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Research Output 2002 2020

  • 11348 Citations
  • 65 Article
  • 8 Review article
  • 3 Comment/debate
  • 2 Letter
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Article
2020

BMI1 is directly regulated by androgen receptor to promote castration-resistance in prostate cancer

Zhu, S., Zhao, D., Li, C., Li, Q., Jiang, W., Liu, Q., Wang, R., Fazli, L., Li, Y., Zhang, L., Yi, Y., Meng, Q., Wang, W., Wang, G., Zhang, M., Zu, X., Zhao, W., Deng, T., Yu, J., Dong, X. & 2 others, Chen, K. & Cao, Q., Jan 2 2020, In : Oncogene. 39, 1, p. 17-29 13 p.

Research output: Contribution to journalArticle

Castration
Androgen Receptors
Lymphoma
Prostatic Neoplasms
Neoplasms
2019
5 Citations (Scopus)

Activation of MAPK Signaling by CXCR7 leads to enzalutamide resistance in prostate cancer

Li, S., Fong, K. W., Gritsina, G., Zhang, A., Zhao, C., Kim, J., Sharp, A., Yuan, W., Aversa, C., Yang, X. J., Nelson, P. S., Feng, F. Y., Chinnaiyan, A. M., De Bono, J. S., Morrissey, C., Rettig, M. B. & Yu, J., Jan 1 2019, In : Cancer Research. 79, 10, p. 2580-2592 13 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Castration
Androgen Receptor Antagonists
MDV 3100
Androgen Antagonists
5 Citations (Scopus)

N-Myc-mediated epigenetic reprogramming drives lineage plasticity in advanced prostate cancer

Berger, A., Brady, N. J., Bareja, R., Robinson, B., Conteduca, V., Augello, M. A., Puca, L., Ahmed, A., Dardenne, E., Lu, X., Hwang, I., Bagadion, A. M., Sboner, A., Elemento, O., Paik, J., Yu, J., Barbieri, C. E., Dephoure, N., Beltran, H. & Rickman, D. S., Sep 3 2019, In : Journal of Clinical Investigation. 129, 9, p. 3924-3940 17 p.

Research output: Contribution to journalArticle

Open Access
Epigenomics
Prostatic Neoplasms
Androgen Receptors
Histone Code
Organoids
14 Citations (Scopus)

Targeting FOXA1-mediated repression of TGF-β signaling suppresses castration-resistant prostate cancer progression

Song, B., Park, S. H., Zhao, J. C., Fong, K. W., Li, S., Lee, Y., Yang, Y. A., Sridhar, S., Lu, X., Abdulkadir, S. A., Vessella, R. L., Morrissey, C., Kuzel, T. M., Catalona, W., Yang, X. & Yu, J., Feb 1 2019, In : Journal of Clinical Investigation. 129, 2, p. 569-582 14 p.

Research output: Contribution to journalArticle

LY-2157299
Castration
Androgen Antagonists
Prostatic Neoplasms
Epithelial-Mesenchymal Transition
2018
17 Citations (Scopus)

BMI1 regulates androgen receptor in prostate cancer independently of the polycomb repressive complex 1

Zhu, S., Zhao, D., Yan, L., Jiang, W., Kim, J. S., Gu, B., Liu, Q., Wang, R., Xia, B., Zhao, J. C., Song, G., Mi, W., Wang, R. F., Shi, X., Lam, H. M., Dong, X., Yu, J., Chen, K. & Cao, Q., Dec 1 2018, In : Nature communications. 9, 1, 500.

Research output: Contribution to journalArticle

Polycomb Repressive Complex 1
Androgen Receptors
Prostatic Neoplasms
cancer
Castration
17 Citations (Scopus)

Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator

Kim, J., Lee, Y., Lu, X., Song, B., Fong, K. W., Cao, Q., Licht, J. D., Zhao, J. C. & Yu, J., Dec 4 2018, In : Cell reports. 25, 10, p. 2808-2820.e4

Research output: Contribution to journalArticle

Methylation
Androgen Receptors
Transcription
Polycomb Repressive Complex 2
Genes
7 Citations (Scopus)

PRDM4 mediates YAP-induced cell invasion by activating leukocyte-specific integrin β2 expression

Liu, H., Dai, X., Cao, X., Yan, H., Ji, X., Zhang, H., Shen, S., Si, Y., Zhang, H., Chen, J., Li, L., Zhao, J. C., Yu, J., Feng, X. H. & Zhao, B., Jun 2018, In : EMBO Reports. 19, 6, e45180.

