Grants per year
Personal profile
Research Interests
My lab focuses on the regulation of immune responses, especially those involving eosinophils, mast cells, and basophils including asthma, allergic diseases, and systemic mastocytosis, by members of the siglec family of cell-surface receptors as well as the use of these receptors as therapeutic targets through which to deliver agents selectively to these cell types.
Education/Academic qualification
PhD, The University of Chicago
… → 2011
Research interests
- Allergies
- Apoptosis
- Asthma
- Blood Cancer (leukemia and lymphomas)
- Cell Adhesion Mechanisms
- Immune Regulation
- Immunology
- Inflammation
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Grants
- 2 Finished
-
Targeting Mast Cells through Siglec-6
Bochner, B. S., Bochner, B. S. & O'Sullivan, J. A.
American Academy of Allergy, Asthma and Immunology
7/1/17 → 6/30/19
Project: Research project
Research Output
-
Eosinophil and mast cell Siglecs: From biology to drug target
O'Sullivan, J. A., Chang, A. T., Youngblood, B. A. & Bochner, B. S., Jul 1 2020, In: Journal of Leukocyte Biology. 108, 1, p. 73-81 9 p.Research output: Contribution to journal › Review article › peer-review
11 Scopus citations -
Frontline Science: Superior mouse eosinophil depletion in vivo targeting transgenic Siglec-8 instead of endogenous Siglec-F: Mechanisms and pitfalls
Knuplez, E., Krier-Burris, R., Cao, Y., Marsche, G., O'Sullivan, J. & Bochner, B. S., Jul 1 2020, In: Journal of Leukocyte Biology. 108, 1, p. 43-58 16 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Single-site, five-year experience with human eosinophil isolation by density gradient centrifugation and CD16 immunomagnetic negative separation
Cao, Y., Shin, S., Carroll, D. J., O'Sullivan, J. A. & Bochner, B. S., Apr 10 2020, In: BMC Research Notes. 13, 1, 211.Research output: Contribution to journal › Article › peer-review
Open Access -
A Sulfonamide Sialoside Analogue for Targeting Siglec-8 and-F on Immune Cells
Nycholat, C. M., Duan, S., Knuplez, E., Worth, C., Elich, M., Yao, A., O'Sullivan, J., McBride, R., Wei, Y., Fernandes, S. M., Zhu, Z., Schnaar, R. L., Bochner, B. S. & Paulson, J. C., Sep 11 2019, In: Journal of the American Chemical Society. 141, 36, p. 14032-14037 6 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Eosinophils and eosinophil-associated diseases: An update
O'Sullivan, J. A. & Bochner, B. S., Feb 2018, In: Journal of Allergy and Clinical Immunology. 141, 2, p. 505-517 13 p.Research output: Contribution to journal › Article › peer-review
27 Scopus citations