Jennifer Donglan Wu

  • 3413 Citations
1990 …2023

Research output per year

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Research Output

  • 3413 Citations
  • 45 Article
  • 6 Review article
  • 1 Comment/debate
  • 1 Editorial
2020

How else can we approach prostate cancer biomarker discovery?

Drake, R. R., Angel, P. M., Wu, J., Pachynski, R. K. & Ippolito, J. E., Feb 1 2020, In : Expert Review of Molecular Diagnostics. 20, 2, p. 123-125 3 p.

Research output: Contribution to journalEditorial

Open Access
1 Scopus citations
2019
Open Access
3 Scopus citations

CD73: An emerging checkpoint for cancer immunotherapy

Chen, S., Wainwright, D. A., Wu, J. D., Wan, Y., Matei, D. E., Zhang, Y. & Zhang, B., Jan 1 2019, In : Immunotherapy. 11, 11, p. 983-997 15 p.

Research output: Contribution to journalReview article

6 Scopus citations

Commentary: preclinical efficacy of immune-checkpoint monotherapy does not recapitulate corresponding biomarkers-based clinical predictions in glioblastoma by Garg et al. (2017)

Zhai, L., Ladomersky, E., Lauing, K. L., Wu, M., Scholtens, D. M., Savoor, R., Zhang, B., Wu, J. D., Horbinski, C., Lukas, R. V., Binder, D. C. & Wainwright, D. A., Mar 4 2019, In : OncoImmunology. 8, 3, 1548242.

Research output: Contribution to journalComment/debate

Past, Current, and Future of Immunotherapies for Prostate Cancer

Boettcher, A. N., Usman, A., Morgans, A., VanderWeele, D. J., Sosman, J. & Wu, J. D., Sep 11 2019, In : Frontiers in Oncology. 9, 884.

Research output: Contribution to journalReview article

Open Access
8 Scopus citations

Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging

Muñoz, D. P., Yannone, S. M., Daemen, A., Sun, Y., Vakar-Lopez, F., Kawahara, M., Freund, A. M., Rodier, F., Wu, J. D., Desprez, P. Y., Raulet, D. H., Nelson, P. S., van’t Veer, L. J., Campisi, J. & Coppé, J. P., Jan 1 2019, In : JCI Insight. 4, 14, e124716.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
Open Access
9 Scopus citations
2018

NKG2D and its ligands in cancer

Dhar, P. & Wu, J. D., Apr 2018, In : Current Opinion in Immunology. 51, p. 55-61 7 p.

Research output: Contribution to journalReview article

Open Access
17 Scopus citations

Tumor-infiltrating lymphocytes and colorectal cancer survival in Africa Namerican and Caucasian Patients

Wallace, K., Lewin, D. N., Sun, S., Spiceland, C. M., Rockey, D. C., Alekseyenko, A. V., Wu, J. D., Baron, J. A., Alberg, A. J. & Hill, E. G., Jul 2018, In : Cancer Epidemiology Biomarkers and Prevention. 27, 7, p. 755-761 7 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations
2017

Antibody-mediated neutralization of soluble MIC significantly enhances CTLA4 blockade therapy

Zhang, J., Liu, D., Li, G., Staveley-O'Carroll, K. F., Graff, J. N., Li, Z. & Wu, J. D., May 1 2017, In : Science advances. 3, 5, e1602133.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Pathological Role of Anti-CD4 Antibodies in HIV-Infected Immunologic Nonresponders Receiving Virus-Suppressive Antiretroviral Therapy

Luo, Z., Li, Z., Martin, L., Wan, Z., Meissner, E. G., Espinosa, E., Wu, H., Yu, X., Fu, P., Julia Westerink, M. A., Kilby, J. M., Wu, J., Huang, L., Heath, S. L., Li, Z. & Jiang, W., Jul 1 2017, In : Journal of Infectious Diseases. 216, 1, p. 82-91 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Prostate-specific IL-6 transgene autonomously induce prostate neoplasm through amplifying inflammation in the prostate and peri-prostatic adipose tissue

Liu, G., Zhang, J., Frey, L., Gang, X., Wu, K., Liu, Q., Lilly, M. & Wu, J., Jan 11 2017, In : Journal of Hematology and Oncology. 10, 1, 14.

Research output: Contribution to journalArticle

6 Scopus citations

Racial Differences in Stage IV Colorectal Cancer Survival in Younger and Older Patients

Wallace, K., DeToma, A., Lewin, D. N., Sun, S., Rockey, D., Britten, C. D., Wu, J. D., Ba, A., Alberg, A. J. & Hill, E. G., Sep 2017, In : Clinical colorectal cancer. 16, 3, p. 178-186 9 p.