Research output: Contribution to journalArticle

Integrins
Leukocytes
Proteins
Transcription Factors
Deregulation
5 Citations (Scopus)

TRIM28 protects TRIM24 from SPOP-mediated degradation and promotes prostate cancer progression

Fong, K. W., Zhao, J. C., Song, B., Zheng, B. & Yu, J., Dec 1 2018, In : Nature communications. 9, 1, 5007.

Research output: Contribution to journalArticle

Open Access
progressions
Prostatic Neoplasms
cancer
degradation
Degradation
6 Citations (Scopus)

USP22 deficiency leads to myeloid leukemia upon oncogenic Kras activation through a PU.1-dependent mechanism

Melo-Cardenas, J., Xu, Y., Wei, J., Tan, C., Kong, S., Gao, B., Montauti, E., Kirsammer, G., Licht, J. D., Yu, J., Ji, P., Crispino, J. D. & Fang, D., Jul 26 2018, In : Blood. 132, 4, p. 423-434 12 p.

Research output: Contribution to journalArticle

Myeloid Leukemia
Ubiquitin
Peptide Hydrolases
Chemical activation
Acute Myeloid Leukemia
2017
18 Citations (Scopus)

CD95/Fas Increases Stemness in Cancer Cells by Inducing a STAT1-Dependent Type I Interferon Response

Qadir, A. S., Ceppi, P., Brockway, S., Law, C., Mu, L., Khodarev, N. N., Kim, J., Zhao, C., Putzbach, W., Murmann, A. E., Chen, Z., Chen, W., Liu, X., Salomon, A. R., Liu, H., Weichselbaum, R. R., Yu, J. & Peter, M. E., Mar 7 2017, In : Cell reports. 18, 10, p. 2373-2386 14 p.

Research output: Contribution to journalArticle

STAT1 Transcription Factor
Interferon Type I
Cells
Neoplastic Stem Cells
Stem cells
34 Citations (Scopus)

FOXA1 inhibits prostate cancer neuroendocrine differentiation

Kim, J., Jin, H., Zhao, J. C., Yang, Y. A., Li, Y., Yang, X., Dong, X. & Yu, J., Jul 13 2017, In : Oncogene. 36, 28, p. 4072-4080 9 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Interleukin-8
MAP Kinase Signaling System
Phosphopyruvate Hydratase
Prostate
15 Citations (Scopus)

PADI2-mediated citrullination promotes prostate cancer progression

Wang, L., Song, G., Zhang, X., Feng, T., Pan, J., Chen, W., Yang, M., Bai, X., Pang, Y., Yu, J., Han, J. & Han, B., Nov 1 2017, In : Cancer Research. 77, 21, p. 5755-5768 14 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Androgen Receptors
Castration
Androgens
Histones
9 Citations (Scopus)

Polycomb-mediated disruption of an androgen receptor feedback loop drives castration-resistant prostate cancer

Fong, K. W., Zhao, J. C., Kim, J., Li, S., Yang, Y. A., Song, B., Rittie, L., Hu, M., Yang, X., Perbal, B. & Yu, J., Jan 15 2017, In : Cancer Research. 77, 2, p. 412-422 11 p.

Research output: Contribution to journalArticle

Castration
Androgen Receptors
Prostatic Neoplasms
Polycomb-Group Proteins
Growth
2016
29 Citations (Scopus)

FOXA1 acts upstream of GATA2 and AR in hormonal regulation of gene expression

Zhao, C., Fong, K. W., Jin, H. J., Yang, Y. A., Kim, J. & Yu, J., Aug 18 2016, In : Oncogene. 35, 33, p. 4335-4344 10 p.

Research output: Contribution to journalArticle

Androgen Receptors
Gene Expression Regulation
Prostatic Neoplasms
Gene Expression
Hormones
13 Citations (Scopus)

FOXA1 potentiates lineage-specific enhancer activation through modulating TET1 expression and function

Yang, Y. A., Zhao, J. C., Fong, K. W., Kim, J., Li, S., Song, C., Song, B., Zheng, B., He, C. & Yu, J., Sep 30 2016, In : Nucleic acids research. 44, 17, p. 8153-8164 12 p.

