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Personal profile

Research Interests

My research program at Northwestern is dedicated to leveraging human-based discoveries to gain new biological insights. Areas of study include (1) the role of alternative RNA splicing events in mechanisms of lipid metabolism, atherosclerosis, and renal fibrosis and (2) functional interrogation of the molecular mechanisms by which novel genes identified through human genetics studies impact disease phenotypes. My group employs an integrative approach including cellular models derived from human induced pluripotent stem cells with genome-editing technology, animal-based mechanistic studies, and transcriptomic and proteomic discovery.

Certifications and Licenses

Nephrology
Internal Medicine

Training Experience

2010Internship, University of Colorado School of Medicine
2012Residency, University of Colorado School of Medicine
2015Fellowship, University of Pennsylvania Hospitals

Education/Academic qualification

MTR, University of Pennsylvania

… → 2017

MD, University of Texas

… → 2009

Research interests

  • Cardiovascular Diseases
  • Genomics
  • Molecular Genetics
  • Nephrology

Fingerprint Dive into the research topics where Jennie Lin is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
RNA Sequence Analysis Medicine & Life Sciences
Alternative Splicing Medicine & Life Sciences
Long Noncoding RNA Medicine & Life Sciences
Phenotype Medicine & Life Sciences
Kidney Medicine & Life Sciences
Genome-Wide Association Study Medicine & Life Sciences
Lipoprotein(a) Medicine & Life Sciences
Acute Kidney Injury Medicine & Life Sciences

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Grants 2018 2021

Macrophage Activation
Apolipoproteins
Kidney Diseases
Chronic Renal Insufficiency
Macrophages
Alternative Splicing
Macrophages
Phenotype
Atherosclerosis
Protein Isoforms

Research Output 2012 2019

  • 317 Citations
  • 15 Article
  • 2 Review article
  • 1 Comment/debate

Ten years in: APOL1 reaches beyond the kidney

Waitzman, J. S. & Lin, J., Jul 1 2019, In : Current opinion in nephrology and hypertension. 28, 4, p. 375-382 8 p.

Research output: Contribution to journalReview article

Kidney
Cardiovascular Diseases
Kidney Diseases
Chronic Renal Insufficiency
African Americans
Genome-Wide Association Study
Cardiovascular Diseases
Genotype
Phenotype
Genes
Genome-Wide Association Study
Cardiovascular Diseases
Genotype
Phenotype
Genes
6 Citations (Scopus)

Interrogation of nonconserved human adipose lincRNAs identifies a regulatory role of linc-ADAL in adipocyte metabolism

Zhang, X., Xue, C., Lin, J., Ferguson, J. F., Weiner, A., Liu, W., Han, Y., Hinkle, C., Li, W., Jiang, H., Gosai, S., Hachet, M., Garcia, B. A., Gregory, B. D., Soccio, R. E., Hogenesch, J. B., Seale, P., Li, M. & Reilly, M. P., Jun 20 2018, In : Science Translational Medicine. 10, 44, aar5987.

Research output: Contribution to journalArticle

Long Noncoding RNA
Adipocytes
Peroxisome Proliferator-Activated Receptors
Heterogeneous-Nuclear Ribonucleoprotein U
CCAAT-Enhancer-Binding Proteins

PennDiff: Detecting Differential Alternative Splicing and Transcription by RNA Sequencing

Hu, Y., Lin, J., Hu, J., Hu, G., Wang, K., Zhang, H., Reilly, M. P. & Li, M., Feb 20 2018, In : Bioinformatics.

Research output: Contribution to journalArticle

RNA Sequence Analysis
Alternative Splicing
Transcription
RNA
Sequencing