Grants per year
Personal profile
Research Interests
My lab focuses on the regulation of immune responses, especially those involving eosinophils, mast cells, and basophils including asthma, allergic diseases, and systemic mastocytosis, by members of the siglec family of cell-surface receptors as well as the use of these receptors as therapeutic targets through which to deliver agents selectively to these cell types.
Education/Academic qualification
PhD, University of Chicago
… → 2011
Research interests
- Allergies
- Apoptosis
- Asthma
- Blood Cancer (leukemia and lymphomas)
- Cell Adhesion Mechanisms
- Immune Regulation
- Immunology
- Inflammation
Fingerprint Dive into the research topics where Jeremy Alastair O'Sullivan is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 3 Similar Profiles
Sialic Acid Binding Immunoglobulin-like Lectins
Medicine & Life Sciences
Eosinophils
Medicine & Life Sciences
T-Lymphocytes
Medicine & Life Sciences
Transforming Growth Factors
Medicine & Life Sciences
Mast Cells
Medicine & Life Sciences
Lectins
Medicine & Life Sciences
Saliva
Medicine & Life Sciences
Immunoglobulins
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2017 2019
Identification of the Siglec-8-induced mode of eosinophil death and extracellular factors governing Siglec-6/8 expression and function
University of California, San Diego, National Institute of Allergy and Infectious Diseases
9/1/18 → 8/31/19
Project: Research project
Sialic Acid Binding Immunoglobulin-like Lectins
Eosinophils
Mast Cells
Cell Death
Food
Targeting Mast Cells through Siglec-6
Bochner, B. S., Bochner, B. S. & O'Sullivan, J. A.
American Academy of Allergy, Asthma and Immunology
7/1/17 → 6/30/19
Project: Research project
Sialic Acid Binding Immunoglobulin-like Lectins
Mast Cells
Endocytosis
Systemic Mastocytosis
Cell Surface Receptors
Research Output 2011 2018
11
Citations
(Scopus)
Eosinophils and eosinophil-associated diseases: An update
O'Sullivan, J. A. & Bochner, B. S., Feb 1 2018, In : Journal of Allergy and Clinical Immunology. 141, 2, p. 505-517 13 p.Research output: Contribution to journal › Article
Eosinophils
Allergy and Immunology
3
Citations
(Scopus)
Frontline Science: Characterization of a novel mouse strain expressing human Siglec-8 only on eosinophils
O'Sullivan, J. A., Wei, Y., Carroll, D. J., Moreno-Vinasco, L., Cao, Y., Zhang, F., Lee, J. J., Zhu, Z. & Bochner, B. S., Jul 1 2018, In : Journal of Leukocyte Biology. 104, 1, p. 11-19 9 p.Research output: Contribution to journal › Article
Sialic Acid Binding Immunoglobulin-like Lectins
Eosinophils
Mast Cells
CXCR3 Receptors
Death Domain Receptors
2
Citations
(Scopus)
Identification of a Siglec-F+ granulocyte-macrophage progenitor
Bolden, J. E., Lucas, E. C., Zhou, G., O'Sullivan, J. A., de Graaf, C. A., McKenzie, M. D., Di Rago, L., Baldwin, T. M., Shortt, J., Alexander, W. S., Bochner, B. S., Ritchie, M. E., Hilton, D. J. & Fairfax, K. A., Jul 1 2018, In : Journal of Leukocyte Biology. 104, 1, p. 123-133 11 p.Research output: Contribution to journal › Article
Sialic Acid Binding Immunoglobulin-like Lectins
Granulocyte-Macrophage Progenitor Cells
Interleukin-5 Receptors
Eosinophils
Population
11
Citations
(Scopus)
Leveraging Siglec-8 endocytic mechanisms to kill human eosinophils and malignant mast cells
O'Sullivan, J. A., Carroll, D. J., Cao, Y., Salicru, A. N. & Bochner, B. S., May 1 2018, In : Journal of Allergy and Clinical Immunology. 141, 5, p. 1774-1785.e7Research output: Contribution to journal › Article
Saliva
Eosinophils
Lectins
Mast Cells
Immunoglobulins
7
Citations
(Scopus)
Sialic acid–binding immunoglobulin-like lectin 8 (Siglec-8) is an activating receptor mediating β2-integrin–dependent function in human eosinophils
Carroll, D. J., O'Sullivan, J. A., Nix, D. B., Cao, Y., Tiemeyer, M. & Bochner, B. S., Jun 1 2018, In : Journal of Allergy and Clinical Immunology. 141, 6, p. 2196-2207 12 p.Research output: Contribution to journal › Article
Saliva
Eosinophils
Lectins
Immunoglobulins
Sialic Acid Binding Immunoglobulin-like Lectins