Research output: Contribution to journalArticle

Epigenomics
Histones
Methylation
Transcriptional Activation
Lysine
6 Citations (Scopus)

KAT8 regulates androgen signaling in prostate cancer cells

Kim, J. Y., Yu, J., Abdulkadir, S. A. & Chakravarti, D., Aug 2016, In : Molecular Endocrinology. 30, 8, p. 925-936 12 p.

Research output: Contribution to journalArticle

Androgen Receptors
Androgens
Prostatic Neoplasms
Histones
Transcriptional Activation
147 Citations (Scopus)

LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer

Xue, X., Yang, Y. A., Zhang, A., Fong, K. W., Kim, J., Song, B., Li, S., Zhao, J. C. & Yu, J., May 1 2016, In : Oncogene. 35, 21, p. 2746-2755 10 p.

Research output: Contribution to journalArticle

Tamoxifen
Estrogen Receptors
Breast Neoplasms
Long Noncoding RNA
Hormones
22 Citations (Scopus)

The common stress responsive transcription factor ATF3 binds genomic sites enriched with p300 and H3K27ac for transcriptional regulation

Zhao, J., Li, X., Guo, M., Yu, J. & Yan, C., May 4 2016, In : BMC Genomics. 17, 1, 335.

Research output: Contribution to journalArticle

Activating Transcription Factor 3
DNA Damage
Gene Expression
Genes
Camptothecin
2015
48 Citations (Scopus)

A miR-130a-YAP positive feedback loop promotes organ size and tumorigenesis

Shen, S., Guo, X., Yan, H., Lu, Y., Ji, X., Li, L., Liang, T., Zhou, D., Feng, X. H., Zhao, J. C., Yu, J., Gong, X. G., Zhang, L. & Zhao, B., Sep 4 2015, In : Cell Research. 25, 9, p. 997-1012 16 p.

Research output: Contribution to journalArticle

Organ Size
Carcinogenesis
MicroRNAs
Drosophila
Liver
121 Citations (Scopus)

LncRNA HOTAIR Enhances the Androgen-Receptor-Mediated Transcriptional Program and Drives Castration-Resistant Prostate Cancer

Zhang, A., Zhao, J. C., Kim, J., Fong, K. W., Yang, Y. A., Chakravarti, D., Mo, Y. Y. & Yu, J., Oct 6 2015, In : Cell reports. 13, 1, p. 209-221 13 p.

Research output: Contribution to journalArticle

Castration
Androgen Receptors
Long Noncoding RNA
Androgens
Prostatic Neoplasms
33 Citations (Scopus)

miR-573 inhibits prostate cancer metastasis by regulating epithelialmesenchymal transition

Wang, L., Song, G., Tan, W., Qi, M., Zhang, L., Chan, J., Yu, J., Han, J. & Han, B., Jan 1 2015, In : Oncotarget. 6, 34, p. 35978-35990 13 p.

Research output: Contribution to journalArticle

Receptor, Fibroblast Growth Factor, Type 1
Prostatic Neoplasms
Neoplasm Metastasis
Epithelial-Mesenchymal Transition
Down-Regulation
19 Citations (Scopus)

The role of TXNDC5 in castration-resistant prostate cancer - Involvement of androgen receptor signaling pathway

Wang, L., Song, G., Chang, X., Tan, W., Pan, J., Zhu, X., Liu, Z., Qi, M., Yu, J. & Han, B., Sep 3 2015, In : Oncogene. 34, 36, p. 4735-4745 11 p.

Research output: Contribution to journalArticle

Thioredoxins
Castration
Androgen Receptors
Prostatic Neoplasms
Androgens
2014
27 Citations (Scopus)

CCN3/NOV gene expression in human prostate cancer is directly suppressed by the androgen receptor

Wu, L., Runkle, C., Jin, H. J., Yu, J., Li, J., Yang, X., Kuzel, T., Lee, C. & Yu, J., Jan 23 2014, In : Oncogene. 33, 4, p. 504-513 10 p.

