle

  • 13 Scopus citations

    CaMKII activity is essential for improvement of memory-related behaviors by chronic rivastigmine treatment

    Moriguchi, S., Tagashira, H., Sasaki, Y., Yeh, J. Z., Sakagami, H., Narahashi, T. & Fukunaga, K., Mar 2014, In : Journal of neurochemistry. 128, 6, p. 927-937 11 p.

    Research output: Contribution to journalArticle

  • 9 Scopus citations

    Immune-stimulated antitumor effect of different molecular weight polysaccharides from Monascus purpureus on human leukemic U937 cells

    Chen, H. H., Chen, Y. Y., Yeh, J. Z., Jiang, C. M. & Wu, M. C., Apr 3 2014, In : CYTA - Journal of Food. 12, 2, p. 134-140 7 p.

    Research output: Contribution to journalArticle

  • 10 Scopus citations

    Application of immunomagnetic particles to enzyme-linked immunosorbent assay (ELISA) for improvement of detection sensitivity of hcg

    Kuo, H. T., Yeh, J. Z., Wu, P. H., Jiang, C. M. & Wu, M. C., Oct 1 2012, In : Journal of Immunoassay and Immunochemistry. 33, 4, p. 377-387 11 p.

    Research output: Contribution to journalArticle

  • 4 Scopus citations