Jeremy Alastair O'Sullivan

  • 144 Citations
20112019
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Personal profile

Research Interests

My lab focuses on the regulation of immune responses, especially those involving eosinophils, mast cells, and basophils including asthma, allergic diseases, and systemic mastocytosis, by members of the siglec family of cell-surface receptors as well as the use of these receptors as therapeutic targets through which to deliver agents selectively to these cell types.

Education/Academic qualification

PhD, University of Chicago

… → 2011

Research interests

  • Allergies
  • Apoptosis
  • Asthma
  • Blood Cancer (leukemia and lymphomas)
  • Cell Adhesion Mechanisms
  • Immune Regulation
  • Immunology
  • Inflammation

Fingerprint Dive into the research topics where Jeremy Alastair O'Sullivan is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 3 Similar Profiles
Sialic Acid Binding Immunoglobulin-like Lectins Medicine & Life Sciences
Eosinophils Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
Transforming Growth Factors Medicine & Life Sciences
Mast Cells Medicine & Life Sciences
Lectins Medicine & Life Sciences
Saliva Medicine & Life Sciences
Immunoglobulins Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2017 2019

Sialic Acid Binding Immunoglobulin-like Lectins
Mast Cells
Endocytosis
Systemic Mastocytosis
Cell Surface Receptors

Research Output 2011 2018

  • 144 Citations
  • 12 Article
  • 1 Review article
11 Citations (Scopus)

Eosinophils and eosinophil-associated diseases: An update

O'Sullivan, J. A. & Bochner, B. S., Feb 1 2018, In : Journal of Allergy and Clinical Immunology. 141, 2, p. 505-517 13 p.

Research output: Contribution to journalArticle

Eosinophils
Allergy and Immunology
3 Citations (Scopus)

Frontline Science: Characterization of a novel mouse strain expressing human Siglec-8 only on eosinophils

O'Sullivan, J. A., Wei, Y., Carroll, D. J., Moreno-Vinasco, L., Cao, Y., Zhang, F., Lee, J. J., Zhu, Z. & Bochner, B. S., Jul 1 2018, In : Journal of Leukocyte Biology. 104, 1, p. 11-19 9 p.

Research output: Contribution to journalArticle

Sialic Acid Binding Immunoglobulin-like Lectins
Eosinophils
Mast Cells
CXCR3 Receptors
Death Domain Receptors
2 Citations (Scopus)

Identification of a Siglec-F+ granulocyte-macrophage progenitor

Bolden, J. E., Lucas, E. C., Zhou, G., O'Sullivan, J. A., de Graaf, C. A., McKenzie, M. D., Di Rago, L., Baldwin, T. M., Shortt, J., Alexander, W. S., Bochner, B. S., Ritchie, M. E., Hilton, D. J. & Fairfax, K. A., Jul 1 2018, In : Journal of Leukocyte Biology. 104, 1, p. 123-133 11 p.

Research output: Contribution to journalArticle

Sialic Acid Binding Immunoglobulin-like Lectins
Granulocyte-Macrophage Progenitor Cells
Interleukin-5 Receptors
Eosinophils
Population
11 Citations (Scopus)

Leveraging Siglec-8 endocytic mechanisms to kill human eosinophils and malignant mast cells

O'Sullivan, J. A., Carroll, D. J., Cao, Y., Salicru, A. N. & Bochner, B. S., May 1 2018, In : Journal of Allergy and Clinical Immunology. 141, 5, p. 1774-1785.e7

Research output: Contribution to journalArticle

Saliva
Eosinophils
Lectins
Mast Cells
Immunoglobulins
7 Citations (Scopus)

Sialic acid–binding immunoglobulin-like lectin 8 (Siglec-8) is an activating receptor mediating β2-integrin–dependent function in human eosinophils

Carroll, D. J., O'Sullivan, J. A., Nix, D. B., Cao, Y., Tiemeyer, M. & Bochner, B. S., Jun 1 2018, In : Journal of Allergy and Clinical Immunology. 141, 6, p. 2196-2207 12 p.

Research output: Contribution to journalArticle

Saliva
Eosinophils
Lectins
Immunoglobulins
Sialic Acid Binding Immunoglobulin-like Lectins