Research output: Contribution to journalArticle

Wilms Tumor
Androgen Receptors
Prostatic Neoplasms
Gene Expression
Androgens
72 Citations (Scopus)

Cooperativity and equilibrium with FOXA1 define the androgen receptor transcriptional program

Jin, H. J., Zhao, J. C., Wu, L., Kim, J. & Yu, J., May 29 2014, In : Nature communications. 5, 3972.

Research output: Contribution to journalArticle

Androgen Receptors
chromatin
Androgens
Chromatin
Response Elements
2013
70 Citations (Scopus)

Androgen receptor-independent function of FoxA1 in prostate cancer metastasis

Jin, H. J., Zhao, J. C., Ogden, I., Bergan, R. C. & Yu, J., Jun 15 2013, In : Cancer Research. 73, 12, p. 3725-3736 12 p.

Research output: Contribution to journalArticle

Androgen Receptors
Prostatic Neoplasms
Neoplasm Metastasis
Cell Movement
Prostate
75 Citations (Scopus)

BRCA1 is a negative modulator of the PRC2 complex

Wang, L., Zeng, X., Chen, S., Ding, L., Zhong, J., Zhao, C., Wang, L., Sarver, A., Koller, A., Zhi, J., Ma, Y., Yu, J., Chen, J. & Huang, H., May 29 2013, In : EMBO Journal. 32, 11, p. 1584-1597 14 p.

Research output: Contribution to journalArticle

Polycomb Repressive Complex 2
Modulators
Stem cells
Breast Neoplasms
Cell Differentiation
43 Citations (Scopus)

ERG is a critical regulator of Wnt/LEF1 signaling in prostate cancer

Wu, L., Zhao, J. C., Kim, J., Jin, H. J., Wang, C. Y. & Yu, J., Oct 1 2013, In : Cancer Research. 73, 19, p. 6068-6079 12 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Catenins
Genetic Translocation
Wnt Signaling Pathway
Epithelial-Mesenchymal Transition
69 Citations (Scopus)

The histone methyltransferase MMSET/WHSC1 activates TWIST1 to promote an epithelial-mesenchymal transition and invasive properties of prostate cancer

Ezponda, T., Popovic, R., Shah, M. Y., Martinez-Garcia, E., Zheng, Y., Min, D. J., Will, C., Neri, A., Kelleher, N. L., Yu, J. & Licht, J. D., Jun 6 2013, In : Oncogene. 32, 23, p. 2882-2890 9 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Prostatic Neoplasms
Epigenomics
Lysine
Cell Movement
32 Citations (Scopus)

TMPRSS2-ERG gene fusions induce prostate tumorigenesis by modulating microRNA miR-200c

Kim, J., Wu, L., Zhao, C., Jin, H. & Yu, J., Nov 4 2013, In : Oncogene. 33, 44, p. 5183-5192 10 p.

Research output: Contribution to journalArticle

Gene Fusion
Serine Proteases
MicroRNAs
Prostate
Prostatic Neoplasms
2012
392 Citations (Scopus)

Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis

Zhao, B., Li, L., Wang, L., Wang, C. Y., Yu, J. & Guan, K. L., Jan 1 2012, In : Genes and Development. 26, 1, p. 54-68 15 p.

Research output: Contribution to journalArticle

Anoikis
Cytoskeleton
Neoplasms
Proteins
Extracellular Matrix
69 Citations (Scopus)

Cooperation between Polycomb and androgen receptor during oncogenic transformation

Zhao, J. C., Yu, J., Runkle, C., Wu, L., Hu, M., Wu, D., Liu, J. S., Wang, Q., Qin, Z. S. & Yu, J., Feb 1 2012, In : Genome research. 22, 2, p. 322-331 10 p.

Research output: Contribution to journalArticle

Androgen Receptors
Androgens
Prostate
Polycomb-Group Proteins
Gene Expression
2011
157 Citations (Scopus)

Coordinated Regulation of Polycomb Group Complexes through microRNAs in Cancer

Cao, Q., Mani, R. S., Ateeq, B., Dhanasekaran, S. M., Asangani, I. A., Prensner, J. R., Kim, J. H., Brenner, J. C., Jing, X., Cao, X., Wang, R., Li, Y., Dahiya, A., Wang, L., Pandhi, M., Lonigro, R. J., Wu, Y. M., Tomlins, S. A., Palanisamy, N., Qin, Z. & 4 others, Yu, J., Maher, C. A., Varambally, S. & Chinnaiyan, A. M., Aug 16 2011, In : Cancer Cell. 20, 2, p. 187-199 13 p.