Research output: Contribution to journalArticle

8 Scopus citations
2016
8 Scopus citations

Cooperative therapeutic anti-tumor effect of IL-15 agonist ALT-803 and co-targeting soluble NKG2D ligand sMIC

Basher, F., Jeng, E. K., Wong, H. & Wu, J., Jan 1 2016, In : Oncotarget. 7, 1, p. 814-830 17 p.

Research output: Contribution to journalArticle

8 Scopus citations

Surface expression of TGFβ docking receptor GARP promotes oncogenesis and immune tolerance in breast cancer

Metelli, A., Wu, B. X., Fugle, C. W., Rachidi, S., Sun, S., Zhang, Y., Wu, J., Tomlinson, S., Howe, P. H., Yang, Y., Garrett-Mayer, E., Liu, B. & Li, Z., Dec 15 2016, In : Cancer Research. 76, 24, p. 7106-7117 12 p.

Research output: Contribution to journalArticle

30 Scopus citations

The CXCL8-CXCR1/2 pathways in cancer

Liu, Q., Li, A., Tian, Y., Wu, J. D., Liu, Y., Li, T., Chen, Y., Han, X. & Wu, K., Oct 1 2016, In : Cytokine and Growth Factor Reviews. 31, p. 61-71 11 p.

Research output: Contribution to journalReview article

119 Scopus citations

The expression profile and clinic significance of the SIX family in non-small cell lung cancer

Liu, Q., Li, A., Tian, Y., Liu, Y., Li, T., Zhang, C., Wu, J. D., Han, X. & Wu, K., Nov 8 2016, In : Journal of Hematology and Oncology. 9, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

21 Scopus citations
2015

NKG2D ligands in tumor immunity: Two sides of a coin

Zhang, J., Basher, F. & Wu, J. D., Jan 1 2015, In : Frontiers in immunology. 6, MAR, 00097.

Research output: Contribution to journalArticle

73 Scopus citations

Nonblocking monoclonal antibody targeting soluble MIC revamps endogenous innate and adaptive antitumor responses and eliminates primary and metastatic tumors

Lu, S., Zhang, J., Liu, D., Li, G., Staveley-O'Carroll, K. F., Li, Z. & Wu, J. D., Nov 1 2015, In : Clinical Cancer Research. 21, 21, p. 4819-4830 12 p.

Research output: Contribution to journalArticle

13 Scopus citations

Soluble NKG2D ligand promotes MDSC expansion and skews macrophage to the alternatively activated phenotype

Xiao, G., Wang, X., Sheng, J., Lu, S., Yu, X. & Wu, J. D., 2015, In : Journal of Hematology and Oncology. 8, 1, 13.

Research output: Contribution to journalArticle

21 Scopus citations
2014

Immune chaperone gp96 drives the contributions of macrophages to inflammatory colon tumorigenesis

Morales, C., Rachidi, S., Hong, F., Sun, S., Ouyang, X., Wallace, C., Zhang, Y., Garret-Mayer, E., Wu, J., Liu, B. & Li, Z., Jan 15 2014, In : Cancer Research. 74, 2, p. 446-459 14 p.

Research output: Contribution to journalArticle

40 Scopus citations

Insulin-like growth factor receptor-1 (IGF-IR) as a target for prostate cancer therapy

Wu, J. & Yu, E., Sep 2014, In : Cancer and Metastasis Reviews. 33, 2-3, p. 607-617 11 p.

Research output: Contribution to journalReview article

22 Scopus citations

Proliferation and enrichment of CD133+ glioblastoma cancer stem cells on 3D chitosan-alginate scaffolds

Kievit, F. M., Florczyk, S. J., Leung, M. C., Wang, K., Wu, J. D., Silber, J. R., Ellenbogen, R. G., Lee, J. S. H. & Zhang, M., Nov 2014, In : Biomaterials. 35, 33, p. 9137-9143 7 p.

Research output: Contribution to journalArticle

58 Scopus citations
2013

Perturbation of NK cell peripheral homeostasis accelerates prostate carcinoma metastasis

Liu, G., Lu, S., Wang, X., Page, S. T., Higano, C. S., Plymate, S. R., Greenberg, N. M., Sun, S., Li, Z. & Wu, J. D., Oct 1 2013, In : Journal of Clinical Investigation. 123, 10, p. 4410-4422 13 p.

