Jian-Jun Wei

  • 3519 Citations
1991 …2023
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Personal profile

Research Interests

My major research interests are on identification of molecular biomarkers that are associated with tumor growth and progression in benign and malignant uterine smooth muscle tumors. In addition, I am interested in characterization of the role of microRNAs in the pathogenesis of benign and malignant tumors in women's reproductive organs through regulation of the target gene expression.

Certifications and Licenses

Anatomic Pathology & Clinical Pathology

Training Experience

2003Residency, New York University Medical Center
2004Fellowship, New York University Medical Center

Education/Academic qualification

MD, Shandong Medical University

… → 1985

Keywords

  • Cancer Genetics
  • Gene Regulation
  • Women's Health / Women's Reproductive Health
  • Cancer: Female Reproductive System (ovary, cervix, uterus)

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  • 7 Similar Profiles
Leiomyoma Medicine & Life Sciences
Ovarian Neoplasms Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
MicroRNAs Medicine & Life Sciences
Genes Medicine & Life Sciences
Prostatic Neoplasms Medicine & Life Sciences
Carcinoma Medicine & Life Sciences
Fallopian Tubes Medicine & Life Sciences

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Grants 2001 2023

PCF Shared Resource

Wei, J.

National Cancer Institute

8/10/187/31/23

Project: Research project

Neoplasms
Medicine
Research
Population
Neoplastic Stem Cells
Ovarian Neoplasms
Lipids
Heterografts
Raman Spectrum Analysis

Research Output 1991 2019

Hydropic leiomyoma: a distinct variant of leiomyoma closely related to HMGA2 overexpression

Griffin, B. B., Ban, Y., Lu, X. & Wei, J-J., Feb 1 2019, In : Human pathology. 84, p. 164-172 9 p.

Research output: Contribution to journalArticle

Leiomyoma
Edema
Neoplasms
Fluorescence In Situ Hybridization
Smooth Muscle Tumor

Application of ex-vivo spheroid model system for the analysis of senescence and senolytic phenotypes in uterine leiomyoma

Xie, J., Xu, X., Yin, P., Li, Y., Guo, H., Kujawa, S., Chakravarti, D., Bulun, S. E., Kim, J. J. & Wei, J-J., Dec 1 2018, In : Laboratory Investigation. 98, 12, p. 1575-1587 13 p.

Research output: Contribution to journalArticle

Leiomyoma
Systems Analysis
Phenotype
Genes
Myometrium
1 Citation (Scopus)

Comparative analysis of AKT and the related biomarkers in uterine leiomyomas with MED12, HMGA2, and FH mutations

Xie, J., Ubango, J., Ban, Y., Chakravarti, D., Kim, J. J. & Wei, J-J., Oct 1 2018, In : Genes Chromosomes and Cancer. 57, 10, p. 485-494 10 p.

Research output: Contribution to journalArticle

Leiomyoma
Biomarkers
Mutation
Genes
Up-Regulation
2 Citations (Scopus)

Fumarate Hydratase Mutations and Alterations in Leiomyoma with Bizarre Nuclei

Zhang, Q., Poropatich, K., Ubago, J., Xie, J., Xu, X., Frizzell, N., Kim, J. J., Kong, B. & Wei, J-J., Sep 1 2018, In : International Journal of Gynecological Pathology. 37, 5, p. 421-430 10 p.

Research output: Contribution to journalArticle

Fumarate Hydratase
Leiomyoma
Mutation
Smooth Muscle Tumor
Myometrium
2 Citations (Scopus)

Increased oxidative stress mediates the antitumor effect of PARP inhibition in ovarian cancer

Hou, D., Liu, Z., Xu, X., Liu, Q., Zhang, X., Kong, B., Wei, J-J., Gong, Y. & Shao, C., Jul 1 2018, In : Redox Biology. 17, p. 99-111 13 p.

Research output: Contribution to journalArticle

Oxidative stress
Ovarian Neoplasms
DNA Damage
Oxidative Stress
DNA