Research output: Contribution to journalArticle

MicroRNAs
Neoplasms
Polycomb-Group Proteins
Neoplastic Stem Cells
Epigenomics
128 Citations (Scopus)

Deep sequencing reveals distinct patterns of DNA methylation in prostate cancer

Kim, J. H., Dhanasekaran, S. M., Prensner, J. R., Cao, X., Robinson, D., Kalyana-Sundaram, S., Huang, C., Shankar, S., Jing, X., Iyer, M., Hu, M., Sam, L., Grasso, C., Maher, C. A., Palanisamy, N., Mehra, R., Kominsky, H. D., Siddiqui, J., Yu, J., Qin, Z. S. & 1 others, Chinnaiyan, A. M., Jul 1 2011, In : Genome research. 21, 7, p. 1028-1041 14 p.

Research output: Contribution to journalArticle

High-Throughput Nucleotide Sequencing
DNA Methylation
Methylation
Prostatic Neoplasms
CpG Islands
59 Citations (Scopus)

Definition of a FoxA1 cistrome that is crucial for G 1 to S-phase cell-cycle transit in castration-resistant prostate cancer

Zhang, C., Wang, L., Wu, D., Chen, H., Chen, Z., Thomas-Ahner, J. M., Zynger, D. L., Eeckhoute, J., Yu, J., Luo, J., Brown, M., Clinton, S. K., Nephew, K. P., Huang, T. H. M., Li, W. & Wang, Q., Nov 1 2011, In : Cancer Research. 71, 21, p. 6738-6748 11 p.

Research output: Contribution to journalArticle

Castration
S Phase
Prostatic Neoplasms
Cell Cycle
Cyclins
287 Citations (Scopus)

Mechanistic Rationale for Inhibition of Poly(ADP-Ribose) Polymerase in ETS Gene Fusion-Positive Prostate Cancer

Brenner, J. C., Ateeq, B., Li, Y., Yocum, A. K., Cao, Q., Asangani, I. A., Patel, S., Wang, X., Liang, H., Yu, J., Palanisamy, N., Siddiqui, J., Yan, W., Cao, X., Mehra, R., Sabolch, A., Basrur, V., Lonigro, R. J., Yang, J., Tomlins, S. A. & 8 others, Maher, C. A., Elenitoba-Johnson, K. S. J., Hussain, M., Navone, N. M., Pienta, K. J., Varambally, S., Feng, F. Y. & Chinnaiyan, A. M., May 17 2011, In : Cancer Cell. 19, 5, p. 664-678 15 p.

Research output: Contribution to journalArticle

Poly(ADP-ribose) Polymerases
Gene Fusion
Prostatic Neoplasms
DNA
Polynucleotide 5'-Hydroxyl-Kinase
49 Citations (Scopus)

The DEK oncoprotein is a Su(var) that is essential to heterochromatin integrity

Kappes, F., Waldmann, T., Mathew, V., Yu, J., Zhang, L., Khodadoust, M. S., Chinnaiyan, A. M., Luger, K., Erhardt, S., Schneider, R. & Markovitz, D. M., Apr 1 2011, In : Genes and Development. 25, 7, p. 673-678 6 p.

Research output: Contribution to journalArticle

Heterochromatin
Oncogene Proteins
Euchromatin
Genomic Instability
Gene Expression Regulation
2010
514 Citations (Scopus)

An Integrated Network of Androgen Receptor, Polycomb, and TMPRSS2-ERG Gene Fusions in Prostate Cancer Progression

Yu, J., Yu, J., Mani, R. S., Cao, Q., Brenner, C. J., Cao, X., Wang, X., Wu, L., Li, J., Hu, M., Gong, Y., Cheng, H., Laxman, B., Vellaichamy, A., Shankar, S., Li, Y., Dhanasekaran, S. M., Morey, R., Barrette, T., Lonigro, R. J. & 4 others, Tomlins, S. A., Varambally, S., Qin, Z. S. & Chinnaiyan, A. M., May 18 2010, In : Cancer Cell. 17, 5, p. 443-454 12 p.

