Grants per year
Personal profile
Research Interests
My lab focuses on the regulation of immune responses, especially those involving eosinophils, mast cells, and basophils including asthma, allergic diseases, and systemic mastocytosis, by members of the siglec family of cell-surface receptors as well as the use of these receptors as therapeutic targets through which to deliver agents selectively to these cell types.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Immunology, PhD, University of Chicago
… → 2011
Research interests
- Allergies
- Apoptosis
- Asthma
- Blood Cancer (leukemia and lymphomas)
- Cell Adhesion Mechanisms
- Immune Regulation
- Immunology
- Inflammation
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Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Project 4 Bruce Bochner for SP0070487
Bochner, B. S. & O'Sullivan, J. A.
National Institute of Allergy and Infectious Diseases
7/15/22 → 4/30/23
Project: Research project
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Project 3 Elena Martinelli for SP0070487
Bochner, B. S., O'Sullivan, J. A. & Martinelli, E.
National Institute of Allergy and Infectious Diseases
7/15/22 → 4/30/27
Project: Research project
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Targeting Mast Cells through Siglec-6
O'Sullivan, J. A., Bochner, B. S. & Bochner, B. S.
American Academy of Allergy, Asthma and Immunology
7/1/17 → 6/30/19
Project: Research project
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Functional and Phenotypic Characterization of Siglec-6 on Human Mast Cells
Robida, P. A., Rische, C. H., Morgenstern, N. B. B., Janarthanam, R., Cao, Y., Krier-Burris, R. A., Korver, W., Xu, A., Luu, T., Schanin, J., Leung, J., Rothenberg, M. E., Wechsler, J. B., Youngblood, B. A., Bochner, B. S. & O’Sullivan, J. A., Apr 1 2022, In: Cells. 11, 7, 1138.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Siglecs in allergy and asthma
Bochner, B. S., O'Sullivan, J. A., Chang, A. T. & Youngblood, B. A., 2022, (Accepted/In press) In: Molecular Aspects of Medicine. 101104.Research output: Contribution to journal › Review article › peer-review
2 Scopus citations -
Discovery, function, and therapeutic targeting of siglec-8
Youngblood, B. A., Leung, J., Falahati, R., Williams, J., Schanin, J., Brock, E. C., Singh, B., Chang, A. T., O’sullivan, J. A., Schleimer, R. P., Tomasevic, N., Bebbington, C. R. & Bochner, B. S., Jan 2021, In: Cells. 10, 1, p. 1-14 14 p., 19.Research output: Contribution to journal › Review article › peer-review
Open Access27 Scopus citations -
Siglec-8 Signals Through a Non-Canonical Pathway to Cause Human Eosinophil Death In Vitro
Carroll, D. J., Cao, Y., Bochner, B. S. & O'Sullivan, J. A., Oct 11 2021, In: Frontiers in immunology. 12, 737988.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Eosinophil and mast cell Siglecs: From biology to drug target
O'Sullivan, J. A., Chang, A. T., Youngblood, B. A. & Bochner, B. S., Jul 1 2020, In: Journal of Leukocyte Biology. 108, 1, p. 73-81 9 p.Research output: Contribution to journal › Review article › peer-review
29 Scopus citations