Grants per year
Personal profile
Research Interests
My major research interests are on identification of molecular biomarkers that are associated with tumor growth and progression in benign and malignant uterine smooth muscle tumors. In addition, I am interested in characterization of the role of microRNAs in the pathogenesis of benign and malignant tumors in women's reproductive organs through regulation of the target gene expression.
Certifications and Licenses
Anatomic Pathology & Clinical Pathology |
Training Experience
2003 | Residency, New York University Medical Center |
2004 | Fellowship, New York University Medical Center |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
MD, Medicine, Shandong Medical University
… → 1985
Research interests keywords
- Cancer Genetics
- Gene Regulation
- Women's Health / Women's Reproductive Health
- Cancer: Female Reproductive System (ovary, cervix, uterus)
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Collaborations and top research areas from the last five years
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Roles of GATA Transcription Factors in Endometriosis
Chakravarti, D. (PD/PI), Adli, M. (Co-Investigator), Bulun, S. E. (Co-Investigator), Milad, M. P. (Co-Investigator), Parker, B. L. (Co-Investigator) & Wei, J.-J. (Co-Investigator)
National Institute of Child Health and Human Development
2/5/24 → 11/30/28
Project: Research project
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Epigenetic study of oral HPV infection-associated oral cancer in people living with HIV in Nigeria
Hou, L. (PD/PI), Hou, L. (PD/PI), Murphy, R. L. (PD/PI), Murphy, R. L. (PD/PI), Cooper, L. A. D. (Co-Investigator), Wang, J. (Co-Investigator), Wang, J. (Co-Investigator), Wei, J.-J. (Co-Investigator), Wei, J.-J. (Co-Investigator), Zheng, Y. (Co-Investigator) & Zheng, Y. (Co-Investigator)
9/16/22 → 8/31/26
Project: Research project
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West Africa Self-Sampling HPV Based Cervical Cancer Control Program (WA-SS-HCCP) for WLWHA: Barriers, challenges, and needs
Hou, L. (PD/PI), Hou, L. (PD/PI), Maiga, M. (PD/PI), Maiga, M. (PD/PI), Kocherginsky, M. (Co-Investigator), Kocherginsky, M. (Co-Investigator), Murphy, R. L. (Co-Investigator), Murphy, R. L. (Co-Investigator), Wei, J.-J. (Co-Investigator), Wei, J.-J. (Co-Investigator), Zheng, Y. (Co-Investigator) & Zheng, Y. (Co-Investigator)
9/7/22 → 8/31/27
Project: Research project
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SPORE in Prostate Cancer
Abdulkadir, S. A. (PD/PI), Abdulkadir, S. A. (PD/PI), Hussain, M. (Co-PD/PI), Hussain, M. (Co-PD/PI), Catalona, W. J. (Co-Investigator), Catalona, W. J. (Co-Investigator), Chakravarti, D. (Co-Investigator), Chakravarti, D. (Co-Investigator), Cooper, L. A. D. (Co-Investigator), Kim, K.-Y. A. (Co-Investigator), Kim, K.-Y. A. (Co-Investigator), Kim, K.-Y. A. (Co-Investigator), Morgans, A. K. (Co-Investigator), Morgans, A. K. (Co-Investigator), Murphy, A. B. (Co-Investigator), Murphy, A. B. (Co-Investigator), Ross, A. E. (Co-Investigator), Schiltz, G. E. (Co-Investigator), Schiltz, G. E. (Co-Investigator), VanderWeele, D. J. (Co-Investigator), Wei, J.-J. (Co-Investigator), Wei, J.-J. (Co-Investigator), Yang, R. (Co-Investigator), Yang, R. (Co-Investigator), Yu, J. (Co-Investigator), Yu, J. (Co-Investigator), Kocherginsky, M. (Other), Kocherginsky, M. (Other), Leikin, R. G. (Other), Leikin, R. G. (Other), Sosman, J. A. (Other), Sosman, J. A. (Other), Wu, J. D. (Other), Wu, J. D. (Other), Yang, X. J. (Other), Yang, X. J. (Other), Yang, R. (Other), Zhao, C. (Other) & Zhao, C. (Other)
9/1/21 → 7/31/26
Project: Research project
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Infection-Associated Cancer Research Training Program in Mali
Hou, L. (PD/PI), Hou, L. (PD/PI), Maiga, M. (PD/PI), Maiga, M. (PD/PI), Joyce, B. (Co-Investigator), Kim, K.-Y. A. (Co-Investigator), Kim, K.-Y. A. (Co-Investigator), Murphy, R. L. (Co-Investigator), Murphy, R. L. (Co-Investigator), Wei, J.-J. (Co-Investigator), Wei, J.-J. (Co-Investigator), Zhang, B. (Co-Investigator) & Zhang, B. (Co-Investigator)
7/1/21 → 6/30/26
Project: Research project
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Cell-free DNA methylation-based inflammation score as a marker for hepatocellular carcinoma among people living with HIV
Kim, K., Zheng, Y., Joyce, B. T., Nannini, D. R., Wang, J., Qu, Y., Hawkins, C. A., Okeke, E., Lesi, O. A., Roberts, L. R., Gursel, D. B., Abdulkareem, F. B., Akanmu, A. S., Duguru, M. J., Davwar, P., Nyam, D. P., Adisa, R. A., Imade, G., Wei, J. J. & Kocherginsky, M. & 9 others, , 2024, (Accepted/In press) In: Hepatology International. e0282539.Research output: Contribution to journal › Article › peer-review