Research output: Contribution to journalArticle

Gene Fusion
Androgen Receptors
Prostatic Neoplasms
Polycomb-Group Proteins
High-Throughput Nucleotide Sequencing
66 Citations (Scopus)

Cdc42-interacting protein 4 promotes breast cancer cell invasion and formation of invadopodia through activation of N-WASp

Pichot, C. S., Arvanitis, C., Hartig, S. M., Jensen, S. A., Bechill, J., Marzouk, S., Yu, J., Frost, J. A. & Corey, S. J., Nov 1 2010, In : Cancer Research. 70, 21, p. 8347-8356 10 p.

Research output: Contribution to journalArticle

cdc42 GTP-Binding Protein
Breast Neoplasms
Gelatin
Cell Movement
Cell Line
47 Citations (Scopus)

ERG cooperates with androgen receptor in regulating trefoil factor 3 in prostate cancer disease progression

Rickman, D. S., Chen, Y. B., Banerjee, S., Pan, Y., Yu, J., Vuong, T., Perner, S., Lafargue, C. J., Mertz, K. D., Setlur, S. R., Sircar, K., Chinnaiyan, A. M., Bismar, T. A., Rubin, M. A. & Demichelis, F., Jan 1 2010, In : Neoplasia. 12, 12, p. 1031-1040 10 p.

Research output: Contribution to journalArticle

Androgen Receptors
Disease Progression
Castration
Prostatic Neoplasms
Chromatin Immunoprecipitation
80 Citations (Scopus)

HPeak: An HMM-based algorithm for defining read-enriched regions in ChIP-Seq data

Qin, Z. S., Yu, J., Shen, J., Maher, C. A., Hu, M., Kalyana-Sundaram, S., Yu, J. & Chinnaiyan, A. M., Jul 2 2010, In : BMC bioinformatics. 11, 369.

Research output: Contribution to journalArticle

Chromatin Immunoprecipitation
Chromatin
Hidden Markov models
Markov Model
Model-based
76 Citations (Scopus)

On the detection and refinement of transcription factor binding sites using ChIP-Seq data

Hu, M., Yu, J., Taylor, J. M. G., Chinnaiyan, A. M. & Qin, Z. S., Jan 7 2010, In : Nucleic acids research. 38, 7, p. 2154-2167 14 p., gkp1180.

Research output: Contribution to journalArticle

Chromatin Immunoprecipitation
Transcription Factors
Binding Sites
Technology
High-Throughput Nucleotide Sequencing
55 Citations (Scopus)

The neuronal repellent SLIT2 is a target for repression by EZH2 in prostate cancer

Yu, J., Cao, Q., Yu, J., Wu, L., Dallol, A., Li, J., Chen, G., Grasso, C., Cao, X., Lonigro, R. J., Varambally, S., Mehra, R., Palanisamy, N., Wu, J. Y., Latif, F. & Chinnaiyan, A. M., Sep 30 2010, In : Oncogene. 29, 39, p. 5370-5380 11 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Neoplasms
Prostate
Polycomb-Group Proteins
DNA Methylation
385 Citations (Scopus)

The role of YAP transcription coactivator in regulating stem cell self-renewal and differentiation

Lian, I., Kim, J., Okazawa, H., Zhao, J., Zhao, B., Yu, J., Chinnaiyan, A., Israel, M. A., Goldstein, L. S. B., Abujarour, R., Ding, S. & Guan, K. L., Jun 1 2010, In : Genes and Development. 24, 11, p. 1106-1118 13 p.

Research output: Contribution to journalArticle

Proteins
Embryonic Stem Cells
Stem Cells
Cell Differentiation
Cell Self Renewal
2009
579 Citations (Scopus)

Androgen Receptor Regulates a Distinct Transcription Program in Androgen-Independent Prostate Cancer

Wang, Q., Li, W., Zhang, Y., Yuan, X., Xu, K., Yu, J., Chen, Z., Beroukhim, R., Wang, H., Lupien, M., Wu, T., Regan, M. M., Meyer, C. A., Carroll, J. S., Manrai, A. K., Jänne, O. A., Balk, S. P., Mehra, R., Han, B., Chinnaiyan, A. M. & 8 others, Rubin, M. A., True, L., Fiorentino, M., Fiore, C., Loda, M., Kantoff, P. W., Liu, X. S. & Brown, M., Jul 23 2009, In : Cell. 138, 2, p. 245-256 12 p.

