• Source: Scopus

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Personal profile

Research Interests

The primary research focus of the lab is to understand aberrant transcriptional and epigenetic regulation of prostate cancer. We utilize high-throughput genomic techniques in combination with bioinformatics/statistical analysis to generate hypothetical concepts. We then test these hypotheses using traditional molecular or cellular biological approaches and examine the functional relevance of innovative mechanisms using in vitro cell line and in vivo mouse models. Transcription factors of particular interest to us include androgen receptor (AR), FoxA1, Polycomb group protein (EZH2), and the Ets family protein (ERG). Based on the genetics and epigenetics of the disease, we also pursue translational research to define diagnostic / prognostic biomarkers and to pursue novel therapeutics strategies for treating advanced prostate cancer.

Education/Academic qualification

PhD, University of Michigan

… → 2004

MD, Peking University

… → 1998

Research interests

  • Cancer Biology
  • Endocrinology
  • Genomics
  • Prostate Cancer


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