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Editorial: New strategies to overcome platinum resistance in ovarian cancer
Wei, J. J. & Martinelli, F., 2024, In: Frontiers in Oncology. 14, 1390760.Research output: Contribution to journal › Editorial › peer-review
Open Access -
Engineered uterine primary myometrial cells with high-mobility group AT-hook 2 overexpression display a leiomyoma-like transcriptional and epigenomic phenotype
Saini, P., Holmes, A. G., Wei, J.-J., Parker, J. B. & Chakravarti, D., Nov 2024, In: F and S Science. 5, 4, p. 352-368 17 p.Research output: Contribution to journal › Article › peer-review
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Genomic characterization and histologic analysis of uterine leiomyosarcoma arising from leiomyoma with bizarre nuclei
Felicelli, C., Lu, X., Coty-Fattal, Z., Yue, F., Yin, P., Schipma, M. J., Kim, J. J., Jennings, L. J., Bulun, S. E. & Wei, J.-J., 2024, (Accepted/In press) In: Journal of Pathology.Research output: Contribution to journal › Article › peer-review
Open Access -
Preclinical Evaluation of NTX-301, a Novel DNA Hypomethylating Agent in Ovarian Cancer
Wang, Y., Situ, X., Cardenas, H., Siu, E., Alhunayan, S. A., Keathley, R., Tanner, E. J., Wei, J. J., Tan, Y., Dessai, C. V. P., Cheng, J. X. & Matei, D., Mar 15 2024, In: Clinical Cancer Research. 30, 6, p. 1175-1188 14 p.Research output: Contribution to journal › Article › peer-review
Datasets
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Additional file 1: Figure S1. of Synuclein-γ (SNCG) expression in ovarian cancer is associated with high-risk clinicopathologic disease
Strohl, A. (Creator), Mori, K. (Creator), Akers, S. (Creator), Bshara, W. (Contributor), Buttin, B. (Creator), Frederick, P. J. (Creator), Helenowski, I. B. (Creator), Morrison, C. D. (Creator), Odunsi, K. (Contributor), Schink, J. C. (Creator), Scholtens, D. M. (Creator), Wei, J.-J. (Creator) & Kim, J. J. (Contributor), figshare, 2016
DOI: 10.6084/m9.figshare.c.3621737_d1, https://springernature.figshare.com/articles/presentation/Additional_file_1_Figure_S1_of_Synuclein-_SNCG_expression_in_ovarian_cancer_is_associated_with_high-risk_clinicopathologic_disease/4396022
Dataset
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Additional file 2 of Myometrial oxidative stress drives MED12 mutations in leiomyoma
Li, Y. (Creator), Xu, X. (Creator), Asif, H. (Creator), Feng, Y. (Creator), Kohrn, B. F. (Creator), Kennedy, S. R. (Creator), Kim, J. J. (Creator), Wei, J.-J. (Creator) & Garbutt, A. (Contributor), figshare, 2022
DOI: 10.6084/m9.figshare.20362734, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_Myometrial_oxidative_stress_drives_MED12_mutations_in_leiomyoma/20362734
Dataset
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Myometrial oxidative stress drives MED12 mutations in leiomyoma
Li, Y. (Creator), Xu, X. (Creator), Asif, H. (Creator), Feng, Y. (Creator), Kohrn, B. F. (Creator), Kennedy, S. R. (Creator), Kim, J. J. (Creator) & Wei, J.-J. (Creator), figshare, 2022
DOI: 10.6084/m9.figshare.c.6113616, https://springernature.figshare.com/collections/Myometrial_oxidative_stress_drives_MED12_mutations_in_leiomyoma/6113616
Dataset
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Dual Pten/p53 suppression enhances Notch signaling and sarcoma progression
Guijarro, M. V. (Contributor), Dahiya, S. (Contributor), Danielson, L. S. (Contributor), Segura, M. F. (Contributor), Vales-Lara, F. M. (Contributor), Menendez, S. (Contributor), Popiolek, D. (Contributor), Wei, J. J. (Contributor), Zavadil, J. (Contributor), Cordon-Cardo, C. (Contributor), Pandolfi, P. P. (Contributor) & Hernando, E. (Contributor), Gene Expression Omnibus, Nov 7 2012
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE42103
Dataset
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Synuclein-γ (SNCG) expression in ovarian cancer is associated with high-risk clinicopathologic disease
Strohl, A. (Creator), Mori, K. (Creator), Akers, S. (Creator), Bshara, W. (Contributor), Buttin, B. (Creator), Frederick, P. J. (Creator), Helenowski, I. B. (Creator), Morrison, C. D. (Creator), Odunsi, K. (Contributor), Schink, J. C. (Creator), Scholtens, D. M. (Creator), Wei, J.-J. (Creator) & Kim, J. J. (Contributor), figshare, 2016
DOI: 10.6084/m9.figshare.c.3621737, https://figshare.com/collections/Synuclein-_SNCG_expression_in_ovarian_cancer_is_associated_with_high-risk_clinicopathologic_disease/3621737
Dataset