Research output: Contribution to journalArticle

Androgen Receptors
Transcription
Androgens
Prostatic Neoplasms
Genes
259 Citations (Scopus)

Chimeric transcript discovery by paired-end transcriptome sequencing

Maher, C. A., Palanisamy, N., Brenner, J. C., Cao, X., Kalyana-Sundaram, S., Luo, S., Khrebtukova, I., Barrette, T. R., Grasso, C., Yu, J., Lonigro, R. J., Schroth, G., Kumar-Sinha, C. & Chinnaiyan, A. M., Jul 28 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 30, p. 12353-12358 6 p.

Research output: Contribution to journalArticle

Gene Fusion
Transcriptome
Cataloging
Neoplasms
Messenger RNA
1422 Citations (Scopus)

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

Sreekumar, A., Poisson, L. M., Rajendiran, T. M., Khan, A. P., Cao, Q., Yu, J., Laxman, B., Mehra, R., Lonigro, R. J., Li, Y., Nyati, M. K., Ahsan, A., Kalyana-Sundaram, S., Han, B., Cao, X., Byun, J., Omenn, G. S., Ghosh, D., Pennathur, S., Alexander, D. C. & 6 others, Berger, A., Shuster, J. R., Wei, J. T., Varambally, S., Beecher, C. & Chinnaiyan, A. M., Feb 12 2009, In : Nature. 457, 7231, p. 910-914 5 p.

Research output: Contribution to journalArticle

Sarcosine
Metabolomics
Prostatic Neoplasms
Prostate
Glycine
37 Citations (Scopus)

Proteomic interrogation of androgen action in prostate cancer cells reveals roles of aminoacyl tRNA synthetases

Vellaichamy, A., Sreekumar, A., Strahler, J. R., Rajendiran, T., Yu, J., Varambally, S., Li, Y., Omenn, G. S., Chinnaiyan, A. M. & Nesvizhskii, A. I., Sep 18 2009, In : PloS one. 4, 9, e7075.

Research output: Contribution to journalArticle

aminoacyl tRNA ligases
Amino Acyl-tRNA Synthetases
prostatic neoplasms
androgens
Proteomics
2008
122 Citations (Scopus)

A fluorescence in situ hybridization screen for E26 transformation-specific aberrations: Identification of DDX5-ETV4 fusion protein in prostate cancer

Han, B., Mehra, R., Dhanasekaran, S. M., Yu, J., Menon, A., Lonigro, R. J., Wang, X., Gong, Y., Wang, L., Shankar, S., Laxman, B., Shah, R. B., Varambally, S., Palanisamy, N., Tomlins, S. A., Kumar-Sinha, C. & Chinnaiyan, A. M., Sep 15 2008, In : Cancer Research. 68, 18, p. 7629-7637 9 p.

Research output: Contribution to journalArticle

Fluorescence In Situ Hybridization
Gene Fusion
Prostatic Neoplasms
Proteins
Androgens
27 Citations (Scopus)

A transcriptional fingerprint of estrogen in human breast cancer predicts patient survival

Yu, J., Yu, J., Cordero, K. E., Johnson, M. D., Ghosh, D., Rae, J. M., Chinnaiyan, A. M. & Lippman, M. E., Jan 2008, In : Neoplasia. 10, 1, p. 79-88 10 p.

Research output: Contribution to journalArticle

Dermatoglyphics
Estrogen Receptors
Estrogens
Breast Neoplasms
Survival
784 Citations (Scopus)

Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer

Varambally, S., Cao, Q., Mani, R. S., Shankar, S., Wang, X., Ateeq, B., Laxman, B., Cao, X., Jing, X., Ramnarayanan, K., Brenner, J. C., Yu, J., Kim, J. H., Han, B., Tan, P., Kumar-Sinha, C., Lonigro, R. J., Palanisamy, N., Maher, C. A. & Chinnaiyan, A. M., Dec 12 2008, In : Science. 322, 5908, p. 1695-1699 5 p.

Research output: Contribution to journalArticle

MicroRNAs
Neoplasms
Epigenomics
Gene Silencing
histone methyltransferase