Research output: Contribution to journalArticle

56 Scopus citations
2012

3D porous chitosan-alginate scaffolds: A new matrix for studying prostate cancer cell-lymphocyte interactions in vitro

Florczyk, S. J., Liu, G., Kievit, F. M., Lewis, A. M., Wu, J. D. & Zhang, M., Sep 1 2012, In : Advanced healthcare materials. 1, 5, p. 590-599 10 p.

Research output: Contribution to journalArticle

45 Scopus citations
2011

Dihydrotestosterone administration does not increase intraprostatic androgen concentrations or alter prostate androgen action in healthy men: A randomized-controlled trial

Page, S. T., Lin, D. W., Mostaghel, E. A., Marck, B. T., Wright, J. L., Wu, J., Amory, J. K., Nelson, P. S. & Matsumoto, A. M., Feb 1 2011, In : Journal of Clinical Endocrinology and Metabolism. 96, 2, p. 430-437 8 p.

Research output: Contribution to journalArticle

52 Scopus citations

IL-6 promotes prostate tumorigenesis and progression through autocrine cross-activation of IGF-IR

Rojas, A., Liu, G., Coleman, I., Nelson, P. S., Zhang, M., Dash, R., Fisher, P. B., Plymate, S. R. & Wu, J. D., May 19 2011, In : Oncogene. 30, 20, p. 2345-2355 11 p.

Research output: Contribution to journalArticle

93 Scopus citations
2010

Chitosan-alginate scaffold culture system for hepatocellular carcinoma increases malignancy and drug resistance

Leung, M., Kievit, F. M., Florczyk, S. J., Veiseh, O., Wu, J., Park, J. O. & Zhang, M., Sep 1 2010, In : Pharmaceutical Research. 27, 9, p. 1939-1948 10 p.

Research output: Contribution to journalArticle

53 Scopus citations

Cutting edge: The membrane type matrix metalloproteinase MMP14 mediates constitutive shedding of MHC class I chain-related molecule a independent of a disintegrin and metalloproteinases

Liu, G., Atteridge, C. L., Wang, X., Lundgren, A. D. & Wu, J. D., Apr 1 2010, In : Journal of Immunology. 184, 7, p. 3346-3350 5 p.

Research output: Contribution to journalArticle

69 Scopus citations
2009

An six-amino acid motif in the α3 domain of MICA is the cancer therapeutic target to inhibit shedding

Wang, X., Lundgren, A. D., Singh, P., Goodlett, D. R., Plymate, S. R. & Wu, J. D., Sep 25 2009, In : Biochemical and Biophysical Research Communications. 387, 3, p. 476-481 6 p.

Research output: Contribution to journalArticle

19 Scopus citations

Obstructing shedding of the immunostimulatory MHC class i chain - Related gene B prevents tumor formation

Wu, J. D., Atteridge, C. L., Wang, X., Seya, T. & Plymate, S. R., Jan 15 2009, In : Clinical Cancer Research. 15, 2, p. 632-640 9 p.

Research output: Contribution to journalArticle

38 Scopus citations

Oxidative DNA damage in the prostate may predipose men to a higher risk of prostate cancer

Wu, J. D., Lin, D. W., Page, S. T., Lundgren, A. D., True, L. D. & Plymate, S. R., Jan 1 2009, In : Translational Oncology. 2, 1, p. 39-45 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

Transforming growth factor-β-stimulated clone-22 is an androgen-regulated gene that enhances apoptosis in prostate cancer following insulin-like growth factor-I receptor inhibition

Sprenger, C. C. T., Haugk, K., Sun, S., Coleman, I., Nelson, P. S., Vessella, R. L., Ludwig, D. L., Wu, J. D. & Plymate, S. R., Dec 15 2009, In : Clinical Cancer Research. 15, 24, p. 7634-7641 8 p.

Research output: Contribution to journalArticle

8 Scopus citations
2007

An antibody targeting the type I insulin-like growth factor receptor enhances the castration-induced response in androgen-dependent prostate cancer

Plymate, S. R., Haugk, K., Coleman, I., Woodke, L., Vessella, R., Nelson, P., Montgomery, R. B., Ludwig, D. L. & Wu, J. D., Nov 1 2007, In : Clinical Cancer Research. 13, 21, p. 6429-6439 11 p.

Research output: Contribution to journalArticle

50 Scopus citations
2006

Combined in vivo effect of A12, a type 1 insulin-like growth factor receptor antibody, and docetaxel against prostate cancer tumors

Wu, J. D., Haugk, K., Coleman, I., Woodke, L., Vessella, R., Nelson, P., Montgomery, R. B., Ludwig, D. L. & Plymate, S. R., Oct 15 2006, In : Clinical Cancer Research. 12, 20 PART 1, p. 6153-6160 8 p.

