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Jeremy Alastair O'Sullivan

  • 193 Citations
20112020

Research output per year

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Personal profile

Research Interests

My lab focuses on the regulation of immune responses, especially those involving eosinophils, mast cells, and basophils including asthma, allergic diseases, and systemic mastocytosis, by members of the siglec family of cell-surface receptors as well as the use of these receptors as therapeutic targets through which to deliver agents selectively to these cell types.

Education/Academic qualification

PhD, The University of Chicago

… → 2011

Research interests

  • Allergies
  • Apoptosis
  • Asthma
  • Blood Cancer (leukemia and lymphomas)
  • Cell Adhesion Mechanisms
  • Immune Regulation
  • Immunology
  • Inflammation

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Grants

Identification of the Siglec-8-induced mode of eosinophil death and extracellular factors governing Siglec-6/8 expression and function

O'Sullivan, J. A.

University of California, San Diego, National Institute of Allergy and Infectious Diseases

9/1/18 → 8/31/19

Project: Research project

    • Targeting Mast Cells through Siglec-6

    Bochner, B. S., Bochner, B. S. & O'Sullivan, J. A.

    American Academy of Allergy, Asthma and Immunology

    7/1/17 → 6/30/19

    Project: Research project

    • Research Output

    • 193 Citations
    • 15 Article
    • 2 Review article

    Eosinophil and mast cell Siglecs: From biology to drug target

    O'Sullivan, J. A., Chang, A. T., Youngblood, B. A. & Bochner, B. S., Jan 1 2020, (Accepted/In press) In : Journal of Leukocyte Biology.

    Research output: Contribution to journal › Review article

    • 2 Scopus citations

    Frontline Science: Superior mouse eosinophil depletion in vivo targeting transgenic Siglec-8 instead of endogenous Siglec-F: Mechanisms and pitfalls

    Knuplez, E., Krier-Burris, R., Cao, Y., Marsche, G., O'Sullivan, J. & Bochner, B. S., Jan 1 2020, (Accepted/In press) In : Journal of Leukocyte Biology.

    Research output: Contribution to journal › Article

    • 1 Scopus citations

    Single-site, five-year experience with human eosinophil isolation by density gradient centrifugation and CD16 immunomagnetic negative separation

    Cao, Y., Shin, S., Carroll, D. J., O'Sullivan, J. A. & Bochner, B. S., Apr 10 2020, In : BMC Research Notes. 13, 1, 211.

    Research output: Contribution to journal › Article

    Open Access

    • A Sulfonamide Sialoside Analogue for Targeting Siglec-8 and-F on Immune Cells

    Nycholat, C. M., Duan, S., Knuplez, E., Worth, C., Elich, M., Yao, A., O'Sullivan, J., McBride, R., Wei, Y., Fernandes, S. M., Zhu, Z., Schnaar, R. L., Bochner, B. S. & Paulson, J. C., Sep 11 2019, In : Journal of the American Chemical Society. 141, 36, p. 14032-14037 6 p.

    Research output: Contribution to journal › Article

    • 3 Scopus citations

    Eosinophils and eosinophil-associated diseases: An update

    O'Sullivan, J. A. & Bochner, B. S., Feb 2018, In : Journal of Allergy and Clinical Immunology. 141, 2, p. 505-517 13 p.

    Research output: Contribution to journal › Article

    • 22 Scopus citations