• 3852 Citations
1969 …2018
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Personal profile

Research Interests

My research interest has been focused on pharmacology and biophysics of ion channel functions, which are either activated by voltage changes or mediated by ligand receptor binding. Drugs of interest include, but not limited to, general anesthetics, local anesthestics, ethanol and drugs used to the treatment of Alzeheimer's diseases.

Training Experience

1973Postdoctoral Fellowship, Duke University
1976Postdoctoral Fellowship, Duke University

Education/Academic qualification

PhD, University of Missouri

… → 1971

Research interests

  • Alzheimer's Drug
  • Anesthesiology
  • Biophysics
  • Ion Channels
  • Molecular Pharmacology
  • Nervous System Diseases
  • Neuroscience
  • Pharmacology

Fingerprint Dive into the research topics where Jay Z Yeh is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Grants 2001 2012

Research Output 1969 2018

  • 3852 Citations
  • 136 Article
  • 2 Review article
  • 1 Comment/debate
11 Citations (Scopus)

Blockade of the K ATP channel Kir6.2 by memantine represents a novel mechanism relevant to Alzheimer's disease therapy

Moriguchi, S., Ishizuka, T., Yabuki, Y., Shioda, N., Sasaki, Y., Tagashira, H., Yawo, H., Yeh, J. Z., Sakagami, H., Narahashi, T. & Fukunaga, K., Feb 1 2018, In : Molecular Psychiatry. 23, 2, p. 211-221 11 p.

Research output: Contribution to journalArticle

Memantine
Alzheimer Disease
Adenosine Triphosphate
Calcium-Calmodulin-Dependent Protein Kinase Type 2
Long-Term Potentiation
9 Citations (Scopus)

CaMKII activity is essential for improvement of memory-related behaviors by chronic rivastigmine treatment

Moriguchi, S., Tagashira, H., Sasaki, Y., Yeh, J. Z., Sakagami, H., Narahashi, T. & Fukunaga, K., Jan 1 2014, In : Journal of neurochemistry. 128, 6, p. 927-937 11 p.

Research output: Contribution to journalArticle

Rivastigmine
Calcium-Calmodulin-Dependent Protein Kinase Type 2
Data storage equipment
Calcium-Calmodulin-Dependent Protein Kinase Type 4
Therapeutics
8 Citations (Scopus)

Immune-stimulated antitumor effect of different molecular weight polysaccharides from Monascus purpureus on human leukemic U937 cells

Chen, H. H., Chen, Y. Y., Yeh, J. Z., Jiang, C. M. & Wu, M. C., Apr 3 2014, In : CYTA - Journal of Food. 12, 2, p. 134-140 7 p.

Research output: Contribution to journalArticle

Monascus
Monascus purpureus
U937 Cells
Polysaccharides
polysaccharides
22 Citations (Scopus)

Antidepressants inhibit proton currents and tumor necrosis factor-α production in BV2 microglial cells

Song, J. H., Marszalec, W., Kai, L., Yeh, J. Z. & Narahashi, T., Jan 30 2012, In : Brain research. 1435, p. 15-23 9 p.

Research output: Contribution to journalArticle

Antidepressive Agents
Protons
Imipramine
Tumor Necrosis Factor-alpha
Proton-Motive Force
4 Citations (Scopus)

Application of immunomagnetic particles to enzyme-linked immunosorbent assay (ELISA) for improvement of detection sensitivity of hcg

Kuo, H. T., Yeh, J. Z., Wu, P. H., Jiang, C. M. & Wu, M. C., Oct 1 2012, In : Journal of Immunoassay and Immunochemistry. 33, 4, p. 377-387 11 p.

Research output: Contribution to journalArticle

Immunosorbents
Chorionic Gonadotropin
Assays
Enzyme-Linked Immunosorbent Assay
Enzymes