Research output: Contribution to journalArticle

76 Scopus citations

Effect of medical castration on CD4+CD25+ T cells, CD8+ T cell IFN-γ expression, and NK cells: A physiological role for testosterone and/or its metabolites

Page, S. T., Plymate, S. R., Bremner, W. J., Matsumoto, A. M., Hess, D. L., Lin, D. W., Amory, J. K., Nelson, P. S. & Wu, J. D., May 1 2006, In : American Journal of Physiology - Endocrinology and Metabolism. 290, 5, p. E856-E863

Research output: Contribution to journalArticle

88 Scopus citations

Interaction of IGF signaling and the androgen receptor in prostate cancer progression

Wu, J. D., Haugk, K., Woodke, L., Nelson, P., Coleman, I. & Plymate, S. R., Oct 1 2006, In : Journal of Cellular Biochemistry. 99, 2, p. 392-401 10 p.

Research output: Contribution to journalReview article

131 Scopus citations
2005

Counteracting MIC/NKG2D immunity by shedding MIC in prostate cancer

Wu, J. D., Higgins, L. M. & Steinle, A., Jul 6 2005, In : Enhancer - Biotherapy of Cancer. 3, 2, p. 18-20 3 p.

Research output: Contribution to journalArticle

In vivo effects of the human type I insulin-like growth factor receptor antibody A12 on androgen-dependent and androgen-independent xenograft human prostate tumors

Wu, J. D., Odman, A., Higgins, L. M., Haugk, K., Vessella, R., Ludwig, D. L. & Plymate, S. R., Apr 15 2005, In : Clinical Cancer Research. 11, 8, p. 3065-3074 10 p.

Research output: Contribution to journalArticle

137 Scopus citations
2004

Prevalent expression of the immunostimulatory MHC class I chain-related molecule is counteracted by shadding in prostate cancer

Wu, J. D., Higgins, L. M., Steinle, A., Cosman, D., Haugk, K. & Plymate, S. R., Aug 1 2004, In : Journal of Clinical Investigation. 114, 4, p. 560-568 9 p.

Research output: Contribution to journalArticle

245 Scopus citations
2003

Activation of Pro-apoptotic p38-MAPK Pathway in the Prostate Cancer Cell Line M12 Expressing a Truncated IGF-IR

Wu, J., Haugk, K. & Plymate, S. R., Nov 1 2003, In : Hormone and Metabolic Research. 35, 11-12, p. 751-757 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Intracellular retention of the MHC class I-related chain B ligand of NKG2D by the human cytomegalovirus UL16 glycoprotein

Wu, J., Chalupny, N. J., Manley, T. J., Riddell, S. R., Cosman, D. & Spies, T., Apr 15 2003, In : Journal of Immunology. 170, 8, p. 4196-4200 5 p.

Research output: Contribution to journalArticle

113 Scopus citations

Nuclear DNA degradation during heterokaryon incompatibility in Neurospora crassa

Marek, S. M., Wu, J., Glass, N. L., Gilchrist, D. G. & Bostock, R. M., Jan 1 2003, In : Fungal Genetics and Biology. 40, 2, p. 126-137 12 p.

Research output: Contribution to journalArticle

38 Scopus citations
2002

Nonself recognition is mediated by HET-C heterocomplex formation during vegetative incompatibility

Sarkar, S., Iyer, G., Wu, J. & Glass, N. L., Sep 16 2002, In : EMBO Journal. 21, 18, p. 4841-4850 10 p.

Research output: Contribution to journalArticle

30 Scopus citations

T cell antigen receptor engagement and specificity in the recognition of stress-inducible MHC class I-related chains by human epithelial γδ T cells

Wu, J., Groh, V. & Spies, T., Aug 1 2002, In : Journal of Immunology. 169, 3, p. 1236-1240 5 p.

Research output: Contribution to journalArticle

204 Scopus citations

Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation

Groh, V., Wu, J., Yee, C. & Spies, T., Oct 17 2002, In : Nature. 419, 6908, p. 734-738 5 p.

Research output: Contribution to journalArticle

1106 Scopus citations
2001
26 Scopus citations
1998
112 Scopus citations
1991

Immunogold labelling of the intermediate filamentlaminanuclear matrix system in hela and bhk21 cells

Jiao, R., Wu, D., Zhang, B., Cai, S. & Zhai, Z., Jun 1991, In : Journal of Electron Microscopy Technique. 18, 2, p. 126-134 9 p.

Research output: Contribution to journalArticle

10 Scopus citations